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FDA Approves New Drug Treatment For Long-Term Pain Relief After Shingles AttacksEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The Food and Drug Administration (FDA) has approved the approval of Qutenza (capsaicin) 8% patch, a medicated skin patch that relieves the pain of post-herpetic neuralgia (PHN), a serious complication that can occur after a bout with shingles. Shingles is an outbreak of rash or blisters on the skin that is caused by the same virus that causes chickenpox - the varicella-zoster virus. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 18, 2009 Category: Consumer Health News Tags: Pain / Anesthetics Source Type: news

FDA Approves New Drug Treatment For Long-Term Pain Relief After Shingles AttacksEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The Food and Drug Administration (FDA) has approved the approval of Qutenza (capsaicin) 8% patch, a medicated skin patch that relieves the pain of post-herpetic neuralgia (PHN), a serious complication that can occur after a bout with shingles. Shingles is an outbreak of rash or blisters on the skin that is caused by the same virus that causes chickenpox - the varicella-zoster virus. (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - November 18, 2009 Category: Anesthesiology Tags: Pain / Anesthetics Source Type: news

SPD 707: Chickenpox exanthema in a child with egg allergy: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - October 31, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Halloween SafetyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Halloween is always a fun holiday for kids. I still remember the year that I had to miss Halloween because I was sick with chickenpox, but hopefully too many kids don't miss out on the fun because of swine flu fears. Of course, kids who are actually sick with swine flu should stay home on Halloween so that they don't get other kids sick. Most others should be able to enjoy Halloween and trick-or-treating though. Keep these Halloween safety tips in mind, including that your kids: wear a safe costume go trick-or-treating with supervision in safe neighborhoods only eat Halloween candy that has been inspected by an adult to ...
Source: About.com Pediatrics - October 29, 2009 Category: Pediatrics Source Type: consumer

Do I Have Shingles?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Each year more than one million people in the U.S. suffer an outbreak of shingles, a blistering rash caused by the same virus that causes chickenpox. A viral infection that is characterized by tingling, itching, and fluid-filled blisters, shingles is common among people living with HIV. Needless to say, shingles symptoms are uncomfortable and can be horribly painful. What's more, shingles symptoms can mimic other conditions, from a drug rash to poison ivy. So are you having shingles symptoms? There are a few ways to tell, but first let me explain exactly what shingles is and who's at risk.More About Opportunistic Infection...
Source: About AIDS / HIV - October 25, 2009 Category: Consumer Health Advice Source Type: consumer

Shingles Raises Risk Of Stroke By 30 Percent Or More In Adults, Study FindsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Adults who develop shingles are about 30 percent more likely to have a stroke within a year than adults who don't have shingles. When the shingles infection involves the skin around the eye and the eye itself, the risk of stroke may increase more than four-fold. Shingles is a painful skin rash caused by the same virus that causes chickenpox. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 9, 2009 Category: Science Source Type: news

The Pain and Itching of ShinglesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Each year more than one million people in the U.S. suffer an outbreak of shingles, a blistering rash caused by the same virus that causes chickenpox. A viral infection that... (Source: About AIDS / HIV)
Source: About AIDS / HIV - October 7, 2009 Category: Consumer Health Advice Source Type: consumer

Cases of chickenpox lowEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
LEVELS of chickenpox in the Lothians have remained low, despite the return to school and nursery of thousands of children. (Source: Scotsman.com News - Health)
Source: Scotsman.com News - Health - October 2, 2009 Category: Consumer Health News Source Type: news

Transmission of varicella vaccine virus, Japan.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report secondary transmission of the vOka strain from an immunocompetent girl with a history of varicella vaccination to her healthy susceptible brother. PMID: 19861086 [PubMed - in process] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - October 1, 2009 Category: Infectious Diseases Authors: Otsuka T, Gomi Y, Inoue N, Uchiyama M Tags: Emerg Infect Dis Source Type: journals

Pox rates remain lowEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ONLY seven cases of chickenpox were reported locally last week, despite the schools now being back. (Source: Scotsman.com News - Health)
Source: Scotsman.com News - Health - September 16, 2009 Category: Consumer Health News Source Type: news

Dermatological conditions presenting at an emergency department in Singapore.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The recognition and management of the common conditions should be core modules in the training of doctors and nurses. PMID: 19787176 [PubMed - in process] (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - August 31, 2009 Category: Journals (General) Authors: Wang E, Lim BL, Than KY Tags: Singapore Med J Source Type: journals

Varicella zoster virus: review of its managementEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
J Oral Pathol Med (2009) Varicella zoster virus (VZV) is one of eight herpes viruses known to infect humans. Primary infection causes varicella (chickenpox), after which virus becomes latent. Years later, VZV reactivates and causes a wide range of neurological diseases. The aim of the present report was to critically examine the published literature to evaluate advantages and limitations of therapy of VZV infection in both immunocompetent and immunocompromised patients. Aciclovir (ACV) has been the drug of choice for many years for the treatment of VZV infections. Recently, other antiviral agents have been developed to ove...
Source: Journal of Oral Pathology and Medicine - August 17, 2009 Category: Pathology Authors: M. B. Mustafa, P. G. Arduino, S. R. Porter Source Type: journals

Fully Vaccinated Kids Still Get Chickenpox During OutbreakEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
During an outbreak of varicella in an elementary school in Arkansas, students who were vaccinated once or twice still came down with the illness, though their symptoms were mild. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 13, 2009 Category: Consumer Health News Tags: Infectious Diseases Source Type: news

[Review] Varicella zoster virus vasculopathies: diverse clinical manifestations, laboratory features, pathogenesis, and treatmentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Vasculopathies caused by varicella zoster virus (VZV) are indicative of a productive virus infection in cerebral arteries after either reactivation of VZV (shingles) or primary infection (chickenpox). VZV vasculopathy can cause ischaemic infarction of the brain and spinal cord, as well as aneurysm, subarachnoid and cerebral haemorrhage, carotid dissection, and, rarely, peripheral arterial disease. VZV vasculopathy in immunocompetent or immunocompromised individuals can be unifocal or multifocal with deep-seated and superficial infarctions. Lesions at the grey–white matter junction on brain imaging are a clue to diagnosis...
Source: Lancet Neurology - July 12, 2009 Category: Neurology Authors: Don Gilden, Randall J Cohrs, Ravi Mahalingam, Maria A Nagel Tags: Review Source Type: journals

20 catch the mumpsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
TWENTY cases of the mumps were among the infections recorded across the Lothians last week. Official figures show there were also 17 instances of chickenpox and 41 bouts of fo (Source: Scotsman.com News - Health)
Source: Scotsman.com News - Health - July 2, 2009 Category: Consumer Health News Source Type: news

Giant basilar artery aneurysm in a child after exposure to chickenpox virus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19412747 [PubMed - indexed for MEDLINE] (Source: Wiener Klinische Wochenschrift)
Source: Wiener Klinische Wochenschrift - June 27, 2009 Category: Journals (General) Authors: Kantarci M, Ogul H, Tan H, Albayram S Tags: Wien Klin Wochenschr Source Type: journals

What Is Shingles? What Causes Shingles?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Shingles is caused by the herpes varicella-zoster (or simply zoster) virus. This virus also causes chickenpox. Most of us get chickenpox during childhood, but after we recover the virus remains inactive (dormant) in our nervous system. Our immune system stops the virus from becoming active. However, later in life it may become reactivated, causing shingles. Shingles is an infection of a nerve and the area of skin around it. According to Medilexicon's (Source: Dermatology News From Medical News Today)
Source: Dermatology News From Medical News Today - June 23, 2009 Category: Dermatology Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Does varicella-zoster virus infection of the peripheral ganglia cause Chronic Fatigue Syndrome?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article posits that infection of the peripheral ganglia causes at least some cases of Chronic Fatigue Syndrome (CFS), with a neurotropic herpesvirus, particularly varicella-zoster virus (VZV), as the most likely cause of the infection. Virtually all CFS symptoms could be produced by an infection of the peripheral ganglia, with infection of the autonomic ganglia causing fatigue, postural hypotension, and sleep disturbances, and infection of the sensory ganglia causing sensory symptoms such as chronic pain. Furthermore, infections of the peripheral ganglia are known to cause long-term nerve dysfunction, which would help...
Source: Medical Hypotheses - June 10, 2009 Category: Biomedical Science Authors: Judith S. Shapiro Source Type: journals

100 chickenpox cases in LothianEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
MORE than 100 cases of chickenpox were reported in the Lothians last week, new figures have shown. Statistics issued by Health Protection Scotland revealed there were 126 ins (Source: Scotsman.com News - Health)
Source: Scotsman.com News - Health - June 5, 2009 Category: Consumer Health News Source Type: news

Chickenpox Related to Lower Risk of MS in ChildhoodEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A paper in the May 15th issue of the American Journal of Epidemiology suggests an association between clinically observed chickenpox and a lower risk of childhood-onset multiple sclerosis. Reuters Health Information (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - May 27, 2009 Category: Infectious Diseases Tags: Pediatrics Source Type: info

Clinically Observed Chickenpox and the Risk of Childhood-onset Multiple SclerosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The authors conducted a population-based case-control study to investigate whether clinically observed chickenpox, linked with a level of intensity for clinical expression, increases the risk of multiple sclerosis (MS) in childhood. The cases were MS patients whose disease onset occurred between 1994 and 2003, before age 16 years, in France. Each case was matched for age, sex, and geographic origin with as many as 12 controls randomly selected from the general population. Information about clinically observed chickenpox in cases and controls before the index date regarding onset of MS was collected with a standardized ques...
Source: American Journal of Epidemiology - April 30, 2009 Category: Epidemiology Authors: Mikaeloff, Y., Caridade, G., Suissa, S., Tardieu, M., on Behalf of the KIDSEP Study Group Tags: RESEARCH-ARTICLE Source Type: journals

Hemorrhagic Pericarditis in a child with primary varicella infection (chickenpox).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a malnourished 5-year-old girl with chicken pox complicated by hemorrhagic pericarditis and deep vein thrombosis leading to fatal pulmonary thromboembolism. Though varicella infection runs a benign self-limiting course, it continues to cause significant morbidity and mortality when associated with complications, particularly in malnourished children. Hence, the importance of vaccination and early recognition of complications is emphasized. PMID: 19332925 [PubMed - in process] (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - April 1, 2009 Category: Pathology Authors: Nandeesh BN, Mahadevan A, Yasha TC, Shankar SK Tags: Indian J Pathol Microbiol Source Type: journals

The basics - Chickenpox in adults and pregnancyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Varicella zoster may require intensive management. By Dr Harry Brown. (Source: HealthcareRepublic Clinical Articles)
Source: HealthcareRepublic Clinical Articles - March 26, 2009 Category: Primary Care Source Type: info

Chickenpox Tied to Autoimmune HepatitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A case report from Saudi Arabia in which a patient with varicella zoster infection went on to develop severe autoimmune hepatitis helps sheds more light on this poorly understood condition. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - March 19, 2009 Category: Gastroenterology Tags: Infectious Diseases Source Type: info

Threshold Parameters For A Model Of Epidemic Spread Among Households And WorkplacesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Directly transmissible diseases (like influenza, SARS, measles, chickenpox, and so on) spread primarily through repeated and more intense contacts occurring among people living in the same household or working together. Mathematical models which explicitly take into account the presence of households have been studied in the last 15 years. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 2, 2009 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Vaccines for post-exposure prophylaxis against varicella (chickenpox) in children and adults; Surgical techniques for uterine incision and uterine closure at the time of caesarean section; Topical treatments for fungal infections of the foot; Interventions for the management of overweight and obese children that include a dietary component.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 19222646 [PubMed - as supplied by publisher] (Source: Journal of Advanced Nursing)
Source: Journal of Advanced Nursing - February 20, 2009 Category: Nursing Tags: J Adv Nurs Source Type: journals

The course and outcome of unilateral intracranial arteriopathy in 79 children with ischaemic strokeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Arteriopathies are the commonest cause of arterial ischaemic stroke (AIS) in children. Repeated vascular imaging in children with AIS demonstrated the existence of a ‘transient cerebral arteriopathy’ (TCA), characterized by lenticulostriate infarction due to non-progressive unilateral arterial disease affecting the supraclinoid internal carotid artery and its proximal branches. To further characterize the course of childhood arteriopathies, and to differentiate TCA from progressive arterial disease, we studied the long-term evolution of unilateral anterior circulation arteriopathy, and explored predictors of st...
Source: Brain - February 10, 2009 Category: Neurology Authors: Braun, K. P. J., Bulder, M. M. M., Chabrier, S., Kirkham, F. J., Uiterwaal, C. S. P., Tardieu, M., Sebire, G. Tags: Original Articles Source Type: journals

Quantitative measurement of Varicella Zoster Virus infection using semi-automated flow cytometry.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we have developed a flow cytometry assay to measure the infectivity of the attenuated vaccine strain (Oka/Merck) of VZV in MRC-5 cells with improved throughput. The assay is performed in 96-well tissue culture microtiter plates and is based on the detection and quantification of infected cells expressing VZV glycoproteins on their surface. Multiple assay parameters have been investigated, including specificity, limit of detection (LOD), limit of quantification (LOQ), range of linear response, signal to noise ratio and precision. This novel assay appears to be in good concordance with the classical plaque ass...
Source: Applied and Environmental Microbiology - February 5, 2009 Category: Microbiology Authors: Gates IV, Zhang Y, Shambaugh C, Bauman MA, Tan C, Bodmer JL Tags: Appl Environ Microbiol Source Type: journals

Chickenpox vaccine not linked to strokes in childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Children who have received the chickenpox vaccine are not at risk of stroke or brain inflammation, according to researched published in the February 2009 issue of Pediatrics. (Source: Modern Medicine Contemporary Pediatrics)
Source: Modern Medicine Contemporary Pediatrics - February 3, 2009 Category: Pediatrics Source Type: info

You're Invited ...to a Chickenpox Party?!Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To avoid another vaccination, some parents are turning to chickenpox parties. (Source: ABC News: Health)
Source: ABC News: Health - February 2, 2009 Category: Consumer Health News Source Type: news

Chickenpox vaccine ‘does not increase stroke risk in children’Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Results of a large US study show no evidence to suggest that the chickenpox vaccine is associated with an increased risk of stroke in children. (Source: MedWire News - Consumer Health)
Source: MedWire News - Consumer Health - January 30, 2009 Category: Consumer Health News Source Type: news

Acute cerebellar ataxia in the Netherlands: A study on the association with vaccinations and varicella zoster infection.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The incidence rates were comparable with other studies. We found no association with MMR, but chickenpox was clearly related to ACA. According to age-specific seroprevalence data the incidence rate of ACA was 5:100,000 VZV infections for children up to 5 years, compared to an ACA-reporting rate of 0.15:100,000 doses VZV-vaccine. Therefore, uptake of VZV-vaccine in the immunization programme will diminish the incidence rate of ACA. PMID: 19186201 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - January 29, 2009 Category: Allergy & Immunology Authors: van der Maas NA, Bondt PE, de Melker H, Kemmeren JM Tags: Vaccine Source Type: journals

Chickenpox vaccine not tied to strokes in kidsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
NEW YORK (Reuters Health) - Unlike chickenpox itself, the vaccine against chickenpox does not increase the risk of stroke or brain inflammation in children, according to a large US study reported in the journal Pediatrics. (Source: Reuters: Health)
Source: Reuters: Health - January 27, 2009 Category: Consumer Health News Tags: healthNews Source Type: news

Performance characteristics of a quantitative, standardised varicella zoster IgG time resolved fluorescence immunoassay (VZV TRFIA) for measuring immunity following natural infection.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Infection by Varicella Zoster virus (VZV) during pregnancy has been associated with adverse foetal development and more severe disease in the mother. Accurate determination of VZV immunity in pregnant women exposed to VZV, with no history of chickenpox, guides therapeutic interventions. The accepted gold standard assay for the determination of immunity/protection against Varicella Zoster virus was for many years the fluorescent antibody to membrane antigen (FAMA) assay which is labour intensive and subjective. A validated alternative is the Merck glycoprotein EIA (Merck Sharp & Dohme Research Laboratories, West Poi...
Source: Journal of Virological Methods - January 6, 2009 Category: Virology Authors: Chris Maple PA, Gray J, Brown K, Brown D Tags: J Virol Methods Source Type: journals

Plan for new jab to eradicate chickenpoxEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
WOMEN and children could be vaccinated against chickenpox under plans being considered by health officials. (Source: Scotsman.com News - Health)
Source: Scotsman.com News - Health - January 4, 2009 Category: Consumer Health News Source Type: news

Chickenpox jab for all children and pregnant womenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Children and pregnant women could be routinely vaccinated against chickenpox. (Source: the Mail online | Health)
Source: the Mail online | Health - January 3, 2009 Category: Consumer Health News Source Type: news

Chickenpox jab for all children and pregnant womenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Children and pregnant women could be routinely vaccinated against chickenpox. (Source: the Mail online | Diet)
Source: the Mail online | Diet - January 3, 2009 Category: Nutrition Source Type: news

Prolonged detection of viral DNA in blood following life-threatening chickenpox in an immunocompromised child.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19109054 [PubMed - as supplied by publisher] (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - December 22, 2008 Category: Virology Authors: Waugh S, Hayden J, Clark J, Saunders D, Taha Y, Taylor C, Valappil M, Bailey S Tags: J Clin Virol Source Type: journals

Varicella in the fetus and newbornEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Summary: Varicella (chickenpox) in pregnancy is unusual because most women of childbearing age are immune. It can, however, cause significant morbidity for the pregnant woman and in rare cases cause congenital varicella syndrome. The incidence of congenital varicella syndrome after maternal varicella during the first two trimesters is (Source: Seminars in Fetal and Neonatal Medicine)
Source: Seminars in Fetal and Neonatal Medicine - December 22, 2008 Category: Perinatology & Neonatology Authors: Candice K. Smith, Ann M. Arvin Source Type: journals

Responding to suspected smallpox cases in the Los Angeles County from 2002 to 2006: identifying areas for education.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Public health investigated 5 suspected smallpox cases in the past 5 years. Two presented initially to EDs. Education differentiating smallpox from chickenpox and collaboration between public health, EDs, and health care providers remains important. The ability to respond rapidly to a potential bioterrorism emergency was tested. PMID: 19041534 [PubMed - in process] (Source: The American Journal of Emergency Medicine)
Source: The American Journal of Emergency Medicine - December 3, 2008 Category: Emergency Medicine Authors: Kim M, Terashita D, Borenstein L, Mascola L Tags: Am J Emerg Med Source Type: journals

Varicella zoster virus vaccine live: Rash and chickenpox in immunosuppressed patients: 13 case reports.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 30 (Source: Reactions Weekly)
Source: Reactions Weekly - November 23, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Varicella zoster virus vaccine live: Rash and chickenpox in immunosuppressed patients: 13 case reportsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - November 23, 2008 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

[Herpes zoster in old adults.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The varicella-zoster virus is an exclusively human herpesvirus, responsible for chickenpox. Its reactivation, after several decades, causes herpes zoster (shingles). Herpes zoster produces a rash, classically metameric, that causes acute pain and complications to elderly patients. The last, most painful, and disabling of these is postherpetic neuralgia. This neuralgia is defined as a painful syndrome lasting for more than 30 days after eruption of the rash. Today's systemic antiviral drugs can reduce the severity of the eruption, limit the pain, and diminish the incidence of postherpetic neuralgia. A recent advance in ...
Source: Presse Medicale - November 21, 2008 Category: Journals (General) Authors: Lang PO, Belmin J, Michel JP Tags: Presse Med Source Type: journals

Pox pops up in LothiansEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CHICKENPOX has re-emerged in the Lothians following an absence of nearly three months. (Source: Scotsman.com News - Health)
Source: Scotsman.com News - Health - November 11, 2008 Category: Consumer Health News Source Type: news

Discordant varicella-zoster virus glycoprotein C expression and localization between cultured cells and human skin vesicles.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this report, we investigated the kinetics of gC expression in more detail and included studies of monolayers inoculated with trypsin dispersed infected cells, the more traditional method of VZV infection. Extensive imaging analyses disclosed that gC was detectable in some inoculum cells, but little gC biosynthesis occurred during the first 48 hpi in the newly infected underlying monolayer. In contrast, during the first 24-48 hpi, expression of VZV gE and gB was easily detectable. Using real-time RT-PCR, we found a delay in accumulation of VZV gC transcripts that paralleled the delay in expression of VZV gC protein. Trea...
Source: Virology - October 25, 2008 Category: Virology Authors: Storlie J, Carpenter JE, Jackson W, Grose C Tags: Virology Source Type: journals

Using Time-Use Data to Parameterize Models for the Spread of Close-Contact Infectious DiseasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Social contact patterns are a critical explanatory factor of the spread of close-contact infectious agents. Both indirect (via observed epidemiologic data) and direct (via diaries that record at-risk events) approaches to the measurement of contacts by age have been proposed in the literature. In this paper, the authors discuss the possibilities offered by time-use surveys to measure contact patterns and to explain observed seroprevalence profiles. The authors first develop a methodology to estimate time-of-exposure matrices, and then they apply it to time-use data for the United States (1987–2003). Finally, the auth...
Source: American Journal of Epidemiology - October 24, 2008 Category: Epidemiology Authors: Zagheni, E., Billari, F. C., Manfredi, P., Melegaro, A., Mossong, J., Edmunds, W. J. Tags: RESEARCH-ARTICLE Source Type: journals

Comparison of the performance of the LIAISON VZV-IgG and VIDAS automated enzyme linked fluorescent immunoassays with reference to a VZV-IgG time-resolved fluorescence immunoassay and implications of choice of cut-off for LIAISON assay.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: By dose-response data and in comparison with TRFIA, LIAISON is more sensitive and specific than VIDAS. PMID: 18823815 [PubMed - as supplied by publisher] (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - September 26, 2008 Category: Virology Authors: Maple PA, Rathod P, Smit E, Gray J, Brown D, Boxall EH Tags: J Clin Virol Source Type: journals

[Varicella pneumonia]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The seroprevalence of chickenpox in countries with temperate climate is very high among young people. Only 4% of the infections occur in adults but the clinical course is usually more severe than in children. In adults, The mortality is approximately 40 times higher and the complication rate 25 times higher than in children. Pneumonia is the most frequent complication in adults and may be extremely severe in immunocompromised patients and in pregnant women. Pneumonia must be promptly treated with intravenous aciclovir. Vaccination is indicated in young seronegative patients with supplemental risk factors for severe com...
Source: Praxis - September 24, 2008 Category: Journals (General) Authors: Meylan P, Vollenweider P, Gianinazzi F, Monti M Tags: Praxis (Bern 1994) Source Type: journals

Perceived Vaccination Status in Ecotourists and Risks of AnthropozoonosesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Anthropozoonotic (human to nonhuman animal) transmission of infectious disease poses a significant threat to wildlife. A large proportion of travelers to tropical regions are not protected against vaccine-preventable illnesses, and a majority of these travelers demonstrate poor recall of actual vaccination status. Here we characterize self-perceived vaccination status among a large sample of ecotourists at the Sepilok Orangutan Rehabilitation Centre, Sabah, Malaysia. Despite their recognized travel itinerary to view endangered animals, tourists at wildlife sanctuaries are not adequately protected ag...
Source: EcoHealth - September 23, 2008 Category: Environmental Health Tags: EcoHealth Source Type: journals

Using Time-Use Data to Parameterize Models for the Spread of Close-Contact Infectious Diseases.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Social contact patterns are a critical explanatory factor of the spread of close-contact infectious agents. Both indirect (via observed epidemiologic data) and direct (via diaries that record at-risk events) approaches to the measurement of contacts by age have been proposed in the literature. In this paper, the authors discuss the possibilities offered by time-use surveys to measure contact patterns and to explain observed seroprevalence profiles. The authors first develop a methodology to estimate time-of-exposure matrices, and then they apply it to time-use data for the United States (1987-2003). Finally, the author...
Source: Am J Epidemiol - September 18, 2008 Category: Epidemiology Authors: Zagheni E, Billari FC, Manfredi P, Melegaro A, Mossong J, Edmunds WJ Tags: Am J Epidemiol Source Type: journals