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Uptake and intracytoplasmic storage of pigmented particles by human CD34+ stromal cells/telocytes: endocytic property of telocytes
In conclusion, intestinal TCs have a phagocytic‐like property, a function that may be generalized to TCs in other locations. This function (the ability to internalize small particles), together with the capacity of these cells to release extracellular vesicles with macromolecules, could close the cellular bidirectional cooperative circle of informative exchange and intercellular interactions. (Source: Journal of Cellular and Molecular Medicine)
Source: Journal of Cellular and Molecular Medicine - September 30, 2014 Category: Molecular Biology Authors: Lucio Díaz‐Flores, Ricardo Gutiérrez, Mª Pino García, Francisco J. Sáez, Fernando Aparicio, Lucio Díaz‐Flores, Juan F. Madrid Tags: Original Article Source Type: research

Analysis of bipolar and amacrine populations in marmoset retina
This study is a quantitative analysis of cell populations in the inner retina of the New World marmoset monkey using immunohistochemical methods. Marmosets have lower proportions of midget bipolar and rod bipolar cells in comparison to macaque but these differences do not reflect fundamental wiring differences between the two species. (Source: The Journal of Comparative Neurology)
Source: The Journal of Comparative Neurology - September 29, 2014 Category: Neurology Authors: Felix Weltzien, Kumiko A. Percival, Paul R. Martin, Ulrike Grünert Tags: Research Article Source Type: research

U-M, USC, Broad to study genetics of 2 mental health disorders
(University of Michigan) Researchers at the University of Michigan School of Public Health and Medical School and collaborators at two other institutions will undertake the largest whole genome sequencing study funded to date, as they seek to better understand bipolar disorder and schizophrenia. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 29, 2014 Category: Global & Universal Source Type: news

Drift-diffusion simulation of the ephaptic effect in the triad synapse of the retina
Abstract Experimental evidence suggests the existence of a negative feedback pathway between horizontal cells and cone photoreceptors in the outer plexiform layer of the retina that modulates the flow of calcium ions into the synaptic terminals of cones. However, the underlying mechanism for this feedback is controversial and there are currently three competing hypotheses: the ephaptic hypothesis, the pH hypothesis, and the GABA hypothesis. The goal of this investigation is to demonstrate the ephaptic hypothesis by means of detailed numerical simulations. The drift-diffusion (Poisson-Nernst-Planck) model with memb...
Source: Journal of Computational Neuroscience - September 28, 2014 Category: Neuroscience Source Type: research

African-American Women and Depression
Depression is a huge health concern among African Americans — particularly women — but mental health is often stigmatized in the Black community. Although it can impact people from all walks of life, cultural habits and historical experiences can cause depression to be expressed and addressed differently among Black women. “During slavery you were supposed to be the strong one. You weren’t supposed to speak. You were supposed to just do,” said Esney M. Sharpe, founder and CEO of the Bessie Mae Women’s Health Center in East Orange, N.J., which offers health services for uninsured and unde...
Source: Psych Central - September 27, 2014 Category: Psychiatry Authors: Nia Hamm Tags: Depression Disorders General Health Insurance Psychotherapy Treatment Women's Issues African American Black community Black people Gender Differences Stigma Suicide Source Type: news

Fetal growth and psychiatric and socioeconomic problems: population-based sibling comparison.
Conclusions Results suggest that fetal growth, and factors that influence it, contribute to psychiatric and socioeconomic problems. PMID: 25257067 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - September 27, 2014 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Here One Day
A life lived with and lost to bipolar more (Source: Psychology Today Depression Center)
Source: Psychology Today Depression Center - September 27, 2014 Category: Psychiatry & Psychology Authors: Lloyd I. Sederer, M.D. Tags: Depression Psychiatry Relationships Stress Source Type: news

[Comment] Antipsychotics, mood stabilisers, and reductions in violence
In the past 25 years, evidence has accumulated that people with schizophrenia are at increased risk to commit violent crimes and, to a lesser degree, non-violent crimes compared with the general population. A smaller amount of evidence suggests that patients with bipolar disorder are also at increased risk of committing violent offences. Although both disorders are mainly treated with drugs that reduce risk of relapse, the effect of antipsychotic medications and mood stabilisers on violence has been unclear. (Source: LANCET)
Source: LANCET - September 27, 2014 Category: Journals (General) Authors: Sheilagh Hodgins Tags: Comment Source Type: research

Bipolar Medication/Alcohol Interactions Can Be...
Drinking alcohol when you are taking psychiatric medications can cause significant problems. Here is a list of medications and problem interactions. (Source: Bipolar Disorder)
Source: Bipolar Disorder - September 27, 2014 Category: Psychiatry Authors: at Tags: health Source Type: news

Survey Finds Both Benefits and Risks of Yoga for Bipolar Disorder
The information, plus a pilot clinical trial currently underway, could help psychologists develop yoga as an adjunctive therapy for the condition. (Source: Disabled World)
Source: Disabled World - September 26, 2014 Category: Disability Tags: Yoga Source Type: news

The affective dimension of early‐onset psychosis and its relationship with suicide
ConclusionsThe FEP of both SZ and BP is preceded by an identifiable prodromal phase. Early detection programs should target young people at clinical risk for the extended psychosis phenotype. The high prevalence of affective symptoms during the early phases of psychosis may encourage clinicians to identify and treat them in order to prevent suicide behaviour. (Source: Journal of Child Psychology and Psychiatry)
Source: Journal of Child Psychology and Psychiatry - September 26, 2014 Category: Psychiatry Authors: Vanessa Sanchez‐Gistau, Inmaculada Baeza, Celso Arango, Ana González‐Pinto, Elena Serna, Mara Parellada, Montserrat Graell, Beatriz Paya, Cloe Llorente, Josefina Castro‐Fornieles Tags: Original Article Source Type: research

Ideal Bipolar Host Materials with Bis-benzimidazole Unit for Highly Efficient Solution-Processed Green Electrophosphorescent Devices
Organic LettersDOI: 10.1021/ol502531y (Source: Organic Letters)
Source: Organic Letters - September 26, 2014 Category: Chemistry Authors: Wei Jiang, Jinan Tang, Xinxin Ban, Yueming Sun, Lian Duan and Yong Qiu Source Type: research

NICE: Updated bipolar disorder guidance
National Institute of Health and Care Excellence (NICE) has published an updated guidance for diagnosis and management of bipolar disorder Hide related content:  Show related content read more (Source: Nursing in Practice)
Source: Nursing in Practice - September 26, 2014 Category: Nursing Authors: Lalah-Simone Springer Tags: Mental health Editor ' s pick Latest News Source Type: news

A novel photoelectrocatalytic approach for water splitting by an I-BiOCl/bipolar membrane sandwich structure
Green Chem., 2014, Accepted ManuscriptDOI: 10.1039/C4GC01610F, CommunicationXian Liu, Huimin Yang, Hongyan Dai, Xiaoming Mao, Zhenhai LiangA novel photoelectrocatalytic approach for water splitting through I-BiOCl/bipolar membrane sandwich structure with photoelectro-synergistic catalysis is proposed in this study. The I-BiOCl/bipolar membrane sandwich structure could facilitate separation of photoexcited...The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Green Chem. latest articles)
Source: RSC - Green Chem. latest articles - September 26, 2014 Category: Chemistry Authors: Xian Liu Source Type: research

Optimized Multisite Ventricular Pacing in Postoperative Single-Ventricle Patients
Abstract Ventricular dyssynchrony is associated with morbidity and mortality after palliation of a single ventricle. The authors hypothesized that resynchronization with optimized temporary multisite pacing postoperatively would be safe, feasible, and effective. Pacing was assessed in the intensive care unit within the first 24 h after surgery. Two unipolar atrial pacing leads and four bipolar ventricular pacing leads were placed at standardized sites intraoperatively. Pacing was optimized to maximize mean arterial pressure. The protocol tested 11 combinations of the 4 different ventricular lead sites, 6 atriove...
Source: Mammalian Genome - September 26, 2014 Category: Genetics & Stem Cells Source Type: research

Agonist‐dependent and ‐independent dopamine‐1‐like receptor signalling differentially regulates downstream effectors
De‐regulation of energy metabolism by the dopaminergic system is linked to neurological diseases such as schizophrenia and bipolar disorder. Inverse agonists are thought to be more beneficial in treating neurological diseases than neutral antagonists, but only limited experimental data are available regarding the impact of constitutive signalling on energy metabolism. The aim of the present study was to assess the impact of constitutive dopamine‐1 receptor (D1R) and dopamine‐5 receptor (D5R) signalling on downstream targets in transiently and stably transfected HEK293T cells. The high constitutive activity of D5R was...
Source: FEBS Journal - September 26, 2014 Category: Research Authors: Dirk Roosterman Tags: Original Article Source Type: research

Clock gene variants differentiate mood disorders.
Abstract Genetic variations in clock-related genes were hypothesized to be involved to in the susceptibility of mood disorders MD (both unipolar (UPD) and bipolar (BPD) disorders). In our work we investigated role of gene variants form four core period proteins: CLOCK, ARNTL, TIM and PER3. The total sample comprised from 744 mood disorders inpatients (UPD = 229, BPD = 515) and 635 healthy voluntary controls. The 42 SNPs from four genes of interest were genotyped. We used single polymorphisms, haplotypes, SNPs interactions and prediction analysis using classical statistical and machine learning methods. We obser...
Source: Molecular Biology Reports - September 26, 2014 Category: Molecular Biology Authors: Dmitrzak-Weglarz MP, Pawlak JM, Maciukiewicz M, Moczko J, Wilkosc M, Leszczynska-Rodziewicz A, Zaremba D, Hauser J Tags: Mol Biol Rep Source Type: research

Changes in the ERG d-wave with vigabatrin treatment in a pediatric cohort
Conclusions Vigabatrin associated retinal defects may be reflected in reduction of the cone d-wave amplitude. (Source: Documenta Ophthalmologica)
Source: Documenta Ophthalmologica - September 25, 2014 Category: Opthalmology Source Type: research

Evaluation of the Potential for a Pharmacokinetic Drug–Drug Interaction Between Armodafinil and Ziprasidone in Healthy Adults
Conclusion Systemic exposure to ziprasidone was not affected by pretreatment with armodafinil. Both drugs were generally safe and well tolerated under the conditions studied. (Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - September 25, 2014 Category: Drugs & Pharmacology Source Type: research

The developmental trajectory of bipolar disorder.
Authors: Chenard-Poirier MP, Paris J PMID: 25252322 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - September 25, 2014 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Comparative study of cost of care of outpatients with bipolar disorder and schizophrenia.
CONCLUSION: Costs for outpatients with bipolar disorder are similar to the cost of outpatients with schizophrenia. Costs are higher in patients of bipolar disorder with lower level of functioning. Findings of the study suggests that reducing the number of visits to the hospital by providing care at the doorsteps, focusing on reduction of substance use and improving the level of functioning of the patients can reduce the cost of care of bipolar disorder. PMID: 25246322 [PubMed - as supplied by publisher] (Source: Asian Journal of Psychiatry)
Source: Asian Journal of Psychiatry - September 25, 2014 Category: Psychiatry Tags: Asian J Psychiatr Source Type: research

The impact of co-morbid personality disorder on use of psychiatric services and involuntary hospitalization in people with severe mental illness
Conclusions In SMI patients, co-morbidity with PD is robustly associated with both high use of inpatient psychiatric services and an increased likelihood of involuntary hospitalization. Patients with SMI and co-morbid PD are likely to require tailored interventions that target both the underlying personality pathology as well as the Axis I disorder. (Source: Social Psychiatry and Psychiatric Epidemiology)
Source: Social Psychiatry and Psychiatric Epidemiology - September 25, 2014 Category: Psychiatry Source Type: research

Phrenic nerve stimulation in cardiac resynchronization therapy
Abstract In cardiac resynchronization therapy (CRT), the electrical impulse delivered by the left ventricular (LV) lead may incidentally cause phrenic nerve stimulation (PNS). The purpose of this state-of-the-art review is to describe the frequency, risk factors, and clinical consequences of PNS and to present the most recent options to successfully manage PNS. PNS occurs in 2 to 37 % of implanted patients and is not always detected in the supine position during implantation. Lateral and posterior veins are at higher risk of PNS than anterior veins, and apical positions are at higher risk of PNS than basal posit...
Source: Journal of Interventional Cardiac Electrophysiology - September 25, 2014 Category: Cardiology Source Type: research

Anterior petroclinoid fold fenestration: an adjunct to clipping of postero-laterally projecting posterior communicating aneurysms
We describe an efficacious technique utilizing fenestration of the anterior petroclinoid fold to facilitate visualization and clipping of PCoA aneurysms abutting this aspect of the tentorium. Of 86 cases of PCoA aneurysms treated between 2003 and 2013, the technique was used in nine (10.5 %) patients to allow for adequate clipping. A 3 mm fenestration in the anterior petroclinoid ligament is created adjacent and lateral to the anterior clinoid process. This fenestration is then widened into a small wedge corridor by bipolar coagulation. In all cases, the proximal aneurysm neck was visualized after the wedge fenestration....
Source: Neurosurgical Review - September 25, 2014 Category: Neurosurgery Source Type: research

Evaluation of electric field distribution in electromagnetic stimulation of human femoral head
Electromagnetic stimulation is a common therapy used to support bone healing in the case of avascular necrosis of the femoral head. In the present study, we investigated a bipolar induction screw system with an integrated coil. The aim was to analyse the influence of the screw parameters on the electric field distribution in the human femoral head. In addition, three kinds of design parameters (the shape of the screw tip, position of the screw in the femoral head, and size of the screw insulation) were varied. The electric field distribution in the bone was calculated using the finite element software Comsol Multiphysics. ...
Source: Bioelectromagnetics - September 25, 2014 Category: Radiology Authors: Yukun Su, Robert Souffrant, Daniel Kluess, Martin Ellenrieder, Wolfram Mittelmeier, Ursula van Rienen, Rainer Bader Tags: Research Article Source Type: research

National team awarded $16 million NIH grant to study genetics of schizophrenia and bipolar disorder
(University of Southern California - Health Sciences) A multi-institutional team of researchers studying schizophrenia and bipolar disorder has been awarded a $16 million grant from the National Institute of Mental Health to create the most extensive genetic resource to date for these two devastating psychiatric disorders, using data assembled by the University of Southern California. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 25, 2014 Category: Global & Universal Source Type: news

Comparison of pro‐inflammatory cytokines among patients with bipolar disorder and unipolar depression and normal controls
ConclusionsHigher levels of sIL‐6R, CRP, sTNF‐R1, and MCP‐1 were noted in BD than in UD. These results may suggest a more severe inflammatory dysregulation in BD. Further studies are required to investigate whether these cytokines could be biomarkers for affective disorders. (Source: Bipolar Disorders)
Source: Bipolar Disorders - September 25, 2014 Category: Psychiatry Authors: Ya‐Mei Bai, Tung‐Ping Su, Cheng‐Ta Li, Shih‐Jen Tsai, Mu‐Hong Chen, Pei‐Chi Tu, Wen‐Fei Chiou Tags: Original Article Source Type: research

Risk of Misery When Stopping SSRI Antidepressants
Here is a look at the causes and symptoms of SSRI Discontinuation Syndrome, which can occur when a person stops taking or reduces dosage of certain antidepressants. (Source: Bipolar Disorder)
Source: Bipolar Disorder - September 25, 2014 Category: Psychiatry Authors: at Tags: health Source Type: news

Why Should I Suspect Someone is a Sociopath?
In common usage, a sociopath is a person without a conscience, often a criminal, often violent. However, this image is an extreme. More... (Source: Bipolar Disorder)
Source: Bipolar Disorder - September 25, 2014 Category: Psychiatry Authors: at Tags: health Source Type: news

Expansive Moods
One of the criteria for diagnosing a manic or hypomanic episode of bipolar disorder is an expansive mood. (Source: Bipolar Disorder)
Source: Bipolar Disorder - September 25, 2014 Category: Psychiatry Authors: at Tags: health Source Type: news

Synchronization of Isolated Downstates (K-Complexes) May Be Caused by Cortically-Induced Disruption of Thalamic Spindling
In conclusion, we show empirically that KCs can be widespread quasi-synchronous cortical downstates, and demonstrate with the first model of stage 2 NREM sleep a possible mechanism whereby this widespread synchrony may arise. (Source: PLoS Computational Biology)
Source: PLoS Computational Biology - September 25, 2014 Category: Biology Authors: Rachel A. Mak-McCully et al. Source Type: research

TRPM1 Purification and Characterization [Protein Structure and Folding]
Transient receptor potential melastatin-1 (TRPM1) is essential for the light-induced depolarization of retinal ON bipolar cells. TRPM1 likely forms a multimeric channel complex, although almost nothing is known about the structure or subunit composition of channels formed by TRPM1 or any of its close relatives. Recombinant TRPM1 was robustly expressed in insect cells, but only a small fraction was localized to the plasma membrane. Similar intracellular localization was observed when TRPM1 was heterologously expressed in mammalian cells. TRPM1 was affinity-purified from Sf9 cells and complexed with amphipol, followed by det...
Source: Journal of Biological Chemistry - September 25, 2014 Category: Chemistry Authors: Agosto, M. A., Zhang, Z., He, F., Anastassov, I. A., Wright, S. J., McGehee, J., Wensel, T. G. Tags: Signal Transduction Source Type: research

Assessing the Utility of Bipolar Membranes for use in Photoelectrochemical Water-Splitting Cells.
Abstract Membranes are important in water-splitting solar cells because they prevent crossover of hydrogen and oxygen. Here, bipolar membranes (BPMs) were tested as separators in water electrolysis cells. Steady-state membrane and solution resistances, electrode overpotentials, and pH gradients were measured at current densities relevant to solar photoelectrolysis. Under forward bias conditions, electrodialysis of phosphate buffer ions creates a pH gradient across a BPM. Under reverse bias, the BPM can maintain a constant buffer pH on both sides of the cell, but a large membrane potential develops. Thus, the BPM do...
Source: ChemSusChem - September 25, 2014 Category: Chemistry Authors: Vargas-Barbosa NM, Geise GM, Hickner MA, Mallouk TE Tags: ChemSusChem Source Type: research

Offer bipolar adults specific, proven intervention
Carers of those with bipolar disorder need greater support and involvementRelated items from OnMedicaStudy shows extent of genetic overlap in mental illnessesBipolar disease risk four times higher with prenatal flu exposureSelf-help books and websites help in severe depressionMental and physical healthcare should be integratedDepressed patients stick with phone CBT (Source: OnMedica Latest News)
Source: OnMedica Latest News - September 24, 2014 Category: UK Health Source Type: news

Taking or not taking medications: psychiatric treatment perceptions in patients diagnosed with bipolar disorder
Summary What is known and objectiveBipolar disorder is a common and disabling condition. Although its negative impact may be limited in some way by the use of different treatment options, lack of adherence to psychiatric treatment is still an obstacle to overcome. Because there are many factors involved in non‐adherence to treatment, in this study, we sought to examine the subjective aspect of this phenomenon. We analysed perceptions of both the disease and the treatment in a group of patients with bipolar disorder. MethodsWe incorporated a qualitative design that included 50 outpatients diagnosed with bipolar disorder t...
Source: Journal of Clinical Pharmacy and Therapeutics - September 24, 2014 Category: Drugs & Pharmacology Authors: I. Vargas‐Huicochea, L. Huicochea, C. Berlanga, A. Fresán Tags: Original Article Source Type: research

What Are Mood Disorders and What Causes Them?
Mood disorders include depressive disorders, bipolar disorder, and depression, mania/hypomania or mixed symptoms due to a medical condition or substance use. In the last case, the substance can be a medication, alcohol, street drugs or something similar. Here is a brief rundown of each category of mood disorders. (Source: Bipolar Disorder)
Source: Bipolar Disorder - September 23, 2014 Category: Psychiatry Authors: at Tags: health Source Type: news

Infamous Sociopaths – Ted Bundy, Josef...
Ted Bundy, Josef Mengele and Diazien Hossencofft are all sociopaths who became infamous because of their crimes. (Source: Bipolar Disorder)
Source: Bipolar Disorder - September 23, 2014 Category: Psychiatry Authors: at Tags: health Source Type: news

What Is The Cure For Bipolar Disorder?
Can bipolar disorder be cured? Unfortunately the answer is no, but it can be treated. We explore this important mental health question more in the following article. (Source: Bipolar Disorder)
Source: Bipolar Disorder - September 23, 2014 Category: Psychiatry Authors: at Tags: health Source Type: news

Table of Contents
Abstract Analysis: Rise in youth suicide attempts followed FDA's antidepressant warnings Study: No major risk of cardiac defects from antidepressant use in pregnancy Clozapine‐induced pulmonary embolism and aspiration pneumonia Mood stabilizer mitigates risk of manic switch in bipolar disorder Varenicline with bupropion helps smoking abstinence in NRT nonresponders Stimulants for ADHD could have protective effect on suicide Antipsychotics cause particular concern in study of adverse event visits Brain malformation more common among SSRI‐exposed children Varenicline effectiveness improved in combination with NRT Neurost...
Source: The Brown University Psychopharmacology Update - September 22, 2014 Category: Psychiatry Source Type: research

Fashion retailer Joy criticised for 'offensive' bipolar disorder comments on Twitter
Joy has apologised for making "deeply offensive and insensitive" remarks about bipolar disorder online (Source: Telegraph Health)
Source: Telegraph Health - September 22, 2014 Category: Consumer Health News Tags: bipolar disorder Joy boycott Twitter bipolar diorder test joy clothes Source Type: news

Use of Bipolar Membranes for Maintaining Steady-State pH Gradients in Membrane-Supported, Solar-Driven Water Splitting.
Abstract A bipolar membrane can maintain a steady-state pH difference between the sites of oxidation and reduction in membrane-supported, solar-driven water-splitting systems without changing the overall thermodynamics required to split water. A commercially available bipolar membrane that can serve this purpose has been identified, its performance has been evaluated quantitatively, and is demonstrated to meet the requirements for this application. For effective utilization in integrated solar-driven water-splitting systems, such bipolar membranes must, however, be modified to simultaneously optimize their physical...
Source: ChemSusChem - September 22, 2014 Category: Chemistry Authors: McDonald MB, Ardo S, Lewis NS, Freund MS Tags: ChemSusChem Source Type: research

Bipolar Disorder Leads to Poor Online Social Interaction
People with bipolar disorder have difficulties in their offline relationships. Research shows that their online interactions also suffer. They have fewer friends and weaker interactions online, and they have poorer knowledge of appropriate Internet behavior. read more (Source: Psychology Today Relationships Center)
Source: Psychology Today Relationships Center - September 21, 2014 Category: Psychiatry & Psychology Authors: Jennifer Golbeck, Ph.D. Tags: Media Psychiatry Relationships bipolar disorder social networking sites social networks Source Type: news

Significance of borderline personality-spectrum symptoms among adolescents with bipolar disorder - Fonseka TM, Swampillai B, Timmins V, Scavone A, Mitchell R, Collinger KA, Goldstein BI.
BACKGROUND: Little is known regarding correlates of borderline personality-spectrum symptoms (BPSS) among adolescents with bipolar disorder (BP). METHODS: Participants were 90 adolescents, 13-19 years of age, who fulfilled DSM-IV-TR criteria for BP... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - September 21, 2014 Category: Global & Universal Tags: Age: Adolescents Source Type: news

Cementless bipolar hemiarthroplasty for unstable intertrochanteric fractures in octogenarians.
CONCLUSION: Cementless bipolar hemiarthroplasty appears to be a suitable method for the treatment of intertrochanteric fracture in octogenarians. However, stable fixation of the posteromedial fragment is necessary to avoid stem subsidence. PMID: 25230266 [PubMed - in process] (Source: Acta Orthopaedica et Traumatologica Turcica)
Source: Acta Orthopaedica et Traumatologica Turcica - September 20, 2014 Category: Orthopaedics Authors: Kim Y, Moon JK, Hwang KT, Choi IY, Kim YH Tags: Acta Orthop Traumatol Turc Source Type: research

Correlates of psychiatric hospitalization in a clinical sample of Canadian adolescents with bipolar disorder - Shapiro J, Timmins V, Swampillai B, Scavone A, Collinger K, Boulos C, Hatch J, Goldstein BI.
OBJECTIVE: To identify factors associated with psychiatric hospitalization among adolescents with bipolar disorder (BD). METHODS: Participants were 100 adolescents, ages 13-19, who fulfilled DSM-IV criteria for bipolar I disorder [(BD-I), n=26], bi... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - September 20, 2014 Category: Global & Universal Tags: Age: Adolescents Source Type: news

Omega-3 Fish Oils for Bipolar Disorder Treatment
Insights from personal experiences with using Omega-3 fatty acids, found in fish oil and flaxseed oil, as a treatment for bipolar disorder. (Source: Bipolar Disorder)
Source: Bipolar Disorder - September 20, 2014 Category: Psychiatry Authors: at Tags: health Source Type: news

What Is Dysthymic Disorder and What Causes It?
Dysthymia is a hard word to find a definition for - till now. Here is a simple and easy to understand explanation of the term. (Source: Bipolar Disorder)
Source: Bipolar Disorder - September 20, 2014 Category: Psychiatry Authors: at Tags: health Source Type: news

4 People - 4 Types of Depression
We've followed our subjects through the nine categories of symptoms used to evaluate whether a person is having a depressive episode. (Source: Bipolar Disorder)
Source: Bipolar Disorder - September 20, 2014 Category: Psychiatry Authors: at Tags: health Source Type: news

Sleep and Circadian Profiles of Bipolar Disorder: From Chronobiology to Novel Therapeutic Strategies
(Source: Current Psychiatry Reviews)
Source: Current Psychiatry Reviews - September 19, 2014 Category: Psychiatry Authors: Boudebesse, CaroleEtain, BrunoGoldstein, TinaMilhiet, VanessaGermain, AnneHenry, ChantalKupfer, DavidLeboyer, Marion Tags: Articles Source Type: research

Tyrosine 251 at the C‐terminus of neuronal glycoprotein M6a is critical for neurite outgrowth
We examined whether phosphorylation of M6a at Y251 affects neurite and filopodia outgrowth and the targets involved in its signal propagation. This work provides evidence that the Src kinase family and the phosphatidylinositide 3‐kinase (PI3K), but not Ras, participate in M6a signal cascade leading to neurite/filopodia outgrowth in hippocampal neurons and murine neuroblastoma N2a cells. Phosphorylation of M6a at Y251 is essential only for neurite outgrowth by the PI3K/AKT‐mediated pathway and, moreover, rescues the inhibition caused by selective Src inhibitor and external M6a monoclonal antibody treatment. Thus, we sug...
Source: Journal of Neuroscience Research - September 19, 2014 Category: Neuroscience Authors: Karina Formoso, Silvia C. Billi, Alberto C. Frasch, Camila Scorticati Tags: Research Article Source Type: research