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Fight Aging! Newsletter, September 17th 2018
In this study, we found that TXNIP deficiency induces accelerated senescent phenotypes of mouse embryonic fibroblast (MEF) cells under high glucose condition and that the induction of cellular ROS or AKT activation is critical for cellular senescence. Our results also revealed that TXNIP inhibits AKT activity by a direct interaction, which is upregulated by high glucose and H2O2 treatment. In addition, TXNIP knockout mice exhibited an increase in glucose uptake and aging-associated phenotypes including a decrease in energy metabolism and induction of cellular senescence and aging-associated gene expression. We propose that...
Source: Fight Aging! - September 16, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Addiction Abuse
Hardly a day goes by without a report in the press about some new addiction. There are warnings about addiction to  coffee. Popular psychology publications talk of “extreme sports addiction. ” Some news reports even alert us to the perils of chocolate addiction. One gets the impression that life is awash in threats of addiction. People tend to equate the word “addiction” with “abuse.” Ironically, “addiction” is a subject of abuse.The American Society of Addiction Medicine  defines addiction as a “chronic disease of brain reward, motivation, memory and related circuitry…characterized by the inabilit...
Source: Cato-at-liberty - September 13, 2018 Category: American Health Authors: Jeffrey A. Singer Source Type: blogs

For Senolytics Companies, an Effective Piperlongumine would be a Greater Competitive Threat than Dasatinib
Senolytic treatments selectively destroy senescent cells, and several different approaches have been shown to produce some degree of rejuvenation in mice: reversal of measures of aging; reversal of the progression of specific age-related conditions; extension of life span. Most of these initial senolytics are repurposed pharmaceuticals drawn from cancer research databases, with the exceptions being the engineered peptide FOXO4-DRI, the suicide gene therapy developed by Oisin Biotechnologies, and SIWA Therapeutics' immunotherapy. Where animal study data has been published, the results produced by these varied senolytics are...
Source: Fight Aging! - September 11, 2018 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs

‘No-deal’ Brexit
What the Government ’s plans could mean for cancer treatment, care and research Related items fromOnMedica Hunt praises GPs for ‘extraordinary dedication’ Doctors bear burden of Government ’s financial failure Health Foundation sets out reasons for more NHS investment Questions on Health Economics and commissioning Microbes don ’t need visas! The reality of Brexit and public health
Source: OnMedica Blogs - September 11, 2018 Category: General Medicine Source Type: blogs

Patient Verification and The State of Blockchain Adoption with Shyft Network CEO Bruce Silcoff
From prior authorization to cannabinoid oil, Medgadget has recently covered a range of companies leveraging blockchain technology to impact one or more aspects of healthcare. For this piece, similar to our conversation with technology thought leader...
Source: Medgadget - September 10, 2018 Category: Medical Devices Authors: Michael Batista Tags: Exclusive Informatics Medicine Public Health Source Type: blogs

The Rocky Road from the Military to the VA
While serving in the military, few think about what comes next. What happens if you are injured and the physical, mental, emotional damage does not go away? Who is tasked to make you “whole” again through health care and compensation? It is a process with which most civilians, and many service members and their families have little familiarity. It is cumbersome, and starts when the individual is still in the service, with a transition program and virtually no follow up by the military. For the last twenty years, the Department of Labor (DOL) Veterans Employment and Training Services (VETS) has provided grants to the Na...
Source: Disruptive Women in Health Care - September 10, 2018 Category: Consumer Health News Authors: dw at disruptivewomen.net Tags: Uncategorized Source Type: blogs

The Price of Progress or the Waste of Regulation?
The average cost of delivering a new therapy from laboratory to clinic is increasing at a fast pace, more than doubling since the turn of the century according to some studies, to stand at $2.5 billion or more. This is not driven by the work of research and development becoming more expensive: if anything, the price of the tools of biotechnology is in free fall, even as capacity increases by orders of magnitude. Biotechnology has gone through, and is still going through, its own echoed version of the computing revolution of recent decades. A mix of advances in computational power and materials science means that a graduate...
Source: Fight Aging! - September 7, 2018 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs

Deton is Developing “Aerosol Biopsy” to Detect Lung Diseases
Biopsies and bronchoscopies are the gold standard for diagnosing lung diseases, including pneumonia and cancer. However, these procedures are difficult to provide, requiring general anesthesia and an operating room. Deton hopes to simplify the proces...
Source: Medgadget - September 7, 2018 Category: Medical Devices Authors: Cici Zhou Tags: Diagnostics Exclusive Medicine Oncology Pathology Thoracic Surgery Source Type: blogs

Fight Aging! Newsletter, September 3rd 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - September 2, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Rauner Veto Preserves Consumer Protections in Short-Term Plans, Improves ObamaCare ' s Risk Pools
Hours ago, Illinois Gov. Bruce Rauner (R)vetoedlegislation that would have subjected enrollees in short-term health insurance  plans to higher deductibles, higher administrative costs, higher premiums, and lost coverage. The vetoed bill would have blocked the consumer protections made available in that market bya final rule issued earlier this month by the U.S. Department of Health and Human Services, and would have (further) jeopardized ObamaCare ’s risk pools by forcing even more sick patients into those pools.Short-term plans are exempt from federal health insurance regulations, and as a result offerbroader access to...
Source: Cato-at-liberty - August 27, 2018 Category: American Health Authors: Michael F. Cannon Source Type: blogs

Cannabidiol (CBD) — what we know and what we don’t
Cannabidiol (CBD) has been recently covered in the media, and you may have even seen it as an add-in booster to your post-workout smoothie or morning coffee. What exactly is CBD? Why is it suddenly so popular? How is cannabidiol different from marijuana? CBD stands for cannabidiol. It is the second most prevalent of the active ingredients of cannabis (marijuana). While CBD is an essential component of medical marijuana, it also is derived directly from the hemp plant, which is a cousin of the marijuana plant. While CDB is a component of marijuana (one of hundreds), CBD by itself, does not cause a “high.” According to a...
Source: Harvard Health Blog - August 24, 2018 Category: Consumer Health News Authors: Peter Grinspoon, MD Tags: Drugs and Supplements Health Marijuana Source Type: blogs

31 Successful Wellness Businesses to Inspire Your Inner Entrepreneur
This article is a resource for those who are thinking about starting a wellness business, and for those looking to develop their existing ones. This list of successful wellness businesses includes a description of what makes each wellness business unique, and the business models they're using. It explores 5 different types of businesses in the wellness industry: apps, content hubs, retail, coaching, and non-profits/organizations, which are all options you may consider. This article will give you inspiration for finding your idea, refining your idea, and creating a business model that works. Apps: Headspace: What makes ...
Source: PickTheBrain | Motivation and Self Improvement - August 16, 2018 Category: Consumer Health News Authors: mattrosenblum Tags: career featured money and finance productivity tips self improvement working from home business ideas entrepreneurship motivation success wellness Source Type: blogs

Cats & Dogs: Can We Find Unity on Health Care IT Change?
By MATTHEW HOLT Today we have a humming economy and insane politics. In early 2009 we were in economic meltdown and were about one week into the sanest, soberist Administration and even Congress over many recent decades. In February 2009 They passed a stimulus bill that had a huge impact on the health IT market (and still does). At that time there was much debate on THCB about what the future of health IT policy should look like and how the stimulus “Meaningful Use” money should be spent. My January 2009 summary of that whole debate introduced the notion of “Cats and Dogs in health IT”. They’...
Source: The Health Care Blog - August 15, 2018 Category: Consumer Health News Authors: matthew holt Tags: Matthew Holt 2008 Election EHR Health 2.0 Policy Policy/Politics RHIOs Startups Source Type: blogs

Raj of the NHS – How doctors from India and Pakistan saved the NHS
By ROHIN FRANCIS  India and Pakistan celebrate 71 years of Independence today. The British National Health Service owes them a debt of gratitude. Great Britain’s national dish is famously chicken curry, but South Asia’s impact on this sceptred isle extends far beyond food. It is a testament to how ingrained into the British psyche the stereotypical Indian doctor has become that in 2005 a poll of Brits found the doctor they’d most like to consult is a 30-something South Asian female. In 2010 the BBC even ran a popular TV series simply entitled ‘The Indian Doctor’ following a story played out across the UK in the...
Source: The Health Care Blog - August 15, 2018 Category: Consumer Health News Authors: at RogueRad Tags: NHS Source Type: blogs

The Top Bioprinting Companies
In the next 5-7 years, the bioprinting market is estimated to expand by 15.7 percent, and it is anticipated to grow over $4.70 billion by 2025, according to the latest study of BIS Research. While the growth statistics indicate a turbulent landscape, it is worth familiarizing with the main players. Here, we collected the best bioprinting companies currently on the market. The future of bioprinting: tissues not organs The idea of lab-grown organs might mean the end of testing drugs on animals or humans, the solution for organ shortages and an ending of the desperate state of organ donations worldwide. If the creators of the...
Source: The Medical Futurist - August 14, 2018 Category: Information Technology Authors: nora Tags: 3D Printing in Medicine Biotechnology Business Future of Medicine 3d printed bioprinting company Healthcare Innovation market regenerative skin Source Type: blogs