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Cetuximab-induced cutaneous toxicityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The most frequent cutaneous side effect reported in this series was acneiform eruption. The authors observed that all women with acneiform rash had only limited facial involvement, whereas all but one man experienced more widespread lesions of the face, the back and the chest. We found no association between the extent and severity of cutaneous eruptions (grade 1 vs. grade 2) and patients' response to therapy. (Source: Journal of the European Academy of Dermatology and Venereology)
Source: Journal of the European Academy of Dermatology and Venereology - November 19, 2009 Category: Dermatology Authors: H Tomková, M Kohoutek, M Zábojníková, M Pospí[scaron]ková, L Ostřížková, M Gharibyar Source Type: journals

Effective Desensitization to Imiglucerase in a Patient with Type I Gaucher DiseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a child who had anaphylactic hypersensitivity to imiglucerase therapy for Gaucher disease. Treatment was stopped and symptoms returned. After immune desensitization to imiglucerase using a rush protocol, the patient was able to resume treatment and has not had further hypersensitivity complications to date. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Diego G. Peroni, Lydia Pescollderungg, Giorgio L. Piacentini, Walburga Cassar, Attilio L. Boner Tags: Clinical and Laboratory Observations Source Type: journals

Genzyme Products, Marketed as Cerezyme, Fabrayzme, Myozyme, Aldurazyme, and ThyrogenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Foreign particle contamination of several products manufactured by Genzyme, which may lead to serious adverse events including damage to blood vessels or embolic events, and anaphylactic, allergic and immune-mediated reactions. (Source: FDA MedWatch)
Source: FDA MedWatch - November 13, 2009 Category: American Health Source Type: organizations

Galectin-9 Is a High Affinity IgE-binding Lectin with Anti-allergic Effect by Blocking IgE-Antigen Complex Formation [Glycobiology and Extracellular Matrices]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Galectin (Gal)-9 was first described as an eosinophil chemoattractant. With the progress in research, Gal-9 has come to be known as a versatile immunomodulator that is involved in various aspects of immune regulations, and the entire picture of the function still remains elusive. To uncover as-yet unknown activity of Gal-9, we have been examining the effect of the protein in various disease animal models. Here we show that Gal-9 attenuated asthmatic reaction in guinea pigs and suppressed passive-cutaneous anaphylaxis in mice. These results indicate the mast cell stabilizing effect of Gal-9. In vitro studies of mast cell de...
Source: Journal of Biological Chemistry - November 13, 2009 Category: Chemistry Authors: Niki, T., Tsutsui, S., Hirose, S., Aradono, S., Sugimoto, Y., Takeshita, K., Nishi, N., Hirashima, M. Tags: Glycobiology and Extracellular Matrices Source Type: journals

State of the art and new horizons in the diagnosis and management of egg allergyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Egg allergy is one of the most frequent food allergies in children below the age of three. Common symptoms of egg allergy involve frequently the skin as well as the gut and in more severe cases result in anaphylaxis. Non-IgE-mediated symptoms such as in eosinophilic diseases of the gut or egg-induced enterocolitis might also be observed. Sensitization to egg white proteins can be found in young children in absence of clinical symptoms. The diagnosis of egg allergy is based on the history, IgE tests as well as standardized food challenges. Ovomucoid is the major allergen of egg, and recent advances in technology have improv...
Source: Allergy - November 13, 2009 Category: Allergy & Immunology Authors: A. H. Benhamou, J.-C. Caubet, P. A. Eigenmann, A. Nowak-Węgrzyn, C. P. Marcos, M. Reche, A. Urisu Source Type: journals

Ampicillin: Anaphylaxis in a patient with indolent systemic mastocytosis: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - November 11, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Omeprazole/soya oil emulsion: Anaphylaxis: 2 case reportsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - November 11, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

ACAAI: EMS Teams Vary on Epinephrine Policies (CME/CE, with video)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
MIAMI BEACH (MedPage Today) -- All 50 states allow emergency medical services (EMS) teams to carry epinephrine for anaphylaxis patients, but about a third don't require responders to carry the drug, researchers said here. (Source: MedPage Today Allergy)
Source: MedPage Today Allergy - November 11, 2009 Category: Allergy & Immunology Source Type: news

Allergy skin testing in predicting adverse reactions to fluorescein: a prospective clinical studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The vast majority of adverse reactions to fluorescein are mild and not attributed to immunological mechanisms. Allergy skin tests cannot predict non-immunological reactions but their utility remains substantial in predicting anaphylaxis during SFAs and must be performed in patients reporting risk factors in their past medical history. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 11, 2009 Category: Opthalmology Authors: Dimitrios C. Kalogeromitros, Michael P. Makris, Xenophon S. Aggelides, Anagnostis I. Mellios, Fani C. Giannoula, Kyriaki A. Sideri, Alexander A. Rouvas, Panagiotis G. Theodossiadis Source Type: journals

ACAAI: Gelatin a Culprit in Some Vaccine Reactions (CME/CE)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
MIAMI BEACH (MedPage Today) -- Patients who have anaphylactic reactions to certain vaccines may be allergic to gelatin, researchers say. (Source: MedPage Today Allergy)
Source: MedPage Today Allergy - November 9, 2009 Category: Allergy & Immunology Source Type: news

Dangerous Anaphylaxis Waiting GameEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
More than 40% of people suffering a potentially life-threatening episode of anaphylaxis wait before seeking medical attention, according to a new study. (Source: WebMD Health)
Source: WebMD Health - November 9, 2009 Category: Consumer Health News Source Type: news

Desensitization of ovalbumin-sensitized mice by repeated co-administrations of di-(2-ethylhexyl) phthalate and ovalbumin.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Data from humane and murine studies suggest that DEHP may attenuate the allergic response. More studies are necessary in order to assess the size of this effect and to rule out the underlying mechanism. (Source: BMC Research Notes)
Source: BMC Research Notes - November 9, 2009 Category: Research Authors: Soren LarsenGunnar Nielsen Source Type: journals

ACAAI: EMS Personnel May Not Carry EpinephrineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The availability and use of epinephrine for anaphylaxis by emergency medical services varies nationwide, and less than one-third of anaphylaxis patients prescribed self-injectable epinephrine use it prior to arrival at a hospital, according to research presented at the annual meeting of the American College of Allergy, Asthma & Immunology, held from Nov. 5 to 10 in Miami Beach, Fla. (Source: Modern Medicine)
Source: Modern Medicine - November 9, 2009 Category: Journals (General) Source Type: info

Rash associated with the use of pegylated filgrastim in a patient with advanced pancreatic cancer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a patient with pancreatic cancer who developed facial rash related to the use of pegfilgrastim that led to discontinuation of the agent and we review the literature on this topic. PMID: 19888888 [PubMed - in process] (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - November 6, 2009 Category: Toxicology Authors: Bustillo I, Kaley K, Saif MW Tags: Cutan Ocul Toxicol Source Type: journals

Elevation of alanine transaminase and gallbladder wall abnormalities as biomarkers of anaphylaxis in canine hypersensitivity patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The purpose of the study was to evaluate alanine transaminase (ALT) and gallbladder wall abnormalities as possible biomarkers for anaphylaxis in dogs presented for acute hypersensitivity reactions. Pilot study. A private practice, small animal, 24-hour emergency and specialty hospital. Ninety-six dogs presenting 101 times on an emergency basis for hypersensitivity reactions from March 2007 through March 2009. Veterinarians acquired a history, physical exam, serum chemistry panel, blood pressure, and ultrasound image of the gallbladder. Dogs were then divided into 2 groups: dogs fulfilling the definition for anaphylaxis (mo...
Source: Journal of Veterinary Emergency and Critical Care - November 6, 2009 Category: Veterinary Research Authors: Jonnie E. Quantz, Macon S. Miles, Ann L. Reed, George A. White Source Type: journals

First case report of anaphylaxis to spirulin: identification of phycocyanin as responsible allergenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Allergy)
Source: Allergy - November 4, 2009 Category: Allergy & Immunology Authors: M. Petrus, R. Culerrier, M. Campistron, A. Barre, P. Rougé Source Type: journals

Detection of specific IgE antibodies to cefotiam-HSA conjugate by ELISA in a nurse with occupational anaphylaxisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Allergy)
Source: Allergy - November 3, 2009 Category: Allergy & Immunology Authors: J.-E. Kim, S.-H. Kim, G.-S. Choi, Y.-M. Ye, H.-S. Park Source Type: journals

Hypersensitivity and oral tolerance in the absence of a secretory immune systemEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Compensatory regulatory T-cell function becomes critical in pIgR-deficient mice to avoid the potentially catastrophic effects of systemic immune hyperreactivity, presumably resulting from defective secretory antibody-mediated immune exclusion of microbial components. (Source: Allergy)
Source: Allergy - November 3, 2009 Category: Allergy & Immunology Authors: M. R. Karlsson, F.-E. Johansen, H. Kahu, A. Macpherson, P. Brandtzaeg Source Type: journals

Evolution of iv iron compounds over the last centuryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Administration of intravenous (IV) iron has become pivotal in the management of anaemia in patients with chronic kidney disease (CKD). Since parenteral iron was first introduced for human use in the 1930s, things have come a long way. Seventy years ago, iron was toxic, administered as an iron oxyhydroxide complex. This problem was circumvented with the introduction of compounds containing iron in a core surrounded by a carbohydrate shell. The carbohydrate shell consists of molecules such as dextran, sucrose, dextrin or gluconate. The first dextran-containing IV iron preparations carried a small risk of anaphylaxis, but the...
Source: Journal of Renal Care - November 3, 2009 Category: Urology & Nephrology Authors: Iain C Macdougall Tags: ARTICLES Source Type: journals

A child with anaphylaxis to grapes without reaction to grape seed oilEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Allergy)
Source: Allergy - November 2, 2009 Category: Allergy & Immunology Authors: F. Cardinale, M. Berardi, I. Chinellato, E. Damiani, E. Nettis Source Type: journals

Maternal peanut exposure during pregnancy and lactation reduces peanut allergy risk in offspringEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: We show for the first time maternal transmission of susceptibility to first-exposure peanut reactions and active peanut sensitization. Low-dose peanut exposure during pregnancy and lactation reduced this risk. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - November 1, 2009 Category: Allergy & Immunology Authors: Iván López-Expósito, Ying Song, Kirsi M. Järvinen, Kamal Srivastava, Xiu-Min Li Tags: Food, drug, insect sting allergy, and anaphylaxis Source Type: journals

Predictors of severe systemic anaphylactic reactions in patients with Hymenoptera venom allergy: Importance of baseline serum tryptase—a study of the European Academy of Allergology and Clinical Immunology Interest Group on Insect Venom HypersensitivityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: In patients with honeybee or vespid venom allergy, baseline serum tryptase concentrations are associated with the risk for severe anaphylactic reactions. Preventive measures should include substitution of angiotensin-converting enzyme inhibitors. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - November 1, 2009 Category: Allergy & Immunology Authors: Franziska Ruëff, Bernhard Przybilla, Maria Beatrice Biló, Ulrich Müller, Fabian Scheipl, Werner Aberer, Joëlle Birnbaum, Anna Bodzenta-Lukaszyk, Floriano Bonifazi, Christoph Bucher, Paolo Campi, Ulf Darsow, Cornelia Egger, Gabrielle Haeberli, Thomas H Tags: Food, drug, insect sting allergy, and anaphylaxis Source Type: journals

Mutation of tyrosine 145 of lymphocyte cytosolic protein 2 protects mice from anaphylaxis and arthritisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Our data indicate that Y145 is the most critical tyrosine supporting SLP-76 function in myeloid cells. Future efforts to dissect how Y145 mediates SLP-76–dependent signaling in MCs and PMNs will increase our understanding of these lineages and provide insights into the treatment of allergy and inflammation. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - November 1, 2009 Category: Allergy & Immunology Authors: Laurie E. Lenox, Taku Kambayashi, Mariko Okumura, Christopher Prieto, Karsten Sauer, Ralph M. Bunte, Martha S. Jordan, Gary A. Koretzky, Kim E. Nichols Tags: Mechanisms of allergy and clinical immunology Source Type: journals

Bed bugs - What the GP needs to know.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article reviews the various clinical consequences of bed bug bites and outlines management strategies. DISCUSSION: Common dermatological responses include the early development of small macular spots that may later progress into prominent wheals accompanied by intense itching. Patients exposed to numerous bed bugs can present with a widespread erythematous rash or urticaria. Bullous eruptions are not uncommon and anaphylaxis has been reported, albeit rarely. There is no evidence that bed bugs transmit human pathogens, but they are responsible for significant psychological distress, can produce anaemia when abundant, a...
Source: Australian Family Physician - November 1, 2009 Category: Primary Care Authors: Doggett SL, Russell R Tags: Aust Fam Physician Source Type: journals

Methylprednisolone succinate: Anaphylaxis: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - October 31, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Protamine sulfate: Anaphylaxis: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - October 31, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Chlorhexidine urticaria: A rare occurrence with a common mouthwashEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sharma Anamika, Chopra HarneetIndian Journal of Dental Research 2009 20(3):377-379Chlorhexidine is a widely used antiseptic and disinfectant in medical and nonmedical environments. Compared to its ubiquitous use, allergic contact dermatitis from chlorhexidine has rarely been reported and so its sensitization rate seems to be low. The prevalence of contact urticaria and anaphylaxis due to chlorhexidine remains to be unknown. This case report presents a case of urticaria due to oral use of chlorhexidine. The adverse reaction was confirmed by skin prick test. (Source: Table of Contents : Indian Journal of Dental Research : 2006 - 17(3))
Source: Table of Contents : Indian Journal of Dental Research : 2006 - 17(3) - October 31, 2009 Category: Dentistry Authors: Sharma Anamika, Chopra Harneet Source Type: journals

Anaphylaxis to mango fruit and crossreactivity with Artemisia vulgaris pollen.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19862948 [PubMed - in process] (Source: Journal of Investigational Allergology & Clinical Immunology)
Source: Journal of Investigational Allergology & Clinical Immunology - October 31, 2009 Category: Allergy & Immunology Authors: Silva R, Lopes C, Castro E, Ferraz de Oliveira J, Bartolomé B, Castel-Branco MG Tags: J Investig Allergol Clin Immunol Source Type: journals

First successful puncture, aspiration, injection, and re-aspiration of hydatid cyst in the liver presenting with anaphylactic shock in Korea.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hydatid disease is a parasitic infestation caused by the larval form of Echinocococcus. In human, the most commonly affected organs are liver and lung. Most cysts remain clinically silent and are diagnosed incidentally or when complications occur. In Korea, hydatid disease is rare and surgically treated cases have been reported in the Korean literature. However, it is expected to confront this disease sooner or later, because of recent increase in traveling to the endemic area and industrial workers originating from those areas. With this trend, we experienced a case of hydatid cyst of the liver in a male patient from ...
Source: Yonsei Medical Journal - October 31, 2009 Category: Universities & Medical Training Authors: Park KH, Jung SI, Jang HC, Shin JH Tags: Yonsei Med J Source Type: journals

When yellow jackets attack: Recurrent and severe anaphylactic reactions to insect bites and stingsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No abstract. (Source: American Journal of Hematology)
Source: American Journal of Hematology - October 28, 2009 Category: Hematology Authors: Daniel A. Pollyea, Tracy I. George, Christopher Corless, Jason Gotlib Source Type: journals

Peanut varieties with reduced Ara h 1 content indicating no reduced allergenicityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Peanut allergy is a major cause of food-induced severe anaphylactic reactions. To date, no medical care is available to prevent and treat peanut allergy and therefore hypoallergenic peanut varieties are of considerable health political and economic interest. Major allergens that induce IgE-responses in peanut-sensitive patients are Ara h 1, Ara h 2 and Ara h 3/4. In order to identify hypoallergenic peanuts, commercially locally available peanut varieties were screened for their allergen content. Ara h 1-deficient peanuts from Southeast Asia were identified by SDS-PAGE, immunoblotting, inhibition assays and ELISA. 2-D PAGE ...
Source: Molecular Nutrition - October 28, 2009 Category: Nutrition Authors: Susanne Krause, Ties Latendorf, Hendrik Schmidt, Yasemin Darcan-Nicolaisen, Gerald Reese, Arnd Petersen, Ottmar Janssen, Wolf-Meinhard Becker Source Type: journals

Vinegar decreases allergenic response in lentil and egg food allergy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Vinegar addition during the cooking process may decrease lentil and chicken allergenicity. PMID: 19879037 [PubMed - as supplied by publisher] (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - October 28, 2009 Category: Allergy & Immunology Authors: Armentia A, Dueñas-Laita A, Pineda F, Herrero M, Martín B Tags: Allergol Immunopathol (Madr) Source Type: journals

Food-dependent exercise-induced anaphylaxis in the celery-mugwort-birch-spice syndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Allergy)
Source: Allergy - October 27, 2009 Category: Allergy & Immunology Authors: C.-H. Baek, Y.-J. Bae, Y. S. Cho, H.-B. Moon, T.-B. Kim Source Type: journals

Dexferrum: labelling changes over anaphylactic-type reactionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - October 26, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Cobalin-H injection (Hydroxycobalamin) - Revised SPCEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: eMC (electronic Medicines Compendium) Area: Other Library Updates > SPC Changes Section 4.8 has been changed from: Allergic hypersensitivity reactions have occurred rarely following the administration of hydroxocobalamin And is now as follows: The following effects have been reported and are listed below by body system: Disorders of the immune system: Rare: Allergic hypersensitivity reactions Very Rare: Anaphylaxis Gastro intestinal disorders: Frequency Not Known: Nausea General disorders: Frequency Not Known: Fever, dizziness, Injection site disorders Neurological disorders: ...
Source: NeLM - Haematology - October 26, 2009 Category: Hematology Source Type: organizations

Anaphylaxis and Anesthesia: Controversies and New InsightsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Anaphylaxis may be a life-threatening clinical condition and is likely a result of drugs or substances used for anesthesia or surgery. The criteria for the diagnosis and clinical treatment are discussed. (Source: Anesthesiology)
Source: Anesthesiology - October 24, 2009 Category: Anesthesiology Tags: Clinical Concepts and Commentary Source Type: journals

Dexferrum labeling change warns of possible anaphylactic-type reactions [News and Features]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: AAP News)
Source: AAP News - October 22, 2009 Category: Pediatrics Tags: News and Features Source Type: journals

Effect of Oral Sodium Cromoglycate in 2 Children With Food-Dependent Exercise-Induced Anaphylaxis (FDEIA)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Our findings suggest that SCG prevents FDEIA caused by wheat allergy. (Source: Clinical Pediatrics)
Source: Clinical Pediatrics - October 19, 2009 Category: Pediatrics Authors: Sugimura, T., Tananari, Y., Ozaki, Y., Maeno, Y., Ito, S., Yoshimoto, Y., Kawano, K., Tanaka, S. Tags: Articles Source Type: journals

The food allergy in medical practiceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The food protein triggering the allergic response is termed a food allergen. Six to eight percent of children under the age of three have food allergies and nearly four percent of adults have them. The most common food allergies in adults are shellfish, peanuts, tree nuts, fish, and eggsand the most common food allergies in children are milk, eggs, peanuts, and tree nus. Conditions caused by food allergies are classified into 3 groups according to the mechanism of the allergic response. The reaction may progress to anaphylactic shock: a systemic reaction involving several different bodily systems including hypotension (low...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Anaphylaxis in childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Anaphylaxis, though rare, is an increasing emergency especially in children and remains under-diagnosed and undertreated. Boys outnumber girls by 3 : 2 in preschool children, but from the age of 15 females predominate. Food is the main trigger of anaphylaxis in children with the commonest being nuts and milk. The diagnosis is primarily based on the clinical history and clinical criteria. The most to less frequent symptoms concern dermatological, respiratory, gastrointestinal and cardiovascular ones, respectively. Emergency management requires the life support ABCDE approach. Intramuscular adrenalin, repeated as required, i...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Immunotherapy in adults and seniors – clinical aspectsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Specific allergen immunotherapy (SIT) is a broadly used and highly effective therapeutic method of treating respiratory allergies and insect venom allergy (venom immunotherapy – VIT). Specific allergen immunotherapy is generally recommended for adults > 60, but the age criterion does not apply to VIT since venom allergy is a life-threatening condition. The frequency of the occurrence of anaphylactic events during SIT is comparable in both groups of younger and older patients, but if the events do occur, they tend to be more severe in the latter group. The higher risk of a severe anaphylactic reaction occurring in old...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Food-related asthma – proEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Some foods are capable of provoking asthmatic symptoms. In over 8% of children, the aetiology of asthma was food-related. Children admitted to intensive care were significantly more likely to report food allergy (FA) – 7 times more at least one FA compared with children seen in the ambulatory setting. The association was stronger among children with multiple or severe FA. Children with FA developed asthma earlier and at higher prevalence. Asthma mortality in children and young adults: FA and inadequate treatment were the major risk factors. An alarming finding was that 11 of the 37 deaths were probably caused by FA. ...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Cefazolin: Fatal anaphylaxis: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - October 19, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Fentanyl: Anaphylactic reaction following transdermal administration: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - October 19, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Triamcinolone: Anaphylaxis following intra-articular administration: 2 case reportsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - October 19, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

FDA notification of labelling change for iron dextran injection (Dexferrum®) following reports of anaphylaxisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: FDA Area: News The FDA has issued a notification about a labelling change for iron dextran injection (Dexferrum®) following reports of anaphylactic-type reactions, including fatalities after the parenteral administration of iron dextran injection (Dexferrum®). The Boxed Warning has been modified to recommend administering a test dose prior to the first therapeutic dose and observing for signs or symptoms of anaphylactic-type reactions during drug administration. Fatal reactions have even occurred even when the test dose was tolerated. Patients with a history of drug allergy or multiple drug allergies may be at i...
Source: NeLM - Immunology and vaccination - October 18, 2009 Category: Allergy & Immunology Source Type: organizations

Test Dose, Observation Recommended for Iron Dextran AdministrationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Anaphylactic reactions, including fatalities, have been reported after parenteral administration of iron dextran injection. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 16, 2009 Category: Consumer Health News Tags: Public Health & Prevention Source Type: news

Dexferrum (iron dextran injection) - Labeling ChangeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Risk of anaphylactic-type reactions, including fatalities, have followed the parenteral administration of iron dextran injection. (Source: FDA MedWatch)
Source: FDA MedWatch - October 16, 2009 Category: American Health Source Type: organizations

Dexferrum (iron dextran injection) - Labeling ChangeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Audience: Hematological healthcare professionals, hospital risk managers American Regent and FDA notified healthcare professionals that anaphylactic-type reactions, including fatalities, have followed the parenteral administration of iron... (Source: Drugs.com - FDA MedWatch Alerts)
Source: Drugs.com - FDA MedWatch Alerts - October 16, 2009 Category: Drugs & Pharmacology Source Type: news