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Epidemiology, neurobiology and pharmacological interventions related to suicide deaths and suicide attempts in bipolar disorder: Part I of a report of the International Society for Bipolar Disorders Task Force on Suicide in Bipolar Disorder - Schaffer A, Isometsä ET, Tondo L, Moreno DH, Sinyor M, Kessing LV, Turecki G, Weizman A, Azorin JM, Ha K, Reis C, Cassidy F, Goldstein T, Rihmer Z, Beautrais A, Chou YH, Diazgranados N, Levitt AJ, Zarate CA, Yatham L.
OBJECTIVES: Bipolar disorder is associated with elevated risk of suicide attempts and deaths. Key aims of the International Society for Bipolar Disorders Task Force on Suicide included examining the extant literature on epidemiology, neurobiology and pharm... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - August 1, 2015 Category: Global & Universal Tags: Suicide and Self-Harm Source Type: news

8 Weird Things That Happen When You Send a Text
This article '8 Weird Things That Happen When You Send A Text' originally ran on Prevention.com. More from Prevention.com: 7 Things To Never Do Before Or After Sex 9 Proven Ways To Lose Stubborn Belly Fat This Haircut Will Make You Look 10 Years Younger Shrink A Size In Just 14 Days 6 Simple Moves To Ease Sciatica Also on HuffPost: -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website. (Source: Healthy Living - The Huffington Post)
Source: Healthy Living - The Huffington Post - August 1, 2015 Category: Consumer Health Advice Source Type: news

Heart Failure Hospitalizations and 30 Day Readmissions for Quadripolar and Bipolar CRT-D Systems: Results From a US Single Center Study
This study compares all cause 30 day inpatient readmissions following HF hospitalization (hosp) in patients with St. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - July 31, 2015 Category: Cardiology Authors: Raffaele Corbisiero, Pedram Kazemian, Rupinder Bharmi, Riddhi Shah, David Muller Tags: Quality of Care/Outcomes I Source Type: research

Pharmacotherapy in Bipolar Depression Comorbid With Parkinson's Disease: A Case Report.
Authors: Wang JK, Lee HC PMID: 26222973 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 31, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Prevalence and predictors of type 2 diabetes mellitus in people with bipolar disorder: a systematic review and meta-analysis.
CONCLUSIONS: T2DM is significantly more common in people with bipolar disorder than in healthy controls of similar age and sex. The current meta-analysis furthermore indicates that changes in food, built, and social environments are needed in order to curb the diabetes epidemic in this high-risk population. PMID: 26214054 [PubMed - as supplied by publisher] (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - July 31, 2015 Category: Psychiatry Tags: J Clin Psychiatry Source Type: research

The impact of depressive and bipolar symptoms on socioeconomic status, core symptoms, function and severity of fibromyalgia
ConclusionPatients with severe FM disease activity, high load of symptoms, prolonged morning stiffness, increased disability, lower socioeconomic status and those who take a lot of medications for FM should be evaluated for depressive and manic symptoms. (Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - July 31, 2015 Category: Rheumatology Authors: Carmen E. Gota, Sahar Kaouk, William S. Wilke Tags: Original Article Source Type: research

SEQUenCE: a service user-centred quality of care instrument for mental health services
Conclusions SEQUenCE is a valid, reliable scale that is grounded in the service user perspective and suitable for routine use. It may serve as a useful tool in individual care planning, service evaluation and research. The instrument was developed and validated with service users with a diagnosis of either BPAD or a psychotic disorder; it does not yet have established external validity for other diagnostic groups. (Source: International Journal for Quality in Health Care)
Source: International Journal for Quality in Health Care - July 31, 2015 Category: Global & Universal Authors: Hester, L., O' Doherty, L. J., Schnittger, R., Skelly, N., O' Donnell, M., Butterly, L., Browne, R., Frorath, C., Morgan, C., McLoughlin, D. M., Fearon, P. Tags: Papers Source Type: research

[Report] Epitaxial growth of a monolayer WSe2-MoS2 lateral p-n junction with an atomically sharp interface
We report the two-step epitaxial growth of lateral WSe2-MoS2 heterojunction, where the edge of WSe2 induces the epitaxial MoS2 growth despite a large lattice mismatch. The epitaxial growth process offers a controllable method to obtain lateral heterojunction with an atomically sharp interface. Authors: Ming-Yang Li, Yumeng Shi, Chia-Chin Cheng, Li-Syuan Lu, Yung-Chang Lin, Hao-Lin Tang, Meng-Lin Tsai, Chih-Wei Chu, Kung-Hwa Wei, Jr-Hau He, Wen-Hao Chang, Kazu Suenaga, Lain-Jong Li (Source: Science: Current Issue)
Source: Science: Current Issue - July 31, 2015 Category: Science Authors: Ming-Yang Li Source Type: research

Developmental staging models in bipolar disorder
The previous contribution of Duffy and colleagues suggests that a chain of behavioral events starting during childhood precedes the development of full-blown bipolar disorder. In this vein, the recent contribution of Keown-Stoneman and colleagues brings a new perspective to the study of prodromal symptoms of bipolar disorder. (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - July 31, 2015 Category: Psychiatry Authors: Ives PassosKaren JansenFlavio Kapczinski Source Type: research

Optimising screening for cognitive dysfunction in bipolar disorder: Validation and evaluation of objective and subjective tools
The objective was to validate and evaluate instruments to screen for and monitor cognitive impairments, and improve the understanding of the association between cognitive measures and socio-occupational capacity. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - July 31, 2015 Category: Neurology Authors: Johan Høy Jensen, Mette Marie Støttrup, Emilie Nayberg, Ulla Knorra, Henrik Ullum, Scot E. Purdon, Lars V. Kessing, Kamilla W. Miskowiak Source Type: research

Mood instability in bipolar disorder type I versus type II- continuous daily electronic self-monitoring of illness activity using smartphones
The objectives were to investigate differences in daily illness activity between bipolar disorder type I and II. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - July 31, 2015 Category: Neurology Authors: Maria Faurholt-Jepsen, Christian Ritz, Mads Frost, Rie Lambæk Mikkelsen, Ellen Margrethe Christensen, Jakob Bardram, Maj Vinberg, Lars Vedel Kessing Source Type: research

Resolution of enantiomers of bupropion and its metabolites by liquid chromatography.
This article is protected by copyright. All rights reserved. PMID: 26230937 [PubMed - as supplied by publisher] (Source: Biomedical Chromatography : BMC)
Source: Biomedical Chromatography : BMC - July 31, 2015 Category: Biomedical Science Authors: Batra S, Bhushan R Tags: Biomed Chromatogr Source Type: research

Post-thyroidectomy complications. The role of the device: Bipolar vs Ultrasonic device Collection of data from 1846 Consecutive Patients Undergoing Thyroidectomy
This multicenter study acknowledges the value of the ultrasonic device as a protective factor only for RLN palsy, confirming nodal dissection as a risk factor for postoperative hypocalcemia and vocal folds disorders (Source: American Journal of Surgery)
Source: American Journal of Surgery - July 31, 2015 Category: Surgery Authors: Maurizio De Palma, Ludovico Rosato, Fabiana Zingone, Giulio Orlando, Antonio Antonino, Mario Vitale, Alessandro Puzziello Source Type: research

Functional properties of spontaneous excitatory currents and encoding of light/dark transitions in horizontal cells of the mouse retina
Abstract As all visual information is represented in the spatio‐temporal dynamics of transmitter release from photoreceptors and the combined postsynaptic responses of second‐order neurons, appropriate synaptic transfer functions are fundamental for a meaningful perception of the visual world. The functional contribution of horizontal cells to gain control and organization of bipolar and ganglion cell receptive fields can only be evaluated with an in‐depth understanding of signal processing in horizontal cells. Therefore, a horizontal slice preparation of the mouse retina was established to record from horizontal cel...
Source: European Journal of Neuroscience - July 30, 2015 Category: Neuroscience Authors: Andreas Feigenspan, Norbert Babai Tags: Research Report Source Type: research

Identification of circadian gene variants in bipolar disorder in Latino populations
Variations in circadian genes can impact biological rhythms. Given the rhythm disturbances that characterize bipolar disorder (BD), genes encoding components of molecular clocks are good candidate genes for the illness. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - July 30, 2015 Category: Neurology Authors: Robert Gonzalez, Suzanne Gonzalez, Erika Villa, Mercedes Ramirez, Juan Zavala, Regina Armas, Javier Contreras, Albana Dassori, Robin J. Leach, Deborah Flores, Alvaro Jerez, Henriette Raventós, Alfonso Ontiveros, Humberto Nicolini, Michael Escamilla Source Type: research

Relationship between toxoplasma gondii and mood disturbance in women veterans - Duffy AR, Beckie TM, Brenner LA, Beckstead JW, Seyfang A, Postolache TT, Groer MW.
BACKGROUND: Toxoplasma gondii is an intracellular protozoan parasite with zoonotic potential that causes acute and chronic diseases, which has been associated with schizophrenia, depression, bipolar disorder, and suicidal behavior. Military personnel may b... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - July 29, 2015 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Wireless Electrochemiluminescence Bipolar Electrode Array for Visualized Genotyping of Single Nucleotide Polymorphism
Analytical ChemistryDOI: 10.1021/acs.analchem.5b02515 (Source: Analytical Chemistry)
Source: Analytical Chemistry - July 29, 2015 Category: Chemistry Authors: Seyyed Mehdi Khoshfetrat, Mitra Ranjbari, Mohsen Shayan, Masoud A. Mehrgardi and Abolfazl Kiani Source Type: research

Highly efficient yellow phosphorescent OLEDs based on two novel bipolar host materials
New J. Chem., 2015, Accepted ManuscriptDOI: 10.1039/C5NJ00939A, PaperSong Zhang, Qiulei Xu, Jing-Cheng Xia, Yi-Ming Jing, Youxuan Zheng, Jing-Lin ZuoThis is an Accepted Manuscript, which has been through the RSC Publishing peer review process and has been accepted for publication. Accepted manuscripts are published online shortly after acceptance. This version of the article will be replaced by the fully edited, formatted and proof read Advance Article as soon as this is available.The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - New J. Chem. latest articles)
Source: RSC - New J. Chem. latest articles - July 29, 2015 Category: Chemistry Authors: Song Zhang Source Type: research

Hybrid bipolar membrane electrodialysis/ultrafiltration technology assisted by pulsed electric field for casein production
Green Chem., 2015, Accepted ManuscriptDOI: 10.1039/C5GC00970G, PaperSergey Mikhaylin, Victor Nikonenko, Gerald Pourcelly, L. BazinetElectrodialysis with bipolar membranes (EDBM) is an ecofriendly technology providing a wide spectrum of solutions for modern industries. The main advantage of EDBM is the absence of chemicals during the...The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Green Chem. latest articles)
Source: RSC - Green Chem. latest articles - July 29, 2015 Category: Chemistry Authors: Sergey Mikhaylin Source Type: research

Lifting the burden of bipolar disorder: The role of psychotherapies
(Source: Australian and New Zealand Journal of Psychiatry)
Source: Australian and New Zealand Journal of Psychiatry - July 29, 2015 Category: Psychiatry Authors: Torrent, C., Vieta, E. Tags: Commentaries Source Type: research

Successful use of olfactory hallucinations as early warning sign in a patient with bipolar disorder
(Source: Australian and New Zealand Journal of Psychiatry)
Source: Australian and New Zealand Journal of Psychiatry - July 29, 2015 Category: Psychiatry Authors: Tripathi, P., Gupta, S. K., Goyal, P., Kar, S. K. Tags: Letters Source Type: research

Amisulpride monotherapy may be a choice of maintenance treatment for patients with both bipolar I disorder and metabolic syndrome
(Source: Australian and New Zealand Journal of Psychiatry)
Source: Australian and New Zealand Journal of Psychiatry - July 29, 2015 Category: Psychiatry Authors: Hong, C.-C., Chen, C.-K., Yeh, T.-C., Chu, C.-S., Chen, T.-Y. Tags: Letters Source Type: research

Interaction of ketamine and cannabis in bipolar disorder
It is with great interest that I read a recent correspondence by McInnes and colleagues (1) regarding a possible switch from depression to mania/mixed state in a female (Mrs. P) suffering from bipolar I disorder. Briefly, the authors found that the 44-year old patient treated with various outpatient medications (lithium 600mg, aripiprazole 10mg, modafinil 100mg, clonazepam 1mg and zolpidem 10mg as well as lorazepam 0.5mg on demand) developed an affective switch following a single 40-minute continuous 0.5mg/kg ketamine IV infusion. (Source: Biological Psychiatry)
Source: Biological Psychiatry - July 29, 2015 Category: Psychiatry Authors: Helge Hasselmann Tags: Correspondence Source Type: research

Onset polarity and illness course in bipolar I and II disorders: The predictive role of broadly defined mixed states
Several studies investigating bipolar disorders have shown that polarity of onset can predict differences in symptomatology, course, and prognosis. Frequently, however, research on the topic has examined only bipolar I inpatients and has not included patients with mixed onset. The aim of the present naturalistic study was to evaluate the clinical characteristics and illness course of a consecutive sample (407 outpatients, 58.7% with bipolar I (BD-I) and 41.3% with bipolar II (BD-II) disorder) according to polarity of onset: depressive (DP-o); manic/hypomanic (HM-o); or mixed--broadly defined to include agitated depression ...
Source: Comprehensive Psychiatry - July 29, 2015 Category: Psychiatry Authors: Antonio Tundo, Laura Musetti, Alessandra Benedetti, Benedetta Berti, Gabriele Massimetti, Liliana Dell'Osso Source Type: research

Daily electronic self-monitoring in bipolar disorder using smartphones - the MONARCA I trial: a randomized, placebo-controlled, single-blind, parallel group trial.
CONCLUSIONS: These results highlight that electronic self-monitoring, although intuitive and appealing, needs critical consideration and further clarification before it is implemented as a clinical tool. PMID: 26220802 [PubMed - as supplied by publisher] (Source: Psychological Medicine)
Source: Psychological Medicine - July 29, 2015 Category: Psychiatry Authors: Faurholt-Jepsen M, Frost M, Ritz C, Christensen EM, Jacoby AS, Mikkelsen RL, Knorr U, Bardram JE, Vinberg M, Kessing LV Tags: Psychol Med Source Type: research

Traumatic brain injury and bipolar psychosis in the genomic psychiatry cohort
This study demonstrates an association of TBI with psychosis in a subset of bipolar cases, suggesting that traumatic stressors may have the ability to impact gene expression in a vulnerable population, and/or there is a heightened occurrence of TBI in individuals with underlying psychosis. Further studies should more closely examine the interplay between genetic variation in bipolar disorder and susceptibility to psychosis following TBI. © 2015 Wiley Periodicals, Inc. (Source: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics)
Source: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics - July 29, 2015 Category: Genetics & Stem Cells Authors: Kristina Cieslak, Michelle Pato, Peter Buckley, Carlos Pato, Janet L. Sobell, Helena Medeiros, Yuan Zhao, Hongshik Ahn, Dolores Malaspina, Tags: Research Article Source Type: research

Cost-effectiveness of lurasidone vs quetiapine extended-release (XR) in patients with bipolar depression
Journal of Medical Economics, Ahead of Print. (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - July 28, 2015 Category: Health Management Tags: article Source Type: research

Searching for “Order” in Atrial Fibrillation using Electrogram Morphology Recurrence Plots
Bipolar electrograms recorded during atrial fibrillation (AF) can have an appearance of chaotic/random behavior. The aim of this study was to use a novel electrogram morphology recurrence (EMR) analysis to quantify the level of order in the morphology patterns in AF. (Source: Computers in Biology and Medicine)
Source: Computers in Biology and Medicine - July 28, 2015 Category: Bioinformatics Authors: David Gordon, Jeffrey J. Goldberger, Rishi Arora, Gary L. Aistrup, Jason Ng Source Type: research

Effects of a single bout of maximal aerobic exercise on BDNF in bipolar disorder: A gender-based response
The objective of the present study was to evaluate the peripheral BDNF serum response to a single maximum session of exercise in BD participants and age- and gender-matched healthy participants. BD participants (n=18) and age- and gender-matched healthy participants (n=18) were recruited to perform a single bout of maximal exercise on a cycle ergometer. (Source: Psychiatry Research)
Source: Psychiatry Research - July 28, 2015 Category: Psychiatry Authors: Felipe Barreto Schuch, Leonardo Evangelista da Silveira, Taís Cardoso de Zeni, Diana Perin da Silva, Bianca Wollenhaupt-Aguiar, Pamela Ferrari, Álvaro Reischak-Oliveira, Flavio Kapczinski Source Type: research

Memory and brain-derived neurotrophic factor after subchronic or chronic amphetamine treatment in an animal model of mania
Publication date: September 2015 Source:Journal of Psychiatric Research, Volume 68 Author(s): Gabriel R. Fries, Samira S. Valvassori, Hugo Bock, Laura Stertz, Pedro Vieira da Silva Magalhães, Edimilson Mariot, Roger B. Varela, Marcia Kauer-Sant’Anna, João Quevedo, Flávio Kapczinski, Maria Luiza Saraiva-Pereira Progression of bipolar disorder (BD) has been associated with cognitive impairment and changes in neuroplasticity, including a decrease in serum brain-derived neurotrophic factor (BDNF). However, no study could examine BDNF levels directly in different brain regions after repeated mood episodes to d...
Source: Journal of Psychiatric Research - July 28, 2015 Category: Psychiatry Source Type: research

Affective temperaments and concomitant alcohol use disorders in bipolar disorder
Alcohol misuse (AM) is more common in bipolar disorder (BD) than within the general population but the mechanisms of this association are unclear. We hypothesised that certain affective temperaments (including hyperthymic, cyclothymic, anxious, depressive and/or irritability) might represent ‘fundamental states’ contributing to risk of both AM and BD and we aimed to assess whether extremes of these five affective temperaments were associated with BD and concomitant AM status. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - July 28, 2015 Category: Neurology Authors: Sukhmeet Singh, Liz Forty, Arianna di Florio, Katherine Gordon-Smith, Ian Jones, Nick Craddock, Lisa Jones, Daniel J. Smith Source Type: research

Is religiosity a protective factor against suicidal behavior in bipolar I outpatients?
The objective of this study was to evaluate the association between religiosity and SB in euthymic bipolar I outpatients. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - July 28, 2015 Category: Neurology Authors: André C. Caribé, Paula Studart, Severino Bezerra-Filho, Elisa Brietzke, Mariane Nunes Noto, Mireia Vianna-Sulzbach, Flavio Kapczinski, Fernando Silva Neves, Humberto Correa, Ângela Miranda-Scippa Source Type: research

[Therapeutic Drug Monitoring of Olanzapine].
Abstract Olanzapine, atypical antipsychotic, is used to treat schizophrenia and bipolar disorder. Its therapeutic drug monitoring (TDM) is quite commonly done. Olanzapine is well absorbed orally (bioavailability 85%), with peak plasma occurring between 4 and 6 hours after oral administration. It is extensively metabolized by different hepatic enzymes (including CYP1A2 and CYP2D6 isoforms) to a large number of inactive metabolites, and its half-life is between 30 and 60 hours. No specific therapeutic range, or threshold concentration could not be a consensus, but the higher intra-and interindividual variability, as ...
Source: Therapie - July 28, 2015 Category: Psychiatry & Psychology Authors: Djerada Z, Brousse G, Niel P, Llorca PM, Eschalier A, Bentue-Ferrer D, Libert F Tags: Therapie Source Type: research

CDH13 and HCRTR2 May Be Associated with Hypersomnia Symptom of Bipolar Depression: A Genome-Wide Functional Enrichment Pathway Analysis.
Authors: Cho CH, Lee HJ, Woo HG, Choi JH, Greenwood TA, Kelsoe JR Abstract Although bipolar disorder is highly heritable, the identification of specific genetic variations is limited because of the complex traits underlying the disorder. We performed a genome-wide association study of bipolar disorder using a subphenotype that shows hypersomnia symptom during a major depressive episode. We investigated a total of 2,191 cases, 1,434 controls, and 703,012 single nucleotide polymorphisms (SNPs) in the merged samples obtained from the Translational Genomics Institute and the Genetic Association Information Network. The...
Source: Psychiatry Investigation - July 27, 2015 Category: Psychiatry Tags: Psychiatry Investig Source Type: research

Microstructural Changes of Anterior Corona Radiata in Bipolar Depression.
CONCLUSION: White matter abnormalities can be detected in patients with BD using DTI. The neuropathology of these abnormalities is unclear, but neuronal and axonal loss, myelin abnormalities and reduced white matter fiber density are likely to be relevant. PMID: 26207131 [PubMed] (Source: Psychiatry Investigation)
Source: Psychiatry Investigation - July 27, 2015 Category: Psychiatry Tags: Psychiatry Investig Source Type: research

Impact of Cannabis Use on Long-Term Remission in Bipolar I and Schizoaffective Disorder.
CONCLUSION: Cannabis use negatively affects the long-term clinical outcome in patients with bipolar spectrum disorders. A comprehensive assessment and integrated management of cannabis use are required to achieve better treatment outcomes for bipolar spectrum disorders. PMID: 26207128 [PubMed] (Source: Psychiatry Investigation)
Source: Psychiatry Investigation - July 27, 2015 Category: Psychiatry Tags: Psychiatry Investig Source Type: research

Long-term effects of mental disorders on employment in the National Comorbidity Survey ten-year follow-up
Conclusions Expanded access to treatment among current employees and students with mental disorders might lead to improved employment outcomes in these segments of the population. (Source: Social Psychiatry and Psychiatric Epidemiology)
Source: Social Psychiatry and Psychiatric Epidemiology - July 27, 2015 Category: Psychiatry Source Type: research

Identification of two clusters within schizophrenia with different structural, functional and clinical characteristics
Conclusions Results of this study support the existence of a biologically distinct group within the schizophrenia syndrome, characterized by increased cortical curvature values, reduced thalamic and cingulate metabolism, lack of the expected increased putaminal metabolism with antipsychotics and persistent negative symptoms. (Source: Progress in Neuro Psychopharmacology and Biological Psychiatry)
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - July 27, 2015 Category: Psychiatry Source Type: research

Impact of Atrial Fibrillation Duration on the Success of First-Time Concomitant Cox Maze Procedures
Conclusions Longer AF duration significantly impacted CM success and may result from extensive tissue remodeling. Patients with longer AF duration can expect reasonable success rates, especially when on AAD, and low stroke rates during follow-up. Cryoablation may reduce AF duration impact on success compared with combined bipolar radiofrequency and cryothermia. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - July 27, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

Anti-NMDA Receptor Encephalitis in a Patient with Previous Psychosis and Neurological Abnormalities: A Diagnostic Challenge.
We present the case of a woman who was followed up at our facility for over 14 years for the treatment of multiple neuropsychiatric symptoms. Initially, she presented with paresthesias, memory loss, and manic symptoms. Nine years later, she presented to our facility again, this time with left sided numbness, left eyelid droop, and word finding difficulties. Finally, five years later, she presented with manic symptoms, hallucinations, and memory impairment. During her hospitalization, she subsequently developed catatonic symptoms and seizures. During her stay, it was discovered that she was positive for anti-NMDA receptor a...
Source: Case Reports in Psychiatry - July 26, 2015 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Alcohol use in bipolar disorder: A neurobiological model to help predict susceptibility, select treatments and attenuate cortical insult
Publication date: September 2015 Source:Neuroscience & Biobehavioral Reviews, Volume 56 Author(s): Kate M. Chitty, Jim Lagopoulos, Ian B. Hickie, Daniel F. Hermens In a series of neurophysiological and neuroimaging studies we investigated the neurobiology related to alcohol use in young people with bipolar disorder. Impairments were identified across frontal and temporal representations of event-related potential and proton magnetic resonance spectroscopy markers; mismatch negativity and in vivo glutathione, respectively. We propose these findings reflect impairments in the N-methyl-d-aspartate receptor and a...
Source: Neuroscience and Biobehavioral Reviews - July 26, 2015 Category: Neuroscience Source Type: research

Synthesis and modification of carbon nanomaterials via AC arc and dielectric barrier discharge plasma
Publication date: 1 January 2016 Source:Chemical Engineering Journal, Volume 283 Author(s): D.L. Sun, R.Y. Hong, F. Wang, J.Y. Liu, M. Rajesh Kumar Combination of preparation and modification of carbon nanomaterials was realized through an attractive technological process based on two kinds of plasma methods in this study. An alternating current (AC) arc discharge plasma method in a fluidized bed had been employed for preparation of carbon nanomaterials with controlled structure, in which propane was cracked into carbon particles (CPs) and carbon nanotubes (CNTs). CPs were modified by using an atmospheric dielectric...
Source: Chemical Engineering Journal - July 26, 2015 Category: Chemistry Source Type: research

Is bipolar disorder associated with accelerating aging? A meta-analysis of telomere length studies.
Bipolar disorder (BD) is associated with a reduced life expectancy compared to the general population mainly due to a high prevalence of comorbid somatic illnesses. A model of accelerated aging has been proposed as a potential explanation to these epidemiological findings. Nevertheless, studies measuring telomere length (TL) in patients with BD compared to healthy controls have provided mixed results. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - July 26, 2015 Category: Neurology Authors: Gabriela D. Colpo, Daniella D. Leffa, Cristiano A. Köhler, Flávio Kapczinski, João Quevedo, André F. Carvalho Source Type: research

The effect of temperament on the treatment adherence of bipolar disorder type I
Nordic Journal of Psychiatry, Ahead of Print. (Source: Nordic Journal of Psychiatry)
Source: Nordic Journal of Psychiatry - July 25, 2015 Category: Psychiatry Tags: article Source Type: research

Circadian rest–activity rhythm in individuals at risk for psychosis and bipolar disorder
At-risk mental states (ARMS) are clinical syndromes that are associated with higher risk, compared with the general population, for developing psychosis and bipolar disorder. Circadian rhythm misalignments have been proposed to be part of this early phase of the clinical course. (Source: Schizophrenia Research)
Source: Schizophrenia Research - July 25, 2015 Category: Psychiatry Authors: Juliana Castro, Marcio Zanini, Bruno da Silva Brandão Gonçalves, Fernando Morgadinho Santos Coelho, Rodrigo Bressan, Lia Bittencourt, Ary Gadelha, Elisa Brietzke, Sergio Tufik Source Type: research

The Bipolarity of light and dark – A review on bipolar disorder and circadian Cycles
The concept of Bipolar Disorder (BD) has been in constant evolution since the Ancient Greece. The official classifications are based on Kraepelin’s perspective of “Manic Depressive Insanity”, but the emphasis has been shifting to the concept of bipolar spectrum, which extends to the limits of normal temperament (Akiskal and Pinto, 1999). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - July 25, 2015 Category: Neurology Authors: T. Abreu, M. Bragança Source Type: research

Neuroanatomical Correlates of genetic risk for bipolar disorder: A voxel-based morphometry study in bipolar type I Patients and healthy first degree Relatives
Bipolar disorder (BD) is a highly heritable mental illness which is associated with neuroanatomical abnormalities. Investigating healthy individuals at high genetic risk for bipolar disorder may help to identify neuroanatomical markers of risk and resilience without the confounding effects of burden of illness or medication. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - July 25, 2015 Category: Neurology Authors: Aybala Sarıçiçek, Nefize Yalın, Ceren Hıdıroğlu, Berrin Çavuşoğlu, Cumhur Taş, Deniz Ceylan, Nabi Zorlu, Emel Ada, Zeliha Tunca, Ayşegül Özerdem Tags: Research report Source Type: research

Electrical Carotid Sinus Stimulation: Chances and Challenges in the Management of Treatment Resistant Arterial Hypertension
Abstract Treatment resistant arterial hypertension is associated with excess cardiovascular morbidity and mortality. Electrical carotid sinus stimulators engaging baroreflex afferent activity have been developed for such patients. Indeed, baroreflex mechanisms contribute to long-term blood pressure control by governing efferent sympathetic and parasympathetic activity. The first-generation carotid sinus stimulator applying bilateral bipolar stimulation reduced blood pressure in a controlled clinical trial but nevertheless failed to meet the primary efficacy endpoint. The second-generation device utilizes smaller ...
Source: Current Hypertension Reports - July 24, 2015 Category: Primary Care Source Type: research

Attempted self-removal of Implanon®: A case report
Publication date: Available online 24 July 2015 Source:Asian Pacific Journal of Reproduction Author(s): Babatunde A. Gbolade A 34-year-old woman with Affective Bipolar Disorder attempted self-removal of an impalpable Implanon® from her arm with a pair of non-sterile implements, resulting in an infected and swollen arm. The device was removed after ultrasound imaging without any complications. This instance is useful for enhancing cognizance of the possibility of self-removal of contraceptive implants and the need for specific follow-up arrangements and timely appointments when a patient requests removal. It also unders...
Source: Asian Pacific Journal of Reproduction - July 24, 2015 Category: Reproduction Medicine Source Type: research

Comparison of Plasma MicroRNA Levels in Drug Naive, First Episode Depressed Patients and Healthy Controls
Publication date: Available online 23 July 2015 Source:Journal of Psychiatric Research Author(s): Mehmet Akif Camkurt, Şenel Acar, Salih Coşkun, Mehmet Güneş, Serkan Güneş, Mehmet Fatih Yılmaz, Ayşegül Görür, Lülüfer Tamer Major depression is the most common psychiatric disorder. The diagnosis of depression depends on a patient’s subjective complaints, and the nature of the heterogeneous disorder. Thus, there is no known biomarker for depression to date. Previous research has indicated that microRNAs are dysregulated in bipolar disorder and schizophrenia. We aimed to investigate microRNA dysregulat...
Source: Journal of Psychiatric Research - July 24, 2015 Category: Psychiatry Source Type: research