Cardiomyopathy
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5285 records returned
Black Mothers at Increased Risk for Cardiomyopathy (CME/CE)
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African-American women have an increased risk of peripartum cardiomyopathy, researchers have found. (Source: MedPage Today State Required CME)
Source: MedPage Today State Required CME - February 9, 2010 Category: Consumer Health News Source Type: news
ICD Therapy in Children and Young Adults: Low Incidence of Inappropriate Shock Delivery
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Conclusions:In children and young adults receiving ICD therapy, the combination of strategies to prevent ventricular arrhythmias using specific drug therapy, ablation procedures, and individual programming with improved devices and leads causes a low incidence of inappropriate shock delivery. (PACE 2010; 1[ndash]8) (Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - February 9, 2010 Category: Cardiology Authors: MICHA P. BOTSCH, BIRGIT FRANZBACH, BERND OPGEN-RHEIN, FELIX BERGER, JOACHIM C. WILL Source Type: journals
African Americans have highest risk of peripartum cardiomyopathy
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African American women have much higher odds of developing peripartum cardiomyopathy than non-African Americans, a new US study shows; the findings illustrate that race is by far the largest risk...
For complete story visit theheart.org. (Source: theHeart.org)
Source: theHeart.org - February 8, 2010 Category: Cardiology Source Type: info
Scoliosis Surgery in Children With Neuromuscular Disease: Findings From the US National Inpatient Sample, 1997 to 2003 [Original Contribution]
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Conclusion Children with NMD have increased hospital length of stay and higher in-hospital mortality associated with scoliosis surgery, highlighting the need for further study of measures that could reduce complications and improve outcomes in this population. (Source: Archives of Neurology)
Source: Archives of Neurology - February 8, 2010 Category: Neurology Authors: Barsdorf, A. I., Sproule, D. M., Kaufmann, P. Tags: Neurology, Neuromuscular diseases, Pediatric Neurology, Statistics and Research Methods, Surgery, Surgical Interventions, Orthopedic Surgery, Prognosis/ Outcomes Original Contribution Source Type: journals
Sudden death caused by chronic Chagas disease in a non-endemic country: Autopsy report
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Chagas disease is a tropical disease that is prevalent in Latin America. Described herein is an autopsy case of the sudden death of a 48-year-old Brazilian man who had stayed in Japan for 7 years. The man, who had a history of Chagas disease, collapsed unexpectedly at work. Because the cause of death was unknown, forensic autopsy examination was performed. As gross findings, the heart was dilated and rounded with an increase in size and weight. The esophagus and large intestine were dilated moderately, with extensive interstitial inflammatory infiltration in the cardiac muscle, but no apparent parasite nest was observed in...
Source: Pathology International - February 8, 2010 Category: Pathology Authors: Fumiko Satoh, Hiroshi Tachibana, Iwao Hasegawa, Motoki Osawa Source Type: journals
The normal and abnormal owl monkey (Aotus sp.) heart: looking at cardiomyopathy changes with echocardiography and electrocardiography
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Conclusions Aged Aotus had increased left ventricular posterior wall thickness over young animals. Left ventricular diameter and ejection fraction appeared to be the best identifying measurements for cardiomyopathy. There were no differences in the ECG. (Source: Journal of Medical Primatology)
Source: Journal of Medical Primatology - February 8, 2010 Category: Research Authors: Rashmi S. Rajendra, Alan G. Brady, Virginia L. Parks, Clara V. Massey, Susan V. Gibson, Christian R. Abee Source Type: journals
Echocardiography of the Right Ventricle in Athlete's Heart and Hearts of Normal Size Compared to Magnetic Resonance Imaging: Which Measurements Should be Applied in Athletes?
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In conclusion, two-dimensional echocardiographic RV measurements offer only a limited potential to reflect true RV dimensions. Only RV-EDD may differentiate between normal hearts and exercise related RV adaptations in AH, and is the only recommendable parameter to be measured in athletes routinely. In unclear cases additional methods should be used to examine the RV in athletes.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents | Abstract | Full text (Source: International Journal of Sports Medicine)
Source: International Journal of Sports Medicine - February 5, 2010 Category: Sports Medicine Tags: Clinical Sciences Source Type: journals
Usefulness of Cardiac Resynchronization Therapy in Patients With Adriamycin-Induced Cardiomyopathy
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In conclusion, patients with AIC may derive a significant echocardiographic and symptomatic benefit from CRT, which is similar to that seen in other forms of NIC. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 5, 2010 Category: Cardiology Authors: John Rickard, Dharam J. Kumbhani, Bryan Baranowski, David O. Martin, Wilson H. Tang, Bruce L. Wilkoff Tags: Heart Failure Source Type: journals
Morphologic Features of Exertional Versus Nonexertional Sudden Death in Patients With Hypertrophic Cardiomyopathy
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In conclusion, there are no pathologic features that would identify patients with HC at risk for exertional death. Because relatively decreased heart weight is strongly associated with exertional death, and because a large proportion of exertional deaths with HC are not associated with significant asymmetry, cardiologists should be careful in excluding the diagnosis of HC in athletes with even mild degrees of cardiomegaly, especially young men. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 5, 2010 Category: Cardiology Authors: Fabio Tavora, Nathaniel Cresswell, Ling Li, Mary Ripple, David Fowler, Allen Burke Tags: cardiomyopathy Source Type: journals
When we talk about Duchenne, we tend to focus on our sons. But there is a journey that women go on as mothers, daughters, sisters and as carriers. Read PPMD President Pat Furlong’s latest blog, about how Duchenne affects women, not just emotionally but physically.patfurlongsblog.blogspot.com
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It was a long time ago that I sat in the exam room and received the diagnosis. My boys had Duchenne. The diagnosis was followed by a series of questions about my family history, the doctor assuming that somewhere along the line, there was another boy long ago. In my case, there was no history. None. I asked every living member of my mother’s family what they knew, if there was someone who had an unnamed ‘problem’, someone who was weak, or a child who died young from an unnamed illness. One of my cousins talked about my "crazy Uncle Harry” who fell off the roof, but it hardly fit the picture I was looking for. I had...
Source: Parent Project Muscular Dystrophy - February 5, 2010 Category: Neurology Authors: (author unknown) Source Type: organizations
De novo triple segmental aneuploid of 1p, 1q, and 4q in a girl with hypertrophic cardiomyopathy, muscle hypotonia, and multiple congenital anomalies
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(Source: American Journal of Medical Genetics Part A)
Source: American Journal of Medical Genetics Part A - February 5, 2010 Category: Genetics & Stem Cells Authors: Gwo-Chin Ma, Yu-Yuan Ke, Meng-Luen Lee, Long-Yen Tsao, Dong-Jay Lee, Chin-Wen Yang, Shou-Jen Kuo, Han-Yao Chiu, Ming Chen Source Type: journals
Takotsubo Cardiomyopathy as an Underlying Mediator of Myocardial Infarction with Normal Coronary Arteries
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Cardiology 2010;115:186190 (DOI:10.1159/000280810) (Source: Karger Publishers)
Source: Karger Publishers - February 4, 2010 Category: Cancer & Oncology Source Type: journals
Authors' response
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(Source: Heart)
Source: Heart - February 4, 2010 Category: Cardiology Authors: Sheppard, M. N. Tags: Hypertrophic cardiomyopathy, Drugs: cardiovascular system Featured correspondence Source Type: journals
Reply
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We appreciate the correspondence from Dr. Murgo, stimulated by our recent historical review focused on the evolving understanding of left ventricular (LV) outflow gradients in hypertrophic cardiomyopathy (HCM) (). Dr. Murgo has had an important role in this conversation, which has spanned virtually the last 5 decades (), for this heterogeneous disease with complex ejection dynamics (). (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - February 4, 2010 Category: Cardiology Authors: Barry J. Maron, Martin S. Maron, E. Douglas Wigle, Eugene Braunwald Tags: Letters to the Editor Source Type: journals
Have We Really Come to Understand the Relationship Between the Left Ventricular Outflow Tract Gradient and Left Ventricular Emptying in Hypertrophic Cardiomyopathy?
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In the recent review of hypertrophic cardiomyopathy (HCM) by Maron et al. (), historical controversies relating to the relationship between left ventricular outflow tract (LVOT) pressure gradients and left ventricular (LV) ejection dynamics are revisited. The crux of these controversies is an assumption that the very presence of such gradients negatively impacts LV emptying (outflow) in obstructive HCM. (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - February 4, 2010 Category: Cardiology Authors: Joseph P. Murgo Tags: Letters to the Editor Source Type: journals
Compound and Digenic Heterozygosity Contributes to Arrhythmogenic Right Ventricular Cardiomyopathy
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Conclusions: These data suggest that the genetic basis of ARVC includes reduced penetrance with compound and digenic heterozygosity. Disturbed junctional cytoarchitecture in subjects with desmosomal mutations confirms that ARVC is a disease of the desmosome and cell junction. (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - February 4, 2010 Category: Cardiology Authors: Tianhong Xu, Zhao Yang, Matteo Vatta, Alessandra Rampazzo, Giorgia Beffagna, Kalliopi Pillichou, Steven E. Scherer, Jeffrey Saffitz, Joshua Kravitz, Wojciech Zareba, Gian Antonio Danieli, Alessandra Lorenzon, Andrea Nava, Barbara Bauce, Gaetano Thiene, Cr Tags: Heart Rhythm Disorders Source Type: journals
Significance of Maximal and Regional Left Ventricular Wall Thickness in Association With Arrhythmic Events in Patients With Hypertrophic Cardiomyopathy.
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Conclusions: Non-invasive imaging measures, such as LVWT, do have a role in identifying the patients at risk of VAEs. In addition to maximal LVWT, the key regional LVWTs provide complementary information of incremental value to the conventional risk stratification model.
PMID: 20134097 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - February 4, 2010 Category: Cardiology Authors: Puntmann VO, Yap YG, McKenna W, Camm AJ Tags: Circ J Source Type: journals
Impaired Cardiovascular Function in Primary Biliary Cirrhosis.
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Conclusion: Our findings suggest the presence of altered myocardial function in PBC. Autonomic "dysfunction" may, rather than being an abnormal process, represent a compensatory mechanism to increase cardiac return to mitigate these effects.
PMID: 20133949 [PubMed - as supplied by publisher] (Source: Am J Physiol Gastroi...)
Source: Am J Physiol Gastroi... - February 4, 2010 Category: Gastroenterology Authors: Jones DE, Hollingsworth KG, Fattakhova G, Macgowan GA, Taylor R, Blamire AM, Newton JL Tags: Am J Physiol Gastrointest Liver Physiol Source Type: journals
Are Electrocardiographic Changes in Patients with Acute Subarachnoid Hemorrhage Associated with Takotsubo Cardiomyopathy?
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Cardiology 2010;115:182183 (DOI:10.1159/000280396) (Source: Karger Publishers)
Source: Karger Publishers - February 3, 2010 Category: Cancer & Oncology Source Type: journals
Genetic and ultrastructural studies in dilated cardiomyopathy patients: a large deletion in the lamin A/C gene is associated with cardiomyocyte nuclear envelope disruption
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In this study, we screened a series of 25 unrelated DCM patient
samples for (a) cardiomyocyte nuclear abnormalities and (b) mutations in LMNA and TMPO as they are two DCM-causing genes that encode proteins involved in maintaining nuclear envelope architecture. Among the 25
heart samples investigated, we identified major cardiomyocyte nuclear abnormalities in 8 patients. Direct sequencing allowed
the detection of three heterozygous LMNA mutations (p.D192G, p.Q353K and p.R541S) in three patients. By multiplex ligation-dependant probe amplification (MLPA)/quantitative
real-time PCR, we found a heterozygous deletion encomp...
Source: Basic Research in Cardiology - February 3, 2010 Category: Cardiology Tags: Basic Research in Cardiology Source Type: journals
Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging
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In conclusion, conditional expression of I-1c or I-1S67A enhanced steady-state phosphorylation of 2 key Ca2+-regulating sarcoplasmic reticulum enzymes. This was associated with increased contractile function in young animals but also with arrhythmias and cardiomyopathy after adrenergic stress and with aging. These data should be considered in the development of novel therapies for heart failure. (Source: Journal of Clinical Investigation)
Source: Journal of Clinical Investigation - February 2, 2010 Category: Biomedical Science Authors: Katrin Wittköpper, Larissa Fabritz, Stefan Neef, Katharina R. Ort, Clemens Grefe, Bernhard Unsöld, Paulus Kirchhof, Lars S. Maier, Gerd Hasenfuss, Dobromir Dobrev, Thomas Eschenhagen, Ali El-Armouche Source Type: journals
Stomach Pierced by Apical Cuff late after Removal of Toyobo Assist Device [CASE STUDIES]
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A 38-year-old woman suffering from dilated cardiomyopathy underwent successful removal of a Toyobo left ventricular assist device after 11 months of support. Four months later, discharge of pus from the skin resulted from the contaminated residual apical cuff. The purulence stopped spontaneously 16 months later, but halitosis then developed. Two weeks later, fever and hematemesis occurred. Emergency surgery revealed gastric perforation by the apical cuff, which was removed under cardiopulmonary bypass. (Source: Asian Cardiovascular and Thoracic Annals)
Source: Asian Cardiovascular and Thoracic Annals - February 2, 2010 Category: Cardiology Authors: Nawata, Kyo, Ono, Motomura, Takamoto Tags: CASE STUDIES Source Type: journals
Takotsubo Cardiomyopathy, or Broken-Heart Syndrome (March).
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CONCLUSIONS: Takotsubo cardiomyopathy causes a reversible left ventricle dysfunction which occurs most commonly in postmenopausal women with or without cardiovascular disease. Recognition is detected with coronary angiography. It is thought to primarily be due to an abnormally high sympathetic stimulation after emotional or psychological stress. Treatment consists of an angiotensin converting enzyme inhibitor and/or beta blocker if needed for left ventricular dysfunction and possibly an anxiolytic agent.
PMID: 20124462 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - February 2, 2010 Category: Drugs & Pharmacology Authors: Nykamp D, Titak JA Tags: Ann Pharmacother Source Type: journals
Clinical practice
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Abstract The current maintenance treatment for children with heart failure remains controversial: To a large extent, it is based on
extrapolation of data derived from trials in adult populations. There are only a few randomized trials focused on the treatment
of children with cardiac disease, especially in the subgroup with cardiomyopathy and heart failure. The goals of therapy are
to maintain circulatory and end-organ function and to allow for recovery and reverse remodeling to occur. When maintenance
therapy fails and medical treatment does not result in clinical improvement, the alternative of device ther...
Source: European Journal of Pediatrics - February 1, 2010 Category: Pediatrics Tags: European Journal of Pediatrics Source Type: journals
Journal Scan: Optimizing Hemodynamics in Heart Failure Patients by Systematic Screening of Left Ventricular Pacing Sites: The Lateral Left Ventricular Wall and the Coronary Sinus Are Rarely the Best Sites (J Am Coll Cardiol 2010;55:566-575.)
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Thirty-five patients (mean age 63 years) with a nonischemic cardiomyopathy (mean ejection fraction 28%) and left bundle branch block underwent hemodynamic measurements during dual-chamber (DDD) pacing from a lateral branch of the coronary sinus (CS) and at 10 prespecified endocardial LV sites. Hemod. . . (Source: Cardiosource)
Source: Cardiosource - February 1, 2010 Category: Cardiology Source Type: organizations
Clinical Approach to Sudden Cardiac Death Syndromes
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Clinical cardiologists are encountering an important challenge in the care of families with inherited cardiac diseases. The majority of the inherited cardiac diseases causing sudden death express themselves at variable ages in the form of altered muscle function – for instance hypertrophic or dilated cardiomyopathy – or in the form of arrhythmias, including Brugada syndrome and long QT ... (Source: Springer Medicine titles)
Source: Springer Medicine titles - February 1, 2010 Category: Databases & Libraries Tags: Cardiology Source Type: organizations
Right ventricular hypertrophy and scarring in mutation positive hypertrophic cardiomyopathy
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(Source: European Heart Journal)
Source: European Heart Journal - February 1, 2010 Category: Cardiology Authors: Keeling, A. N., Carr, J. C., Choudhury, L. Tags: CARDIOVASCULAR FLASHLIGHTS Source Type: journals
Atrial fibrillation and long-term prognosis in patients hospitalized for heart failure: results from heart failure survey in Israel (HFSIS)
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Conclusion
AF was present in a third of hospitalized HF patients, and identified a population with increased mortality risk, largely due to co-morbidities. (Source: European Heart Journal)
Source: European Heart Journal - February 1, 2010 Category: Cardiology Authors: Shotan, A., Garty, M., Blondhein, D. S., Meisel, S. R., Lewis, B. S., Shochat, M., Grossman, E., Porath, A., Boyko, V., Zimlichman, R., Caspi, A., Gottlieb, S., for the HFSIS Steering Committee and Investigators Tags: Heart failure/cardiomyopathy Source Type: journals
The role of oestrogen in the pathophysiologic process of the Tako-Tsubo cardiomyopathy
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(Source: European Heart Journal)
Source: European Heart Journal - February 1, 2010 Category: Cardiology Authors: Sclarovsky, S., Nikus, K. C. Tags: LETTERS TO THE EDITOR Source Type: journals
The role of oestrogen in the pathophysiologic process of the Tako-Tsubo cardiomyopathy: reply
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(Source: European Heart Journal)
Source: European Heart Journal - February 1, 2010 Category: Cardiology Authors: Nef, H. M., Hamm, C. W., Mollmann, H. Tags: LETTERS TO THE EDITOR Source Type: journals
Echocardiography in stress cardiomyopathy and acute LVOT obstruction
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Abstract Widespread use of echocardiography has contributed to more frequent recognition of takotsubo stress cardiomyopathy. Initial
presentation is similar to acute coronary syndrome and the acute course can be complicated by heart failure, arrhythmias,
dynamic left ventricular outflow tract obstruction, hypotension and death. We briefly review the clinical presentation and
propose a unified diagnostic algorithm for cardiologists acutely managing this cardiac emergency. We highlight the central
role of echocardiography and emphasize the nuances of this peculiar acute cardiomyopathy from an echocardiographer...
Source: The International Journal of Cardiovascular Imaging - February 1, 2010 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals
Incontinetia pigmenti-related myopathy or unsolved “double trouble”?
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This report highlights the unusual combination of a genetically confirmed incontinentia pigmenti and a proximal myopathy and dilatative cardiomyopathy of unknown origin. We discuss that the striated muscle involvement (i) might be based on the observed intragenic deletion of the NEMO gene, or (ii) on an additional gene defect leading to an adult onset myopathy. Further studies on neuromuscular involvement in patients with incontinentia pigmenti are needed to clarify this issue. (Source: Neuromuscular Disorders)
Source: Neuromuscular Disorders - February 1, 2010 Category: Neurology Authors: H.B. Huttner, G. Richter, A. Jünemann, W. Kress, J. Weis, J.M. Schröder, A. Gal, A. Doerfler, B. Udd, R. Schröder Tags: Research papers Source Type: journals
Bradycardiomyopathy: The Case for a Causative Relationship Between Severe Sinus Bradycardia and Heart Failure
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Bradycardiomyopathy. A 28-year-old man presented with progressive fatigue. Physical examination and ECG revealed severe sinus bradycardia. Echocardiography showed features of noncompaction cardiomyopathy and moderate aortic valve regurgitation. We hypothesized that the chronic volume overload exaggerated by prolonged diastole due to the bradycardia resulted in heart failure and noncompaction cardiomyopathy look-alike features. After implantation of an AAI pacemaker, his symptoms and signs of cardiomyopathy were fully recovered. (J Cardiovasc Electrophysiol, Vol. pp. 1-3) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 1, 2010 Category: Cardiology Authors: KADIR CALISKAN, AGGIE H.M.M. BALK, LUC JORDAENS, TAMAS SZILI-TOROK Source Type: journals
Implantable Cardioverter-Defibrillator in Patients With Hypertrophic Cardiomyopathy: Efficacy and Complications of the Therapy in Long-Term Follow-up
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Conclusion: ICD therapy is effective in SCD prevention in patients with HCM, although the complication rate is significant. Nonsustained ventricular tachycardia seems to be the most predictive RF for appropriate device discharges. Number of RF did not impact the incidence of appropriate ICD interventions. (J Cardiovasc Electrophysiol, Vol. pp. 1-7) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 1, 2010 Category: Cardiology Authors: PAWEŁ SYSKA, ANDRZEJ PRZYBYLSKI, LIDIA CHOJNOWSKA, MICHAŁ LEWANDOWSKI, MACIEJ STERLIŃSKI, ALEKSANDER MACIĄG, KATARZYNA GEPNER, MARIUSZ PYTKOWSKI, ILONA KOWALIK, RENATA MĄCZYŃSKA-MAZURUK, WITOLD RUZYŁŁ Source Type: journals
Ductus venosus blood flow velocity waveform in diabetic pregnancies.
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CONCLUSION:: Diabetic pregnancies exhibit increased PI-DV values when compared to a normal low risk pregnant population, possibly indicating fetal cardiac affection. Copyright (c) 2010 ISUOG. Published by John Wiley & Sons, Ltd.
PMID: 20127749 [PubMed - as supplied by publisher] (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - February 1, 2010 Category: Radiology Authors: Stuart A, Amer-Wåhlin I, Gudmundsson S, Maršál K, Thuring A, Källen K Tags: Ultrasound Obstet Gynecol Source Type: journals
Metabolic Remodeling Associated With Subchronic Doxorubicin Cardiomyopathy.
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Doxorubicin (Adriamycin(R)) is a potent and broad-spectrum antineoplastic agent, the clinical utility of which is restricted by a cumulative and progressive cardiomyopathy that develops with repeated dosing. Fundamental to the cardiac failure is an interference with mitochondrial respiration and inhibition of oxidative phosphorylation. Global gene expression arrays in cardiac tissue indicate that inhibition of mitochondrial oxidative phosphorylation by doxorubicin (DOX) is accompanied by a decreased expression of genes related to aerobic fatty acid oxidation and a corresponding increase in expression of genes involved ...
Source: Toxicology - February 1, 2010 Category: Toxicology Authors: Carvalho RA, Sousa RP, Cadete VJ, Lopaschuk GD, Palmeira CM, Bjork JA, Wallace KB Tags: Toxicology Source Type: journals
Diastolic Myocardial Mechanics in Hypertrophic Cardiomyopathy
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Conclusions: The evaluation of biplane myocardial mechanics offers new insights into the evaluation of diastolic function and its relationship to clinical status. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - February 1, 2010 Category: Cardiology Authors: Shemy Carasso, Hua Yang, Anna Woo, Michal Jamorski, E. Douglas Wigle, Harry Rakowski Tags: Clinical Investigations Source Type: journals
Corrigendum
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An error occurred in Figure 4 (D), in “Diastolic dysfunction and its histopathological correlation in obstructive hypertrophic cardiomyopathy in children and adolescents” by Menon SC, Eidem BW, Dearani JA, Ommen SR, Ackerman MJ, Miller D.; published in issue 22(12): 1331 of Journal of the American Society of Echocardiography. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - February 1, 2010 Category: Cardiology Tags: Case Reports Source Type: journals
Cardiac manifestations of neuromuscular disorders in children
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Summary: Cardiac abnormalities occur in association with many of the neuromuscular disorders that present in childhood. Genetic defects involving the cytoskeleton, nuclear membrane, and mitochondrial function have all been described in patients with skeletal myopathy and cardiac involvement. The most common classes of neuromuscular disorders with cardiac manifestations are the muscular dystrophies- Duchenne, Becker, limb-girdle and Emery Dreifuss. Friedreich Ataxia and myotonic dystrophy also have important cardiac involvement. The type and extent of cardiac manifestations are specific to the type of neuromuscular disorder...
Source: Paediatric Respiratory Reviews - January 29, 2010 Category: Respiratory Medicine Authors: Daphne T. Hsu Tags: Mini-symposium: Cardio-respiratory considerations Source Type: journals
Med Sci Monit 2010; 16(2):CS11-14 "High dose immune globulin therapy ameliorates peripartum cardiomyopathy with elevated serum antibody titer to influenza virus: Case report of two patients"
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Conclusions: These cases suggest that viral infection including influenza contributes to PPCM and that high doses of immunoglobulin constitute an effective treatment for this disorder. (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 29, 2010 Category: Research Source Type: journals
Takotsubo Cardiomyopathy: A Review of the Literature
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Although takotsubo cardiomyopathy is a rare entity, it is an important differential in patients presenting with symptoms, signs, and electrocardiographic changes suggestive of an acute myocardial infarction. Since it was first recognized in 1991, it has gained increasing attention worldwide; however, its etiology and consequently the optimal management still remains unclear. Here, the authors provide a review of the current literature accompanied with images of a typical case from our department. (Source: Angiology)
Source: Angiology - January 29, 2010 Category: Cardiology Authors: Pernicova, I., Garg, S., Bourantas, C. V., Alamgir, F., Hoye, A. Tags: Articles Source Type: journals
Ability of a 5-Minute Electrocardiography (ECG) for Predicting Arrhythmias in Doberman Pinschers with Cardiomyopathy in Comparison with a 24-Hour Ambulatory ECG
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Ventricular premature contractions (VPCs) are common in the occult stage of cardiomyopathy in Doberman Pinschers. Although the gold standard for detecting arrhythmia is the 24-hour ambulatory electrocardiography (ECG) (Holter), this method is more expensive, time-consuming and often not as readily available as common ECG. Comparison of 5-minute ECGs with Holter examinations. Eight hundred and seventy-five 5-minute ECGs and Holter examinations of 431 Doberman Pinschers. Each examination included a 5-minute ECG and Holter examination. A cut-off value of >100 VPCs/24 hours using Holter was considered diagnostic for the presen...
Source: Journal of Veterinary Internal Medicine - January 29, 2010 Category: Veterinary Research Authors: G. Wess, A. Schulze, N. Geraghty, K. Hartmann Source Type: journals
Review: Risk stratification and prevention of sudden death in hypertrophic cardiomyopathy
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Source: Circulation
Area: News
This review in Circulation on risk stratification and prevention of sudden death in hypertrophic cardiomyopathy covers the following topics:
. Epidemiology of sudden death
. Arrhythmogenic substrate
. Sudden death prevention: historical context
. Implantable cardioverter-defibrillator (ICD) experience in hypertrophic cardiomyopathy
. Unpredictable substrate
. Selection of patients for ICDs
. Translating risk factors to clinical practice
. Other considerations affecting ICDs
. Strategies for sudden death prevention: Targe...
Source: NeLM - News - January 29, 2010 Category: Drugs & Pharmacology Source Type: organizations
Carvedilol may alleviate late cardiac remodelling following surgical ventricular restoration [Original articles]
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Conclusions: High-dose carvedilol alleviated LV remodelling and diastolic dysfunction following SVR accompanying with reduction in myocardial fibrosis. Blockade of β-adrenergic receptor may be a promising adjuvant therapy in patients following SVR. (Source: European Journal of Cardio-Thoracic Surgery)
Source: European Journal of Cardio-Thoracic Surgery - January 28, 2010 Category: Cardiovascular & Thoracic Surgery Authors: Yoshikawa, E., Marui, A., Tsukashita, M., Nishina, T., Wang, J., Muranaka, H., Ikeda, T., Komeda, M. Tags: Congestive Heart Failure, Coronary disease, Myocardial infarction Original articles Source Type: journals
Destination therapy with a rotary blood pump and novel power delivery [Original articles]
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Conclusions: From this learning-curve experience, both left ventricular assist device (LVAD) and power delivery are reliable and promising for destination therapy. Early mortality is similar to other studies and relates to the severity of illness. Pump infection has not occurred and prolonged event-free survival is clearly possible with expert medical management. (Source: European Journal of Cardio-Thoracic Surgery)
Source: European Journal of Cardio-Thoracic Surgery - January 28, 2010 Category: Cardiovascular & Thoracic Surgery Authors: Westaby, S., Siegenthaler, M., Beyersdorf, F., Massetti, M., Pepper, J., Khayat, A., Hetzer, R., Frazier, O. H. Tags: Mechanical Circulatory Assistance Original articles Source Type: journals
HLA class II polymorphisms in Tunisian patients with dilated cardiomyopathy
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In conclusion, our data suggest that the variation in class II HLA alleles could be a genetic factor involved in the susceptibility to primary DCM in the Tunisian population. (Source: Tissue Antigens)
Source: Tissue Antigens - January 28, 2010 Category: Allergy & Immunology Authors: S. Mahjoub, S. Mehri, E. Ghazouani, F. Ouarda, R. Boussada, A. Zaroui, R. Mechmeche, M. Hammami, S. Ben Arab Source Type: journals
Clinical features and outcomes in 348 patients with polyarteritis nodosa: A systematic retrospective study of patients diagnosed between 1963 and 2005 and entered into the French vasculitis study group database
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This study was undertaken to describe the main characteristics of and long-term outcomes in patients with well-characterized PAN diagnoses.We conducted a systematic retrospective study of 348 patients who were diagnosed as having PAN between March 1963 and October 2005, were registered in the French Vasculitis Study Group database, and satisfied the American College of Rheumatology and CHCC criteria. Patient characteristics and outcomes were analyzed and compared according to hepatitis B virus (HBV) status.At diagnosis, the mean ± SD age was 51.2 ± 17.3 years. The most frequent findings were general symptoms (93.1%), neu...
Source: Arthritis and Rheumatism - January 28, 2010 Category: Rheumatology Authors: Christian Pagnoux, Raphaèle Seror, Corneliu Henegar, Alfred Mahr, Pascal Cohen, Véronique Le Guern, Boris Bienvenu, Luc Mouthon, Loïc Guillevin, French Vasculitis Study Group Tags: Vasculitis Source Type: journals
Abnormal response to mental stress in patients with Takotsubo cardiomyopathy detected by gated single photon emission computed tomography
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Conclusion Mental stress may evoke regional and/or global abnormalities in most TTC patients. The abnormal response to mental stress
supports the role of sympathetic stimulation in TTC. Mental stress could thus be helpful for TTC evaluation.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1362-zAuthors
Roberto Sciagrà, University of Florence Nuclear Medicine Unit, Department of Clinical Physiopathology Viale Morgagni 85 50134 Florence ItalyGuido Parodi, Careggi Hospital Division of Cardiology Florence ItalyStefano Del Pace, Careggi Hospital Department of Heart and Vessels, ...
Source: European Journal of Nuclear Medicine and Molecular Imaging - January 27, 2010 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Combined heart and liver transplantation on cardiopulmonary bypass: report of four cases.
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CONCLUSION: Combined heart and liver transplant during cardiopulmonary bypass is a viable strategy that may confer benefit to this unique type of patient.
PMID: 20107943 [PubMed - as supplied by publisher] (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - January 27, 2010 Category: Anesthesiology Authors: Hennessey T, Backman SB, Cecere R, Lachapelle K, de Varennes B, Ergina P, Metrakos P, Schricker T Tags: Can J Anaesth Source Type: journals
Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy [Medical_Sciences]
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Patients with Duchenne muscular dystrophy (DMD) have a progressive dilated cardiomyopathy associated with fatal cardiac arrhythmias. Electrical and functional abnormalities... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - January 26, 2010 Category: Science Authors: Fauconnier, J., Thireau, J., Reiken, S., Cassan, C., Richard, S., Matecki, S., Marks, A. R., Lacampagne, A. Tags: Medical_Sciences Source Type: journals
