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Common allergies linked to antibiotic use in infancy, health researchers say
With "hundreds of millions" of people suffering from allergies, Professor Dr Stuart Turvey and his colleagues wanted to get to the bottom of it.
Source: Daily Express - Health - August 30, 2023 Category: Consumer Health News Source Type: news

Murine model identifies tropomyosin as IgE cross-reactive protein between house dust mite and coho salmon that possibly contributes to the development of salmon allergy
ConclusionOur results showed IgE cross-reactivity of tropomyosin between Dermatophagoides and coho salmon which illustrates salmon allergy following sensitization with the house dust mite Dermatophagoides. Our method for identifying IgE cross-reactive allergens will help understand the underlying mechanisms of food allergies.
Source: Frontiers in Immunology - August 30, 2023 Category: Allergy & Immunology Source Type: research

An outbreak of anaphylactic transfusion reactions to group B plasma and platelets and its possible relationship to Alpha-Gal syndrome
DISCUSSION: AGS is an emerging problem which may have implications for blood transfusion practice. Avoidance of blood group B antigen containing components may be prudent in non-blood group B patients with established AGS. Investigation for AGS should be considered in the evaluation of anaphylactic transfusion reactions.PMID:37642435 | DOI:10.1111/trf.17521
Source: Transfusion - August 29, 2023 Category: Hematology Authors: Colleen W Gilstad Kathleen Conry-Cantilena Roya Zarpak Anne F Eder Source Type: research

An Overview of Nanotechnological Approaches for the Diagnosis and Treatment of Allergic Illness
Curr Pharm Des. 2023 Aug 28. doi: 10.2174/1381612829666230828104015. Online ahead of print.ABSTRACTAllergies are a major health issue. Allergen avoidance, antihistamines, and corticosteroids do not treat the pathology's causes, therefore long-term therapy is essential. Long-term allergen-specific immunotherapy builds immune tolerance to the allergen. Unfortunately, immunotherapies for all allergens are not available, and adverse reactions during therapy, especially in severely allergic persons, remain a worry. In this regard, cell and bio- or nanomaterial-based allergy treatments are promising. This overview covers the mos...
Source: Current Pharmaceutical Design - August 29, 2023 Category: Drugs & Pharmacology Authors: Bhupendra Sharma Rohitas Deshmukh Source Type: research

An outbreak of anaphylactic transfusion reactions to group B plasma and platelets and its possible relationship to Alpha-Gal syndrome
DISCUSSION: AGS is an emerging problem which may have implications for blood transfusion practice. Avoidance of blood group B antigen containing components may be prudent in non-blood group B patients with established AGS. Investigation for AGS should be considered in the evaluation of anaphylactic transfusion reactions.PMID:37642435 | DOI:10.1111/trf.17521
Source: Transfusion - August 29, 2023 Category: Hematology Authors: Colleen W Gilstad Kathleen Conry-Cantilena Roya Zarpak Anne F Eder Source Type: research

Genes, Vol. 14, Pages 1724: A Review of the Epigenetic Clock: Emerging Biomarkers for Asthma and Allergic Disease
Daley DNA methylation (DNAm) is a dynamic, age-dependent epigenetic modification that can be used to study interactions between genetic and environmental factors. Environmental exposures during critical periods of growth and development may alter DNAm patterns, leading to increased susceptibility to diseases such as asthma and allergies. One method to study the role of DNAm is the epigenetic clock—an algorithm that uses DNAm levels at select age-informative Cytosine-phosphate-Guanine (CpG) dinucleotides to predict epigenetic age (EA). The difference between EA and calendar age (CA) is termed epigenetic ag...
Source: Genes - August 29, 2023 Category: Genetics & Stem Cells Authors: Denitsa Vasileva Celia M. T. Greenwood Denise Daley Tags: Review Source Type: research

Viruses, Vol. 15, Pages 1832: Low CCL2 and CXCL8 Production and High Prevalence of Allergies in Children with Microcephaly Due to Congenital Zika Syndrome
This study investigated the peripheral dysregulation of immune mediators in children with microcephaly due to CZS. Gene expression quantified by qPCR in whole blood samples showed an increase in IFNγ and IL-13 transcripts in children affected with microcephaly compared to the control group. The microcephaly group exhibited significantly decreased CCL2 and CXCL8 levels in serum, quantified by CBA assay. An allergic profile questionnaire revealed a high prevalence of allergies in the microcephaly group. In accordance, elevated serum IgE level measured by the Proquantum Immunoassay was observed in children affec...
Source: Viruses - August 29, 2023 Category: Virology Authors: Wallace Pitanga Bezerra Amanda Costa Ayres Salmeron Anna Cl áudia Calvielli Castelo Branco Ingryd Camara Morais Val éria Soraya de Farias Sales Paula Renata Lima Machado Janeusa Trindade Souto Jos élio Maria Galvão de Araújo Paulo Marcos da Matta Gue Tags: Article Source Type: research

Avoid Expensive Detox Scams
Detoxing continues to be a hot topic in Hollywood and across social media sites. Celebrities like Kim Kardashian and Gwyneth Paltrow promote cleansing as a way to counter everything from weight gain to the effects of too many cocktails the night before. It’s gotten really out of hand… Today, you can find over-the-counter detox kits in every drug store across the country. They’re a huge business. Last year, sales of detox products topped $100 million. But sadly, you’re being sold a bill of goods regarding these kits. Now, don’t get me wrong, toxins are a huge problem… Your environment has changed dramatically in...
Source: Al Sears, MD Natural Remedies - August 28, 2023 Category: Complementary Medicine Authors: Jacob Tags: Health Source Type: news

Anaphylactic shock induced by polyethylene glycol after bowel preparation for the colorectal cancer surgery: A case report
CONCLUSION: While allergic reactions to PEG are rare, they can be life-threatening. Therefore, it is crucial for clinicians to be aware of this possibility and to diagnose and resuscitate patients immediately.PMID:37637691 | PMC:PMC10450373 | DOI:10.12998/wjcc.v11.i23.5589
Source: Clinical Colorectal Cancer - August 28, 2023 Category: Cancer & Oncology Authors: Go Woon Park Nahyeon Park Jung Cheol Kuk Eung Jin Shin Dae Ro Lim Source Type: research

A qualitative investigation into vaccine hesitancy and confidence among people managing allergy
Vaccine hesitancy is multifactorial, and among atopic individuals, is exacerbated by documented, but rare, cases of allergic reactions to coronavirus disease 2019 (COVID-19) vaccines.1 –3 Furthermore, conflicting information regarding the safety of COVID-19 vaccines may have caused confusion among individuals with a history of severe allergies. We performed semistructured qualitative interviews to better understand how some adults and families managing allergy perceive vaccine m essaging and what influences their decisions to be vaccinated.
Source: Annals of Allergy, Asthma and Immunology - August 28, 2023 Category: Allergy & Immunology Authors: Ayel Luis R. Batac, Kaitlyn A. Merrill, Michael A. Golding, Elissa M. Abrams, Philippe B égin, Moshe Ben-Shoshan, Erika Ladouceur, Leslie E. Roos, Vladan Protudjer, Jennifer L.P. Protudjer Tags: Letters Source Type: research

A qualitative investigation into vaccine hesitancy and confidence amongst people managing allergy
Vaccine hesitancy has a multifactorial etiology, and, among atopic individuals, is exacerbated by documented, but rare, cases of allergic reactions to COVID-19 vaccines.1 –3 Furthermore, conflicting information regarding the safety of COVID-19 vaccines may have caused confusion among individuals with history of severe allergies. We performed semi-structured qualitative interviews to better understand how some adults and families managing allergy perceive vaccine me ssaging, and what influences their decisions to be vaccinated.
Source: Annals of Allergy, Asthma and Immunology - August 28, 2023 Category: Allergy & Immunology Authors: Ayel Luis R. Batac, Kaitlyn A. Merrill, Michael A. Golding, Elissa M. Abrams, Philippe B égin, Moshe Ben-Shoshan, Erika Ladouceur, Leslie E. Roos, Vladan Protudjer, Jennifer L.P. Protudjer Tags: Letters Source Type: research

Unique Gut Microbiome Signatures among Adult Patients with Moderate to Severe Atopic Dermatitis in Southern Chinese
This study provides insights into new therapeutic strategies targeting the gut microbiome for AD and evidence for the involvement of the gut-skin axis in AD patients.PMID:37629036 | DOI:10.3390/ijms241612856
Source: Genomics Proteomics ... - August 26, 2023 Category: Genetics & Stem Cells Authors: Yiwei Wang Jinpao Hou Joseph Chi-Ching Tsui Lin Wang Junwei Zhou Un Kei Chan Claudia Jun Yi Lo Pui Ling Kella Siu Steven King Fan Loo Stephen Kwok Wing Tsui Source Type: research