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Fight Aging! Newsletter, December 27th 2021
We report that whereas microglia are characterized by marked gene-level alterations related to negative regulation of protein phosphorylation and phagocytic vesicles, astrocytes show activation of enzyme- or peptidase-inhibitor signaling after detectable changes in BBB permeability. We also identify several genes enriched in these pathways that are notably altered after BBB breakdown. Our data reveal that microglia and astrocytes play an active role in maintaining BBB stabilization and corralling infiltrating cells, and thus might potentially function in ameliorating the lesions and neurologic disabilities in CNS diseases....
Source: Fight Aging! - December 26, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, November 8th 2021
In conclusion, in less common and visible cardiovascular diseases, it is crucial to recognize substantial progress and achievement, given that penetration of such information into clinical practice and the patient community can be inconsistent. Diseases such as hypertrophic cardiomyopathy, pulmonary arterial hypertension, and ATTR cardiac amyloidosis, once linked to a uniformly adverse prognosis, are now associated with the opportunity for patients to experience satisfactory quality of life and extended longevity.
VitaDAO, a Novel Approach to Crowdfunding Life Science Research
https://www.fightaging.org/archive...
Source: Fight Aging! - November 7, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Atherosclerosis, the As Yet Undefeated Monster
As you may know, I co-founded Repair Biotechnologies, a company presently focused on developing an approach to rapidly reverse the cholesterol content of atherosclerotic lesions, a goal that is impossible to achieve using the existing panoply of treatments for atherosclerosis. We use gene therapy techniques to provide cells with the ability to safely break down excess cholesterol, enabling the removal of pathological levels of intracellular cholesterol and localized deposits of extracellular cholesterol that characterize conditions such as atherosclerosis (in blood vessel walls) and NASH (in the liver). Atherosclerosis is ...
Source: Fight Aging! - November 2, 2021 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
Artificial Intelligence Will Redesign Healthcare
Artificial intelligence in healthcare has an unimaginable potential. Within the next couple of years, it will revolutionize every area of our life, including medicine. I am fully convinced that it will redesign healthcare completely – and for the better. Let’s take a look at the promising solutions it offers.
I am certain that healthcare will be the lead industrial area of such a revolution and one of the major catalysts for change is going to be artificial intelligence. Check the updated version of A Guide To Artificial Intelligence In Healthcare to understanding, anticipating and controlling artificial intell...
Source: The Medical Futurist - September 2, 2021 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Future of Medicine AI Healthcare Hospital ibm watson Innovation GC1 big data google deepmind Source Type: blogs
Artificial Intelligence In Healthcare: 10 Medical Fields A.I. Will Change Completely
Artificial intelligence in healthcare has an unimaginable potential. Within the next couple of years, it will revolutionize every area of our life, including medicine. I am fully convinced that it will redesign healthcare completely – and for the better. Let’s take a look at the promising solutions it offers.
I am certain that healthcare will be the lead industrial area of such a revolution and one of the major catalysts for change is going to be artificial intelligence. Check the updated version of A Guide To Artificial Intelligence In Healthcare to understanding, anticipating and controlling artificial in...
Source: The Medical Futurist - September 2, 2021 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Future of Medicine AI Healthcare Hospital ibm watson Innovation GC1 big data google deepmind Source Type: blogs
Anti ‐Vaxxers Turn to Big Government
Thomas A. FireyCOVID-19hospitalizations anddeaths are rising in the United States as the highly infectious Delta variant of the SARS-CoV-2 virus has becomethe dominant strain in the country. These serious cases arealmost entirely limited to people who are not vaccinated against the virus; for the vaccinated,infection rates are much lower and nearly all infections are no more troublesome than a cold or — at worst – a bout of the flu, and often go unnoticed altogether.COVID-19 causedat least11 percent of all U.S. deaths in 2020, making it thethird leading cause of death, behind only heart disease and cancer. So far in 20...
Source: Cato-at-liberty - August 2, 2021 Category: American Health Authors: Thomas A. Firey Source Type: blogs
Fight Aging! Newsletter, August 2nd 2021
This study aimed to determine the association between: (i) cognitive decline and bone loss; and (ii) clinically significant cognitive decline on Mini Mental State Examination (MMSE) over the first 5 years and subsequent fracture risk over the following 10 years. A total of 1741 women and 620 men aged ≥65 years from the population-based Canadian Multicentre Osteoporosis Study were followed from 1997 to 2013. Over 95% of participants had normal cognition at baseline. After multivariable adjustment, cognitive decline was associated with bone loss in women but not men. Approximately 13% of participants experienced sign...
Source: Fight Aging! - August 1, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
More Than 25 Years of Competition and Collaboration Advance the Prediction of Protein Shapes
Proteins (such as hemoglobin, actin, and amylase) are workhorse molecules that contribute to virtually every activity in the body. Some of proteins’ many jobs include carrying oxygen from your lungs to the rest of your body (hemoglobin), allowing your muscles to move (actin and myosin), and digesting your food (amylase, pepsin, and lactase). All proteins are made up of chains of amino acids that fold into specific 3D structures, and each protein’s structure allows it to perform its distinct job. Proteins that are misfolded or misshapen can cause diseases such as Parkinson’s or cataracts.
While it’s straightforwa...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - July 14, 2021 Category: Research Authors: Chrissa Chverchko Tags: Molecular Structures Cool Tools/Techniques Modeling Proteins Scientific Process Source Type: blogs
3D Printing in Medicine And Healthcare – The Ultimate List In 2021
3D printing has demonstrated huge potential for the future of medicine in the previous years, and its development is unstoppable. Just look at the impressive list of 3D printed healthcare materials and medical equipment below!
How does 3D printing in medicine work?
3D printing in medicine is part of the innovative process called additive manufacturing, which means producing three-dimensional solid objects from a digital file. How the technology works, we explained the technology in our article on bioprinting here.
As technology evolves, researchers work on various solutions. For example, engineers from the University of B...
Source: The Medical Futurist - July 13, 2021 Category: Information Technology Authors: berci.mesko Tags: 3D Printing Biotechnology Future of Medicine Healthcare Design Medical Education Personalized Medicine bioprinting Innovation Video GC1 3d printed biomaterial tissue engineering Source Type: blogs
We need to do better: Caring for patients after cancer treatment
The number of cancer survivors currently in the U.S. is around 15 million. With the rapid advancement of improved treatments and early detection, this number is expected to increase to over 20 million by 2026. I am lucky enough to be one of the survivors, now fourteen years out from my diagnosis of cervical cancer.Read more …Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more.
Source: Kevin, M.D. - Medical Weblog - July 11, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/sheila-crow" rel="tag" > Sheila Crow, PhD < /a > < /span > Tags: Conditions Oncology/Hematology Source Type: blogs
Let the mourning wear black
What a year of change. A pandemic. Cancer. Death. Loss. Fighting. Abandonment. Pain. Becoming an orphan. Becoming a caregiver. My family was hit with a sledgehammer and crushed into pieces. My joyful plans and decades of hard work wiped away with the insidious evil of a 5 x 7 mm tumor that spread like theRead more …Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more.
Source: Kevin, M.D. - Medical Weblog - July 8, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/anonymous" rel="tag" > Anonymous < /a > < /span > Tags: Physician COVID-19 coronavirus Infectious Disease Source Type: blogs
Human connections, cancer care, and COVID-19 restrictions
The desire for human connection is so irrevocably and putatively a tenet of the human condition. The relationships we form with one another are quintessential in adding value to our lives and in fostering loving bonds. And the way we express this connection with one another could be through a multitude of means, whether itRead more …Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more.
Source: Kevin, M.D. - Medical Weblog - June 20, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/nghia-pham" rel="tag" > Nghia Pham, MD < /a > < /span > Tags: Physician COVID-19 coronavirus Hospital-Based Medicine Infectious Disease Oncology/Hematology Source Type: blogs
Today is the day you ’ll have to die
She was listless in bed with agonal breathing — only 63 years old. Before stage 4 colon cancer claimed my mother, she chose to come home to her house … her bedroom, where she’d stare out her window at the dogwood trees that symbolized the blood of Jesus. A once-vibrant Italian Catholic and mother ofRead more …Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more.
Source: Kevin, M.D. - Medical Weblog - June 13, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/debbie-moore-black" rel="tag" > Debbie Moore-Black, RN < /a > < /span > Tags: Conditions Palliative Care Source Type: blogs
The Data Revolution: Personalized Medicine and the Future of Healthcare
The following is a guest article by Dr. Waqaas Al-Siddiq, Chairman, CEO & Founder at Biotricity. In 2011, near the end of his almost decade-long fight with cancer, Steve Jobs had a realization: “I think the biggest innovations of the 21st century will be at the intersection of biology and technology. A new era is beginning.” […]
Source: EMR and HIPAA - June 7, 2021 Category: Information Technology Authors: Guest Author Tags: Clinical Genomics-Precision Medicine Health IT Company Healthcare IT Biotricity CliniCloud Digital Health Digital Therapeutics Epigenetics Healthy.io Medical Sensors MIR Smart Personalized Medicine Waqaas Al-Siddiq Source Type: blogs
Why people diagnosed with cancer should get a second opinion
Although people think of medicine as a science —the facts reveal the diagnosis, the diagnosis dictates the treatment—most physicians acknowledge that medicine is as much an art as a science. It’s not like a simple math equation with one undeniably right answer. Even when the diagnosis is clear, there may still be multiple appropriate treat ment pathsRead more …Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more.
Source: Kevin, M.D. - Medical Weblog - June 6, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/miles-j-varn" rel="tag" > Miles J. Varn, MD < /a > < /span > Tags: Physician Oncology/Hematology Source Type: blogs
