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841 records returned

Apraxia in progressive nonfluent aphasiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The clinical and neuroanatomical correlates of specific apraxias in neurodegenerative disease are not well understood. Here we addressed this issue in progressive nonfluent aphasia (PNFA), a canonical subtype of frontotemporal lobar degeneration that has been consistently associated with apraxia of speech (AOS) and in some cases orofacial apraxia, limb apraxia and/or parkinsonism. Sixteen patients with PNFA according to current consensus criteria were studied. Three patients had a corticobasal syndrome (CBS) and two a progressive supranuclear palsy (PSP) syndrome. Speech, orofacial and limb praxis f...
Source: Journal of Neurology - November 12, 2009 Category: Neurology Tags: Journal of Neurology Source Type: journals

2010 ASN AbstractsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: VBD can enlarge to significant dimensions, producing compressive symptoms in the brainstem, as well as thrombosis and ischemic strokes. SACE of the dolichoectasia can be effective for the vessel reconstruction, to prevent progression of the dilatation, and other potential clinical events. 3. Three Case Reports of Multiple Carotid and/or Vertebral Artery Dissections in Female Mei Lu, Heather Gornik, Esteban Cheng Ching, Vikram Kashyap, Rishi Gupta Cleveland Clinic Foundation, Cleveland, OH 44195, United States Introduction: Multiple carotid and/or vertebral artery dissections are rare. However, patients with mul...
Source: Journal of Neuroimaging - November 11, 2009 Category: Radiology Source Type: journals

Words, Gestures Are Translated by Same Brain Regions: Findings May Further Our Understanding of How Language EvolvedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: National Institute on Deafness and Other Communication Disorders Related MedlinePlus Topics: Aphasia, Speech and Communication Disorders (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - November 10, 2009 Category: Consumer Health News Source Type: consumer

Clinical syndromes associated with posterior atrophy: Early age at onset AD spectrumEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Logopenic progressive aphasia and posterior cortical atrophy showed largely overlapping anatomic and biologic features with early age at onset of Alzheimer disease, suggesting that these clinical syndromes represent the spectrum of clinical manifestation of the nontypical form of Alzheimer disease that presents at an early age. AD = Alzheimer disease; CBD = corticobasal degeneration; EO-AD = early age at onset of Alzheimer disease; LPA = logopenic progressive aphasia; MAC = Memory and Aging Center; PCA = posterior cortical atrophy; PIB = Pittsburgh Compound-B; PPA = primary progressive aphasia; UCSF = Universi...
Source: Neurology - November 9, 2009 Category: Neurology Authors: Migliaccio, R., Agosta, F., Rascovsky, K., Karydas, A., Bonasera, S., Rabinovici, G. D., Miller, B. L., Gorno-Tempini, M. L. Tags: MRI, Volumetric MRI, Alzheimer's disease, Dementia aphasia ARTICLES Source Type: journals

Multifocal Paraneoplastic Cortical Encephalitis Associated With Myasthenia Gravis and Thymoma [Observation]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Thymoma and myasthenia gravis may be associated with other autoimmune neurological disorders including paraneoplastic encephalitis. This second case of thymoma-associated multifocal cortical encephalitis demonstrates that autoimmune encephalitis can extend to cortical regions outside the limbic system. Autoimmune encephalitis should be considered in the differential diagnosis of patients with myasthenia gravis or thymoma who develop new cognitive symptoms. (Source: Archives of Neurology)
Source: Archives of Neurology - November 9, 2009 Category: Neurology Authors: Hammoud, K., Kandimala, G., Warnack, W., Vernino, S. Tags: Neurology, Encephalitis, Myasthenia Gravis, Neuromuscular diseases, Diagnosis, Immunology, Immunologic Disorders Observation Source Type: journals

Endovascular treatment for moyamoya disease in a Caucasian twin with angioplasty and Wingspan stentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: The pathogenesis and genetics of moyamoya disease (MMD) remain a mystery. Here we report a case of female Caucasian adult twins with similar presentations of bilateral MMD that were treated with different surgical modalities. One twin was treated with a bypass and remains event free (defined as either transient ischemic event or stroke) at her 4-year follow-up. The second twin underwent angioplasty to treat a left middle cerebral artery stenosis as well as the placement of a Wingspan stent to treat a right supraclinoid ICA stenosis on separate occasions. The left middle cerebral artery angioplasty thrombosed due ...
Source: Clinical Neurology and Neurosurgery - November 4, 2009 Category: Neurosurgery Authors: Doniel Drazin, Mark Calayag, Edward Gifford, John Dalfino, Junichi Yamamoto, Alan S. Boulos Tags: Case reports Source Type: journals

Aphasia burden to hospitalised acute stroke patients: need for an early rehabilitation programmeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of our study is to evaluate the frequency of aphasia and to describe the characteristics of aphasics among a large sample of acute stroke patients in Italy. Out of the 11 572 stroke patients hospitalised within 48 h from stroke onset, included in the PROSIT study, we selected 9594 alert cases for the estimation of aphasia frequency. The presence of aphasia was accepted when registered in the clinical records at the first neurological examination. All patients/caregivers underwent to a 2-year telephone follow-up evaluation. Twenty-eight per cent of alert acute stroke patients had aphasia, which was associated with a...
Source: International Journal of Stroke - November 4, 2009 Category: Neurology Authors: A. Bersano, F. Burgio, M. Gattinoni, L. Candelise Tags: Original articles Source Type: journals

Reconciling the perspective of practitioner and service user: findings from The Aphasia in Scotland study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions & Implications: The findings from this study indicate that although there are clearly common perspectives, the views of people with aphasia about services do not necessarily coincide with those of service providers. This is an important consideration when initiating consultation and highlights the need for clarity on the part of practitioners in identifying the aims and objectives of their ervices as far as people with aphasia are concerned. PMID: 19886848 [PubMed - as supplied by publisher] (Source: International Journal of Language and Communication Disorders)
Source: International Journal of Language and Communication Disorders - November 4, 2009 Category: Speech Therapy Authors: Law J, Huby G, Irving AM, Pringle AM, Conochie D, Haworth C, Burston A Tags: Int J Lang Commun Disord Source Type: journals

Isolated CNS vasculitis: Unusual presentation of relapsed Ewing sarcomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a 12-year-old boy male who presented with an expressive dysphasia after completion of treatment for unifocal Ewing sarcoma. CNS vasculitis was diagnosed by MRI/MRA and cerebral angiography. Extensive rheumatologic work-up failed to identify an underlying primary process. Restaging studies showed no evidence of tumor. Complete neurologic recovery was achieved on prednisone. Four months later the patient developed overt, extensive metastases, confirmed by biopsy to represent recurrent Ewing sarcoma. Despite intensive therapy the patient succumbed 6 months later. This case demonstrates the unique finding of isolat...
Source: Pediatric Blood and Cancer - November 3, 2009 Category: Cancer & Oncology Authors: Polina Stepensky, Elisha Waldman, Natalia Simanovsky, Iris Fried, Shoshana Revel-Vilk, Igor B. Resnick, Michael Weintraub Source Type: journals

Cerebral venous sinus thrombosis associated with oral contraceptives: the case for neurosurgery.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Cerebral venous sinus thrombosis secondary to oral contraception in young women, including lesions in critical and deep regions, can be treated medically with acceptable morbidity. In spite of this, a subgroup of patients needed basic neurosurgical management of the lesions, including surgical measures for controlling raised ICP. PMID: 19877796 [PubMed - in process] (Source: Neurosurgical Focus)
Source: Neurosurgical Focus - November 1, 2009 Category: Neurosurgery Authors: Galarza M, Gazzeri R Tags: Neurosurg Focus Source Type: journals

Dirofilaria repens infection and concomitant meningoencephalitis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Dirofilaria repens, a filarial nematode of dogs and other carnivores, can accidentally infect humans. Clinical symptoms are usually restricted to a subcutaneous nodule containing a single infertile parasite. Here, we report a case of D. repens infection with a subcutaneous gravid worm and the patient's concomitant meningoencephalitis and aphasia. PMID: 19891881 [PubMed - in process] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - November 1, 2009 Category: Infectious Diseases Authors: Poppert S, Hodapp M, Krueger A, Hegasy G, Niesen WD, Kern WV, Tannich E Tags: Emerg Infect Dis Source Type: journals

Acute Stroke Symptoms: Comparing Women and Men: Lisabeth LD, Brown DL, Hughes R, Majersik JJ, Morgenstern LB. Stroke 2009;40:2031–6Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This retrospective study from the University of Michigan Hospital examined the prevalence of traditional vs. non-traditional stroke and transient ischemic attack (TIA) symptoms as they are reported by women vs. men. Over a 3-year period, emergency department and admission logs were tracked and interviews were conducted with each patient or his or her proxy if a patient was unable to participate. Preceding symptom information was collected and classified as traditional or non-traditional based on the American Stroke Association's published stroke warning signs. Traditional symptoms included hemi-body numbness, diplopia, oth...
Source: The Journal of Emergency Medicine - November 1, 2009 Category: Emergency Medicine Authors: Margaret Sande Tags: Abstracts Source Type: journals

Review paper Transcranial magnetic stimulation in the therapy of selected post-stroke cognitive deficits: aphasia and visuospatial hemineglectEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Over the last several years functional neuroimaging studies and neurophysiological investigations have provided greater insight into the mechanisms underlying neuroplasticity and recovery after stroke. Various techniques became available for the non-invasive modulation of human brain activity and allowed better rehabilitation programmes to be designed. One of these new techniques is transcranial magnetic stimulation (TMS). It is a painless brain stimulation technique that modulates cortical activity. Regularly repeated TMS delivered to a single scalp position (repetitive TMS, rTMS) has an effect on cortical excitability th...
Source: Articles of Polish Journal of Neurology and Neurosurgery - TERMEDIA publishing house - October 30, 2009 Category: Neurosurgery Source Type: journals

Needs, barriers and facilitators experienced by spouses of people with aphasia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Results confirm the long-term needs of spouses in adjusting to the aphasia of their partner, as well as the limited services available to them. Many of the needs reflected spouses' concerns about their partner, while others were a consequence of their caregiving role as well as the unavailability of support. Spouses of people with aphasia should have access to support during and after rehabilitation. PMID: 19874212 [PubMed - as supplied by publisher] (Source: Disability and Rehabilitation)
Source: Disability and Rehabilitation - October 30, 2009 Category: Rehabilitation Authors: Le Dorze G, Signori FH Tags: Disabil Rehabil Source Type: journals

Alzheimer's disease neuropathologic changes in semantic dementia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: family history of late onset dementia, APOEepsilon4 status, combined features of semantic dementia and progressive non-fluent aphasia present early in illness, or generalized seizures, may indicate AD as the underlying pathology of semantic dementia. PMID: 19866390 [PubMed - as supplied by publisher] (Source: Neurocase)
Source: Neurocase - October 28, 2009 Category: Neurology Authors: Chow TW, Varpetian A, Moss T, Vinters HV, Marquez S, Miller C Tags: Neurocase Source Type: journals

A new subtype of frontotemporal lobar degeneration with FUS pathologyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Frontotemporal dementia (FTD) is a clinical syndrome with a heterogeneous molecular basis. The neuropathology associated with most FTD is characterized by abnormal cellular aggregates of either transactive response DNA-binding protein with Mr 43 kDa (TDP-43) or tau protein. However, we recently described a subgroup of FTD patients, representing around 10%, with an unusual clinical phenotype and pathology characterized by frontotemporal lobar degeneration with neuronal inclusions composed of an unidentified ubiquitinated protein (atypical FTLD-U; aFTLD-U). All cases were sporadic and had early-onset FTD with severe progress...
Source: Brain - October 27, 2009 Category: Neurology Authors: Neumann, M., Rademakers, R., Roeber, S., Baker, M., Kretzschmar, H. A., Mackenzie, I. R. A. Tags: Original Articles Source Type: journals

A Swedish family with de novo α-synuclein A53T mutation: Evidence for early cortical dysfunctionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: A de novo α-synuclein A53T (p.Ala53 Th; c.209G > A) mutation has been identified in a Swedish family with autosomal dominant Parkinson's disease (PD). Two affected individuals had early-onset (before 31 and 40 years), severe levodopa-responsive PD with prominent dysphasia, dysarthria, and cognitive decline. Longitudinal clinical follow-up, EEG, SPECT and CSF biomarker examinations suggested an underlying encephalopathy with cortical involvement. The mutated allele (c.209A) was present within a haplotype different from that shared among mutation carriers in the Italian (Contursi) and the Greek-American Family ...
Source: Parkinsonism and Related Disorders - October 27, 2009 Category: Neurology Authors: Andreas Puschmann, Owen A. Ross, Carles Vilariño-Güell, Sarah J. Lincoln, Jennifer M. Kachergus, Stephanie A. Cobb, Suzanne G. Lindquist, Jørgen E. Nielsen, Zbigniew K. Wszolek, Matthew Farrer, Håkan Widner, Danielle van Westen, Douglas Hägerström, Tags: Papers Source Type: journals

"Frontotemporoparietal" dementia: Clinical phenotype associated with the c.709-1G>A PGRN mutationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Patients carrying the c.709-1G>A mutation in the PGRN gene showed heterogeneous clinical and neuropsychological features and commonly developed corticobasal syndrome as the disease progressed. (Source: Neurology)
Source: Neurology - October 26, 2009 Category: Neurology Authors: Moreno, F., Indakoetxea, B., Barandiaran, M., Alzualde, A., Gabilondo, A., Estanga, A., Ruiz, J., Ruibal, M., Bergareche, A., Marti-Masso, J. F., Lopez de Munain, A. Tags: All Neuropsychology/Behavior, Frontotemporal dementia, Corticobasal degeneration, Assessment of cognitive disorders/dementia, All Genetics ARTICLES Source Type: journals

Prevalence of auditory sequelae after pyogenic meningitis in childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The results indicate the need for audiological monitoring and neurological follow-up in children with previous history of pyogenic meningitis, especially those infected in early ages, seeking to identify possible hearing impairments and to intervene as soon as possible, through specialized intervention, prothetization, and oral language rehabilitation. (Source: Revista da Sociedade Brasileira de Fonoaudiologia)
Source: Revista da Sociedade Brasileira de Fonoaudiologia - October 23, 2009 Category: Audiology Source Type: journals

Introduction of augmentative and alternative communication in aphasia therapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sabe-se que o tratamento fonoaudiológico de pacientes com afasia severa é limitado. A ausência de fala articulada, algumas vezes, impede o diagnóstico da afasia. O paciente "grave" pode não falar devido à inabilidade de articulação, como ocorre na disartria e/ou apraxia. Essa ausência de fala não permite afirmar se a linguagem está comprometida. O uso da comunicação suplementar e alternativa tem sido um método eficaz na reabilitação desses pacientes. Esse estudo visou descrever o uso da comunicação suplementar e alternativa associada a outras modalidades de linguagem (escrita, gestos), a partir do relato ...
Source: Revista da Sociedade Brasileira de Fonoaudiologia - October 23, 2009 Category: Audiology Source Type: journals

[A case of temporary nonthrombotic hemiplegia and aphasia due to neurotoxicity from angiographic contrast material?]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present the case of a 75-year-old woman who suddenly developed hemiplegia, aphasia, and reduced consciousness three hours after embolization of a cerebral aneurysm. No complications occurred during embolization and the findings at end-procedure angiography were normal. Cranial computed tomography (CT) after embolization showed hyperdensity of the cortex and sulci of the convexity; another CT examination performed four hours later showed these findings had disappeared. Cerebral arteriography 24h after embolization showed delayed blood flow to the parenchyma of the left hemisphere compared to the right but no vascular occ...
Source: Radiologia - October 21, 2009 Category: Radiology Authors: Paúl L, Vicente JM, Pastorín R, Casasco A Tags: Radiologia Source Type: journals

Social participation through the eyes of people with aphasia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Social participation is a theoretical concept that people with aphasia do not use. Instead, people speak in terms of engagement, involvement, having a feeling of belonging. People with aphasia describe the degree of engagement in activities in social life domains (i.e. the quality of activities) as more important than the quantity of performing activities. PMID: 19839875 [PubMed - as supplied by publisher] (Source: International Journal of Language and Communication Disorders)
Source: International Journal of Language and Communication Disorders - October 19, 2009 Category: Speech Therapy Authors: Dalemans RJ, de Witte L, Wade D, van den Heuvel W Tags: Int J Lang Commun Disord Source Type: journals

Research with transcranial magnetic stimulation in the treatment of aphasiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present language results from our rTMS studies as well as imaging results from overt naming functional MRI scans obtained before and after a series of rTMS treatments. Part 3 presents results from a pilot study in which rTMS treatments were followed immediately by constraint-induced language therapy. Part 4 reviews our diffusion tensor imaging study examining the possible connectivity of the arcuate fasciculus to different parts of Broca’s area (pars triangularis, pars opercularis) and to the ventral premotor cortex. The potential role of mirror neurons in the right pars opercularis and ventral premotor cortex in...
Source: Current Neurology and Neuroscience Reports - October 13, 2009 Category: Neuroscience Tags: Current Neurology and Neuroscience Reports Source Type: journals

Biological approaches to aphasia treatmentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract In this review, we discuss the basic mechanisms of neural regeneration and repair and attempt to correlate findings from animal models of stroke recovery with clinical trials for aphasia. Several randomized controlled clinical trials involving manipulation of different neurotransmitter systems, including noradrenergic, dopaminergic, cholinergic, and glutamatergic systems, have shown signals of efficacy. Biological approaches such as anti-Nogo and cell replacement therapy have shown efficacy in preclinical models but have yet to reach proof of concept in the clinic. Finally, noninvasive cortical stim...
Source: Current Neurology and Neuroscience Reports - October 13, 2009 Category: Neuroscience Tags: Current Neurology and Neuroscience Reports Source Type: journals

Knowledge is BLISS: an investigation into the transparency of BLISS symbol strings directed by a person with aphasia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions and Implications: Individuals without aphasia are able to match symbol strings to pictures without teaching. Further research is required to establish whether people with aphasia can similarly match the adapted version of BLISS to pictures. This study provides further evidence that people with aphasia can engage productively in the research process, even when experimental methodologies are employed. PMID: 19821792 [PubMed - as supplied by publisher] (Source: International Journal of Language and Communication Disorders)
Source: International Journal of Language and Communication Disorders - October 12, 2009 Category: Speech Therapy Authors: O'Donnell T, Bruce C, Black M, Clayton A Tags: Int J Lang Commun Disord Source Type: journals

NIH Grant To Study Brain Disorder Among ChineseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A new University of Central Florida study could help tens of thousands of Chinese-Americans who have difficulty speaking after they suffer from strokes or other illnesses. Assistant Professor Anthony Kong of Communication Sciences & Disorders has been awarded a first-of-its-kind $727,000 National Institutes of Health grant to research aphasia among Chinese speakers. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 10, 2009 Category: Consumer Health News Tags: Stroke Source Type: news

Making sense of progressive non-fluent aphasia: an analysis of conversational speechEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study selected 15 patients with progressive aphasia on broad criteria, excluding only those with clear semantic dementia. It aimed to provide a detailed quantitative description of their conversational speech, along with cognitive testing and visual rating of structural brain imaging, and to examine which, if any features were consistently present throughout the group; as well as looking for sub-syndromic associations between these features. A consistent increase in grammatical and speech sound errors and a simplification of spoken syntax relative to age-matched controls were observed, though telegraphic speech was ra...
Source: Brain - October 8, 2009 Category: Neurology Authors: Knibb, J. A., Woollams, A. M., Hodges, J. R., Patterson, K. Tags: Original Articles Source Type: journals

Emergence from minimally conscious state: Insights from evaluation of posttraumatic confusionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Accuracy for simple orientation yes/no questions remains challenging for responsive patients in early recovery from traumatic brain injury. Although name recognition questions are relatively easier than other types of yes/no questions, including situational orientation questions, confused patients still may answer these incorrectly. Results suggest the operational threshold for yes/no response accuracy as a diagnostic criterion for emergence from the minimally conscious state should be revisited, with particular consideration of the type of yes/no questions and the requisite accuracy threshold for responses. (Source: Neurology)
Source: Neurology - October 5, 2009 Category: Neurology Authors: Nakase-Richardson, R., Yablon, S. A., Sherer, M., Nick, T. G., Evans, C. C. Tags: Coma, Brain trauma, Delirium ARTICLES Source Type: journals

Regional changes in word-production laterality after a naming treatment designed to produce a rightward shift in frontal activity.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Five nonfluent aphasia patients participated in a picture-naming treatment that used an intention manipulation (opening a box and pressing a button on a device in the box with the left hand) to initiate naming trials and was designed to re-lateralize word production mechanisms from the left to the right frontal lobe. To test the underlying assumption regarding re-lateralization, patients participated in fMRI of category-member generation before and after treatment. Generally, the four patients who improved during treatment showed reduced frontal activity from pre- to post-treatment fMRI with increasing concentration of...
Source: Brain and Language - October 4, 2009 Category: Neurology Authors: Crosson B, Moore AB, McGregor KM, Chang YL, Benjamin M, Gopinath K, Sherod ME, Wierenga CE, Peck KK, Briggs RW, Gonzalez Rothi LJ, White KD Tags: Brain Lang Source Type: journals

The Northwestern Anagram Test: Measuring Sentence Production in Primary Progressive AphasiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article describes the Northwestern Anagram Test (NAT), a new clinical measure of sentence production. A total of 16 patients with PPA and their controls assembled single printed words to create sentences describing pictures. Northwestern Anagram Test performance was significantly correlated with a measure of sentence production and with aphasia severity but not with measures of naming, single word comprehension, object recognition, or motor speech. The NAT can be used to assess syntax competence when patients cannot be tested with measures that require intact speech production. (Source: American Journal of Alzheimer's...
Source: American Journal of Alzheimer's Disease and Other Dementias - October 2, 2009 Category: Geriatrics Authors: Weintraub, S., Mesulam, M.-M., Wieneke, C., Rademaker, A., Rogalski, E. J., Thompson, C. K. Tags: Articles Source Type: journals

Review of Issue: Primary Progressive Aphasia and Caregiver IssuesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - October 2, 2009 Category: Geriatrics Authors: Lippa, C. F. Tags: Articles Source Type: journals

Syntax and conversation in aphasia. A strategic restrictive use of Spanish and Catalan connector QUE by aphasic speakers.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Oral conversational data are deemed to be a relevant empirical source when it comes to formulating and supporting hypotheses about cognitive processes involved in aphasic linguistic production. With this assumption in mind, free conversational uses of the Spanish and Catalan connector QUE by fluent and non-fluent aphasic speakers are examined by contrasting them with normal speakers' (i.e. conversational partners') productions. Strictly ungrammatical uses in aphasic speakers are practically non-existent in free conversation. Nevertheless, this data permits one to characterize the aphasic production of the morpheme QUE ...
Source: Clinical Linguistics and Phonetics - October 1, 2009 Category: Speech Therapy Authors: Hernández-Sacristán C, Rosell-Clari V Tags: Clin Linguist Phon Source Type: journals

Consciousness and speech evaluation of 96 patients with craniocerebral injury.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: For the patients with injury in the language center, evaluation of the conscious state with GCS scoring system has certain limitations and conscious behaviours are advantageous evidences to evaluate the consciousness recovery of the patients. The patients with conscious disturbance and injury in the language center should be considered to have aphasia. PMID: 19788850 [PubMed - in process] (Source: Chinese Journal of Traumatology)
Source: Chinese Journal of Traumatology - September 30, 2009 Category: Orthopaedics Authors: Guo CJ, Wang YC, Zhao Y, Liu N, Liu YJ, Dong T Tags: Chin J Traumatol Source Type: journals

Ipsilateral Deficits in 1-Handed Shoe Tying After Left or Right Hemisphere StrokeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Ipsilesional shoe tying is similarly impaired after left or right hemisphere damage, but for different reasons. Spatial deficits had a greater influence after right hemisphere damage, and limb apraxia had a greater influence after left hemisphere damage. Language deficits did not affect performance, indicating that aphasia does not preclude using this therapy approach. These results suggest that rehabilitation professionals should consider assessment of limb apraxia and ipsilesional skill training in the performance of everyday tasks. (Source: Archives of Physical Medicine and Rehabilitation)
Source: Archives of Physical Medicine and Rehabilitation - September 30, 2009 Category: Rehabilitation Authors: Janet L. Poole, Joseph Sadek, Kathleen Y. Haaland Tags: Original Articles Source Type: journals

Poster 13: Language Improves in Chronic Aphasia after Motor Therapy for Upper Extremity Hemiparesis: A Case SeriesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Data confirm that interventions focused on motor rehabilitation can sometimes cause language changes. To our knowledge, these are the first data confirming this long held clinical tenet. (Source: Archives of Physical Medicine and Rehabilitation)
Source: Archives of Physical Medicine and Rehabilitation - September 30, 2009 Category: Rehabilitation Authors: Stacy Harnish, Marcus Meinzer, Jonathan Trinastic, Stephen Page Tags: Early Career Development Source Type: journals

Poster 66: Comparing Skill Acquisition Using a Cognitive-Based Treatment Approach to Contemporary Occupational Therapy in Stroke: A Pilot Randomized Controlled TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Preliminary analysis indicates larger improvements in skill performance in the CO-OP group compared to the COT group, as rated by both therapists and participants. Study limitations include non-blinding and small sample size, but the results are promising, warranting a larger-scale investigation. (Source: Archives of Physical Medicine and Rehabilitation)
Source: Archives of Physical Medicine and Rehabilitation - September 30, 2009 Category: Rehabilitation Authors: Sara McEwen, Helene J. Polatajko, Jennifer D. Ryan, Carolyn Baum Tags: Stroke Source Type: journals

Generalized and Symptom-Specific Insight in Behavioral Variant Frontotemporal Dementia and Primary Progressive Aphasia [REGULAR ARTICLES]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study used the Frontal Behavioral Inventory to compare patient and caregiver concepts of symptom presence and severity. Patients with behavioral variant FTD were found to have worse insight overall than PPA patients. However, the PPA group showed reduced insight into behavioral symptoms, and the behavioral variant FTD groups had intact insight into some language symptoms. Theoretical and clinical implications are discussed. (Source: J Neuropsychiatry Clin Neurosci)
Source: J Neuropsychiatry Clin Neurosci - September 22, 2009 Category: Neurology Authors: Banks, S. J., Weintraub, S. Tags: REGULAR ARTICLES Source Type: journals

Paraneoplastic extra limbic encephalitis associated with thymoma [Case report - Thoracic oncologic]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the case of a 55-year-old woman with thymoma diagnosed after finding of extra limbic encephalitis. She presented neurologic symptoms as seizure and aphasia; magnetic resonance imaging (MRI) of the brain showed multiple lesions located in insular, parietal and temporal lobes (in cortical and sub-cortical area). Brain biopsies confirmed the diagnosis of encephalitis and CT-scan of the thorax showed an anterior mediastinal mass suspected for thymoma. The patient was submitted to thymectomy through a median sternotomy and we assisted to secondary reduction of cerebral lesions and total remission of symptoms. (Source:...
Source: Interactive CardioVascular and Thoracic Surgery - September 21, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Rizzardi, G., Campione, A., Scanagatta, P., Terzi, A. Tags: Case report - Thoracic oncologic Source Type: journals

Imaging short- and long-term training success in chronic aphasiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The results show for the first time that treatment-induced language recovery in the chronic stage after stroke is a dynamic process. Initially, brain regions involved in memory encoding, attention, and multimodal integration mediated treatment success. In contrast, long-term treatment success was predicted mainly by activity increases in the so-called 'classical' language regions. The results suggest that besides perilesional and homologue language-associated regions, functional integrity of domain-unspecific memory structures may be a prerequisite for successful (intensive) language interventions. (Source: BM...
Source: BMC Neuroscience - Latest articles - September 21, 2009 Category: Neuroscience Authors: Ricarda MenkeMarcus MeinzerHarald KugelMichael DeppeAnnette BaumgartnerHagen SchiffbauerMarion ThomasKira KramerHubertus LohmannAgnes FloelStefan KnechtCaterina Breitenstein Source Type: journals

Good recovery from aphasia is also supported by right basal ganglia: a longitudinal controlled PET study EJPRM-ESPRM 2008 Award Winner.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The crucial role of the left temporal activation is confirmed and its increase is linked to behavioural recovery. The role of the right basal ganglia to support good recovery from aphasia is a new finding. Their activation may be more task-dependant and related to inhibition of the right frontal cortex. PMID: 19794392 [PubMed - as supplied by publisher] (Source: European Journal of Physical and Rehabilitation Medicine)
Source: European Journal of Physical and Rehabilitation Medicine - September 21, 2009 Category: Rehabilitation Authors: De Boissezon X, Marie N, Castel-Lacanal E, Marque P, Bezy C, Gros H, Lotterie JA, Cardebat D, Puel M, Demonet JF Tags: Eur J Phys Rehabil Med Source Type: journals

ORIGINAL CONTRIBUTION: Multiple Sclerosis With Predominant, Severe Cognitive ImpairmentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions We describe patients with MS whose clinical phenotype is characterized by severe cognitive dysfunction and prominent cortical and psychiatric signs presenting as a subacute fulminant or chronic progressive clinical course. Cigarette smokers may be overrepresented in this phenotype. (Source: Archives of Neurology)
Source: Archives of Neurology - September 13, 2009 Category: Neurology Authors: Staff, N. P., Lucchinetti, C. F., Keegan, B. M. Tags: Neurology, Cognitive Disorders, Multiple Sclerosis/ Demyelinating Disease, Immunology, Immunologic Disorders Original Contribution Source Type: journals

Putaminal Volume in Frontotemporal Lobar Degeneration and Alzheimer Disease: Differential Volumes in Dementia Subtypes and Controls [BRAIN]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Right putaminal volume was significantly smaller in FTD, the FTLD subtype with the greatest expected frontostriatal dysfunction; whereas in SD and PNFA, it showed a trend towards being smaller, consistent with expectation, compared to controls and AD; and in SD, compared with AD and controls. Putaminal volume weakly correlated with MMSE. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - September 10, 2009 Category: Radiology Authors: Looi, J.C.L., Svensson, L., Lindberg, O., Zandbelt, B.B., Ostberg, P., Orndahl, E., Wahlund, L.-O. Tags: BRAIN Source Type: journals

Acute ischemic infarct in the middle cerebral artery territory following a Russell's viper biteEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report an 18-year male who developed right hemiplegia with expressive aphasia following a Russell's viper bite. T2-weighted magnetic resonance imaging revealed infarct in the left middle cerebral artery territory. The possible mechanisms for cerebral infarction in this scenario include disseminated intravascular coagulation, toxin induced vasculitis and endothelial damage. (Source: Neurology India)
Source: Neurology India - September 10, 2009 Category: Neurology Authors: Narang Sanjeev K, Paleti Srikanth, Azeez Asad M A, Samina Tarannum Source Type: journals

Jenny Dautlich Wins Prestigious Robin Tavistock AwardEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The Trustees of the Tavistock Trust for Aphasia are delighted to announce that Dr Jenny Dautlich DFPH is the 4th recipient of The Robin Tavistock Award. (Source: Speakability)
Source: Speakability - September 9, 2009 Category: Speech Therapy Source Type: organizations

A case of Sturge–Weber syndrome with symptomatic hemiplegic migraine: Clinical and multimodality imaging data during a prolonged attackEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Hemiplegic migraine (HM) in the setting of Sturge–Weber syndrome (SWS) has been previously described. Here, we report clinical and multimodal imaging data on a 21-year-old man with SWS and HM, who presented during an acute HM attack with a dense left-hemispheric syndrome (expressive aphasia and right sensorimotor hemiplegia), lasting for more than 10days. Repeated EEGs were without evidence of status epilepticus. Consistent with previous findings in prolonged migraine aura, perfusion computed tomography demonstrated left-hemispheric hyperperfusion on day 7. 18F-FDG positron emission tomography (day 7) revealed ...
Source: Journal of the Neurological Sciences - September 7, 2009 Category: Neurology Authors: Tobias Freilinger, Nils Peters, Jan Rémi, Jennifer Linn, Marcus Hacker, Andreas Straube, Thomas Pfefferkorn Tags: Short Communications Source Type: journals

Case report Primary progressive aphasia: primary nonfluent aphasia or logopenic aphasia? A case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a case of a 58-year-old female suffering from progressive language difficulties with characteristic symptoms of primary progressive aphasia (PPA) who was finally diagnosed as having progressive nonfluent aphasia variant (PNFA). The differential diagnosis was made between a variant of PNFA and logopenic variant of PPA occurring often in the course of Alzheimer’s disease. (Source: Articles of Polish Journal of Neurology and Neurosurgery - TERMEDIA publishing house)
Source: Articles of Polish Journal of Neurology and Neurosurgery - TERMEDIA publishing house - September 4, 2009 Category: Neurosurgery Source Type: journals

Abstracts from the Special Care Dentistry 21st Annual Meeting can be accessed in the electronic version of this issue at interscience.wiley.comEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study's purpose was to note trends in the prevalence of oral manifestations of HIV and assess variations in the dental care of adults with HIV given the current use of antiretroviral therapy in both the industrialized world and developing nations. A comprehensive review of the English literature was completed on the incidence and prevalence of oral diseases and the types of dental services that provided comprehensive oral care to patients who have been HIV positive since 1980. The study concluded that significant and similar disparities exist in the use of dental health services for both patients with HIV and the gene...
Source: Special Care in Dentistry - September 2, 2009 Category: Dentistry Tags: ABSTRACT Source Type: journals

Women and stroke: how much do women and men differ? A review--diagnostics, clinical differences, therapy and outcome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this article, the authors have gathered data from epidemiological, observational, case-control and cohort studies to evaluate the differences between men and women in terms of ischemic events, mainly stroke. The authors are highlighting the differences that exist between men and women and play a role in terms of social diversities, and the pathophysiological differences that may be responsible at least in part for ischemic events. Studies show that male stroke patients are more likely to have a history of ischemic heart disease, smoking and alcohol consumption, whereas female stroke patients suffer from ischemic eve...
Source: Collegium Antropologicum - September 1, 2009 Category: Epidemiology Authors: Vuković V, Galinović I, Lovrencić-Huzjan A, Budisić M, Demarin V Tags: Coll Antropol Source Type: journals

Oropharyngeal Dysphagia after Stroke: Incidence, Diagnosis, and Clinical Predictors in Patients Admitted to a Neurorehabilitation UnitEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Dysphagia occurs in more than a third of patients with stroke admitted to rehabilitation. Clinical assessment demonstrates good correlation with VFS. The grade of dysphagia correlates with dysarthria, aphasia, low FIM, and level of cognitive functioning. Large cortical strokes of nondominant side are associated with dysphagia. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - August 31, 2009 Category: Neurology Authors: Paolo Falsetti, Caterina Acciai, Rosanna Palilla, Marco Bosi, Francesco Carpinteri, Alberto Zingarelli, Claudio Pedace, Lucia Lenzi Tags: Original Articles Source Type: journals

Jonathan Osborne (1794-1864) MD FRCPI: a crypto-neurologistEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Jonathan Osborne was born in Dublin and educated in Trinity College Dublin, where he became Professor of Materia Medica. As physician to Sir Patrick Dun's and Mercer Hospitals he reported extensively on those patients who came under his care. In his native city he is remembered for the instruments he devised, for his studies on dropsies (particularly albuminuric nephritis), and for his therapeutic approach to epilepsy and neuralgia. It is his thorough analysis of a patient with conduction aphasia in 1833, however, which has stood the test of time. (Source: Journal of Medical Biography)
Source: Journal of Medical Biography - August 31, 2009 Category: History of Medicine Authors: Breathnach, C. S Tags: Neurologists Source Type: journals