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29251 records returned

Treatment of Metastatic Spinal Tumors by Percutaneous Vertebroplasty versus Percutaneous Vertebroplasty Combined with Interstitial Implantation of (125)I Seeds.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: PVP is a minimally invasive procedure with small wounds and minor complications. It is effective in the alleviation of pain in metastatic spinal tumor patients, and its clinical outcomes can be enhanced by the combination of interstitial implantation of (125)I seeds. PMID: 19922311 [PubMed - as supplied by publisher] (Source: Acta Radiologica)
Source: Acta Radiologica - November 21, 2009 Category: Radiology Authors: Yang Z, Yang D, Xie L, Sun Y, Huang Y, Sun H, Liu P, Wu Z Tags: Acta Radiol Source Type: journals

Anesthetic spray shows promise for premature ejaculationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The first U.S. trials of a spray-on anesthetic for the penis showed that it increased the time to ejaculation nearly fivefold, providing the first good solution for premature ejaculation, researchers reported Thursday. (Source: L.A. Times - Health)
Source: L.A. Times - Health - November 21, 2009 Category: Consumer Health News Source Type: news

[Clinical and therapeutic heterogeneity of cerebral venous thrombosis: a description of a series of 20 cases.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS. We report a great variety of etiologies and patterns of presentation of CVT. CVT should be suspected in patients with subacute headache, even in outpatients. Nonacute presentation with isolated headache or intracranial hypertension could have better prognosis, requiring a less aggressive therapy. PMID: 19921621 [PubMed - as supplied by publisher] (Source: Revista de Neurologia)
Source: Revista de Neurologia - November 21, 2009 Category: Neurology Authors: Flores-Barragan JM, Hernandez-Gonzalez A, Gallardo-Alcaniz MJ, Del Real-Francia MA, Vaamonde-Gamo J Tags: Rev Neurol Source Type: journals

Renal dopaminergic defect in C57Bl/6J miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The C57Bl/6J mouse strain, the genetic background of many transgenic and gene knockout models, is salt sensitive and resistant to renal injury. We tested the hypothesis that renal dopaminergic function is defective in C57Bl/6J mice. On normal NaCl (0.8%, 1 wk) diet, anesthetized and conscious (telemetry) blood pressures were similar in C57Bl/6J and SJL/J mice. High NaCl (6%, 1 wk) increased blood pressure (30%) in C57Bl/6J but not in SJL/J mice and urinary dopamine to greater extent in SJL/J than in C57Bl/6J mice. Absolute and fractional sodium excretions were lower in SJL/J than in C57Bl/6J mice. The blood pressure-natriu...
Source: AJP: Regulatory, Integrative and Comparative Physiology - November 20, 2009 Category: Physiology Authors: Escano, C. S., Armando, I., Wang, X., Asico, L. D., Pascua, A., Yang, Y., Wang, Z., Lau, Y.-S., Jose, P. A. Tags: Articles Source Type: journals

Harmful effects seen with repeated ketamine abuseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
NEW YORK (Reuters Health) - Abuse of ketamine, a powerful anesthetic, is on the rise in many countries and now new research shows that repeated use of the club drug impairs memory, concentration, and psychological well-being. (Source: Reuters: Health)
Source: Reuters: Health - November 20, 2009 Category: Consumer Health News Tags: healthNews Source Type: news

Percutaneous Intervention of the C2 Vertebral Body Using a CT-Guided Posterolateral ApproachEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION. The CT-guided posterolateral approach was safe, feasible, and effective for percutaneous intervention of the C2 vertebral body. (Source: American Journal of Roentgenology)
Source: American Journal of Roentgenology - November 20, 2009 Category: Radiology Authors: Sun, H. Y., Lee, J. W., Kim, K.-J., Yeom, J. S., Kang, H. S. Tags: Vascular and Interventional Radiology Source Type: journals

Comparison of morphine concentration-time profiles following intravenous and intranasal diamorphine in childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Our evidence supports the wider use of diamorphine administration by nasal drops in children, as it shows that adequate plasma levels of morphine are usually achieved. However, we demonstrated significantly attenuated and delayed peak plasma morphine levels with lower levels at 1 h with intranasal compared with intravenous diamorphine. (Source: Archives of Disease in Childhood)
Source: Archives of Disease in Childhood - November 20, 2009 Category: Pediatrics Authors: Kidd, S, Brennan, S, Stephen, R, Minns, R, Beattie, T Tags: Immunology (including allergy), Pain (neurology), Pain (palliative care), Pain (anaesthesia) Drug therapy Source Type: journals

Intranasal diamorphine for acute sickle cell painEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The painful crisis is the commonest acute presentation of sickle cell disease (SCD), yet effective pain control in hospital is often delayed, inadequate and dependent on injected opiates. Intranasal diamorphine (IND) has been used in paediatric emergency departments for management of acute pain associated with fractures, but the analgesic effect is short lived. We evaluated its efficacy and safety when given in combination with intravenous or oral morphine for rapid analgesia for children presenting to our emergency department with painful crisis of SCD. In phase 1, nine patients received IND plus intravenous morphine. In ...
Source: Archives of Disease in Childhood - November 20, 2009 Category: Pediatrics Authors: Telfer, P, Criddle, J, Sandell, J, Davies, F, Morrison, I, Challands, J Tags: Pain (neurology), Pain (palliative care), Pain (anaesthesia) Drug therapy Source Type: journals

Proliferation and differentiation of periodontal ligament cells following short-term tooth movement in the rat using different regimens of loadingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study aimed to further analyse this regulatory process experimentally in the rat. The right upper first molars of 25 twelve-week-old male Wistar anaesthetized rats were loaded with forces in order to be moved mesially. Constant forces for 4 hours of 0.25 and 0.5 N were applied in five animals each. Furthermore, constant forces for 2 hours of 0.1 N were applied in 10 animals and afterwards, the first and second molars were permanently separated with composite. In these animals, the antagonists were sliced and five rats were killed after 1 day and five after 2 days. As a last experiment, intermittent forces of 0.1 N and...
Source: The European Journal of Orthodontics - November 20, 2009 Category: Dentistry Authors: Pavlidis, D., Bourauel, C., Rahimi, A., Gotz, W., Jager, A. Tags: Articles Source Type: journals

The Next Generation of Colloids: Ready for "Prime Time"?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19923493 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Nussmeier NA, Searles BE Tags: anesth Analg Source Type: journals

Intravenous Lidocaine for Ambulatory Anesthesia: Good to Go or Not So Fast?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19923494 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Wu CL, Liu SS Tags: anesth Analg Source Type: journals

Difficult Mask Ventilation: What Needs Improvement?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19923495 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Salem MR, Ovassapian A Tags: anesth Analg Source Type: journals

The Ultimate Difficult Airway: Minimizing Emergency Surgical Access.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19923496 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Fisher QA Tags: anesth Analg Source Type: journals

Intracranial Pressure, Brain Vessels, and Consciousness Recovery in Traumatic Brain Injury.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19923497 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Stocchetti N Tags: anesth Analg Source Type: journals

CON: Temperature Regimens and Neuroprotection During Cardiopulmonary Bypass: Does Rewarming Rate Matter?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19923498 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Cook DJ Tags: anesth Analg Source Type: journals

PRO: Temperature Regimens and Neuroprotection During Cardiopulmonary Bypass: Does Rewarming Rate Matter?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19923499 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Grocott HP Tags: anesth Analg Source Type: journals

A Core Review of Temperature Regimens and Neuroprotection During Cardiopulmonary Bypass: Does Rewarming Rate Matter?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Despite a half century of research and the implementation of various risk-reduction strategies among clinicians and basic scientists, patients continue to experience strokes and cognitive dysfunction related to the use of cardiopulmonary bypass (CPB) for cardiac surgery. One strategy to reduce these detrimental effects has been the use of hypothermia. Although numerous studies have addressed the issue, the question of whether the use of hypothermia during CPB attenuates the impact of central nervous system consequences remains unresolved. However, data clearly demonstrate that hyperthermia is to be avoided in the perio...
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Grigore AM, Murray CF, Ramakrishna H, Djaiani G Tags: anesth Analg Source Type: journals

Cardiopulmonary Bypass Priming Using a High Dose of a Balanced Hydroxyethyl Starch Versus an Albumin-Based Priming Strategy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: High-volume priming of the CPB circuit with a modern balanced HES solution resulted in reduced inflammation, less endothelial damage, and fewer alterations in renal tubular integrity compared with an albumin-based priming. Coagulation including platelet function was better preserved with high-dose balanced HES CPB priming compared with albumin-based CPB priming. PMID: 19923501 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Boldt J, Suttner S, Brosch C, Lehmann A, Röhm K, Mengistu A Tags: anesth Analg Source Type: journals

Radial Artery Cannulation: A Comprehensive Review of Recent Anatomic and Physiologic Investigations.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Consistent anatomic accessibility, ease of cannulation, and a low rate of complications have made the radial artery the preferred site for arterial cannulation. Radial artery catheterization is a relatively safe procedure with an incidence of permanent ischemic complications of 0.09%. Although its anatomy in the forearm and the hand is variable, adequate collateral flow in the event of radial artery thrombosis is present in most patients. Harvesting of the radial artery as a conduit for coronary artery bypass grafting, advances in plastic and reconstructive surgery of the hand, and its use as an entry site for cardiac ...
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Brzezinski M, Luisetti T, London MJ Tags: anesth Analg Source Type: journals

Cardiac Anesthesia: Thirty Years Later--The Second Annual Arthur E. Weyman Lecture.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cardiac anesthesiology has evolved spectacularly over the past 30 yr, changing from a practice focused on the anesthetic management of patients with cardiovascular diseases to a practice of cardiovascular medicine that contributes to the medical and surgical management of cardiovascular patients. The second Weyman lecture reviews this history, the critical role of the Society of Cardiovascular Anesthesiologists in the evolution of the specialty, and the prospects for continued development for the specialty, the society, and the patients they care for. PMID: 19923503 [PubMed - as supplied by publisher] (Source: Anes...
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Thys DM Tags: anesth Analg Source Type: journals

Defining the Reliability of Sonoanatomy Identification by Novices in Ultrasound-Guided Pediatric Ilioinguinal and Iliohypogastric Nerve Blockade.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: We have demonstrated that although there is no difference in the overall accuracy of muscle plane versus II/IH nerve identification, the muscle planes are reliably identified after fewer scans of the inguinal region. We suggest that a reliable end point for the inexperienced practitioner of ultrasound-guided II/IH nerve block may be the TA/internal oblique plane where the nerves are reported to be found in 100% of cases. PMID: 19923504 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Ford S, Dosani M, Robinson AJ, Campbell GC, Ansermino JM, Lim J, Lauder GR Tags: anesth Analg Source Type: journals

Incisional Continuous Fascia Iliaca Block Provides More Effective Pain Relief and Fewer Side Effects than Opioids After Pelvic Osteotomy in Children.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Continuous incisional FIC block provides excellent postoperative pain relief, less sedation, and better return of appetite than morphine IV after pelvic osteotomy in children. PMID: 19923505 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Lako SJ, Steegers MA, van Egmond J, Gardeniers J, Staals LM, van Geffen GJ Tags: anesth Analg Source Type: journals

Systemic Lidocaine Decreased the Perioperative Opioid Analgesic Requirements but Failed to Reduce Discharge Time After Ambulatory Surgery.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Perioperative systemic lidocaine significantly reduces opioid requirements in the ambulatory setting without affecting time to discharge. PMID: 19923506 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: McKay A, Gottschalk A, Ploppa A, Durieux ME, Groves DS Tags: anesth Analg Source Type: journals

The Correlation Between Bispectral Index and Observational Sedation Scale in Volunteers Sedated with Dexmedetomidine and Propofol.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The combination of both BIS and sedative scales could provide different and complementary data to the clinician evaluating the patient's response to sedation than would either tool alone, especially when dexmedetomidine is used. PMID: 19923507 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Kasuya Y, Govinda R, Rauch S, Mascha EJ, Sessler DI, Turan A Tags: anesth Analg Source Type: journals

Gamma-Aminobutyric Acid Type A Receptor Alpha 4 Subunit Knockout Mice Are Resistant to the Amnestic Effect of Isoflurane.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: These results lend support to the hypothesis that different sites of action mediate different anesthetic end points and suggest that alpha4-containing GABA(A)-Rs are important mediators of the amnestic effect of isoflurane on hippocampal-dependent declarative memory. PMID: 19923508 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Rau V, Iyer SV, Oh I, Chandra D, Harrison N, Eger EI, Fanselow MS, Homanics GE, Sonner JM Tags: anesth Analg Source Type: journals

Stroke Volume Variation During Acute Normovolemic Hemodilution.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The SVV derived from the FloTrac/Vigileo system changes significantly as blood is removed and replaced during hemodilution. These changes correlate with 3D TEE measurements of LV volume. The utility of SVV in guiding optimization of intravascular volume merits further study. PMID: 19923509 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Kungys G, Rose DD, Fleming NW Tags: anesth Analg Source Type: journals

A Comparison of Micropore Membrane Inlet Mass Spectrometry-Derived Pulmonary Shunt Measurement with Riley Shunt in a Porcine Model.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Shunt derived from MMIMS inert gas retention data correlated well with R-S during breathing of oxygen. Shunt as derived by MMIMS was generally less than R-S. PMID: 19923510 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Duenges B, Vogt A, Bodenstein M, Wang H, Böhme S, Röhrig B, Baumgardner JE, Markstaller K Tags: anesth Analg Source Type: journals

A Visual Stethoscope to Detect the Position of the Tracheal Tube.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: During advancement of the tracheal tube, alterations of the shape of the visualized breath sounds using the Visual Stethoscope appeared before the changes of the breath sounds were detected by auscultation. Bilateral breath sounds disappeared when the tip of the tracheal tube was advanced beyond the carina in both groups. PMID: 19923511 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Kato H, Suzuki A, Nakajima Y, Makino H, Sanjo Y, Nakai T, Shiraishi Y, Katoh T, Sato S Tags: anesth Analg Source Type: journals

Does Patient Position Influence the Reading of the Bispectral Index Monitor?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Changing a patient's position significantly affects the BIS values, which might affect the interpretation of anesthetic depth. PMID: 19923512 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Kaki AM, Almarakbi WA Tags: anesth Analg Source Type: journals

A Comparison of Transmittance and Reflectance Pulse Oximetry During Vascular Surgery.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The new reflectance forehead Spo(2) probe tested has acceptable agreement with the older transmittance probe placed on the earlobe for pulse oximetry within typical ranges of Spo(2) in patients undergoing vascular surgery. PMID: 19923513 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Wax DB, Rubin P, Neustein S Tags: anesth Analg Source Type: journals

Glucose as a Marker of Fluid Absorption in Bipolar Transurethral Surgery.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: In bipolar TURP, the addition of glucose to a concentration of 1% in the electrolyte-containing irrigation fluid can be used as a tracer of absorption that is comparable with measuring serum sodium after monopolar TURP. PMID: 19923514 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Piros D, Fagerström T, Collins JW, Hahn RG Tags: anesth Analg Source Type: journals

The Flex-ItTM Stylet Is Less Effective than a Malleable Stylet for Orotracheal Intubation Using the GlideScope(R).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: In a group of experienced operators using the GlideScope, the FIS was less effective for orotracheal intubation than a malleable endotracheal tube stylet. PMID: 19923515 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Turkstra TP, Jones PM, Ower KM, Gros ML Tags: anesth Analg Source Type: journals

Difficult Mask Ventilation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Mask ventilation is the most fundamental skill in airway management. In this review, we summarize the current knowledge about difficult mask ventilation (DMV) situations. Various definitions for DMV have been used in the literature. The lack of a precise standard definition creates a problem for studies on DMV and causes confusion in data communication and comparisons. DMV develops because of multiple factors that are technique related and/or airway related. Frequently, the pathogenesis involves a combination of these factors interacting to cause the final clinical picture. The reported incidence of DMV varies widely (...
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: El-Orbany M, Woehlck HJ Tags: anesth Analg Source Type: journals

A New Index Derived from the Cerebrovascular Pressure Transmission and Correlated with Consciousness Recovery in Severely Head-Injured Intensive Care Patients.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Gr/Gc, which characterizes the cerebrovascular transmission, better discriminates bad evolution than high values of ICP or low values of cerebral perfusion pressure in patients with severe head trauma. A reduction in Gr/Gc ratio might be an early alarm signaling worsening intracranial hemodynamic conditions. PMID: 19923517 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Roustan JP, Neveu D, Falquet Y, Barral L, Chardon P, Capdevila X Tags: anesth Analg Source Type: journals

The Impact of Spontaneous Ventilation on Distribution of Lung Aeration in Patients with Acute Respiratory Distress Syndrome: Airway Pressure Release Ventilation Versus Pressure Support Ventilation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Spontaneous ventilation during APRV improves lung aeration by decreasing atelectasis. PSV for gas exchange is effective but not sufficient to improve lung aeration. These results indicate that APRV is more efficient than PSV as a mode of primary ventilatory support to decrease atelectasis in patients with ARDS. PMID: 19923518 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Yoshida T, Rinka H, Kaji A, Yoshimoto A, Arimoto H, Miyaichi T, Kan M Tags: anesth Analg Source Type: journals

Airway Injury During Emergency Transcutaneous Airway Access: A Comparison at Cricothyroid and Tracheal Sites.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Airway injury and luminal compression were more common at the tracheal site than at the CTM. The ST and TT were associated with the highest incidence of injury. This has implications for emergency airway access in cases in which it may be difficult to accurately identify the CTM. PMID: 19923519 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Salah N, El Saigh I, Hayes N, McCaul C Tags: anesth Analg Source Type: journals

Recombinant Activated Factor VII in Obstetric Hemorrhage: Experiences from the Australian and New Zealand Haemostasis Registry.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The reported effect of rFVIIa in many, but not all, obstetric cases was positive. There was no mortality as a result of thromboembolic complications. Randomized, controlled trials are required to confirm its safety and efficacy and to assess the possibility that use at an earlier stage in treatment of severe postpartum hemorrhage may avoid the need to resort to postpartum hysterectomy for control of bleeding, thus preserving fertility. PMID: 19923520 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Phillips LE, McLintock C, Pollock W, Gatt S, Popham P, Jankelowitz G, Ogle R, Cameron PA Tags: anesth Analg Source Type: journals

The Effects of Crystalloid and Colloid Preload on Cardiac Output in the Parturient Undergoing Planned Cesarean Delivery Under Spinal Anesthesia: A Randomized Trial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Despite CO and FTc increases after fluid preload, particularly with HES 1.0 L, hypotension still occurred. The data suggest that CO increases after these preload regimens cannot compensate for reductions in arterial blood pressure after spinal anesthesia. PMID: 19923521 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Tamilselvan P, Fernando R, Bray J, Sodhi M, Columb M Tags: anesth Analg Source Type: journals

Systemic Remifentanil for Labor Analgesia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
There is a need for safe, effective, and easy-to-administer systemic analgesia that ideally has rapid onset and offset, matches the time course of uterine contractions, and does not compromise the fetus. Although neuraxial blockade is the "gold standard" for labor analgesia, systemic analgesia is useful in those cases in which neuraxial analgesia is contraindicated, refused or simply not needed by the parturient, or when skilled anesthesia providers are not available. Because of its unique pharmacologic properties, remifentanil has been investigated, and is used clinically, to provide IV labor analgesia. In this focuse...
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Hinova A, Fernando R Tags: anesth Analg Source Type: journals

Clinical Implications of Neuraxial Anesthesia in the Parturient with Scoliosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Scoliosis can pose challenges to the initiation and function of neuraxial anesthetics. We reviewed the available literature exploring neuraxial techniques in parturients with uncorrected or corrected (i.e., surgically instrumented) scoliosis. The 22 articles reported 117 attempted neuraxial procedures (uncorrected n = 24 and corrected n = 93). Of these procedures, 79% of uncorrected patients and 69% of corrected patients were successfully managed with neuraxial anesthesia. Procedures were typically more challenging in corrected patients; 90% of all reported difficulties in this subgroup involved epidural anesthetics. C...
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Ko JY, Leffert LR Tags: anesth Analg Source Type: journals

The Role of 20-Hydroxyeicosatetraenoic Acid in Cerebral Arteriolar Constriction and the Inhibitory Effect of Propofol.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Either neuronal transmission-dependent or exogenous 20-HETE seems to induce cerebral parenchymal arteriolar constriction via superoxide production resulting from NADPH oxidase activation. Propofol is likely to prevent this constriction via inhibition of NADPH oxidase, but not by its scavenging effect on superoxide. PMID: 19923524 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Hama-Tomioka K, Kinoshita H, Azma T, Nakahata K, Matsuda N, Hatakeyama N, Kikuchi H, Hatano Y Tags: anesth Analg Source Type: journals

Nimodipine Prevents Memory Impairment Caused by Nitroglycerin-Induced Hypotension in Adult Mice.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: In a PA retention paradigm, the injection of NTG immediately after learning produced a significant impairment of long-term associative memory in mice, whereas delayed induced hypotension had no effect. NIMO attenuated the disruption in consolidation of long-term memory caused by NTG but did not improve latency in the absence of hypotension. The observed effect of NIMO may have been attributable to the preservation of calcium homeostasis during hypotension, because there were no differences in the PbtO(2) indices among groups. PMID: 19923525 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Bekker A, Haile M, Li YS, Galoyan S, Garcia E, Quartermain D, Kamer A, Blanck T Tags: anesth Analg Source Type: journals

Perioperative Management of the Adult with Cystic Fibrosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Since cystic fibrosis (CF) was first differentiated from celiac disease in 1938, the medical care of patients with CF has substantially improved. These improvements have resulted in a significant increase in median survival and the quality of life experienced by patients. The resultant increase in survival has caused the "average" CF patient to be a young adult and not a child. The gene that causes CF was first identified in 1989 and is the first gene discovered by positional cloning. Unfortunately, gene therapy for CF has not been successful, although it continues to hold great promise for future patient care. Althoug...
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Huffmyer JL, Littlewood KE, Nemergut EC Tags: anesth Analg Source Type: journals

The Early and Delayed Analgesic Effects of Ketamine After Total Hip Arthroplasty: A Prospective, Randomized, Controlled, Double-Blind Study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Ketamine had a morphine-sparing effect after THA, even when morphine was combined with multimodal systemic analgesia. It also facilitated rehabilitation at 1 mo and decreased postoperative chronic pain up to 6 mo after surgery. PMID: 19923527 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Remérand F, Le Tendre C, Baud A, Couvret C, Pourrat X, Favard L, Laffon M, Fusciardi J Tags: anesth Analg Source Type: journals

The Effect of Single-Dose Propofol Injection on Pain and Quality of Life in Chronic Daily Headache: A Randomized, Double-Blind, Controlled Trial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: A single IV infusion of propofol 2.4 mg/kg produces a statistically significant, but not clinically meaningful, reduction in disability from CDH 30 days after infusion and does not reduce pain intensity or analgesic use. This study does not support this regimen of IV propofol for clinical management of CDH. PMID: 19923528 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Simmonds MK, Rashiq S, Sobolev IA, Dick BD, Gray DP, Stewart BJ, Jamieson-Lega KI Tags: anesth Analg Source Type: journals

Improvement in Psychosocial Outcomes in Chronic Pain Patients Receiving Intrathecal Morphine Infusions.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: IT infusion of morphine using an implantable pump was helpful in improving psychosocial function in patients with intractable pain that had failed to respond to standard multimodal analgesic therapy. PMID: 19923529 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Duse G, Davià G, White PF Tags: anesth Analg Source Type: journals

A Transdermal Nicotine Patch Is Not Effective for Postoperative Pain Management in Smokers: A Pilot Dose-Ranging Study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Transdermal nicotine, 5-15 mg, failed to relieve postoperative pain or reduce opioid use in smokers. PMID: 19923530 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Olson LC, Hong D, Conell-Price JS, Cheng S, Flood P Tags: anesth Analg Source Type: journals

Ketoprofen Produces Modality-Specific Inhibition of Pain Behaviors in Rats After Plantar Incision.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: This study demonstrates that ketoprofen is an effective analgesic for nonevoked guarding in rats after plantar incision. There was no effect on mechanical or heat responses, which highlights the importance of multiple-modality testing of pain behaviors for drug evaluation. We found efficacy at doses used clinically in postoperative patients. PMID: 19923531 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Spofford CM, Ashmawi H, Subieta A, Buevich F, Moses A, Baker M, Brennan TJ Tags: anesth Analg Source Type: journals

Early Changes in Homer1 Proteins in the Spinal Dorsal Horn Are Associated with Loose Ligation of the Rat Sciatic Nerve.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The ligation-associated changes in the protein levels of Homer1a and Homer1b/c in the ipsilateral PSD of spinal dorsal horn neurons may be an important early reflection of the injury-associated plasticity that in time leads to the development of persistent pain. PMID: 19923532 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Miletic G, Driver AM, Miyabe-Nishiwaki T, Miletic V Tags: anesth Analg Source Type: journals

Superficial Cervical Plexus Neuropathy After Single-Injection Interscalene Brachial Plexus Block.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Superficial cervical plexus neuropathy is not uncommon after ISB using the modified lateral approach and the possibility should be discussed with patients preprocedurally. PMID: 19923533 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Christ S, Rindfleisch F, Friederich P Tags: anesth Analg Source Type: journals