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Significance of borderline personality-spectrum symptoms among adolescents with bipolar disorder - Fonseka TM, Swampillai B, Timmins V, Scavone A, Mitchell R, Collinger KA, Goldstein BI.
BACKGROUND: Little is known regarding correlates of borderline personality-spectrum symptoms (BPSS) among adolescents with bipolar disorder (BP). METHODS: Participants were 90 adolescents, 13-19 years of age, who fulfilled DSM-IV-TR criteria for BP... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - September 21, 2014 Category: Global & Universal Tags: Age: Adolescents Source Type: news

Cementless bipolar hemiarthroplasty for unstable intertrochanteric fractures in octogenarians.
CONCLUSION: Cementless bipolar hemiarthroplasty appears to be a suitable method for the treatment of intertrochanteric fracture in octogenarians. However, stable fixation of the posteromedial fragment is necessary to avoid stem subsidence. PMID: 25230266 [PubMed - in process] (Source: Acta Orthopaedica et Traumatologica Turcica)
Source: Acta Orthopaedica et Traumatologica Turcica - September 20, 2014 Category: Orthopaedics Authors: Kim Y, Moon JK, Hwang KT, Choi IY, Kim YH Tags: Acta Orthop Traumatol Turc Source Type: research

Correlates of psychiatric hospitalization in a clinical sample of Canadian adolescents with bipolar disorder - Shapiro J, Timmins V, Swampillai B, Scavone A, Collinger K, Boulos C, Hatch J, Goldstein BI.
OBJECTIVE: To identify factors associated with psychiatric hospitalization among adolescents with bipolar disorder (BD). METHODS: Participants were 100 adolescents, ages 13-19, who fulfilled DSM-IV criteria for bipolar I disorder [(BD-I), n=26], bi... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - September 20, 2014 Category: Global & Universal Tags: Age: Adolescents Source Type: news

Omega-3 Fish Oils for Bipolar Disorder Treatment
Insights from personal experiences with using Omega-3 fatty acids, found in fish oil and flaxseed oil, as a treatment for bipolar disorder. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - September 20, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

What Is Dysthymic Disorder and What Causes It?
Dysthymia is a hard word to find a definition for - till now. Here is a simple and easy to understand explanation of the term. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - September 20, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

4 People - 4 Types of Depression
We've followed our subjects through the nine categories of symptoms used to evaluate whether a person is having a depressive episode. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - September 20, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Sleep and Circadian Profiles of Bipolar Disorder: From Chronobiology to Novel Therapeutic Strategies
(Source: Current Psychiatry Reviews)
Source: Current Psychiatry Reviews - September 19, 2014 Category: Psychiatry Authors: Boudebesse, CaroleEtain, BrunoGoldstein, TinaMilhiet, VanessaGermain, AnneHenry, ChantalKupfer, DavidLeboyer, Marion Tags: Articles Source Type: research

Tyrosine 251 at the C‐terminus of neuronal glycoprotein M6a is critical for neurite outgrowth
We examined whether phosphorylation of M6a at Y251 affects neurite and filopodia outgrowth and the targets involved in its signal propagation. This work provides evidence that the Src kinase family and the phosphatidylinositide 3‐kinase (PI3K), but not Ras, participate in M6a signal cascade leading to neurite/filopodia outgrowth in hippocampal neurons and murine neuroblastoma N2a cells. Phosphorylation of M6a at Y251 is essential only for neurite outgrowth by the PI3K/AKT‐mediated pathway and, moreover, rescues the inhibition caused by selective Src inhibitor and external M6a monoclonal antibody treatment. Thus, we sug...
Source: Journal of Neuroscience Research - September 19, 2014 Category: Neuroscience Authors: Karina Formoso, Silvia C. Billi, Alberto C. Frasch, Camila Scorticati Tags: Research Article Source Type: research

[Mania with Psychotic Feature Induced by the use of Pramipexole in Parkinson's Disease: A Case Report].
Abstract Parkinson's disease, a neurodegenerative disorder characterized by movement abnormalities, is frequently complicated by psychiatric syndromes. Psychiatric symptoms may be the direct result of PD, its co-morbid pathologies, or occur as a side effect of its pharmacotherapy. Pramipexole, like other dopamine agonists for treating Parkinson's disease , has a tendency to induce psychotic and manic symptoms due to central dopaminergic stimulation. In this article, mania with psychotic feature induced by the use of dopamine agonists which is not observed frequently in the literature will be discussed. PMID: 2...
Source: Turkish Journal of Psychiatry - September 19, 2014 Category: Psychiatry Authors: Meriç C, Pirdoğan E, Günday Toker O, Tekin A, Bakım B, Celik S Tags: Turk Psikiyatri Derg Source Type: research

[The effect of the sociodemographic and the socioeconomic factors on criminal behavior of male patients with a bipolar I disorder].
CONCLUSION: The findings demonstrate the relationship between sociodemographic and socioeconomic factors and criminal behavior in male patients with a bipolar I disorder. To protect both the patient and the society, these factors are of importance and they should be taken into account by both juridical and psychiatric institutions. PMID: 25219690 [PubMed - in process] (Source: Turkish Journal of Psychiatry)
Source: Turkish Journal of Psychiatry - September 19, 2014 Category: Psychiatry Authors: Camcıoğlu TH, Oncü F, Süküroğlu S, Ger MC, Uygur N Tags: Turk Psikiyatri Derg Source Type: research

[Temperament and character personality dimensions in patients with bipolar I disorder].
CONCLUSION: The personality profiles of the BP-I patients differed from those of the controls. Lower self-directedness and cooperativeness scores in the bipolar group appeared to be associated with more immature personality traits. PMID: 25219688 [PubMed - in process] (Source: Turkish Journal of Psychiatry)
Source: Turkish Journal of Psychiatry - September 19, 2014 Category: Psychiatry Authors: Fayyazi Bordbar MR, Faridhosseini F, Kaviani H, Kazemian M, Samari AA, Kashani Lotfabadi M Tags: Turk Psikiyatri Derg Source Type: research

[Pulmonary embolism in an acute manic patient following physical restraint].
We present a case-study in which a patient developed a pulmonary embolism after being immobilised after a short period while subjected to physical restraint. We discuss the risk factors involved and stress the need for research into the prevention of such incidents. PMID: 25222099 [PubMed - in process] (Source: Tijdschrift voor Psychiatrie)
Source: Tijdschrift voor Psychiatrie - September 19, 2014 Category: Psychiatry Authors: Pirsoul S, De Backer L, Schrijvers D Tags: Tijdschr Psychiatr Source Type: research

Super‐resolution reconstruction of late gadolinium‐enhanced MRI for improved myocardial scar assessment
ConclusionWe propose an SRR method to automatically reconstruct a high‐quality isotropic LGE volume from three orthogonal views. Analysis of the in vivo EAVM demonstrated improved myocardial scar assessment from the SRR volume compared with the SA LGE alone. J. Magn. Reson. Imaging 2014. © 2014 Wiley Periodicals, Inc. (Source: Journal of Magnetic Resonance Imaging)
Source: Journal of Magnetic Resonance Imaging - September 19, 2014 Category: Radiology Authors: Oleh Dzyubachyk, Qian Tao, Dirk H.J. Poot, Hildo J. Lamb, Katja Zeppenfeld, Boudewijn P.F. Lelieveldt, Rob J. van der Geest Tags: Original Research Source Type: research

The clinical experience and efficacy of bipolar radiofrequency with fractional photothermolysis for aged Asian skin
The objective evaluation in each category showed significant improvements in the wrinkles on the lateral canthus (crow's feet) and lower eyelid. As for the nasolabial fold, 60% of the subjects showed improvements, scoring from good to excellent (51–100% improvement), although there was a little improvement of the wrinkle on the forehead. Similar improvements were observed in the subjective evaluation. During each treatment, oedema and erythema were observed in all participants, but the oedema disappeared the following day in all cases. However, mild erythema persisted for an average of 3.1 days. Micro debris disappeared...
Source: Experimental Dermatology - September 19, 2014 Category: Dermatology Authors: Hirotaka Akita, Ryosuke Sasaki, Yusuke Yokoyama, Kei Negishi, Kayoko Matsunaga Tags: Original Article Source Type: research

Reactive retinal microglia, neuronal survival, and the formation of retinal folds and detachments
Reactive microglia and macrophages are prevalent in damaged retinas. Accordingly, we investigate how the activation or ablation of microglia/macrophages influences the survival of neurons in the chick retina in vivo. We applied intraocular injections of interleukin 6 (IL6) to stimulate the reactivity of microglia/macrophages and clodronate‐liposomes to ablate microglia/macrophages. Activation of the microglia/macrophages with IL6 delays the death of retinal neurons from N‐methyl‐D‐aspartate (NMDA) ‐induced excitotoxicity. In addition, activation of microglia/macrophages combined with colchicine‐mediated retinal...
Source: Glia - September 18, 2014 Category: Neurology Authors: Andy J. Fischer, Christopher Zelinka, Nima Milani‐Nejad Tags: Research Article Source Type: research

What if the Central Premise of Bipolar Disorder Is Wrong?
Always appending disorder to the word bipolar is akin to always appending accident to the end of automobile. In other words, saying “bipolar disorder” is the same as saying “car accident” every time you mention a car. read more (Source: Psychology Today Depression Center)
Source: Psychology Today Depression Center - September 18, 2014 Category: Psychiatry & Psychology Authors: Tom Wootton Tags: Depression Psychiatry Resilience Self-Help bipolar disorder Bipolar in order mania Tom Wootton Source Type: news

The ‐116C/G polymorphism in XBP1 gene is associated with psychiatric illness in Asian population: A meta‐analysis
X‐box binding protein 1 (XBP1) is a pivotal transcription factor and plays an important role in the pathogenesis of psychiatric illness. The association between XBP1 ‐116C/G polymorphism and risk of psychiatric illness has been investigated in different populations. However, the results of these studies remain conflicting. Therefore, we performed a systematic meta‐analysis to evaluate the association between XBP1 ‐116C/G polymorphism and the overall psychiatric illness risk. Pubmed, Embase, and Chinese Biomedical Literature Database (CBM) were searched for case‐control studies on the association between XBP1 ‐1...
Source: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics - September 18, 2014 Category: Genetics & Stem Cells Authors: Dan Cheng, Kan Zhang, Guohua Zhen, Zheng Xue Tags: Research Article Source Type: research

Suicide, hospital-presenting suicide attempts, and criminality in bipolar disorder: examination of risk for multiple adverse outcomes - Webb RT, Lichtenstein P, Larsson H, Geddes JR, Fazel S.
OBJECTIVE: To compare risks for suicidality and criminality in a national cohort of people diagnosed with bipolar disorder, and to assess how risk factor profiles differ between these outcomes. METHOD: We conducted 2 case-cohort studies using inter... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - September 18, 2014 Category: Global & Universal Tags: Suicide and Self-Harm Source Type: news

Open angle glaucoma in a case of Type IV Ehler Danlos syndrome: A rarely reported association
Arijit Mitra, R Ramakrishnan, Mohideen Abdul KaderIndian Journal of Ophthalmology 2014 62(8):880-884A 26-year-old male presented to us with defective vision in the left eye. He had best corrected visual acuity (BCVA) of hand movement (HM) in right eye and 6/9 in left eye. He had ptosis with ectropion in both eyes and relative afferent pupillary defect (RAPD) in right eye. Intraocular pressure (IOP) was 46 and 44 mmHg in right and left eye, respectively. Fundus showed glaucomatous optic atrophy (GOA) in right eye and cup disc ratio (CDR) of 0.75 with bipolar rim thinning in left eye. Systemic examination showed hyperextensi...
Source: Indian Journal of Ophthalmology - September 18, 2014 Category: Opthalmology Authors: Arijit MitraR RamakrishnanMohideen Abdul Kader Source Type: research

Bipolars and Internet Romance
People with bipolar disorder may be especially vulnerable to the hazards of online relationships - Part 1 of 3. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - September 18, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

My Father Has Bipolar Disorder - And It's Rough...
A young teenager gives her perspective on her father's bipolar disorder, from the ways he has helped her understand the highs and lows to how she feels about his suicide attempts. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - September 18, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

A Ready to Use Basic Psychopharmacology Didactic Curriculum: Treatment of Depression, Anxiety, and ADHD (Yvonne Murphy MD)
Fully developed collection of teaching sessions focused on the pharmacologic treatment of depression, anxiety, and ADHD with an additional resource for Bipolar Disorder. This curriculum is meant to augment teaching on identification and behavioral therapies for these common primary care disorders and focuses specifically on medication selection and use. Materials are appropriate for students, residents, and other primary care providers for either large or small groups. (Source: Family Medicine Digital Resources Library (FMDRL) Recently Uploaded)
Source: Family Medicine Digital Resources Library (FMDRL) Recently Uploaded - September 18, 2014 Category: Primary Care Source Type: news

Benefits, risks of yoga found for bipolar disorder
A survey of people with bipolar disorder who practice yoga have identified benefits and risks of the practice. The information, plus a pilot clinical trial currently underway, could help psychologists develop yoga as an adjunctive therapy for the condition. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 17, 2014 Category: Science Source Type: news

Yoga may help people with bipolar disorder, reports Journal of Psychiatric Practice
(Wolters Kluwer Health) People with bipolar disorder who do yoga believe their yoga practice has significant mental health benefits, reports a survey study in the Sept. Journal of Psychiatric Practice. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 17, 2014 Category: Global & Universal Source Type: news

Survey finds benefits, risks of yoga for bipolar disorder
(Brown University) Newly published results from a survey of people with bipolar disorder who practice yoga have begun to document the reported benefits and risks of the practice. The information, plus a pilot clinical trial currently underway, could help psychologists develop yoga as an adjunctive therapy for the condition. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - September 17, 2014 Category: Global & Universal Source Type: news

Hybrid approach to atrial fibrillation ablation using bipolar radiofrequency devices epicardially and cryoballoon endocardially
CONCLUSIONS A hybrid approach to AF ablation using a cryoballoon endocardially and a bipolar RF device epicardially is feasible and safe. (Source: Interactive CardioVascular and Thoracic Surgery)
Source: Interactive CardioVascular and Thoracic Surgery - September 17, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Kumar, N., Pison, L., La Meir, M., Maessen, J., Crijns, H. J. Tags: Pleura, Myocardial infarction ADULT CARDIAC Source Type: research

The use of an electrothermal bipolar tissue sealing system in the management of lung hydatid disease
Surgery is the treatment of choice for management of pulmonary hydatid cysts. Total pericystectomy provided the best results concerning the recurrence of the disease, but haemorrhagia and air leak during dissection of the pericystic space are the main disadvantages of such a method. To avoid these complications, we proposed the use of an electrothermal bipolar tissue sealing system. After the extraction of the hydatid cyst, a small space is created between the pericyst and normal lung, and the separation between the two zones is joined using the electrothermal bipolar tissue sealing system. This procedure reduces the risk ...
Source: Interactive CardioVascular and Thoracic Surgery - September 17, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Santini, M., Fiorelli, A., Milione, R., Vicidomini, G., Accardo, M. Tags: Pleura THORACIC Source Type: research

Hypoactivation of the Ventral and Dorsal Striatum During Reward and Loss Anticipation in Antipsychotic and Mood Stabilizer-Naive Bipolar Disorder
M Goodwin Keywords: (Source: Neuropsychopharmacology)
Source: Neuropsychopharmacology - September 17, 2014 Category: Neurology Authors: Sarah W YipPatrick D WorhunskyRobert D RogersGuy M Goodwin Source Type: research

Dysfunction of emotional brain systems in individuals at high risk of mood disorder with depression and predictive features prior to illness.
CONCLUSIONS: These findings suggest evidence for specific changes related to the presence of illness and evidence that changes in brain function in cortico-thalamic-limbic regions precede clinical illness. PMID: 25229638 [PubMed - as supplied by publisher] (Source: Psychological Medicine)
Source: Psychological Medicine - September 17, 2014 Category: Psychiatry Authors: Whalley HC, Sussmann JE, Romaniuk L, Stewart T, Kielty S, Lawrie SM, Hall J, McIntosh AM Tags: Psychol Med Source Type: research

Bipolar Disorder in Youth Not as Chronic as ThoughtBipolar Disorder in Youth Not as Chronic as Thought
A long-term study of bipolar disorder shows as many as one quarter of youths remain largely well across the course of 8 years. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 16, 2014 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Medications for Bipolar Disorder - Overview
Medications are the standard treatment for bipolar disorder. Sometimes a single prescription drug is enough, but more often a combination is needed. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - September 16, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

The serotonin transporter genotype modulates the relationship between early stress and adult suicidality in bipolar disorder
Conclusions5‐HTTLPR modulated the relationship between early life stress and the core features of bipolar illness. 5‐HTTLPR*s carriers showed a higher sensitivity to the effects of stress; when exposed to low levels of early stress, they were protected against suicide in respect to l/l, but higher levels of stress progressively increased their risk of suicide and reduced the age at onset of illness. (Source: Bipolar Disorders)
Source: Bipolar Disorders - September 15, 2014 Category: Psychiatry Authors: Francesco Benedetti, Roberta Riccaboni, Sara Poletti, Daniele Radaelli, Clara Locatelli, Cristina Lorenzi, Adele Pirovano, Enrico Smeraldi, Cristina Colombo Tags: Original Article Source Type: research

A genetic analysis of the validity of the Hypomanic Personality Scale
ConclusionsThese results provide additional support for the validity of the Hypomanic Personality Scale. (Source: Bipolar Disorders)
Source: Bipolar Disorders - September 15, 2014 Category: Psychiatry Authors: Sheri L Johnson, Charles S Carver, Jutta Joormann, Michael Cuccaro Tags: Original Article Source Type: research

Changes of cortical excitability as markers of antidepressant response in bipolar depression: preliminary data obtained by combining transcranial magnetic stimulation (TMS) and electroencephalography (EEG)
ConclusionsChanges in measures of cortical excitability parallel and predict antidepressant response to combined sleep deprivation and light therapy. Data suggest that promoting cortical plasticity in bipolar depression could be a major effect of successful antidepressant treatments, and that patients not responding could suffer a persistent impairment in their neuroplasticity mechanisms. (Source: Bipolar Disorders)
Source: Bipolar Disorders - September 15, 2014 Category: Psychiatry Authors: Paola Canali, Giovanna Sferrazza Papa, Adenauer G Casali, Giandomenico Schiena, Matteo Fecchio, Andrea Pigorini, Enrico Smeraldi, Cristina Colombo, Francesco Benedetti Tags: Original Article Source Type: research

EEG mean frequency changes in healthy subjects during prefrontal transcranial direct current stimulation
In this pilot study we evaluated electroencephalographic (EEG) mean frequency changes induced by prefrontal transcranial direct current stimulation (tDCS) and investigated whether they depended on tDCS electrode montage. Eight healthy volunteers underwent tDCS for 15 min during EEG recording. They completed six tDCS sessions, 1 wk apart, testing left and right direct current (DC) dipole directions with six different montages: four unipolar montages (one electrode on a prefrontal area, the other on the opposite wrist) and two bipolar montages (both electrodes on prefrontal areas), and a single sham session. EEG power spectr...
Source: Journal of Neurophysiology - September 15, 2014 Category: Neurology Authors: Accornero, N., Capozza, M., Pieroni, L., Pro, S., Davi, L., Mecarelli, O. Tags: Higher Neural Functions and Behavior Source Type: research

Intrinsic bursting of AII amacrine cells underlies oscillations in the rd1 mouse retina
In many forms of retinal degeneration, photoreceptors die but inner retinal circuits remain intact. In the rd1 mouse, an established model for blinding retinal diseases, spontaneous activity in the coupled network of AII amacrine and ON cone bipolar cells leads to rhythmic bursting of ganglion cells. Since such activity could impair retinal and/or cortical responses to restored photoreceptor function, understanding its nature is important for developing treatments of retinal pathologies. Here we analyzed a compartmental model of the wild-type mouse AII amacrine cell to predict that the cell's intrinsic membrane properties,...
Source: Journal of Neurophysiology - September 15, 2014 Category: Neurology Authors: Choi, H., Zhang, L., Cembrowski, M. S., Sabottke, C. F., Markowitz, A. L., Butts, D. A., Kath, W. L., Singer, J. H., Riecke, H. Tags: Cellular and Molecular Properties Of Neurons Source Type: research

Treatment-Resistant Bipolar Depression: A Randomized Controlled Trial of Electroconvulsive Therapy Versus Algorithm-Based Pharmacological Treatment.
Conclusion: Remission rates remained modest regardless of treatment choice for this challenging clinical condition. PMID: 25219389 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - September 15, 2014 Category: Psychiatry Authors: Schoeyen HK, Kessler U, Andreassen OA, Auestad BH, Bergsholm P, Malt UF, Morken G, Oedegaard KJ, Vaaler A Tags: Am J Psychiatry Source Type: research

What Causes Emotional Pain In Bipolar Disorder?
This article examines those symptoms and discusses how they are different from those of situational depression. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - September 14, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Recovery-focused cognitive-behavioural therapy for recent-onset bipolar disorder: randomised controlled pilot trial.
Conclusions Recovery-focused CBT seems promising with respect to feasibility and potential clinical effectiveness. Clinical- and cost-effectiveness now need to be reliably estimated in a definitive trial. PMID: 25213157 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - September 13, 2014 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Functional impairment in adolescents and young adults with emerging mood disorders.
Conclusions Levels of disability were significant, even in those presenting for mental healthcare for the first time. Functional impairment did not differ between unipolar and bipolar cases, but some evidence suggested that females with bipolar disorder were particularly disabled. The prevalence of comorbid disorders (50%) and polysubstance use (28%) and their association with disability indicate that more meaningful indicators of mood episode outcomes should focus on functional rather than symptom-specific measures. The association between functioning and nicotine use requires further exploration. PMID: 25213156 [PubM...
Source: The British Journal of Psychiatry for Mental Science - September 13, 2014 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Probabilistic map of critical functional regions of the human cerebral cortex: Broca's area revisited
We report the first bilateral probabilistic map for crucial cortical epicentres of human brain functions in the right and left hemispheres, including sensory, motor, and language (speech, articulation, phonology and semantics). These data challenge classical theories of brain organization (e.g. Broca’s area as speech output region) and provide a distributed framework for future studies of neural networks. (Source: Brain)
Source: Brain - September 13, 2014 Category: Neurology Authors: Tate, M. C., Herbet, G., Moritz-Gasser, S., Tate, J. E., Duffau, H. Tags: Original Articles Source Type: research

Kleine-Levin Syndrome May Be Misdiagnosed as...
This rare disorder shares many symptoms with bipolar, and thus a correct diagnosis of Kleine-Levin Syndrome may be delayed. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - September 13, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

How Much Social Security Disability Will You...
Part 9 of Understanding Disability Benefits. In considering disability, an important question that always arises is the value of the disability benefits that will be provided if your application is successful. Given the cost in time and frustration, is the return worth the investment? The answer to these questions will greatly depend on your specific circumstances. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - September 13, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Fewer CRT-Lead-Related Complications With Quadripolar Vs Bipolar Leads: MORE CRT TrialFewer CRT-Lead-Related Complications With Quadripolar Vs Bipolar Leads: MORE CRT Trial
In a rare randomized comparison of pacemaker leads, using quadripolar instead of bipolar leads cut the risk of intra- and postprocedure lead-related complications by about 40%. Heartwire (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 12, 2014 Category: Consumer Health News Tags: Cardiology News Source Type: news

Two For: Memories of a Manic Father
A shopping spree. Retail therapy. The high of a manic episode. Call it what you will, an out-of-control buying binge, especially one with a credit card in hand, is a very dangerous thing. My father was what we then called “manic-depressive.’” Nowadays, his condition would be called “bipolar disorder.” I don’t care what it’s called. It ruined my childhood. My mother died of ovarian cancer when I was 12, just as I was entering puberty. I wasn’t allowed to see her for the last two weeks of her life, nor was I told she was dying, even though she had been ill since I was 4. Other moms did things ...
Source: Psych Central - September 12, 2014 Category: Psychiatry Authors: Lorna Evans Tags: Abuse Anger Bipolar Children and Teens Disabilities Family General Grief and Loss Parenting Personal Stories Bipolar Disorder Cancer Death Of A Parent Emotional Abuse Lithium mania Spending Spree Source Type: news

A genome‐wide supported psychiatric risk variant in NCAN influences brain function and cognitive performance in healthy subjects
Abstract The A allele of the single nucleotide polymorphism (SNP) rs1064395 in the NCAN gene has recently been identified as a susceptibility factor for bipolar disorder and schizophrenia. NCAN encodes neurocan, a brain‐specific chondroitin sulfate proteoglycan that is thought to influence neuronal adhesion and migration. Several lines of research suggest an impact of NCAN on neurocognitive functioning. In the present study, we investigated the effects of rs1064395 genotype on neural processing and cognitive performance in healthy subjects. Brain activity was measured with functional magnetic resonance imaging (fMRI) dur...
Source: Human Brain Mapping - September 12, 2014 Category: Neurology Authors: Heidelore Raum, Bruno Dietsche, Arne Nagels, Stephanie H. Witt, Marcella Rietschel, Tilo Kircher, Axel Krug Tags: Research Article Source Type: research

Impact of socioeconomic deprivation on rate and cause of death in severe mental illness
Background: Socioeconomic status has important associations with disease-specific mortality in the general population. Although individuals with Severe Mental Illnesses (SMI) experience significant premature mortality, the relationship between socioeconomic status and mortality in this group remains under investigated. We aimed to assess the impact of socioeconomic status on rate and cause of death in individuals with SMI (schizophrenia and bipolar disorder) relative to the local (Glasgow) and wider (Scottish) populations. Methods: Cause and age of death during 2006-2010 inclusive for individuals with schizophrenia or bipo...
Source: BMC Psychiatry - Latest articles - September 12, 2014 Category: Psychiatry Authors: Julie Langan MartinGary McLeanJohn ParkDaniel MartinMoira ConnollyStewart MercerDaniel Smith Source Type: research

NMDA and AMPA receptors contribute similarly to temporal processing in mammalian retinal ganglion cells.
This article is protected by copyright. All rights reserved. PMID: 25217374 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - September 12, 2014 Category: Physiology Authors: Stafford BK, Manookin MB, Singer JH, Demb JB Tags: J Physiol Source Type: research

Inner retinal preservation in rat models of retinal degeneration implanted with subretinal photovoltaic arrays.
In this study, we used immunohistochemical methods to qualitatively and quantitatively compare inner retinal morphology after the implantation of a PVA in two RP models: the Royal College of Surgeons (RCS) or transgenic S334ter-line 3 (S334ter-3) rhodopsin mutant rat. Two PVA designs were compared. In the RCS rat, we implanted devices in the subretinal space at 4 weeks of age and histologically examined them at 8 weeks of age and found inner retinal morphology preservation with both PVA devices. In the S334ter-3 rat, we implanted devices at 6 to 12 weeks of age and again, inner retinal morphology was generally preserved wi...
Source: Experimental Eye Research - September 12, 2014 Category: Opthalmology Authors: Light JG, Fransen JW, Adekunle AN, Adkins A, Pangeni G, Loudin J, Mathieson K, Palanker DV, McCall MA, Pardue MT Tags: Exp Eye Res Source Type: research

Adverse childhood experiences worsen cognitive distortion during adult bipolar depression - Poletti S, Colombo C, Benedetti F.
BACKGROUND: Cognitive distortion is a central feature of depression, encompassing negative thinking, dysfunctional personality styles and dysfunctional attitudes. It has been hypothesized that ACEs could increase the vulnerability to depression by contribu... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - September 11, 2014 Category: Global & Universal Tags: Age: Adolescents Source Type: news