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Fight Aging! Newsletter, September 3rd 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - September 2, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Magnetic Nanoparticles Pull Cancer Biomarkers from Whole Blood
MicroRNA molecules are short RNA strings that bind to certain messenger RNAs, in the process blocking messenger RNAs from being translated to create new proteins. When microRNAs aren’t operating properly, cancer may be the cause, but this conne...
Source: Medgadget - August 30, 2018 Category: Medical Devices Authors: Editors Tags: Genetics Nanomedicine Source Type: blogs

Is EPA Changing the Regulatory Paradigm?
Sometimes it ’s worth reading the fine print in obscure regulatory proposals. One such example is contained in a “proposed rulemaking” by the EPA on what are called “dose-response models.”Buried in theFederal Register a few months back (on April 30) is this seemingly innocuous verbiage:EPA should also incorporate the concept of model uncertainty when needed as a default to optimize dose risk estimation based on major competing models, including linear, threshold, U-shaped, J-shaped and bell-shaped models.Your eyes glaze over, right?Instead they should be popping out. EPA is proposing a major change in the way we ...
Source: Cato-at-liberty - August 27, 2018 Category: American Health Authors: Patrick J. Michaels Source Type: blogs

Raj of the NHS – How doctors from India and Pakistan saved the NHS
By ROHIN FRANCIS  India and Pakistan celebrate 71 years of Independence today. The British National Health Service owes them a debt of gratitude. Great Britain’s national dish is famously chicken curry, but South Asia’s impact on this sceptred isle extends far beyond food. It is a testament to how ingrained into the British psyche the stereotypical Indian doctor has become that in 2005 a poll of Brits found the doctor they’d most like to consult is a 30-something South Asian female. In 2010 the BBC even ran a popular TV series simply entitled ‘The Indian Doctor’ following a story played out across the UK in the...
Source: The Health Care Blog - August 15, 2018 Category: Consumer Health News Authors: at RogueRad Tags: NHS Source Type: blogs

What ' s in a name?
From time to time I have commented on the controversies over cancer screening. Most people assume that screening is an unqualified good, that early detection of cancer saves lives. Whenever some panel proposes recommending less screening, we hear screaming and yelling from advocates who claim they are trying to " ration " health care to save money at the expense of people ' s lives.In fact,as a bunch of Australians and a Minnesotan explain in BMJ, there are a few conditions called " cancer " that you are better off not treating, or perhaps treating very conservatively. These include what is called ductal carcinoma in situ ...
Source: Stayin' Alive - August 13, 2018 Category: American Health Source Type: blogs

As I ’ve always suspected, Health Care = Communism + Frappuccinos
By MATTHEW HOLT Happy 15th birthday THCB! Yes, 15 years ago today this little blog opened for business and changed my life (and at least impacted a few others). Later this week we are going to celebrate and tell you a bit more about what the next 15 years (really?) of THCB might look like. But for now, I’m rerunning a few of my favorite pieces from the mid-2000s, the golden age of blogging. Today I present “Health Care = Communism + Frappuccinos”, one of my favorites about the relationship between government and private sector originally published here on Jan7, 2005. And like the Medicare one from last we...
Source: The Health Care Blog - August 12, 2018 Category: Consumer Health News Authors: matthew holt Tags: Matthew Holt OP-ED 15th Birthday Celebration Commumism Frappuchinos Source Type: blogs

A blood test to detect melanoma? Not so fast.
The headline scrolling across the bottom of an evening news show certainly grabbed my attention: a new blood test had the possibility of detecting early melanoma and saving thousands of lives. And then there were more reports elevating this early research report to a point that I became quite interested — and frankly concerned. News flash: The research is far from being shown to have proven value in the early diagnosis of melanoma, a less common but certainly potentially deadly form of skin cancer. I am not certain the various media headlines and articles appropriately reflected that fact, once again offering hyp...
Source: Kevin, M.D. - Medical Weblog - July 31, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/j-leonard-lichtenfeld" rel="tag" > J. Leonard Lichtenfeld, MD < /a > Tags: Conditions Dermatology Oncology/Hematology Source Type: blogs

Methadone and Mixed Messages
As a physician licensed to prescribe narcotics, I am legally   permitted to prescribe the powerful opioid methadone (also known by the brand name Dolophine  ) to my patients suffering from severe, intractable pain that hasn ’t been adequately controlled by other, less powerful pain killers. Most patients I encounter who might fall into that category are likely to be terminal cancer patients. I’ve often wondered why I am approved to prescribe methadone to my patients as a treatment for pain, but I am not allowed to prescribe methadone to taper my patients off of a physical dependence they may have developed from lo...
Source: Cato-at-liberty - July 13, 2018 Category: American Health Authors: Jeffrey A. Singer Source Type: blogs

Just To Point Out It Is Seven Months Since We Heard From The ADHA Board
Captured today at 1:30pm. Australian Digital Health Agency BoardDownload the latest Board Meeting - 6 December 2017 - Board Papers Mr Jim Birch AM, Chair is also Chair of the Australian Red Cross Blood Service, Deputy Chair of the Independent Hospital Pricing Authority, Chair of Mary MacKillop Care SA and a board member of the Australian Red Cross Society, the Little Company of Mary Health Care and Cancer SA. He was formally a Partner in Ernst and Young having been the Global Health Leader. He has also been the Government and Public Sector Leader from 2012 until the end of 2014. Formerly Mr Birch was also the Lead Part...
Source: Australian Health Information Technology - July 7, 2018 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Fight Aging! Newsletter, June 25th 2018
In this study, we investigate mitochondrial energetics and mtDNA methylation in senescent cells, and evaluate the potential of humanin and MOTS-c as novel senolytics or SASP modulators that can alleviate symptoms of frailty and extend health span by targeting mitochondrial bioenergetics. Exercise versus the Hallmarks of Aging https://www.fightaging.org/archives/2018/06/exercise-versus-the-hallmarks-of-aging/ The paper I'll point out today walks through the ways in which exercise is known to beneficially affect the Hallmarks of Aging. The Hallmarks are a list of the significant causes of aging that I dis...
Source: Fight Aging! - June 24, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Failure of the Imagination when it comes to Human Longevity
Researchers recently published a study on attitudes to longevity that is reminiscent of the 2013 Pew survey. When asked, people want to live a little longer than their neighbors, at the high end of the normal life span for old individuals today. When asked how long they want to live given the guarantee of perfect health, people pick a number close to the maximum recorded human life span. This sounds like a collusion between the instinctive desires for first conformity and secondly hierarchy, deeply entwined with the human condition, present in all of our primate cousins, a self-sabotaging gift from our evolutionary heritag...
Source: Fight Aging! - June 21, 2018 Category: Research Authors: Reason Tags: Activism, Advocacy and Education Source Type: blogs

Tropical Travel Trouble 008 Total TB Extravaganza
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 008 Peer Reviewer Dr McBride ID physician, Wisconsin TB affects 1/3rd of the population and one patient dies every 20 seconds from TB. Without treatment 50% of pulmonary TB patients will be dead in 5 years. In low to middle income countries both TB and HIV can be ubiquitous, poor compliance can lead to drug resistance and malnourished infants are highly susceptible. TB can be very complex and this post will hopefully give you the backbone to TB m...
Source: Life in the Fast Lane - June 16, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Clinical Cases Tropical Medicine Genexpert meningitis TB TB meningitis Tuberculosis Source Type: blogs

Funtabulously Frivolous Friday Five 241
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 241. Readers can subscribe to FFFF RSS or subscribe to the FFFF weekly EMAIL Question 1 Which family shares 4 Nobel prizes? A Nobel prize between wife and husband, followed by a second prize for the wife and a later prize to their daughter. Reveal Answer expand(docu...
Source: Life in the Fast Lane - June 14, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five battle of troy burkholderia mallei cannabis cirrhosis CPR greek soldiers irene joliot-curie kiss of life marie curie moroccan fishermen nobel prize peter safar pierre curie pseudomonas mallei Rene Laenne Source Type: blogs

Exercise as part of cancer treatment
In a first, a national cancer organization has issued formal guidelines recommending exercise as part of cancer treatment, for all cancer patients. The Clinical Oncology Society of Australia (COSA) is very clear on the directive. Its recommendations are: Exercise should be embedded as part of standard practice in cancer care and viewed as an adjunct therapy that helps counteract the adverse effects of cancer and its treatment. All members of the multi-disciplinary cancer team should promote physical activity and help their patients adhere to exercise guidelines. Best practice cancer care should include referral to an accr...
Source: Harvard Health Blog - June 13, 2018 Category: Consumer Health News Authors: Monique Tello, MD, MPH Tags: Cancer Exercise and Fitness Health Source Type: blogs

The Unknown Part of Anthony Bourdain
“Last time I saw all this, I think it’s fair to say, I was at a turning point in my life,” Anthony Bourdain says before embarking into the Borneo jungle. He was not afraid to discuss his long battle with substance use, an issue that millions of Americans struggle with. In fact, recent data shows that annual deaths from opioid misuse have surpassed deaths by car accidents, guns, or breast cancer, highlighting an astoundingly dramatic increase in nationwide substance use disorders. 1, 2 “I have been hardened by the last 10 years. I don’t know what that says about me… but, there it is.” A crooked and nostalg...
Source: World of Psychology - June 9, 2018 Category: Psychiatry & Psychology Authors: Amanda Marie Cardinale Tags: Celebrities Depression General Stigma Suicide anthony bourdain bourdain suicide suicide of anthony bourdain Source Type: blogs