Chemotherapy
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Podcast: Heart attack symptoms in women — Are they different?
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A Mayo Clinic cardiologist explains the differences between heart attack symptoms in women and men.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - November 21, 2009 Category: Consumer Health News Source Type: news
Treatment outcome in patients undergoing surgery for carcinoma larynx and hypopharynx - a follow-up study.Email this article to a colleague.
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Conclusions: Compared with larynx cancers salvage rates are poorer for hypopharyngeal cancers and the role of primary surgery seems to be significantly higher and more decisive in overall survival (OS). Hypopharyngeal cancers therefore warrant a closer follow-up after an organ preservation protocol, to detect recurrence at the earliest stage and plan for an effective salvage surgery. Objective: To evaluate the survival and morbidity of patients treated by surgery for carcinoma of the larynx and hypopharynx according to site. Patients and methods: All patients who had undergone laryngectomy at the Division of Surgical Oncol...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Varghese BT, Sebastian P, Mathew A Tags: Acta Otolaryngol Source Type: journals
Children's Hearing Loss From Cisplatin Chemotherapy Associated With Gene VariantsEmail this article to a colleague.
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Recognizing genetic markers for cisplatin ototoxicity will improve children's treatment outcomes. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 20, 2009 Category: Consumer Health News Tags: Hematology-Oncology Source Type: news
Genasense Given as High-Dose IV Infusion with Chemotherapy Shows Promising Activity in Advanced MelanomaEmail this article to a colleague.
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Data Presented at International Melanoma Conference in
Berlin
Results Follow Decision by Company to Continue Phase 3
AGENDA Trial for Overall Survival
BERKELEY HEIGHTS, N.J.--(BUSINESS WIRE)--Nov 20, 2009 - Genta
Incorporated (OTCBB:... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - November 20, 2009 Category: Pharmaceuticals Source Type: clinical trials
Prolonged neutropenia after irinotecan-based chemotherapy in a child with polymorphisms of UGT1A1 and SLCO1B1Email this article to a colleague.
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We report an 11-year-old female with severe and prolonged neutropenia after irinotecan-based chemotherapy. The patient’s genotyping revealed polymorphisms in both UGT1A1 and SLCO1B1. To our knowledge, this is the first case report of combined genotyping of both UGT1A1 and SLCO1B1 in a child with severe irinotecan toxicity. (Source: Archives of Disease in Childhood)
Source: Archives of Disease in Childhood - November 20, 2009 Category: Pediatrics Authors: Sakaguchi, S, Garcia-Bournissen, F, Kim, R, Schwarz, U I, Nathan, P C, Ito, S Tags: Oncology Drug therapy Source Type: journals
European medical advisory committee does not recommend approval of Avastin for deadly form of brain cancerEmail this article to a colleague.
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Roche announced today that the Committee for Medicinal Products for Human Use (CHMP), which is responsible for conducting the initial assessment of medicinal products that have been filed for marketing authorisation in Europe, has issued a negative opinion relating to the approval of Avastin (bevacizumab) alone or in combination with irinotecan chemotherapy for the treatment of relapsed or progressive glioblastoma (GBM), the most aggressive type of primary malignant brain cancer. (Source: Roche Investor Update)
Source: Roche Investor Update - November 20, 2009 Category: Pharmaceuticals Source Type: organizations
Intraspinal primitive neuroectodermal tumors: Report of four cases and review of the literatureEmail this article to a colleague.
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Chen Jingyu, Song Jinning, Meng Hui, Feng HuaNeurology India 2009 57(5):661-668Intraspinal primitive neuroectodermal tumors (PNETs) are extremely rare and are aggressive with poor outcomes. Till date only 41 cases of intraspinal PNET have been reported. Here we report four new cases. Total excision of the tumor was done in three patients and partial excision in one patient. The unusual clinical features were vertebral metasis in one patient and short history of symptoms for four dasy. All had surgical excision, total excision in three patients and gross partial excision in one patient. Three patients were treated with cran...
Source: Neurology India - November 20, 2009 Category: Neurology Authors: Chen Jingyu, Song Jinning, Meng Hui, Feng Hua Source Type: journals
European medical advisory committee does not recommend approval of Avastin for deadly form of brain cancerEmail this article to a colleague.
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Roche announced today that the Committee for Medicinal Products for Human Use (CHMP), which is responsible for conducting the initial assessment of medicinal products that have been filed for marketing authorisation in Europe, has issued a negative opinion relating to the approval of Avastin (bevacizumab) alone or in combination with irinotecan chemotherapy for the treatment of relapsed or progressive glioblastoma (GBM), the most aggressive type of primary malignant brain cancer. (Source: Roche Media News)
Source: Roche Media News - November 20, 2009 Category: Pharmaceuticals Source Type: organizations
'Chemofog' Takes Toll On Cancer Patients, AustraliaEmail this article to a colleague.
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A condition that affects the memory and concentration of cancer patients undergoing chemotherapy is sustained in a subgroup of patients, compromising their ability to function and long-term quality of life, according to research presented on wednesday at a major cancer conference. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 20, 2009 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news
'Chemofog' Takes Toll On Cancer Patients, AustraliaEmail this article to a colleague.
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A condition that affects the memory and concentration of cancer patients undergoing chemotherapy is sustained in a subgroup of patients, compromising their ability to function and long-term quality of life, according to research presented on wednesday at a major cancer conference. (Source: Cancer / Oncology News From Medical News Today)
Source: Cancer / Oncology News From Medical News Today - November 20, 2009 Category: Cancer & Oncology Tags: Cancer / Oncology Source Type: news
New Toxicity Testing Approach Could Make Chemo Drugs SaferEmail this article to a colleague.
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For cancer patients on chemotherapy, the "cure" can be as deadly as the disease itself. Adverse drug reactions are one of the leading causes of death among patients receiving cancer treatment. Jackson Laboratory Professor Gary Churchill wants to change that. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 20, 2009 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news
New Toxicity Testing Approach Could Make Chemo Drugs SaferEmail this article to a colleague.
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For cancer patients on chemotherapy, the "cure" can be as deadly as the disease itself. Adverse drug reactions are one of the leading causes of death among patients receiving cancer treatment. Jackson Laboratory Professor Gary Churchill wants to change that. With a new two-year, $1 million grant from the National Cancer Institute, Churchill is launching a radical new approach to testing three chemotherapeutic drugs for potential toxic effects. (Source: Cancer / Oncology News From Medical News Today)
Source: Cancer / Oncology News From Medical News Today - November 20, 2009 Category: Cancer & Oncology Tags: Cancer / Oncology Source Type: news
Exelixis Reports Encouraging Phase 1 Data For The PI3K Inhibitor Xl147 (SAR245408) In Combination With Erlotinib At The AACR-NCI-EORTC ConferenceEmail this article to a colleague.
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Exelixis, Inc. (Nasdaq:EXEL) reported interim data from an ongoing phase 1 dose-escalation trial of XL147 (SAR245408) in combination with the EGFR inhibitor erlotinib in patients with advanced solid tumors. XL147 is a selective, orally available small molecule inhibitor of phosphoinositide-3-kinase (PI3K). Activation of the PI3K pathway is a frequent event in human tumors, promoting cell proliferation, survival, and resistance to chemotherapy and radiotherapy. (Source: Cancer / Oncology News From Medical News Today)
Source: Cancer / Oncology News From Medical News Today - November 20, 2009 Category: Cancer & Oncology Tags: Cancer / Oncology Source Type: news
Twenty-one questions about mammograms, cancer screenings and early detectionEmail this article to a colleague.
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(NaturalNews) There's a lot of talk about mammograms and cancer screenings this week. A U.S. government task force altered its recommendations, saying that women under 50 should receive no mammograms at all because the risk of harm far outweighs any promise of saving lives. This, in turn, led to a very vocal backlash from cancer industry promoters and even a few deeply misinformed celebrities like Sheryl Crow who swear by mammograms. (Sheryl Crow has a poor understanding of the effects of ionizing radiation.)Rather than providing new answers, this week's debates on mammograms have actually raised all sorts of new questions...
Source: NaturalNews.com - November 20, 2009 Category: Consumer Health Advice Source Type: news
Bone marrow biopsy and aspiration: What you can expectEmail this article to a colleague.
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Bone marrow biopsy and aspiration — Overview covers definition, risks, results of these procedures.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - November 20, 2009 Category: Consumer Health News Source Type: news
Rheumatoid arthritis diet: Do certain foods reduce symptoms?Email this article to a colleague.
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Certain foods may reduce inflammation associated with rheumatoid arthritis.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - November 20, 2009 Category: Consumer Health News Source Type: news
Cervical mucus method for natural family planningEmail this article to a colleague.
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Cervical mucus method — Overview covers definition, steps for tracking cervical mucus for fertility or contraception.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - November 20, 2009 Category: Consumer Health News Source Type: news
Cold urticariaEmail this article to a colleague.
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— Comprehensive overview covers symptoms, treatment of this allergic skin reaction caused by cold.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - November 20, 2009 Category: Consumer Health News Source Type: news
Exercise-induced asthma: Preventive steps can ease symptomsEmail this article to a colleague.
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Exercise-induced asthma — Comprehensive overview covers treatment, symptoms of this type of asthma.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - November 20, 2009 Category: Consumer Health News Source Type: news
Heart attack: Warning signs of a heart in troubleEmail this article to a colleague.
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Heart attack — Comprehensive overview covers symptoms, causes, treatment of a heart attack.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - November 20, 2009 Category: Consumer Health News Source Type: news
Stressed today, sick tomorrowEmail this article to a colleague.
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Stress makes you more susceptible to illness. Take steps to boost your resistance.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - November 20, 2009 Category: Consumer Health News Source Type: news
Rheumatoid arthritis diet: Do certain foods reduce symptoms?Email this article to a colleague.
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Certain foods may reduce inflammation associated with rheumatoid arthritis.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com - Ask a Specialist)
Source: MayoClinic.com - Ask a Specialist - November 20, 2009 Category: Consumer Health News Source Type: news
Dietary fiber: Essential for a healthy dietEmail this article to a colleague.
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A high-fiber diet offers many health benefits. Here's how to increase your fiber intake.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - November 20, 2009 Category: Consumer Health News Source Type: news
Diagnostic role of whole body bone scintigraphy in atypical skeletal tuberculosis resembling multiple metastases: a case reportEmail this article to a colleague.
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Conclusion:
Scintigraphic bone scanning should be kept in mind when assessing bone pain in patients at a high risk of tuberculosis infection or reactivation. We present this unusual case of multifocal skeletal tuberculosis, and stress the related clinical and diagnostic points with the aim of stimulating a high index of suspicion that could facilitate early diagnosis and appropriate treatment. (Source: BioMed Central)
Source: BioMed Central - November 20, 2009 Category: Journals (General) Authors: Majid AssadiIraj NabipourMohammad EftekhariAbdolali EbrahimiSeyed-Reza AbotorabHooman SalimipourHamid JavadiKatayon VahdatReza GhasemikhahMohsen Saghari Source Type: journals
European CHMP rejects Merck's appeal for reconsideration of negative opinion on license extension of cetuximab for lung cancerEmail this article to a colleague.
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Source: Reuters Health News
Area: News
In July 2009, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency EMEA adopted a negative opinion, recommending the refusal of a license extension for cetuximab (Erbitux®) for the first-line treatment of patients with epidermal growth factor receptor (EGFR)-expressing advanced or metastatic non-small cell lung cancer in combination with platinum-based chemotherapy. The Committee considered that the benefits of the drug in this setting did not outweigh its risks. Following an appeal by Merck for a re-examination of the negative opinion, the CHMP...
Source: NeLM - Oncology - November 20, 2009 Category: Cancer & Oncology Source Type: organizations
[Therapeutic effect of docetaxel combined with oxaliplatin for treatment of recurrent epithelial ovarian cancer.]Email this article to a colleague.
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CONCLUSION: Combination of DTX and OXA produces good therapeutic effect with tolerable toxicity profile for treatment of recurrent epithelial ovarian cancer.
PMID: 19923093 [PubMed - as supplied by publisher] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - November 20, 2009 Category: Universities & Medical Training Authors: Wang J, Han N, Wang HL, Zhang ZM, Fan QX Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: journals
A fatal case of spinal tuberculosis mistaken for metastatic lung cancer: recalling ancient Pott's diseaseEmail this article to a colleague.
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Conclusion:
The rapid diagnosis of spinal TB demands a high index of suspicion and expertise regarding the appropriate diagnostic procedures. Due to the devastating consequences of a missed diagnosis, Mycobacterium tuberculosis should be considered early in every case of spondylitis, intraspinal or paravertebral abscess. The presence of certain alarm signals like a prolonged history of progressive back pain, constitutional symptoms or pulmonary nodules on a chest radiograph, particularly in the upper lobes, may guide the clinical suspicion. (Source: Annals of Clinical Microbiology and Antimicrobials)
Source: Annals of Clinical Microbiology and Antimicrobials - November 20, 2009 Category: Microbiology Authors: Felix RingshausenAndrea TannapfelVolkmar NicolasAndreas WeberHans-Werner DuchnaGerhard Schultze-WerninghausGernot Rohde Source Type: journals
Cytotoxic Effects of Temozolomide and Radiation are Additive- and Schedule-DependentEmail this article to a colleague.
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Conclusions: TMZ is not a radiosensitizing agent but yields additive cytotoxicity in combination with radiation. Our data indicate that TMZ treatment should commence at least 3 days before radiation to achieve maximum benefit. Activation of G2/M checkpoint signaling by TMZ and radiation has a cytoprotective effect that can be overcome by dual inhibition of ATM and ATR. More specific inhibition of checkpoint signaling will be required to increase treatment efficacy without exacerbating toxicity. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - November 19, 2009 Category: Radiology Authors: Anthony J. Chalmers, Elliot M. Ruff, Christine Martindale, Nadia Lovegrove, Susan C. Short Tags: Biology Contributions Source Type: journals
Roles of Radiation Dose and Chemotherapy in the Etiology of Stomach Cancer as a Second MalignancyEmail this article to a colleague.
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Purpose: To evaluate the roles of radiation dose, chemotherapy, and other factors in the etiology of stomach cancer in long-term survivors of testicular cancer or Hodgkin lymphoma.Methods and Materials: We conducted a cohort study in 5,142 survivors of testicular cancer or Hodgkin lymphoma treated in the Netherlands between 1965 and 1995. In a nested case–control study, detailed information on treatment, smoking, gastrointestinal diseases, and family history was collected for 42 patients with stomach cancer and 126 matched controls. For each subject, the mean radiation dose to the stomach was estimated. Relative risks (R...
Source: International Journal of Radiation Oncology * Biology * Physics - November 19, 2009 Category: Radiology Authors: Alexandra W. van den Belt-Dusebout, Berthe M.P. Aleman, Gijs Besseling, Marie L. de Bruin, Michael Hauptmann, Mars B. van 't Veer, Ronald de Wit, Jacques G. Ribot, Evert M. Noordijk, J. Martijn Kerst, Jourik A. Gietema, Flora E. van Leeuwen Tags: Stomach Source Type: journals
Comparative Proteomic Analysis of Human Lung Adenocarcinoma Cisplatin-resistant Cell Strain A549/CDEmail this article to a colleague.
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Conclusion These differentially expressed proteins give some clues to elucidate the mechanism of lung cancer cell resistant of cisplatin, providing the basis of searching for potential target of chemotherapy of lung cancer. (Source: Chinese Journal of Lung Cancer)
Source: Chinese Journal of Lung Cancer - November 19, 2009 Category: Cancer & Oncology Source Type: journals
Down-regulation of GRP78 Enhances Chemotherapy Sensitivity to VP-16 in Lung AdenocarcinomaEmail this article to a colleague.
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Conclusion BAPTA-AM is highly effective in the inhibition of GRP78, down-regulation of GRP78 can significantly increase the sensitivity of adenocacinoma lung cancer to VP-16. All these suggest that inhibition of the expression of GRP78 by chemicals such as BAPTA-AM or anti-sense RNA may be a new therapeutic strategies to lung cancer. (Source: Chinese Journal of Lung Cancer)
Source: Chinese Journal of Lung Cancer - November 19, 2009 Category: Cancer & Oncology Source Type: journals
The Role of Postoperative Radiotherapy on Stage N2 Non-small Cell Lung CancerEmail this article to a colleague.
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Conclusion PORT can improve overall survival for N2 NSCLC, especially the patients with the factors as follows: tumor size > 3 cm and multiple station N2 can benefit from PORT more or less. (Source: Chinese Journal of Lung Cancer)
Source: Chinese Journal of Lung Cancer - November 19, 2009 Category: Cancer & Oncology Source Type: journals
The Clinical Analysis of 21 Patients with Lymphoepithelioma-like Carcinoma after OperationEmail this article to a colleague.
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Conclusion Lymphoepitheliomalike carcinoma of the lung is a very rare and unique subtype of large cell carcinomas of the lung, which has a better prognosis with surgical, chemotherapy and radiotherapy. (Source: Chinese Journal of Lung Cancer)
Source: Chinese Journal of Lung Cancer - November 19, 2009 Category: Cancer & Oncology Source Type: journals
Comparison of the Clinical Effects of Paclitaxel and Paclitaxel plus Oxaliplatin as the Second-line Treatment of Advanced Non-small Cell Lung CancerEmail this article to a colleague.
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Conclusion Singlepaclitaxel administration as the second-lined treatment of advanced NSCLC is tolerable and has the response effect no worse than the combined chemotherapy. (Source: Chinese Journal of Lung Cancer)
Source: Chinese Journal of Lung Cancer - November 19, 2009 Category: Cancer & Oncology Source Type: journals
The Comparison of Clinical Effect of Rh-endostar on Retreated Non-Small Cell Lung Cancer and Colorectal CancerEmail this article to a colleague.
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Conclusion The clinical efficacy of rh-endostatin on retreated colorectal cancer was better than on retreated non-small cell lung cancer, which suggested that it was necessary to perform more clinical observations on the digestive tumors. (Source: Chinese Journal of Lung Cancer)
Source: Chinese Journal of Lung Cancer - November 19, 2009 Category: Cancer & Oncology Source Type: journals
Expression of PTEN, p53 and P-glycoprotein in Non-small cell Lung Cancer and Their Predictive ValuesEmail this article to a colleague.
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Conclusion To some extent, the expression level of PTEN, p53 and P-gp may predict the effect of radiotherapy, chemotherapy and prognosis of NSCLC. (Source: Chinese Journal of Lung Cancer)
Source: Chinese Journal of Lung Cancer - November 19, 2009 Category: Cancer & Oncology Source Type: journals
Persistent non-neoplastic gammadelta-T cells in cerebrospinal fluid of a patient with hepatosplenic (gammadelta) T cell lymphoma: a case report with 6 years of flow cytometry follow-up.Email this article to a colleague.
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We describe a case of a 31-year old man diagnosed with a gammadelta HSTCL in 2003, successfully treated with chemotherapy and allogeneic stem cell transplantation, and followed from 2003 to present. Four-color flow cytometry (FC) was performed on a BD FACSCalibur and data analyzed with CellQuest Pro and FCS Express software. For cerebrospinal fluid (CSF), all cells were acquired due to limited material. Cytological correlation was available on all specimens. Molecular studies for T-cell gene rearrangement were non-contributory. By FC, the diagnostic HSTCL immunophenotype was CD3 (+), CD7 (+), CD2 (+), CD5 (-), CD4 (-), CD8...
Source: International Journal of Clinical and Experimental Pathology - November 19, 2009 Category: Pathology Authors: Jiang L, Abati AD, Wilson W, Stetler-Stevenson M, Yuan C Tags: Int J Clin Exp Pathol Source Type: journals
ASCO issues specific recommendations for chemotherapy in stage IV NSCLCEmail this article to a colleague.
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(Source: HemOncToday.com)
Source: HemOncToday.com - November 19, 2009 Category: Cancer & Oncology Source Type: info
Cancer industry desperately needs mammogram screenings to recruit patients and generate repeat businessEmail this article to a colleague.
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(NaturalNews) Any time you threaten to take away repeat customer from the businesses that make up the cancer industry, you're in for a political fight. After the United States Preventive Services Task Force released new recommendations advising against mammograms for women under 50 (and recommending only bi-annual screenings after that), the cancer industry went berserk.Mammograms, you see, are the bread and butter of the for-profit cancer industry. They serve two very important purposes:Purpose #1: RECRUIT patients. Mammograms are a clever tool for recruiting patients into a highly-profitable regimen of chemotherapy drugs...
Source: NaturalNews.com - November 19, 2009 Category: Consumer Health Advice Source Type: news
Breast cancer: Early detection is keyEmail this article to a colleague.
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Breast cancer — Comprehensive overview covers symptoms, causes, diagnosis, treatment of breast cancer in women.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - November 19, 2009 Category: Consumer Health News Source Type: news
C. difficile infection: Serious threat in hospitals and beyondEmail this article to a colleague.
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C. difficile — Comprehensive overview covers symptoms, treatment and causes of Clostridium difficile bacterial infection.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - November 19, 2009 Category: Consumer Health News Source Type: news
Epididymitis: Symptoms, treatments for an inflamed testicleEmail this article to a colleague.
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Epididymitis — Comprehensive overview covers symptoms, treatment of this inflamed testicle condition.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - November 19, 2009 Category: Consumer Health News Source Type: news
Hydrocele: See your doctor to rule out serious causesEmail this article to a colleague.
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Hydrocele — Comprehensive overview covers causes and treatment of this generally harmless scrotal swelling.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - November 19, 2009 Category: Consumer Health News Source Type: news
Narcissistic personality disorder: Overcoming your extreme esteemEmail this article to a colleague.
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Narcissistic personality disorder — Comprehensive overview covers symptoms, risk factors and treatments.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - November 19, 2009 Category: Consumer Health News Source Type: news
Mammogram guidelines: What's changed?Email this article to a colleague.
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Latest mammogram guidelines for breast cancer screening.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com - Ask a Specialist)
Source: MayoClinic.com - Ask a Specialist - November 19, 2009 Category: Consumer Health News Source Type: news
Being grateful: Giving thanks helps with depressionEmail this article to a colleague.
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Being grateful: Reminding yourself of things to be thankful for can lift your mood.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - November 19, 2009 Category: Consumer Health News Source Type: news
Influence of GSTP1 I105V polymorphism on cumulative neuropathy and outcome of FOLFOX-4 treatment in Asian patients with colorectal carcinomaEmail this article to a colleague.
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Glutathione S-transferase P1 (GSTP1) participates in detoxification of potentially genotoxic compounds that may alter the efficacy and toxicity of platinum-based chemotherapy. We analyzed the influence of I105V polymorphism of GSTP1 on clinico-pathological features and outcomes in 166 Chinese patients with metastatic colorectal carcinoma who had been treated with first-line FOLFOX-4. Combined analysis of GSTP1 I105V, ERCC1-118, and XPD-751 polymorphisms was also conducted. The results showed that, in comparison with Caucasian populations, a remarkably lower prevalence of Val105 allele variants was noted (24.7%). Patients w...
Source: Cancer Science - November 19, 2009 Category: Cancer & Oncology Authors: Yen-Chung Chen, Cheng-Hwai Tzeng, Po-Min Chen, Jen-Kou Lin, Tzu-Chen Lin, Wei-Shone Chen, Jeng-Kae Jiang, Huann-Sheng Wang, Wei-Shu Wang Source Type: journals
Chemotherapy intensity and toxicity among black and white women with advanced and recurrent endometrial cancerEmail this article to a colleague.
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The purpose of this study was to confirm whether black and white women with endometrial cancer are equally tolerant of chemotherapy and identify factors that impact survival.A retrospective review of 169 black women and 982 white women with the International Federation of Gynecologists and Obstetricians stage III, stage IV, or recurrent endometrial carcinoma was performed. All patients received doxorubicin combined with cisplatin. Chemotherapy parameters that were reviewed included relative dose, relative time, and relative dose intensity. Treatment cycles [ge]7 were defined as treatment completion.Although black patients ...
Source: Cancer - November 19, 2009 Category: Cancer & Oncology Authors: John H. Farley, Chunqiao Tian, G. Scott Rose, Carol L. Brown, Michael Birrer, John I. Risinger, J. Tate Thigpen, Gini F. Fleming, Holly H. Gallion, G. Larry Maxwell Source Type: journals
Early Response to Neo-adjuvant Chemotherapy in Carcinoma of the Breast Predicts Both Successful Breast-Conserving Surgery and Decreased Risk of Ipsilateral Breast Tumor RecurrenceEmail this article to a colleague.
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In conclusion, the early response to neo-adjuvant chemotherapy may be a useful predictor of both selection of surgical method and IBTR risk. (Source: The Breast Journal)
Source: The Breast Journal - November 19, 2009 Category: Cancer & Oncology Authors: Makoto Ishitobi, Yoshifumi Komoike, Kazuyoshi Motomura, Hiroki Koyama, Hideo Inaji Source Type: journals
