Query: cerebral palsy
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21101 records returned
Adolescent use of helmets moped riders in the city of Gerona, Spain, 2006. - Pumarola CF, Pérez ME, Font-Mayolas S, Noguer CB, Ferrando DB, Canal DJ.
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BACKGROUND: Cerebral injuries as a result of craniocerebral trauma are the most frequent cause of death in traffic collisions involving two-wheeled vehicles. In spite of the proven effectiveness of the use of the head protective devices to prevent injuries...
Source: SafetyLit: All (Unduplicated) - February 7, 2010 Category: Global & Universal Tags: Age: Adolescents Source Type: info
The role of the dopamine transporter DAT1 genotype on the neural correlates of cognitive flexibilityEmail this article to a colleague.
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Cognitive flexibility, the ability to adapt goal-oriented behaviour in response to changing environmental demands, varies widely amongst individuals, yet its underlying neural mechanisms are not fully understood. Neuropharmacological and human clinical studies have suggested a critical role for striatal dopaminergic function mediated by the dopamine transporter (DAT). The present study aimed at revealing the role of the DAT in the individual brain response stereotypy underlying cognitive flexibility. A task-switching protocol was administered to a sample divided according to the presence or absence of the 9-repeat (9R) all...
Source: European Journal of Neuroscience - February 6, 2010 Category: Neuroscience Authors: M. Garcia-Garcia, F. Barceló, I. C. Clemente, C. Escera Source Type: journals
Patient selection for revascularization procedures in adult Moyamoya disease based on dynamic perfusion computerized tomography with acetazolamide challenge (PCTA)Email this article to a colleague.
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Abstract The usefulness of dynamic perfusion computerized tomography for early diagnosis of stroke is well established. However, limited
data exists to assess the value of PCT in the evaluation of patients with chronic cerebral ischemia. The purpose of the study
was to assess the utility of perfusion computerized tomography with acetazolamide challenge (PCTA) in the evaluation of cerebral
perfusion and cerebrovascular reserve (CVR) in adult Moyamoya patients. From 2005–2008, 41 patients with Moyamoya were scrutinized
by PCTA. Of these, 22 patients (12 females, ten males, mean age 41 years) with ischem...
Source: Urosurgical Review - February 5, 2010 Category: Urology & Nephrology Tags: Neurosurgical Review Source Type: journals
Remote cerebral hematomas in patients treated with intravenous rt-PAEmail this article to a colleague.
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We report our experience in patients treated with intravenous rt-PA. We reviewed our database of consecutive patients
treated at our hospital from 1999 to 2008. We used the inclusion/exclusion criteria of the ECASS-2 study from 1999 to 2003,
and the criteria of the SITS-MOST study since 2004. A follow-up CT scan was obtained in all of the patients within the first
36 h of treatment. Cerebral hemorrhagic complications were classified as hemorrhagic infarction (HI-1/HI-2) and parenchymal
hematoma (PH-1/PH-2). The rPH was defined as any extra-ischemic hemorrhagic lesion observed in the follow-up CT. A favorable
outc...
Source: Journal of Neurology - February 5, 2010 Category: Neurology Tags: Journal of Neurology Source Type: journals
Low back pain associates with altered activity of the cerebral cortex prior to arm movements that require postural adjustmentEmail this article to a colleague.
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Conclusions: Cerebrocortical activity becomes altered prior to arm movements requiring APAs for individuals with chronic LBP.Significance: These results support a theoretical model that altered central motor neurophysiology associates with LBP, thereby implying that rehabilitation strategies should address these neuromotor impairments.
Source: Clinical Neurophysiology - February 5, 2010 Category: Neuroscience Authors: Jesse V. Jacobs, Sharon M. Henry, Keith J. Nagle Tags: Original Research Articles Source Type: journals
P1 and P2 components of human visual evoked potentials are modulated by depth perception of 3-dimensional imagesEmail this article to a colleague.
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Conclusions: The difference in P1 amplitude between two conditions can be explained by the difference between conditions, one of which yielded depth perception while the other did not, since previous studies showed that P1 and N1 are modulated by perception of images in depth. The role of P2 and the mechanism responsible for the increase in P2 amplitude during condition II remain unknown.Significance: We recorded VEPs and identified electrophysiological correlates of depth perception with 3D images produced by concave/convex figures.
Source: Clinical Neurophysiology - February 5, 2010 Category: Neuroscience Authors: Shu Omoto, Yoshiyuki Kuroiwa, Saika Otsuka, Yasuhisa Baba, Chuanwei Wang, Mei Li, Nobuhisa Mizuki, Naohisa Ueda, Shigeru Koyano, Yume Suzuki Tags: Original Research Articles Source Type: journals
Treating consciousness with caution | Ken MasonEmail this article to a colleague.
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We should be wary of building ethics around patients in permanent vegetative states, as this is a relatively new scienceProminent among the attitudes to the case that Professor McLean and I share is that it is easy to fall into the trap of making a premature judgment when confronted with a story of such potential ethico-legal significance. It raises issues that merit prolonged analysis not only as to its implications but also as to its factual basis. I would prefer, however, to treat the announcement as a cautionary tale.From time to time, movements are mounted that seek to recognise death in terms of "cognitive" or neocor...
Source: Guardian Unlimited Science - February 5, 2010 Category: Science Authors: Ken Mason Tags: Neuroscience Health Health policy Medical research UK news guardian.co.uk Comment Comment is free Source Type: news
Quantitative MR Imaging and Spectroscopy in Congenital Cytomegalovirus Infection and Periventricular Leukomalacia Suggests a Comparable Neuropathological Substrate of the Cerebral White Matter LesionsEmail this article to a colleague.
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Neuropediatrics 2009; 40: 168-173DOI: 10.1055/s-0029-1243228AbstractCongenital (CMV) infection and periventricular leukomalacia (PVL) both lead to static cerebral white matter lesions. In contrast to PVL, the neuropathologicAL substrate of these lesions in congenital CMV is not clear. By comparing changes in quantitative magnetic resonance (MR) parameters and MR spectroscopy metabolite concentrations we wanted to determine whether the nature of the white matter pathology in congenital CMV infection could be similar to the known pathology of PVL. Diffusion parameters, apparent diffusion coefficient (ADC) and fractional anis...
Source: Neuropediatrics - February 5, 2010 Category: Neurology Tags: Original Article Source Type: journals
Congenital Infiltrating Lipomatosis of the Face with HemimegalencephalyEmail this article to a colleague.
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We present a case of unilateral facial swelling in a 1.5-year-old boy in whom magnetic resonance imaging and computed tomography revealed CILF associated with unilateral megalencephaly.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents | Abstract | Full text
Source: Neuropediatrics - February 5, 2010 Category: Neurology Tags: Short Communication Source Type: journals
Congenital and Evolving Vascular Disorders Associated with Cutaneous Hemangiomas: Case ReportEmail this article to a colleague.
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Neuropediatrics 2009; 40: 148-151DOI: 10.1055/s-0029-1239507AbstractConventional arteriography in an 11-month-old boy with cardiopathy, aortic arch coarctation and haemangiomas showed the absence of the right internal carotid and vertebral arteries, hypertrophy of the right external carotid artery, with enlargement of the internal maxillary and ophthalmic arteries that supplied the right cerebral hemisphere. An MRI study showed an infarcted area in the posterior zone of the left cerebral hemisphere vascularised by the middle cerebral artery that was caused by a thrombosis during a severe bout of gastroenteritis. MRA studie...
Source: Neuropediatrics - February 5, 2010 Category: Neurology Tags: Short Communication Source Type: journals
Fractures of the distal humerus in elderly patients treated with a ring fixatorEmail this article to a colleague.
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We present our experience with treatment
by closed reduction and external fixation with a non-bridging ring fixator in distal humerus fractures in elderly patients.
There were ten females, aged 70–89 (average 78.4). Fracture types (AO/ASIF) included three supracondylar fractures (type A)
and seven intercondylar fractures (type C). All patients were treated by closed reduction and external fixation with a non-bridging
ring fixator of the distal humerus and immediate postoperative mobilisation of the elbow. External fixation was removed on
an average of 72 days (range 62–90). All fractures united. Average time ...
Source: International Orthopaedics - February 5, 2010 Category: Orthopaedics Tags: International Orthopaedics Source Type: journals
Systemic Glucose and Brain Energy Metabolism after Subarachnoid HemorrhageEmail this article to a colleague.
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Conclusions Acute reductions in serum glucose, even to levels within the normal range, may be associated with brain energy metabolic crisis
and LPR elevation in poor-grade SAH patients.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s12028-009-9327-4Authors
Raimund Helbok, Columbia University Medical Center Division of Critical Care Neurology, Department of Neurology Milstein Hospital 8 Center, 177 Fort Washington Ave New York NY 10032 USAJ. Michael Schmidt, Columbia University Medical Center Division of Critical Care Neurology, Department of Neurology Milstein Hospital 8 Center, 177 ...
Source: Neurocritical Care - February 5, 2010 Category: Neurology Tags: Neurocritical Care Source Type: journals
Fulminant Sepsis-Associated Encephalopathy in Two Children: Serial Neuroimaging Findings and Clinical CourseEmail this article to a colleague.
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We report on two children with sepsis-associated encephalopathy. They presented with fulminant neurological damage on clinical, neuroimaging, and neurophysiological findings. At onset, both went into deep coma after status epilepticus, resulting in near brain death. Both patients showed diffuse brain edema on CT and severe brain dysfunction on electroencephalography within a day of onset. Brain magnetic resonance (MR) imaging of one patient on day 2 showed restricted diffusion in the basal ganglia and the subcortical white matter of the frontal and occipital lobes. Brain edema aggravated and lasted for a few months despite...
Source: Neuropediatrics - February 5, 2010 Category: Neurology Tags: Original Article Source Type: journals
[Editorial] Fabricated or induced illness by carers: a complex conundrumEmail this article to a colleague.
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You are asked to pay a house visit to a young boy whose medical history includes cerebral palsy, cystic fibrosis, diabetes, food allergies, and intolerance to sunlight. However, on examination, you can find nothing wrong with him. On returning to the surgery, you follow-up with the numerous consultants at the various hospitals where the boy attends. They are also baffled. The only common feature is the mother's insistence that the boy is very ill. In this tragic but true case of child maltreatment, which received wide publicity in the UK recently, doctors involved in the boy's management concluded that there was little wro...
Source: LANCET - February 5, 2010 Category: Journals (General) Authors: The Lancet Tags: Editorial Source Type: journals
IMAGING DIAGNOSIS—NEURONAL CEROID LIPOFUSCINOSIS WITH A CHRONIC SUBDURAL HEMATOMAEmail this article to a colleague.
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A subdural hematoma was found to accompany neuronal ceroid lipofuscinosis in an 11-month-old Dachshund. Results from clinical, magnetic resonance (MR) imaging, histopathologic, ultrastructural, and molecular assessments are described. The dog had a 3-month history of progressive neurologic signs. In MR images, there was severe asymmetric cerebral atrophy with a subdural hematoma. Histopathologically, there was autofluorescent, periodic acid[ndash]Schiff-positive lipopigment in neurons and transmission electron microscopy confirmed a typical curvilinear profile of the storage bodies. We hypothesize that rapid brain atrophy ...
Source: Veterinary Radiology & Ultrasound - February 5, 2010 Category: Veterinary Research Authors: MIDORI GOTO ASAKAWA, EDWARD MACKILLOP, NATASHA J. OLBY, IAN D. ROBERTSON, JOHN M. CULLEN Source Type: journals
The anti-inflammatory effect of paeoniflorin on cerebral infarction induced by ischemia-reperfusion injury in sprague-dawley rats.Email this article to a colleague.
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In conclusion, Paeoniflorin reduced cerebral infarct and neurological deficit in ischemia-reperfusion injured rats, suggesting that paeoniflorin may have a similar effect in humans and might be a suitable treatment for stroke. Paeoniflorin reduced cerebral infarct, at least in part, involves the anti-inflammatory properties.
PMID: 20128044 [PubMed - in process]
Source: The American Journal of Chinese Medicine - February 4, 2010 Category: Complementary Medicine Authors: Tang NY, Liu CH, Hsieh CT, Hsieh CL Tags: Am J Chin Med Source Type: journals
Cerebral Malignancy in Psychiatry: EEG AspectsEmail this article to a colleague.
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Psychiatria clin. 1983;16:340349 (DOI:10.1159/000284163)
Source: Psychopathology - February 4, 2010 Category: Psychiatry & Psychology Source Type: journals
Influence of simvastatin on microthrombosis in the brain after subarachnoid hemorrhage in rats: a preliminary study.Email this article to a colleague.
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In conclusion, simvastatin administration attenuates cerebral vasospasm and alleviates microthrombosis in the late phase of SAH in this prechiasmatic blood injection model.
PMID: 20124328 [PubMed - in process]
Source: Annals of Clinical and Laboratory Science - February 4, 2010 Category: Laboratory Medicine Authors: Wang Z, Chen G, Zhu WW, Bian JY, Shen XO, Zhou D Tags: Ann Clin Lab Sci Source Type: journals
Infarct size and left ventricular function in the PRoximal Embolic Protection in Acute myocardial infarction and Resolution of ST-segment Elevation (PREPARE) trial: ancillary cardiovascular magnetic resonance studyEmail this article to a colleague.
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Conclusions
Primary PCI with combined proximal embolic protection and thrombus aspiration in STEMI patients did not result in significant differences in final infarct size or left ventricular function at follow-up CMR. In addition, there was no difference in the incidence of major adverse cardiac and cerebral events at 6 months.
Trial registration number
ISRCTN71104460.
Source: Heart - February 4, 2010 Category: Cardiology Authors: Haeck, J D, Kuijt, W J, Koch, K T, Bilodeau, L, Henriques, J P, Rohling, W J, Baan, J, Vis, M M, Nijveldt, R, van Geloven, N, Groenink, M, Piek, J J, Tijssen, J G, Krucoff, M W, De Winter, R J Tags: Drugs: cardiovascular system, Interventional cardiology, Acute coronary syndromes, Percutaneous intervention Source Type: journals
Magnesium found to boost learning and memoryEmail this article to a colleague.
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We present these findings in protest of the way in which they were acquired.For more information:
http://www.cell.com/neuron/fulltext/S0896-6273(09)01044-7
http://www.naturalnews.com/magnesium.html
Source: NaturalNews.com - February 4, 2010 Category: Consumer Health Advice Source Type: news
Is ventriculomegaly in idiopathic normal pressure hydrocephalus associated with a transmantle gradient in pulsatile intracranial pressure?Email this article to a colleague.
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Conclusions In this cohort of iNPH patients, we found no evidence of transmantle gradient in pulsatile ICP. The data gave no support to
the hypothesis that pulsatile ICP is higher within the CSF of the cerebral ventricles (ICPIV) than within the subdural (ICPSD) compartment or the brain parenchyma (ICPPAR) in iNPH patients.
Content Type Journal ArticleCategory Clinical ArticleDOI 10.1007/s00701-010-0605-xAuthors
Per Kristian Eide, Oslo University Hospital Department of Neurosurgery, Division of Clinical Neuroscience Rikshospitalet HF 0027 Oslo NorwayTerje Sæhle, Oslo University Hospital Department of ...
Source: Acta Neurochirurgica - February 4, 2010 Category: Neurology Tags: Acta Neurochirurgica Source Type: journals
Multiple Coaxial Catheter System for Reliable Access in Interventional Stroke TherapyEmail this article to a colleague.
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In conclusion,
building up a triple or quadruple coaxial system proved to be safe and efficient in our experience for the mechanical thrombectomy
treatment of acute ischemic stroke.
Content Type Journal ArticleCategory Technical NoteDOI 10.1007/s00270-010-9815-0Authors
Zsolt Kulcsár, Geneva University Hospital Neurointerventional Division, Department of Clinical Neurosciences Geneva SwitzerlandHasan Yilmaz, Geneva University Hospital Neurointerventional Division, Department of Clinical Neurosciences Geneva SwitzerlandChristophe Bonvin, Geneva University Hospital Neurology Division, Department of Clinical Neuroscien...
Source: CardioVascular and Interventional Radiology - February 4, 2010 Category: Radiology Tags: CardioVascular and Interventional Radiology Source Type: journals
Cerebral venous sinus thrombosis in a patient with type 1 diabetes in the absence of ketoacidosisEmail this article to a colleague.
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We report a case of CVST in a patient with type 1 diabetes but without DKA, in whom we speculate that chronic poor glycaemic control was a contributory factor. Copyright © 2010 John Wiley & Sons.
Source: Practical Diabetes International - February 4, 2010 Category: Endocrinology Authors: AA Hosseini, RS Manjunatha, A Jacob, M El-Lahawi, V Baskar Tags: Case Reports Source Type: journals
Case report: Hip septic arthritis and abcess after diagnostic coronary angiography.Email this article to a colleague.
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Coronary angiography is an invasive procedure which can have some complications. Septic arthritis and abscess after coronary angiography are extremely rare. In this case, a 49-year-old-man presented to our hospital with non-ST-segment elevation myocardial infarction. After coronary angiography, he had right leg weakness, femoral palsy, inguinal pain, but there was no bleeding or hematoma. The cause was right hip septic arthritis and abscess.
PMID: 20133339 [PubMed - as supplied by publisher]
Source: Perfusion - February 4, 2010 Category: Cardiovascular & Thoracic Surgery Authors: Ayhan H, Akar Bayram N, Keles T, Durmaz T, Bozkurt E Tags: Perfusion Source Type: journals
New concepts regarding cerebral vasospasm: glial-centric mechanisms.Email this article to a colleague.
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CONCLUSIONS: The implication for clinical management is discussed supposing glial cell dysfunction is an underlying mechanism responsible for the vascular spasm.
PMID: 20131107 [PubMed - as supplied by publisher]
Source: Canadian Journal of Anaesthesia - February 4, 2010 Category: Anesthesiology Authors: Mutch WA Tags: Can J Anaesth Source Type: journals
Heparin-Induced Thrombocytopenia in Patients with Philadelphia-Negative Myeloproliferative Disorders and Unusual Splanchnic or Cerebral Vein Thrombosis.Email this article to a colleague.
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Conclusions: Ph-MPD patients on heparin warrant careful monitoring and HIT has to be suspected whenever platelet counts drop or a new thrombosis is detectable.
PMID: 20134155 [PubMed - as supplied by publisher]
Source: Acta Haematologica - February 4, 2010 Category: Hematology Authors: Randi ML, Tezza F, Scapin M, Duner E, Scarparo P, Scandellari R, Fabris F Tags: Acta Haematol Source Type: journals
Hyperlipidemia and Reduced White Matter Hyperintensity Volume in Patients With Ischemic Stroke.Email this article to a colleague.
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CONCLUSIONS: Results from 2 independent cohorts demonstrate that AIS patients with a history of hyperlipidemia have less severe WMH at the time of stroke. These data support the hypothesis that hyperlipidemia may play a relatively protective role in cerebral small-vessel disease.
PMID: 20133919 [PubMed - as supplied by publisher]
Source: Stroke - February 4, 2010 Category: Neurology Authors: Jimenez-Conde J, Biffi A, Rahman R, Kanakis A, Butler C, Sonni S, Massasa E, Cloonan L, Gilson A, Capozzo K, Cortellini L, Ois A, Cuadrado-Godia E, Rodriguez-Campello A, Furie KL, Roquer J, Rosand J, Rost NS Tags: Stroke Source Type: journals
Pattern of Response of National Institutes of Health Stroke Scale Components to Early Recanalization in the CLOTBUST Trial.Email this article to a colleague.
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CONCLUSIONS: All neurological functions, impaired because of MCA occlusion, recovered after recanalization, although not to the same extent. The total NIHSS score is more useful than the individual components in detecting MCA recanalization.
PMID: 20133918 [PubMed - as supplied by publisher]
Source: Stroke - February 4, 2010 Category: Neurology Authors: Mikulik R, Dusek L, Hill MD, Fulep E, Grotta JC, Ribo M, Molina C, Alexandrov AV, Tags: Stroke Source Type: journals
Body alignment and postural muscle activity at quiet standing and anteroposterior stability limits in children with spastic diplegic cerebral palsy.Email this article to a colleague.
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Conclusions. Our findings suggest that children with SDCP have difficulty modulating muscle activity while standing and that the quadriceps plays a critical role in maintaining couch posture. In addition, crouch posture may be improved by the training which focuses on control of the dorsal muscles.
PMID: 20131949 [PubMed - as supplied by publisher]
Source: Disability and Rehabilitation - February 4, 2010 Category: Rehabilitation Authors: Tomita H, Fujiwara K, Fukaya Y Tags: Disabil Rehabil Source Type: journals
Do the self-concept and quality of life decrease in CP patients? Focussing on the predictors of self-concept and quality of life.Email this article to a colleague.
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Conclusion. Self-concept and QOL of the CP children were lower than the children without CP. Presence of incontinence, self-concept rating and GMFCS level were important to predict domains of QOL.
PMID: 20131943 [PubMed - as supplied by publisher]
Source: Disability and Rehabilitation - February 4, 2010 Category: Rehabilitation Authors: Soyupek F, Aktepe E, Savas S, Askin A Tags: Disabil Rehabil Source Type: journals
Heparin-Induced Thrombocytopenia in Patients with Philadelphia-Negative Myeloproliferative Disorders and Unusual Splanchnic or Cerebral Vein ThrombosisEmail this article to a colleague.
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Acta Haematol 2010;123:140145 (DOI:10.1159/000280466)
Source: Karger Publishers - February 3, 2010 Category: Cancer & Oncology Source Type: journals
Rapid and sensitive assessment of the IDH1 and IDH2 mutation status in cerebral gliomas based on DNA pyrosequencingEmail this article to a colleague.
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Abstract Diffusely infiltrating cerebral gliomas frequently carry point mutations in codon 132 of the isocitrate dehydrogenase 1 (IDH1) gene or in codon 172 of the IDH2 gene, which are both clinically important as diagnostic and prognostic markers. Here, we report on a method that allows for
the rapid detection of IDH1 and IDH2 mutations based on pyrosequencing. The method is applicable to routinely processed tissue specimens and provides quantitative
mutation data within less than one working day. Due to its high sensitivity, the technique may also be used for the diagnostic
assessment of IDH1 or IDH2 mutati...
Source: Acta Neuropathologica - February 3, 2010 Category: Neurology Tags: Acta Neuropathologica Source Type: journals
Long-term outcomes of triangle tilt surgery for obstetric brachial plexus injuryEmail this article to a colleague.
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Conclusion The triangle tilt procedure, which addresses scapular and glenohumeral joint abnormalities characteristic of Erb’s palsy,
improves shoulder functional movements and anatomical structure in patients over the long-term.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00383-010-2550-4Authors
Rahul K. Nath, Texas Nerve and Paralysis Institute Houston USAXiaomei Liu, Texas Nerve and Paralysis Institute Houston USASonya E. Melcher, Texas Nerve and Paralysis Institute Houston USAJilao Fan, Texas Nerve and Paralysis Institute Houston USA
Journal Pediatric Surgery Internati...
Source: Pediatric Surgery International - February 3, 2010 Category: Surgery Tags: Pediatric Surgery International Source Type: journals
Disulfiram, an Option for the Treatment of Pathological Gambling?Email this article to a colleague.
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Conclusions: Although uncontrolled case observations should be interpreted with caution, disulfiram deserves further investigation in pathological gambling.
Source: Alcohol and Alcoholism - February 3, 2010 Category: Addiction Authors: Mutschler, J., Buhler, M., Grosshans, M., Diehl, A., Mann, K., Kiefer, F. Tags: Case Report Source Type: journals
Anti-spasticity medications need further researchEmail this article to a colleague.
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Only a few anti-spasticity medications used for children with cerebral palsy are backed by sufficient research to justify their use, according to a new review.
Source: ScienceDaily Headlines - February 3, 2010 Category: Science Source Type: news
Implications of astrocytes in neurovascular couplingEmail this article to a colleague.
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Abstract Normal brain function requires continuous supply of oxygen and glucose in a strict manner. The close spatial and temporal
relationship between neural activity and cerebral blood flow (CBF) is termed as neurovascular coupling, which is dependent
or not dependent on astrocytes. The increase in flow evoked by brain activity is mediated by the concerted action of multiple
mediators that originate from different cells and act at different levels of the cerebral vasculature. More studies are needed
for further understanding the precise mechanisms underlying neurovascular coupling, especially the implicati...
Source: Frontiers of Medicine in China - February 3, 2010 Category: Journals (General) Tags: Frontiers of Medicine in China Source Type: journals
Bell's palsy: Facial paralysis is usually temporaryEmail this article to a colleague.
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Bell's palsy — Comprehensive overview covers causes, treatment of this usually temporary facial paralysis.
Source: MayoClinic.com Full Feed - February 3, 2010 Category: Consumer Health News Source Type: news
Interictal cerebral blood flow abnormality in cryptogenic West syndromeEmail this article to a colleague.
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Discussion: Broad cerebral hypoperfusion with posterior predominance involving the hippocampus and lenticular nucleus implies that even cryptogenic West syndrome has a widespread cerebral dysfunction at least transiently, which would correspond to clinical manifestations of hypsarrhythmia and epileptic spasms. Hippocampal hypoperfusion suggests the dysfunction of hippocampal circuitry in the brain adrenal axis, and may contribute to subsequent cognitive impairment of cryptogenic West syndrome.
Source: Epilepsia - February 3, 2010 Category: Neurology Authors: Shin-ichiro Hamano, Norimichi Higurashi, Reiko Koichihara, Tomotaka Oritsu, Kenjiro Kikuchi, Satoshi Yoshinari, Manabu Tanaka, Motoyuki Minamitani Source Type: journals
Outcomes of static and dynamic facial nerve repair in head and neck cancerEmail this article to a colleague.
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Determine outcomes associated with nerve grafting versus static repair following facial nerve resection.Retrospective chart review.Charts from 105 patients who underwent facial nerve reconstruction between January 1999 and January 2009 were reviewed. The majority had parotid malignancy (78.1%), most commonly squamous cell carcinoma (50.5%). Patients underwent static (n = 72) or dynamic (n = 33) reconstruction with nerve grafting. Facial nerve function was measured using the House-Brackmann (H-B) scale.Patients receiving static reconstruction were on average 10.3 years older (P = .002). Mean overall survival for tumor cases...
Source: The Laryngoscope - February 3, 2010 Category: ENT & OMF Authors: Tim A. Iseli, Gregory Harris, Nichole R. Dean, Claire E. Iseli, Eben L. Rosenthal Source Type: journals
Clinical and dual-tasking aspects in frequent and infrequent fallers with progressive supranuclear palsyEmail this article to a colleague.
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Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease with no sufficient therapeutic options to date. Falls are the most devastating feature. The causes of these falls are not well understood. To test the impact of PSP-associated motor and cognitive features on falls, 26 PSP patients were prospectively recruited and divided into frequent fallers (> one fall/month, 18 patients) and infrequent fallers ([le] one fall/month, 8 patients). Further parameters were assessed by clinical investigation and biomechanical gait and balance analysis with and without dual-task paradigms. Physical activity was measured t...
Source: Movement Disorders - February 3, 2010 Category: Neurology Authors: Ulrich Lindemann, Simone Nicolai, Denis Beische, Clemens Becker, Karin Srulijes, Elisabeth Dietzel, Sarah Bauer, Daniela Berg, Walter Maetzler Source Type: journals
Ictal hypoventilation contributes to cardiac arrhythmia and SUDEP: Report on two deaths in video-EEG–monitored patientsEmail this article to a colleague.
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We report two cases of SUDEP in patients with intractable temporal lobe epilepsy undergoing video-EEG (electroencephalography) telemetry at two centers. Both had secondarily generalized convulsions. EEG, electrocardiography (ECG), and respiratory changes in these two patients are reported herein. Ictal/postictal hypoventilation may contribute to SUDEP with the resulting hypoxemia and acidosis leading to failure of recovery of cortical function and eventual cardiac failure.
Source: Epilepsia - February 3, 2010 Category: Neurology Authors: Lisa M. Bateman, Mark Spitz, Masud Seyal Source Type: journals
Can we predict adverse neonatal outcome in late preterm or term fetal growth restriction?Email this article to a colleague.
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CONCLUSION: : In late preterm or term FGR, GA at delivery is the most important predictor of adverse neonatal outcome. At >37.5 weeks, delivery may be the best option to minimize adverse outcome in all FGR cases. At 34-37 weeks, a score based on GA at delivery, UA PI centile, and AC centile optimally predicts adverse neonatal outcome. Copyright (c) 2010 ISUOG. Published by John Wiley & Sons, Ltd.
PMID: 20131337 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - February 3, 2010 Category: Radiology Authors: Vergani P, Roncaglia N, Ghidini A, Crippa I, Cameroni I, Orsenigo F, Pezzullo J Tags: Ultrasound Obstet Gynecol Source Type: journals
Inflammatory mechanisms in ischemic stroke: role of inflammatory cells.Email this article to a colleague.
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Inflammation plays an important role in the pathogenesis of ischemic stroke and other forms of ischemic brain injury. Experimentally and clinically, the brain responds to ischemic injury with an acute and prolonged inflammatory process, characterized by rapid activation of resident cells (mainly microglia), production of proinflammatory mediators, and infiltration of various types of inflammatory cells (including neutrophils, different subtypes of T cells, monocyte/macrophages, and other cells) into the ischemic brain tissue. These cellular events collaboratively contribute to ischemic brain injury. Despite intense inv...
Source: Journal of Leukocyte Biology - February 3, 2010 Category: Hematology Authors: Jin R, Yang G, Li G Tags: J Leukoc Biol Source Type: journals
Freud's Friends and Enemies One Hundred Years Later, Part 2Email this article to a colleague.
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Can You Find Freud in This Photo?Preamble: In 1909 Sigmund Freud visited the United States for the first and only time. He did so at the invitation of G. Stanley Hall, the president of Clark University, in connection with the 20th anniversary celebration of the founding of America's original graduate student only research institution. Speaking in German to a who's who of psychologists and other social scientists (many of whom would have been multilingual in those days) Freud delivered a series of now famous lectures on psychoanalysis. One hundred years later, on October 3, 2009, Clark University commemorated what is ...
Source: Psychology Today Personality Center - February 2, 2010 Category: Psychiatry & Psychology Authors: Richard Shweder Tags: Personality Philosophy Psychiatry evolutionary psychology Freud healing poststructuralism psychoanalysis religion Source Type: consumer
Anti-apoptotic Actions of PPAR-γ Against Ischemic StrokeEmail this article to a colleague.
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Abstract Stroke is a leading cause of adult disability and mortality. Diabetes is a major risk factor for stroke. Patients with diabetes
have a higher incidence of stroke and a poorer prognosis after stroke. Peroxisome proliferator-activated receptor gamma (PPAR-γ)
is a ligand-modulated transcriptional factor and a therapeutic target for treating type II diabetes. It is well-documented
that activation of PPAR-γ can also attenuate postischemic inflammation and damage. In this review, we focus on the newly revealed
anti-apoptotic actions of PPAR-γ against cerebral ischemia. PPAR-γ, by increasing superoxide...
Source: Molecular Neurobiology - February 2, 2010 Category: Neurology Tags: Molecular Neurobiology Source Type: journals
A novel mutation in LMBRD1 causes the cblF defect of vitamin B12 metabolism in a Turkish patientEmail this article to a colleague.
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Abstract In the cblF defect of vitamin B12 (cobalamin) metabolism, cobalamin is trapped in lysosomes. Consequently, cobalamin coenzyme synthesis is blocked, and cofactors
for methionine synthase and methylmalonyl-coenzyme A (CoA) mutase are deficient. We recently identified LMBRD1 as the causative gene located on chromosome 6q13 and showed that 18 out of 24 alleles in unrelated patients carried the deletion
c.1056delG (p.L352fsX18) (Rutsch et al. (Nat Genet 41:234–239, 2009). LMBRD1 encodes the lysosomal membrane protein LMBD1, which presumably facilitates lysosomal cobalamin export. Our patient is the
seco...
Source: Journal of Inherited Metabolic Disease - February 2, 2010 Category: Internal Medicine Tags: Journal of Inherited Metabolic Disease Source Type: journals
Morphometric analysis of the influence of selenium over vasospastic femoral artery in ratsEmail this article to a colleague.
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Conclusion According to the results of our study, selenium morphometrically prevents the development of peripheral vasospasms.
Content Type Journal ArticleCategory Experimental researchDOI 10.1007/s00701-010-0599-4Authors
Ömür Günaldı, Neurosurgery Clinic Bakırköy Dr. Sadi Konuk Research and Training Hospital Istanbul TurkeyBekir Tuğcu, 2nd Neurosurgery Clinic Bakırköy Research and Training Hospital for Neurology, Neurosurgery and Psychiatry Istanbul TurkeyBarış Çöllüoğlu, Neurosurgery Clinic Muş State Hospital Muş TurkeyDoğan G. Güçlü, Neurosurgery Clinic Bakırköy Dr. Sadi Konuk ...
Source: Acta Neurochirurgica - February 2, 2010 Category: Neurology Tags: Acta Neurochirurgica Source Type: journals
Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel diseaseEmail this article to a colleague.
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Cerebral ischemic small vessel disease (SVD) is the leading cause of vascular dementia and a major contributor to stroke in humans. Dominant mutations in NOTCH3 cause cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a genetic archetype of cerebral ischemic SVD. Progress toward understanding the pathogenesis of this disease and developing effective therapies has been hampered by the lack of a good animal model. Here, we report the development of a mouse model for CADASIL via the introduction of a CADASIL-causing Notch3 point mutation into a large P1-derived artificial chr...
Source: Journal of Clinical Investigation - February 2, 2010 Category: Biomedical Science Authors: Anne Joutel, Marie Monet-Leprêtre, Claudia Gosele, Céline Baron-Menguy, Annette Hammes, Sabine Schmidt, Barbara Lemaire-Carrette, Valérie Domenga, Andreas Schedl, Pierre Lacombe, Norbert Hubner Source Type: journals
Current management of clubfoot (congenital talipes equinovarus)Email this article to a colleague.
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Source: BMJ Online First - February 2, 2010 Category: Journals (General) Authors: Bridgens, J., Kiely, N. Tags: cerebral palsy, Child health, Radiology, Degenerative joint disease, Musculoskeletal syndromes, Clinical diagnostic tests, Radiology (diagnostics), Internet CLINICAL REVIEW Source Type: journals
Non-Traditional Therapy For Kids With Cerebral Palsy Shows EffectiveEmail this article to a colleague.
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On average, a child is diagnosed with Cerebral Palsy every hour of every day in the United States. It's a disease that can affect everything from a child's vision to their ability to walk. Therapy for these kids is tough and frustrating as this is a chronic health condition. A new approach to their standard course of therapy may help them make sizable strides in fighting the disease one step at a time...
Source: Health News from Medical News Today - February 2, 2010 Category: Consumer Health News Tags: Neurology / Neuroscience Source Type: news
