Miller Fisher Syndrome: General Overview & Information
Miller Fisher Syndrome or, 'MFS,' is a post-infectious, immune mediated neuropathy characterized in typical instances by the clinical triad of ataxia, areflexia and ophthalmoplegia. MFS is considered to be a variant of Guillain-Barre syndrome or, 'GBS.' The clinical symptoms usually develop within days and improve spontaneously or following treatment within a period of weeks. People with MFS often show only part of the clinical triad. (Source: Disabled World)
Source: Disabled World - December 22, 2015 Category: Disability Tags: Neurological Disorders Source Type: news
Certain herpes viruses can infect human neurons
(University of Pennsylvania School of Medicine) A tantalizing link exists between some neurologic conditions and certain species of herpes virus. In some patients with Alzheimer's disease, multiple sclerosis, and cerebellar ataxia, among others, the cerebrospinal fluid teems with Epstein-Barr virus. Yet, the link remains unclear. It's been assumed that EBV, and viruses in the same family cannot infect neurons. Now, researchers have shown that EBV and Kaposi's sarcoma-associated herpesvirus can infect and replicate in cultured and primary neurons. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 4, 2015 Category: Infectious Diseases Source Type: news
Genetic defect underlying a rare disease identified
The genetic cause has been identified for a rare disease characterized by life-threatening "liver crises" in early childhood and subsequent manifestation of neurological symptoms, such as neuropathy and ataxia (a movement disorder), when the patient reaches school age. In 2007 the same researchers published a mutation in the Scyl1 gene in a naturally occurring mouse mutant with similar symptoms. Using next-generation sequencing techniques, they have now succeeded in identifying the first cases of a corresponding condition in humans. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 13, 2015 Category: Science Source Type: news
Genomics Moves From the Lab to the Doctor's Office
By Diana Brazzell, Co-Founder & Executive Editor, Footnote
This post was originally published on Footnote, a website that brings academic research and ideas to a broader audience.
Since the discovery of DNA, people have anticipated how deciphering the secrets in our genes might one day transform medicine. The first commonly used genetic tests appeared in the 1970s and the full human genome was sequenced in 2003. But it is only in the past decade, as sequencing technology advanced rapidly and the price tag plummeted, that genomic medicine has started to become a reality.(a) We're finally gaining access to a huge piece of ...
Source: Science - The Huffington Post - October 15, 2015 Category: Science Source Type: news
Autoimmune Cerebellar Ataxia May Respond to ImmunotherapyAutoimmune Cerebellar Ataxia May Respond to Immunotherapy
A new study of patients with autoimmune cerebellar ataxia, often a complication of cancer, has found it is not always untreatable and that many patients respond well to immunotherapy, particularly if started early. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - September 30, 2015 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news
Autoimmune cerebellar ataxia
(Mayo Clinic) While autoimmune cerebellar ataxia (a loss of muscle control coordination) can lead to severe disability with some patients becoming wheelchair-bound, there are factors that may help predict better immunotherapy response, according to the Mayo Clinic study published by JAMA Neurology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 29, 2015 Category: Global & Universal Source Type: news
Autoimmune cerebellar ataxia: Study finds treatment promises for a disease previously considered hopeless
ROCHESTER, Minn. — While autoimmune cerebellar ataxia (a loss of muscle control coordination) can lead to severe disability with some patients becoming wheelchair-bound, there are factors that may help predict better immunotherapy response, according to the Mayo Clinic study published by JAMA Neurology. https://www.youtube.com/watch?v=tsriW0BD638 Autoimmune cerebellar ataxia in adults, which usually comes on rapidly and [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - September 29, 2015 Category: Databases & Libraries Source Type: news
Coordinating traffic down the neuronal highway
An international team of researchers has identified a protein that regulates the growth of neurons by transporting key metabolic enzymes to the tips of neural cells. Their findings open up new avenues for design of drugs for ataxia, a motor coordination disorder. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 18, 2015 Category: Science Source Type: news
Coordinating traffic down the neuronal highway
A protein that regulates the growth of neurons by transporting key metabolic enzymes to the tips of neural cells has been identified by an international team of researchers. Their findings open up new avenues for design of drugs for ataxia, a motor coordination disorder. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 18, 2015 Category: Science Source Type: news
University of South Florida and Friedreich's Ataxia Research Alliance to host scientific symposium
(University of South Florida (USF Health)) The University of South Florida will again bring together leading researchers and patients searching for a treatment for Friedreich's ataxia and related disorders at the seventh annual scientific symposium 'Understanding Energy for A Cure.' The symposium will be held 5:00 to 8:30 p.m., Thursday, Sept. 17, at the USF Marshall Student Center Ballroom in Tampa, FL. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 1, 2015 Category: Global & Universal Source Type: news
Henry Barber-Riley staggers around, slurs his words and vomits due to rare genetic condition
Henry Barber-Riley, five, from Lutterworth, Leicstershire, suffers from episodic ataxia type 2, which causes him to have 'episodes' in which he staggers and slurs his words. (Source: the Mail online | Health)
Source: the Mail online | Health - August 25, 2015 Category: Consumer Health News Source Type: news
More falls in cerebellar ataxia when standing on a slow up-moving tilt of the support surface - Paquette C, Franzén E, Horak FB.
We investigated how subjects with cerebellar ataxia (CA) adapt their postural stability and alignment to a slow and small tilt of the support surface allowing for online postural corrections. Eight subjects with CA and eight age- and gender-matched healthy... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - August 7, 2015 Category: Global & Universal Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Decreasing fall risk in spinocerebellar ataxia - Santos de Oliveira LA, Martins CP, Horsczaruk CH, Lima da Silva DC, Martins JV, Vasconcelos LF, Rodrigues Ede C.
[Purpose] Spinocerebellar ataxia consists of a group of autosomal dominant disorders that cause progressive degeneration, mainly in the cerebellum and its connections. Falls, which are a significant concern of this condition, reduce patients' mobility, det... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - July 22, 2015 Category: Global & Universal Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Ataxia mouse model: Eye blink conditioning for early diagnosis of human disease SCA6
Scientists have established a mouse model for the human disease SCA6. SCA6 is characterized by movement deficits and caused by similar genetic alterations as Chorea Huntington. The mouse model will be used to investigate the disease mechanisms. Experiments suggest that an impairment of eye blink conditioning could be an early disease symptom. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 17, 2015 Category: Science Source Type: news
Ataxia with Parkinsonism and dystonia after intentional inhalation of liquefied petroleum gas - Godani M, Canavese F, Migliorini S, Sette MD.
The practice of inhaling liquefied petroleum gas (LPG) to commit suicide is uncommon and almost exclusively a prerogative of the prison population. Numerous cases of sudden deaths caused by intentional propane and/or butane inhalation have been described, ... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - June 10, 2015 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news
