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Evidence based medicine and politics
I ' m not sure if you can read this -- I have a cookie that gives me access, but the URL doesn ' t include the proxy server and it appears to be accessible. Let me know. Anyway, it ' sa discussion in NEJM of the U.S. Preventive Services Task Force. The USPSTF is a panel of clinical experts convened by the Agency for Healthcare Research and Quality, AHRQ, which is usually pronounced like ark. It draws on available research to evaluate screening tests and preventive interventions. An A or B grade means they recommend it. A C grade means it might be worthwhile for some people, but you should discuss it with your doctor and ma...
Source: Stayin' Alive - January 5, 2023 Category: American Health Source Type: blogs

Modified mRNA Demonstrates 10-Fold Protein Production
Scientists at Hong Kong University of Science and Technology came up with a technique to increase the efficiency and potentially the efficacy of mRNA therapeutics. mRNA molecules have what is called a poly-A tail, which is basically a string of adeni...
Source: Medgadget - December 2, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Genetics Medicine HKUniversity Source Type: blogs

The Top 10 Digital Health Stories Of 2022
Edging towards the end of the year, it is time for a summary of how digital health progressed in 2022. It is easy to get lost in the noise – I myself shared well over a thousand articles, studies and news items between January and the end of November 2022. Thus, just like in 2021, 2020 (and so on), I picked the 10 topics I believe will have the most significance in the future of healthcare. 1. The Rise Of Digital Therapeutics (DTx) Unlike a number of unsubstantial hypes (NFTs, Metaverse to name a few), we see DTx as a meaningful trend that has the capacity to bring major short-term improvements in personalised ...
Source: The Medical Futurist - November 29, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF digital health pharma drones digital health trends vocal biomarkers WHO DTx digital therapeutics Metaverse virtual ward summary AI healthcare worker Source Type: blogs

Fight Aging! Newsletter, November 28th 2022
This study explored whether determining the gain or loss of specific taxa represent a more precise metric of healthy/unhealthy aging than summary microbiome statistics, such as diversity and uniqueness. We analyzed microbiome diversity and four measures of microbiome uniqueness in 21,000 gut microbiomes for their relationship with aging and health. We show that diversity and uniqueness measures are not synonymous; uniqueness is not a uniformly desirable feature of the aging microbiome, nor is it an accurate biomarker of healthy aging. Different measures of uniqueness show different associations with diversity and with mark...
Source: Fight Aging! - November 27, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, November 14th 2022
In this study, we show that TXNIP is vital for the cell fate choice when cells are challenged by various stress signals. Furthermore, prolonged IGF1 treatment leads to the establishment of a premature senescence phenotype characterized by a unique senescence network signature. Combined IGF1/TXNIP-induced premature senescence can be associated with a typical secretory inflammatory phenotype that is mediated by STAT3/IL-1A signaling. Finally, these mechanistic insights might help with the understanding of basic aspects of IGF1-related pathologies in the clinical setting. Investigating the Ability of Type 2 Diabetes...
Source: Fight Aging! - November 13, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Does Surviving The Plague Mean You Will Eventually Contract An Autoimmune Disease?
BY MIKE MAGEE This Fall, I am teaching a 4-week course on “How Epidemics Have Shaped Our World” at the President’s College at the University of Hartford. It is, of course a timely topic, but also personally unnerving as we complete a third year under the shadow of Covid-19. Where does one begin on a topic such as this? Yale historian, Frank M. Snowden, in his book “Epidemics and Society: From the Black Death to the Present”, made his intentions obvious. He would begin with the plaque. Why? His answer, “The word ‘plague’ will always be synonymous with ‘terror’”, and especially references: ...
Source: The Health Care Blog - October 26, 2022 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy Public Health Autoimmune. Disease Mike Magee Plague Source Type: blogs

Dr Margaret Vaux Has Exposed A Problem With Health Department / Medicare Technology!
Last Monday the ABC and The Nine News Outlets made a big splash with the following headlines:‘Medicare is haemorrhaging’: The rorts and waste costing taxpayers billions of dollars a yearByAdele Ferguson and Chris GillettOctober 17, 2022 — 5.00amBillions of dollars are being rorted from Medicare each year by medical practitioners making mistakes or charging for services that aren ’t necessary or didn’t even happen – including billing dead people and falsifying patient records to boost profits.The revelations come as GPs lobby the federal Labor government to boost Medicare funding and increase rebates, claiming t...
Source: Australian Health Information Technology - October 23, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Clinical Research
This subject is quite complicated and it will be difficult for me to address it coherently in the space of a blog post. Lay people, unfortunately, are prone to many misunderstandings of clinical research and lately political opportunists have taken to exploiting these misunderstandings. Joseph Ladapo, the Florida Surgeon General, is one of these. He either doesn ' t know what he ' s doing when it comes to epidemiological research, or he ' s just a liar. Probably a little bit of both.The entire community of relevant experts rejects his conclusion that young men should not get the Covid vaccine, not because they don ' t like...
Source: Stayin' Alive - October 14, 2022 Category: American Health Source Type: blogs

Weekly Overseas Health IT Links – 8th October, 2022.
This report aligns with the reality that healthcare organizations are facing in terms of the effects to patient safety, " said Anahi Santiago, chief information security officer at Delaware-based ChristianaCare.She and other healthcare cybersecurity leaders spoke withHealthcare IT News about the connection between cyber hygiene and patient safety and how to prepare for healthcare cyber attacks. -----https://ehrintelligence.com/news/meaningful-use-ehrs-may-be-key-to-improved-quality-of-care‘Meaningful Use’ EHRs May Be Key to Improved Quality of CareHospitals that meet the “Meaningful Use” EHR requirements were ...
Source: Australian Health Information Technology - October 8, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

TLC Todd-versations: Todd Linsky in Conversation with Dr. Alan Greene
Todd Linsky, a food and organic industry veteran, hosts the podcast Todd-versations. He interviews guests from around the globe — influencers, leaders, and innovators in their respective fields. In this episode, Todd and Dr. Greene discuss the pediatric roots of longevity, the importance of nutrition in health, Dr. Greene’s reasons for creating DrGreene.com, his next projects, and a whole host of side topics. Transcript of Todd-versation Podcast with Todd Linsky and Dr. Greene 0:00 this conversation is brought to you in part by Calavo Growers the family of fresh! 0:19 hey there everybody good ...
Source: Conversations with Dr Greene - October 6, 2022 Category: Child Development Authors: Alan Greene MD Tags: Dr. Greene's Blog Source Type: blogs

Weekly Overseas Health IT Links –1st October, 2022.
This article details information required for integration into EHRs to build personalized treatment plans and develop successful SDOH programs that provide resources and support for patients in need. In addition, successful SDOH programs implemented by Kaiser Permanente and Boston Medical Center showcase how supporting clinicians with real-time SDOH data can lead to patient-centric care. Create a 360-Degree Patient View Through TechnologyThe Office of the National Coordinator for Health Information Technology (ONC)indicatesthat the “collection, documentation, reporting, access, and use of SDOH data … can be used t...
Source: Australian Health Information Technology - October 1, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Fight Aging! Newsletter, September 12th 2022
Discussion of Present Drug Development to Target Senescent Cells Targeting Senescent Cells to Better Address Cancer and Consequences of Cancer Therapy Calorie Restriction Suppresses Generation of Immune Cells via Changes to the Gut Microbiome Arguing for an Expansion of the Hallmarks of Aging https://www.fightaging.org/archives/2022/09/arguing-for-an-expansion-of-the-hallmarks-of-aging/ The hallmarks of aging form a catalog of largely better studied changes in cells and tissues considered relevant, and possibly more important, in the onset and development of age-related degeneration and disease. This i...
Source: Fight Aging! - September 11, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Weekly Overseas Health IT Links –10th September, 2022.
This article is adapted fromVoices in the Code: A Story About People, Their Values, and the Algorithm They Made,out Sept. 8 from Russell Sage Foundation Press.In May 2021, I got a call I never expected. I was working on abook about A.I. ethics, focused on the algorithm that gives out kidneys to transplant patients in the United States. Darren Stewart —a data scientist from UNOS, the nonprofit that runs the kidney allocation process—was calling to get my take: How many decimal places should they include when calculating each patient’s allocation score? The score is an incredibly important number, given it determines w...
Source: Australian Health Information Technology - September 10, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Weekly Overseas Health IT Links –3rd September, 2022.
Here are a few I came across last week.Note: Each link is followed by a title and few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment-----https://healthitanalytics.com/news/machine-learning-tools-predict-post-op-complications-surgery-durationMachine-Learning Tools Predict Post-Op Complications, Surgery DurationResearchers from Washington University in St. Louis have developed machine-learning tools that can predict post-operative complications and surgery duration using perioperative data.ByShania K...
Source: Australian Health Information Technology - September 3, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
August 25, 2022 Edition-----The big story this week has been the multiple PM story in Australia with ScoMo. What an amazing saga!In the UK there seems to be an impending collapse of the economy coming unless some-one takes some really smart steps real soon now.Relatively the US has seemed pretty calm this week – just waiting for an impending recession – along with China and Europe.Fair to say things globally are pretty messy!-----Major Issues.-----https://www.afr.com/markets/equity-markets/every-investing-trend-misfires-as-stock-bears-are-crushed-20220814-p5b9o2Every investing trend misfires as stock bears are crushedD...
Source: Australian Health Information Technology - August 25, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs