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Interstitial Lung Disease in Coppersmiths in High Serum Copper Levels.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Coppersmith is a worker who uses copper most commonly for the production of kitchen appliances in Turkey. This is an ancient occupation practiced for centuries in Turkey. Our objective was to investigate the prevalence of parenchymal lung diseases among coppersmiths in Kahramanmaras city in Turkey. Thirty coppersmiths were included to the study, and they all signed an informed consent. Demographics, spirometric test results and high-resolution computed tomography (HRCT) scans, and blood samples were obtained. Laboratory analysis of the serum samples showed that serum copper levels of the subjects were 0.93 +/- 0.14 mg/...
Source: Biological Trace Element Research - November 17, 2009 Category: Biology Authors: Dagli CE, Tanrikulu AC, Koksal N, Abakay A, Gelen ME, Demirpolat G, Yuksel M, Atilla N, Tolun FI Tags: Biol Trace Elem Res Source Type: journals

Timing of bronchiolitis hospitalisations and respiratory syncytial virus immunoprophylaxis in non-metropolitan Western Australia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19912095 [PubMed - in process] (Source: Med J Aust)
Source: Med J Aust - November 16, 2009 Category: Journals (General) Authors: Moore HC, Keil AD, Richmond PC, Lehmann D Tags: Med J Aust Source Type: journals

Impact of Palivizumab on RSV Hospitalizations for Children with Hemodynamically Significant Congenital Heart DiseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this study was to evaluate the impact of palivizumab prophylaxis on respiratory syncytial virus (RSV) hospitalizations among children with hemodynamically significant congenital heart disease (CHD). In 2003, the American Academy of Pediatrics (AAP) revised the bronchiolitis policy statement and recommended the use of palivizumab in children <24 months old with hemodynamically significant CHD (HS-CHD). California statewide hospital discharge data from years 2000–2002 (pre-AAP policy revision) were compared to those from years 2004–2006 (post-AAP policy revision). Hospitalizations due to...
Source: Pediatric Cardiology - November 14, 2009 Category: Cardiology Tags: Pediatric Cardiology Source Type: journals

Pediatric obstructive sleep apnea: A potential late consequence of respiratory syncitial virus bronchiolitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To examine the hypothesis that children who suffered from severe respiratory syncitial virus (RSV) bronchiolitis during infancy may be at higher risk for obstructive sleep apnea (OSA) later in childhood.Survey of Kosair Children's Hospital medical records allowed for identification of potential candidates for the study. Twenty-one randomly selected children (mean age ± SD: 5.2 ± 1.5 years) with a history of verified RSV-induced bronchiolitis during their first year of life underwent overnight sleep study (NPSG). Children recruited from the general population with no history of RSV bronchiolitis served as a control group....
Source: Pediatric Pulmonology - November 13, 2009 Category: Respiratory Medicine Authors: Ayelet Snow, Ehab Dayyat, Hawley E. Montgomery-Downs, Leila Kheirandish-Gozal, David Gozal Source Type: journals

Semi-Markov Models with Phase-Type Sojourn DistributionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Continuous-time multistate models are widely used for categorical response data, particularly in the modeling of chronic diseases. However, inference is difficult when the process is only observed at discrete time points, with no information about the times or types of events between observation times, unless a Markov assumption is made. This assumption can be limiting as rates of transition between disease states might instead depend on the time since entry into the current state. Such a formulation results in a semi-Markov model. We show that the computational problems associated with fitting semi-Markov models to panel-...
Source: Biometrics - November 13, 2009 Category: Biotechnology Authors: Andrew C. Titman, Linda D. Sharples Source Type: journals

Air Pollution Increases Infants' Risk Of BronchiolitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Infants who are exposed to higher levels of air pollution are at increased risk for bronchiolitis, according to a new study. The study appears in the November 15 issue of the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. "There has been very little study of the consequences of early life exposure to air pollution," said Catherine Karr, M.D. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 11, 2009 Category: Consumer Health News Tags: Respiratory / Asthma Source Type: news

Air Pollution Increases Infants' Risk Of BronchiolitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Infants who are exposed to higher levels of air pollution are at increased risk for bronchiolitis, according to a new study. The study appears in the November 15 issue of the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. "There has been very little study of the consequences of early life exposure to air pollution," said Catherine Karr, M.D. (Source: Water Quality / Air Quality News From Medical News Today)
Source: Water Quality / Air Quality News From Medical News Today - November 11, 2009 Category: Nutrition Tags: Respiratory / Asthma Source Type: news

Pollutants May Increase Bronchiolitis Risk in InfantsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Certain types of traffic-related air pollutants may raise the risk of bronchiolitis in infants, according to research published in the Nov. 15 issue of the American Journal of Respiratory and Critical Care Medicine. (Source: Modern Medicine)
Source: Modern Medicine - November 9, 2009 Category: Journals (General) Source Type: info

Granulomatous-lymphocytic interstitial lung disease (GLILD) in common variable immunodeficiency (CVID).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Infectious complications of the lung occur quite frequently in patients with common variable immunodeficiency (CVID), a clinical syndrome that represents a primary immunodeficiency. However, there appears to be noninfectious pulmonary complications in association with CVID as well, and recently the term granulomatous-lymphocytic interstitial lung disease (GLILD) has been created to describe these noninfectious, diffuse lung disease complications that develop in CVID patients. They exhibit both granulomatous and lymphoproliferative histologic patterns, consisting of lymphocytic interstitial pneumonia (LIP), follicular b...
Source: Clinical Immunology - November 7, 2009 Category: Allergy & Immunology Authors: Park JH, Levinson AI Tags: Clin Immunol Source Type: journals

Wood Fires Can Harm the Youngest LungsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Exposed infants more susceptible to bronchiolitis, study finds (Source: Forbes.com Health News)
Source: Forbes.com Health News - November 6, 2009 Category: Consumer Health News Source Type: news

Wood Fires Can Harm the Youngest LungsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Exposed infants more susceptible to bronchiolitis, study finds Source: HealthDay Related MedlinePlus Topics: Bronchitis, Indoor Air Pollution, Infant and Toddler Health (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - November 6, 2009 Category: Consumer Health News Source Type: consumer

Air Pollution Increases Infants' Risk Of BronchiolitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Infants who are exposed to higher levels of air pollution are at increased risk for bronchiolitis, according to a new study. The study appears in the November 15 issue of the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. "There has been very little study of the consequences of early life exposure to air pollution," said Catherine Karr, M.D. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 6, 2009 Category: Consumer Health News Tags: Respiratory / Asthma Source Type: news

Air Pollution Increases Infants' Risk Of BronchiolitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Infants who are exposed to higher levels of air pollution are at increased risk for bronchiolitis, according to a new study. The study appears in the November 15 issue of the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. "There has been very little study of the consequences of early life exposure to air pollution," said Catherine Karr, M.D. (Source: Water Quality / Air Quality News From Medical News Today)
Source: Water Quality / Air Quality News From Medical News Today - November 6, 2009 Category: Nutrition Tags: Respiratory / Asthma Source Type: news

Air pollution and infants' bronchiolitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study is unique in that we were able to look at multiple sources including wood smoke in a region with relatively low concentrations of ambient air pollution overall"........ (Source: Medicineworld.org: New Article Alert)
Source: Medicineworld.org: New Article Alert - November 6, 2009 Category: Consumer Health News Source Type: info

Air pollution increases infants' risk of bronchiolitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(American Thoracic Society) Infants who are exposed to higher levels of air pollution are at increased risk for bronchiolitis, according to a new study. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 6, 2009 Category: Global & Universal Source Type: news

Impairment of T Cell Immunity by the Respiratory Syncytial Virus: Targeting Virulence Mechanisms for Therapy and Prophylaxis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Worldwide, Respiratory Syncytial Virus (RSV) causes severe bronchiolitis and pneumonia in children, the elderly and immuno-compromised individuals. Moreover, RSV is the mayor cause of infant hospitalization due to lower respiratory infection, regardless socioeconomic status. Accumulating data support the notion that immune responses elicited against naturally acquired RSV infections are non-lasting and inappropriate for efficient virus clearance. Although there is consensus over the capacity of RSV to impair the development of an effective and protective adaptive immune response, very little is known about specific vir...
Source: Current Medicinal Chemistry - November 5, 2009 Category: Chemistry Authors: González PA, Bueno SM, Riedel CA, Kalergis AM Tags: Curr Med Chem Source Type: journals

Antigen-Based Assays for the Identification of Influenza Virus and Respiratory Syncytial Virus: Why and How to Use Them in Pediatric PracticeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article describes the clinical and socioeconomic relevance of influenza (IV) and respiratory syncytial virus (RSV) in pediatrics, the characteristics and limitations of currently available assays, and the impact of rapid diagnostic tests. This article shows that rapid tests for the detection and identification of IV and RSV in the respiratory secretions of infants and children are useful in the diagnosis of common, and possibly severe diseases, such as influenza and bronchiolitis. The tests' specificity and sensitivity make them most reliable when the prevalence of influenza or RSV infection is high, which suggests th...
Source: Clinics in Laboratory Medicine - November 4, 2009 Category: Laboratory Medicine Authors: Nicola Principi, Susanna Esposito Source Type: journals

Respiratory Viruses in Bronchiolitis and Their Link to Recurrent Wheezing and AsthmaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Bronchiolitis is the leading cause of hospitalization for children younger than 1 year of age and these hospitalized children have an increased risk for developing childhood asthma. It remains unclear, however, which children who have severe bronchiolitis (eg, an episode requiring hospitalization) will develop recurrent wheezing or asthma. Although many environmental and genetic factors may play a role in the pathway from bronchiolitis to asthma, this article focuses on the viruses that have been linked to bronchiolitis and how these viruses may predict or contribute to future wheezing and asthma. The article also discusse...
Source: Clinics in Laboratory Medicine - November 4, 2009 Category: Laboratory Medicine Authors: Jonathan M. Mansbach, Carlos A. Camargo Source Type: journals

Use of hypertonic saline in treatment of bronchiolitis remains unclearEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hypertonic saline plus epinephrine offers no extra benefit over normal saline plus epinephrine in the treatment of infants with acute bronchiolitis, study findings show. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - November 4, 2009 Category: Respiratory Medicine Source Type: news

Use of hypertonic saline in treatment of bronchiolitis remains unclearEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hypertonic saline plus epinephrine offers no extra benefit over normal saline plus epinephrine in the treatment of infants with acute bronchiolitis, study findings show. (Source: MedWire News - Pediatrics)
Source: MedWire News - Pediatrics - November 4, 2009 Category: Pediatrics Source Type: news

ARTICLE: A Randomized Trial of Nebulized 3% Hypertonic Saline With Epinephrine in the Treatment of Acute Bronchiolitis in the Emergency DepartmentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions In the treatment of acute bronchiolitis, hypertonic saline and epinephrine did not improve clinical outcome any more than normal saline and epinephrine in the emergency setting. This differs from previously published results of outpatient and inpatient populations and merits further evaluation. Trial Registration isrctn.org Identifier: ISRCTN66632312 (Source: Archives of Pediatrics)
Source: Archives of Pediatrics - November 2, 2009 Category: Pediatrics Authors: Grewal, S., Ali, S., McConnell, D. W., Vandermeer, B., Klassen, T. P. Tags: Pediatrics, Pediatrics, Other, Pulmonary Diseases, Pulmonary Diseases, Other, Randomized Controlled Trial, Prognosis/ Outcomes, Archives Journal Club, Drug Therapy, Drug Therapy, Other, Emergency Medicine Article Source Type: journals

ADVICE FOR PATIENTS: Bronchiolitis and Respiratory Syncytial VirusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Archives of Pediatrics)
Source: Archives of Pediatrics - November 2, 2009 Category: Pediatrics Authors: Moreno, M. A., Furtner, F., Rivara, F. P. Tags: Viral Infections, Pediatrics, Neonatology and Infant Care, Pediatrics, Other, Pulmonary Diseases, Pulmonary Diseases, Other, Advice for Patients, Infectious Diseases Source Type: journals

A Randomized Trial of Nebulized 3% Hypertonic Saline With Epinephrine in the Treatment of Acute Bronchiolitis in the Emergency Department [Article]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions In the treatment of acute bronchiolitis, hypertonic saline and epinephrine did not improve clinical outcome any more than normal saline and epinephrine in the emergency setting. This differs from previously published results of outpatient and inpatient populations and merits further evaluation. Trial Registration isrctn.org Identifier: ISRCTN66632312 (Source: Archives of Pediatrics)
Source: Archives of Pediatrics - November 2, 2009 Category: Pediatrics Authors: Grewal, S., Ali, S., McConnell, D. W., Vandermeer, B., Klassen, T. P. Tags: Pediatrics, Pediatrics, Other, Pulmonary Diseases, Pulmonary Diseases, Other, Randomized Controlled Trial, Prognosis/ Outcomes, Archives Journal Club, Drug Therapy, Drug Therapy, Other, Emergency Medicine Article Source Type: journals

Bronchiolitis and Respiratory Syncytial Virus [Advice for Patients]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Archives of Pediatrics)
Source: Archives of Pediatrics - November 2, 2009 Category: Pediatrics Authors: Moreno, M. A., Furtner, F., Rivara, F. P. Tags: Viral Infections, Pediatrics, Neonatology and Infant Care, Pediatrics, Other, Pulmonary Diseases, Pulmonary Diseases, Other, Advice for Patients, Infectious Diseases Source Type: journals

Long-term outcome after bronchiolitis: No association with the invasiveness of the infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To the Editor: Carroll et al published in the Journal their interesting results from a retrospective population-based study on the association between the severity of bronchiolitis in infants less than 12 months old and asthma at 4.5 to 5.5 years of age. Among over 90,000 children, 18% had an infant bronchiolitis visit. The adjusted odds ratio for asthma was 1.86 for outpatients, 2.41 in the emergency ward, and 2.82 in the inpatient group, suggesting a dose-response relationship between the severity of bronchiolitis and later asthma. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - November 1, 2009 Category: Allergy & Immunology Authors: Eija Piippo-Savolainen, Marja Ruotsalainen, Matti Korppi Tags: Correspondence Source Type: journals

ReplyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To the Editor: In response to our recent article, Piippo-Savolainen et al share data from their well studied cohort of 83 subjects followed from early childhood for more than 25 years for asthma and other pulmonary outcomes. Several factors make it difficult to make comparisons to our recent findings from the work highlighted by Piippo-Savolainen et al, including the small sample size, the fact that their study was neither designed nor powered to address our study questions, differences between studies in how exposure and outcome variables were defined, and the lack of both a spectrum of bronchiolitis severity and a compa...
Source: Journal of Allergy and Clinical Immunology - November 1, 2009 Category: Allergy & Immunology Authors: Kecia N. Carroll, Tebeb Gebretsadik, Marie R. Griffin, Tina V. Hartert Tags: Correspondence Source Type: journals

Airway involvement in sarcoidosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sarcoidosis is a common disease and affects the respiratory system in > 90% of cases, most commonly the intrathoracic lymph nodes and the respiratory parenchyma. Less commonly, the airways are involved, and the disease is manifested as mucosal erythema, edema, granularity and cobblestoning, plaques, nodules, and bronchial stenosis, airway distortion, traction bronchiectasis, and bronchiolitis. Airway involvement may lead to airflow limitation. Involvement of oral, nasal, and pharyngeal mucosa may cause hoarseness, dysphagia, laryngeal paralysis, and upper airway obstruction. Airway symptoms are important indicators ...
Source: Chest - November 1, 2009 Category: Respiratory Medicine Authors: Polychronopoulos VS, Prakash UB Tags: Chest Source Type: journals

Oxidative Stress and Nutritional Intakes in Lung Patients With Bronchiolitis Obliterans SyndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, patients with severe BOS were more oxidatively stressed compared with mild and non-BOS recipients. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - November 1, 2009 Category: Transplant Surgery Authors: J. Madill, E. Aghdassi, B.M. Arendt, C. Gutierrez, L. Singer, C.-W. Chow, S. Keshavjee, J.P. Allard Tags: Thoracic Transplantation Source Type: journals

Gene therapy to aid lung transplantsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
“Donated lungs that have to be discarded because they are not good enough for transplant can now be repaired and made suitable for patients,” The Times has reported. The study behind the news looks at an experimental gene therapy technique that has been tested on pig and human lungs. Under this technique, a gene known as IL-10 is introduced into the lung tissue cells to alter their behaviour. The research showed that in experimental conditions the gene combatted the damaging inflammation that sometimes causes problems in lung transplants. The importance of the research is emphasised in a journal editorial, which poin...
Source: NHS News Feed - October 30, 2009 Category: Consumer Health News Tags: Heart/lungs Source Type: news

Fibrocytes are associated with vascular and parenchymal remodelling in patients with obliterative bronchiolitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Our results indicate that fibrocytes are associated with pathological remodelling processes in patients with obliterative bronchiolitis and that tissue fibrocytes might be a possible useful biomarker in these processes. (Source: Respiratory Research)
Source: Respiratory Research - October 30, 2009 Category: Respiratory Medicine Authors: Annika Andersson-SjolandJonas ErjefaltLeif BjermerLeif ErikssonGunilla Westergren-Thorsson Source Type: journals

Living-donor single lobe lung transplantation for bronchiolitis obliterans from mother to child following previous allogeneic hematopoietic stem cell transplantation from the same donor.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19866336 [PubMed - as supplied by publisher] (Source: International Journal of Hematology)
Source: International Journal of Hematology - October 29, 2009 Category: Hematology Authors: Oshima K, Kikuchi A, Mochizuki S, Yamane M, Date H, Hanada R Tags: Int J Hematol Source Type: journals

Lung Pathology in Fatal Novel Human Influenza A (H1N1) Infection.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Autopsies have shown that the main pathological changes associated with S-OIV infection are localized to the lungs, where three distinct histological patterns can be identified. We also show evidence of ongoing pulmonary aberrant immune response. Our results reinforce the utility of autopsy in increasing the understanding of the novel human influenza A (H1N1) infection. PMID: 19875682 [PubMed - as supplied by publisher] (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - October 29, 2009 Category: Intensive Care Authors: Mauad T, Hajjar LA, Callegari GD, da Silva LF, Schout D, Galas FR, Alves VA, Malheiros DM, Auler Jr JO, Ferreira AF, Borsato MR, Bezerra SM, Gutierrez PS, Caldini ET, Pasqualucci CA, Dolhnikoff M, Saldiva PH Tags: Am J Respir Crit Care Med Source Type: journals

Epinephrine and dexamethasone reduce hospital admission in children with bronchiolitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Thorax)
Source: Thorax - October 28, 2009 Category: Respiratory Medicine Authors: Fiandeiro, P T. Tags: Miscellanea Source Type: journals

Parents' charityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Son's near-death prompts campaign over bronchiolitis (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - October 26, 2009 Category: Consumer Health News Tags: Health Source Type: news

Successful establishment of primary small airway cell cultures in human lung transplantationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Primary SAEC can be successfully obtained from human lung transplant recipients and maintained in culture for downstream experimentation. This technique will facilitate the development of primary in vitro models for BOS and other diseases with a small airway component such as asthma, cystic fibrosis and COPD. (Source: Respiratory Research)
Source: Respiratory Research - October 26, 2009 Category: Respiratory Medicine Authors: Balarka BanerjeeAnthony KicicMichael MuskErika SutantoStephen StickDaniel Chambers Source Type: journals

Probable nitrofurantoin-induced bronchiolitis obliterans with organizing pneumonia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: An 89-year-old woman developed unresolving BOOP after three years of nitrofurantoin therapy. PMID: 19850785 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - October 25, 2009 Category: Drugs & Pharmacology Authors: Robinson C, Nyi PP Tags: Am J Health Syst Pharm Source Type: journals

Serum KL-6 levels as a biomarker of lung injury in respiratory syncytial virus bronchiolitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To evaluate whether KL-6 concentration is a useful biomarker of the severity of respiratory syncytial virus (RSV) bronchiolitis, we determined KL-6 concentrations in patients with RSV bronchiolitis with or without chronic heart disease (CHD). We enrolled 52 patients who had been diagnosed with RSV bronchiolitis and required admission to the hospital at the Department of Pediatrics of Fukushima Medical University School of Medicine from 2004 to 2005. These patients were divided into two groups: Group 1 consisted of patients without any underlying disease, and Group 2 consisted of patients with CHD. These patients were assig...
Source: Journal of Medical Virology - October 25, 2009 Category: Virology Authors: Yukihiko Kawasaki, Yoshimichi Aoyagi, Yusaku Abe, Hayato Go, Takashi Imamura, Mari Kaneko, Masaki Ito, Masahiko Katayose, Koichi Hashimoto, Mitsuaki Hosoya Tags: Research Article Source Type: journals

Bronchiolitis obliterans following hematopoietic stem cell transplantation: a clinical updateEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report provides a clinical update of the incidence, risk factors, pathogenesis, clinical characteristics, and management of bronchiolitis obliterans following HSCT. (Source: Clinical Transplantation)
Source: Clinical Transplantation - October 21, 2009 Category: Transplant Surgery Authors: Chirag M. Pandya, Ayman O. Soubani Source Type: journals

Combination of epinephrine and dexamethasone may reduce hospitalization in children with bronchiolitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Plint A, Johnson D, Patel H, Wiebe N, Correll R, Brant R, et al. Epinephrine and dexamethasone in children with bronchiolitis. N Engl J Med 2009;360:2079-89. Among infants with bronchiolitis, how effective is a combination of nebulized epinephrine and oral corticosteroids at preventing hospitalization? (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - October 20, 2009 Category: Pediatrics Authors: John G. Frohna, Urs Frey Tags: Current Best Evidence Source Type: journals

Heterogeneity in the clinical manifestations of mannose-binding lectin deficiencyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To the Editors: We read with interest the case report of an 11-month-old girl with mannose-binding lectin (MBL) deficiency presenting with recurrent infections. The infant had a history of bronchiolitis, pneumonia, periorbital cellulitis, and recurrent otitis media. She was found to have a serum MBL of (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - October 20, 2009 Category: Pediatrics Authors: Malcolm Brodlie, Terry Flood, David A. Spencer Tags: Letters to the Editor Source Type: journals

Apnea and RSV-associated bronchiolitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Although hypoxemia and length of hospital stay have been the focus of RSV-associated morbidity, apnea is a relatively common associated symptom that surprisingly has not been studied carefully, even though apnea has the potential to cause death. Authors of this systematic review point out that although apnea alone or risk of apnea may lead to some RSV hospitalizations because of concern for complications or even death, definition of apnea has not been standardized, apnea has not been studied prospectively, nor has the risk of death been established or prevention of occurrence by administration of monoclonal antibody evalua...
Source: The Journal of Pediatrics - October 20, 2009 Category: Pediatrics Authors: Sarah S. Long Tags: The Editors' Perspectives Source Type: journals

Cetuximab: Bronchiolitis obliterans organising pneumonia in an elderly patient: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - October 19, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Secondhand tobacco smoke exposure differentially alters nucleus tractus solitarius neurons at two different ages in developing non-human primates.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Exposing children to secondhand tobacco smoke (SHS) is associated with increased risk for asthma, bronchiolitis and SIDS. The role for changes in the developing CNS contributing to these problems has not been fully explored. We used rhesus macaques to test the hypothesis that SHS exposure during development triggers neuroplastic changes in the nucleus tractus solitarius (NTS), where lung sensory information related to changes in airway and lung function is first integrated. Pregnant monkeys were exposed to filtered air (FA) or SHS for 6-hrs/day, 5-days/week starting at 50-days gestational age. Mother/infant pairs conti...
Source: Toxicology and Applied Pharmacology - October 18, 2009 Category: Toxicology Authors: Sekizawa SI, Joad JP, Pinkerton KE, Bonham AC Tags: Toxicol Appl Pharmacol Source Type: journals

RSV Appears to Cause Heart Damage DirectlyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
SAN FRANCISCO — Respiratory syncytial virus itself, and not the bronchiolitis associated with the infection, appears to be the cause of the heart damage often seen in young children with the virus, according to a prospective study involving 74 children. (Source: Family Practice News)
Source: Family Practice News - October 15, 2009 Category: Primary Care Authors: Robert Finn Tags: Cardiovascular Medicine Source Type: news

Clinical prediction rule to diagnose post-infectious bronchiolitis obliterans in childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Infant pulmonary function testing has a great value in the diagnosis of post-infectious bronchiolitis obliterans (BOs), because of characteristic patterns of severe and fixed airway obstruction. Unfortunately, infant pulmonary function testing is not available in most pediatric pulmonary centers.To develop and validate a clinical prediction rule (BO-Score) to diagnose children under 2 years of age with BOs, using multiple objectively measured parameters readily available in most medical centers.Study subjects, children under 2 years old with a chronic pulmonary disease assisted at R. Gutierrez Children's Hospital of Buenos...
Source: Pediatric Pulmonology - October 13, 2009 Category: Respiratory Medicine Authors: Alejandro J. Colom, Alejandro M. Teper Source Type: journals

Non-RSV Bronchiolitis More Often Linked to Recurrent Wheezing Than RSV FormEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Children with bronchiolitis not induced by respiratory syncytial virus (RSV) are at increased risk for recurrent wheezing compared with their peers who have RSV-induced disease, according to a report in the September issue of Allergy. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 13, 2009 Category: Consumer Health News Tags: Allergy & Clinical Immunology Source Type: news

Incidence, molecular epidemiology and clinical presentations of human metapneumovirus; assessment of its importance as a diagnostic screening targetEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Numerically and through its association with respiratory disease, HMPV represents a diagnostically significant target that should be included in PCR-based routine screening of respiratory samples. Understanding the biological basis of observed rapid turnover of HMPV variants, including the observed HMPV genotype change between respiratory seasons requires further longitudinal studies. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - October 12, 2009 Category: Virology Authors: Eleanor Gaunt, E. Carol McWilliam-Leitch, Kate Templeton, Peter Simmonds Tags: Full length articles Source Type: journals

Comparison of the effects that two different respiratory physical therapy techniques have on cardiorespiratory parameters in infants with acute viral bronchiolitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: In terms of overall improvement of cardiorespiratory parameters, neither the EFIT nor vibration/PD provided any benefit to infants with BVA. However, over time, respiratory physical therapy seems to contribute to decreasing the RR in these patients. (Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - October 9, 2009 Category: Respiratory Medicine Source Type: journals

Viral pneumonia: epidemiological, clinical, pathophysiological and therapeutic aspectsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this review article was to show epidemiological, pathophysiological, clinical and therapeutic aspects of viral community-acquired pneumonia. These types of pneumonia are commonly caused by influenza A and B; parainfluenza 1, 2 and 3; respiratory syncytial virus; or adenovirus. We also address the types of pneumonia caused by hantaviruses, metapneumoviruses and rhinoviruses. (Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - October 9, 2009 Category: Respiratory Medicine Source Type: journals