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Primary Malignant Giant-Cell Tumor of Bone Has High Survival RateEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions We found that malignant and benign GCT have similar epidemiology and that recurrence was higher in MGCT (20 v 9%). Local recurrence for MGCT was not statistically different for excision versus intralesional therapy, but there was little statistical power. Finally, the 16% mortality for patients with MGCT suggests low-grade malignancy. Content Type Journal ArticleCategory Bone and Soft Tissue SarcomasDOI 10.1245/s10434-009-0803-zAuthors Stepan V. Domovitov, Memorial Sloan-Kettering Cancer Center Orthopaedic Surgery Service, Department of Surgery New York USAJohn H. Healey, Memorial Sloan-Ke...
Source: Annals of Surgical Oncology - November 10, 2009 Category: Cancer & Oncology Tags: Annals of Surgical Oncology Source Type: journals

Multiwavelength Laser Treatment of Venous LakesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report our experiences using a multiwavelength laser, which has not been previously described. Thirty-nine VLs in 30 patients were treated. Treatment with 595-nm pulsed-dye laser was conducted at 20 ms and 10 J/cm2, followed by 1,064-nm neodymium-doped yttrium aluminum garnet laser at 20 ms and 70 J/cm2. Complete resolution was observed in 38 lesions (95%). No complications after treatment were noted. One case developed a small scar. Multiwavelentgh laser (595 nm; 1,064 nm) provides a safe, fast, and effective option in the treatment of VLs. The authors have indicated no significant interest with commercial supporters. ...
Source: Dermatologic Surgery - November 3, 2009 Category: Dermatology Authors: MÓNICA RONCERO, JAVIER CAÑUETO, SUSANA BLANCO, PABLO UNAMUNO, PABLO BOIXEDA Source Type: journals

Cooper Surgical, Inc. - Cryosurgical Freezer - Class 2 RecallEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Wallach LL100 Cryosurgical Freezer CO2 Unpinned Yoke System CO2 Model: 900000. (Source: Medical Device Recalls since July 07, 2006)
Source: Medical Device Recalls since July 07, 2006 - October 30, 2009 Category: Medical Equipment Source Type: organizations

Cooper Surgical, Inc. - Cryosurgical Freezer - Class 2 RecallEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Wallach LL100 Cryosurgical Freezer CO2 System Model: 900107. (Source: Medical Device Recalls since July 07, 2006)
Source: Medical Device Recalls since July 07, 2006 - October 30, 2009 Category: Medical Equipment Source Type: organizations

Cooper Surgical, Inc. - Cryosurgical Freezer - Class 2 RecallEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
WA 1000A with Blank Console Model: 900506x. (Source: Medical Device Recalls since July 07, 2006)
Source: Medical Device Recalls since July 07, 2006 - October 30, 2009 Category: Medical Equipment Source Type: organizations

Cooper Surgical, Inc. - Cryosurgical Freezer - Class 2 RecallEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Wallach LL100 Cryosurgical Freezer Short Shaft CO2 System Model: 900034. (Source: Medical Device Recalls since July 07, 2006)
Source: Medical Device Recalls since July 07, 2006 - October 30, 2009 Category: Medical Equipment Source Type: organizations

Cooper Surgical, Inc. - Cryosurgical Freezer - Class 2 RecallEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Wallach LL50x Cryosurgical Freezer CO2 System Model: 900007. (Source: Medical Device Recalls since July 07, 2006)
Source: Medical Device Recalls since July 07, 2006 - October 30, 2009 Category: Medical Equipment Source Type: organizations

Cooper Surgical, Inc. - Cryosurgical Freezer - Class 2 RecallEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Wallach LL50x Cryosurgical Freezer CO2 Unpinned Yoke System Model: 900010. (Source: Medical Device Recalls since July 07, 2006)
Source: Medical Device Recalls since July 07, 2006 - October 30, 2009 Category: Medical Equipment Source Type: organizations

Cooper Surgical, Inc. - Cryosurgical Freezer - Class 2 RecallEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
WA 1000 A/B Console Model: 900516x. (Source: Medical Device Recalls since July 07, 2006)
Source: Medical Device Recalls since July 07, 2006 - October 30, 2009 Category: Medical Equipment Source Type: organizations

Cooper Surgical, Inc. - Cryosurgical Freezer - Class 2 RecallEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Wallach LL100 Cryosurgical Freezer CO2 System Model: 9000002X. (Source: Medical Device Recalls since July 07, 2006)
Source: Medical Device Recalls since July 07, 2006 - October 30, 2009 Category: Medical Equipment Source Type: organizations

Cooper Surgical, Inc. - Cryosurgical Freezer - Class 2 RecallEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Wallach LL100 Cryosurgical Freezer CO2 System Model: 900043. (Source: Medical Device Recalls since July 07, 2006)
Source: Medical Device Recalls since July 07, 2006 - October 30, 2009 Category: Medical Equipment Source Type: organizations

Cooper Surgical, Inc. - Cryosurgical Freezer - Class 2 RecallEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Wallach LL100 Cryosurgical Freezer No Gas Fitting CO2 System Model: 900019x. (Source: Medical Device Recalls since July 07, 2006)
Source: Medical Device Recalls since July 07, 2006 - October 30, 2009 Category: Medical Equipment Source Type: organizations

Cooper Surgical, Inc. - Cryosurgical Freezer - Class 2 RecallEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Wallach LL100 Cryosurgical Freezer No Connector CO2 System Model: 900047. (Source: Medical Device Recalls since July 07, 2006)
Source: Medical Device Recalls since July 07, 2006 - October 30, 2009 Category: Medical Equipment Source Type: organizations

Cooper Surgical, Inc. - Cryosurgical Freezer - Class 2 RecallEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Wallach LL100 Cryosurgical Freezer Atom CO2 System Model: 900036. (Source: Medical Device Recalls since July 07, 2006)
Source: Medical Device Recalls since July 07, 2006 - October 30, 2009 Category: Medical Equipment Source Type: organizations

Cooper Surgical, Inc. - Cryosurgical Freezer - Class 2 RecallEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
WA 4000 Console Model: 900509x. (Source: Medical Device Recalls since July 07, 2006)
Source: Medical Device Recalls since July 07, 2006 - October 30, 2009 Category: Medical Equipment Source Type: organizations

Sexually transmitted papillomavirus infections: epidemiology pathogenesis, clinic, morphology, important differential diagnostic aspects, current diagnostic and treatment optionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The family of human papilloma viruses (HPV) comprises more than 100 genotypes. Approximately 30 of the genotypes are responsible for infections in the human anogenital area. A precisely defined algorithm with the goal of diagnosing and removing HPV for a prolonged or indefinite length of time, as well as to protect the patient from any malignant ransformation, does not currently exist. The identification of HPV strains by PCR or DNA hybridization in lesional tissue provides higher security for the patients. In high-risk patients additional colposcopy, rectoscopy, and rethroscopy/cystoscopy increase the probability of prope...
Source: Anais Brasileiros de Dermatologia - October 23, 2009 Category: Dermatology Source Type: journals

Experimental Cryosurgery Investigations In Vivo.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cryosurgery is the use of freezing temperatures to elicit an ablative response in a targeted tissue. This review provides a global overview of experimentation in vivo which has been the basis of advancement of this widely applied therapeutic option. The cellular and tissue-related events that underlie the mechanisms of destruction, including direct cell injury (cryolysis), vascular stasis, apoptosis and necrosis, are described and are related to the optimal methods of technique of freezing to achieve efficacious therapy. In vivo experiments with major organs, including wound healing, the putative immunological response...
Source: Cryobiology - October 11, 2009 Category: Biology Authors: Gage AA, Baust JM, Baust JG Tags: Cryobiology Source Type: journals

Aneurysmal bone cyst: The role of cryosurgery as local adjuvant treatmentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study is done to assess the outcome of curettage and cryosurgery as a treatment of ABC.We analyzed 80 consecutive cases of ABC treated with curettage and cryosurgery. Patients were followed minimal 24 months after surgery (average 55 months, range 24-122 months) with physical examination and radiographs. Functional outcome was evaluated using the musculoskeletal tumor society score (MSTS).The 80 patients were all treated with curettage and cryosurgery. Additional bone grafting was used in 73 patients, osteosynthesis in 12 and spondylodesis in 1 patient. Four local recurrences were found in this study, a recurrence rat...
Source: Journal of Surgical Oncology - October 9, 2009 Category: Cancer & Oncology Authors: S.P. Peeters, I.C.M. Van der Geest, J.W.J. de Rooy, R.P.H. Veth, H.W.B. Schreuder Source Type: journals

Curettage-Cryosurgery for Scalp, Facial Skin Cancers Expedient and Well ToleratedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No major complications, few minor complications, excellent self-estimated cosmetic result, and few recurrences make curettage-cryosurgery a highly viable treatment alternative for non-melanoma skin cancers on the face and scalp, according to a report in the September British Journal of Dermatology. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 29, 2009 Category: Consumer Health News Tags: Dermatology Source Type: news

Binghamton Research Group Develops New Cancer TreatmentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
After years of innovation and intensive research, a team of Binghamton University (BU) researchers working with Cell Preservation Services, Inc., Owego, NY has broken extraordinary new ground in the recognition of cryosurgery as a primary treatment option for prostate cancer. (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - September 16, 2009 Category: Pharmaceuticals Source Type: news

Fractional Cryosurgery for Skin CancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cryosurgical treatment of facial skin cancers 10 mm or larger in diameter can originate retractile scars that may alter physiognomic features. To treat skin cancers 10 mm or larger in diameter on the face with a cryosurgical method that prevents retractile scars. Also, to clarify the differences between this method and Zacarian's segmental cryosurgery. Fractional cryosurgery is performed in stages. First, the center of the lesion is frozen, reducing its size, then this procedure is repeated as necessary until the tumor diameter is smaller than 10 mm, at which point the standard cryosurgical procedure is performed. Eighty-s...
Source: Dermatologic Surgery - August 31, 2009 Category: Dermatology Authors: JOSE CARLOS ALMEIDA GONÇALVES Source Type: journals

Measurement of the size of intracellular ice crystals in mouse oocytes using a melting point depression method and the influence of intracellular solute concentrations.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we investigated the influence of the concentration of extracellular non-permeable and permeable solutes on the melting points of the intracellular ice in mouse oocytes using cryomicroscopy. The results showed that the melting points of the intracellular ice are always lower than the extracellular ice. Based on this observation and the Gibbs-Thomson relation, we established a physical model to calculate the size of intracellular ice crystals and described its relationship with the concentrations of intracellular permeating solutes and macromolecules. This model predicts that the increased concentration of mac...
Source: Cryobiology - August 30, 2009 Category: Biology Authors: Han X, Critser JK Tags: Cryobiology Source Type: journals

Development and Estimation of a Novel Cryoprobe Utilizing the Peltier Effect for Precise and Safe Cryosurgery.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We have developed a novel cryoprobe for skin cryosurgery utilizing the Peltier effect. The four most important parameters for necrotizing tissue efficiently are the cooling rate, end temperature, hold time and thawing rate. In cryosurgery for small skin diseases such as flecks or early carcinoma, it is also important to control the thickness of the frozen region precisely to prevent necrotizing healthy tissue. To satisfy these exacting conditions, we have developed a novel cryoprobe to which a Peltier module was attached. The cryoprobe makes it possible to control heat transfer to skin surface precisely using a proport...
Source: Cryobiology - August 28, 2009 Category: Biology Authors: Takeda H, Maruyama S, Okajima J, Aiba S, Komiya A Tags: Cryobiology Source Type: journals

Lobomycosis: diagnosis and management of relapsed and multifocal lesionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of lobomycosis in the left leg of a patient that had traveled to the endemic Brazilian Amazon region. After surgical resection of the lesion, there was relapse with local dissemination of the disease and the treatment was successfully performed by oral itraconazole and cryosurgery. (Source: Diagnostic Microbiology and Infectious Disease)
Source: Diagnostic Microbiology and Infectious Disease - August 13, 2009 Category: Microbiology Authors: Fabiana Pirani Carneiro, Lívia Bravo Maia, Mário Augusto P. Moraes, Albino Verçosa de Magalhães, Leonora Maciel de S. Vianna, Pedro C.Q. Zancanaro, Carmélia Matos Reis Tags: Case Report Source Type: journals

Can Sequential TACE And Cryosurgery Improve Survival Times For Patients With HCC?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hepatocellular carcinoma (HCC)--a liver cancer--is recognized as one of the most common cancers in the world that disproportionately affects Southeast Asians and Africans. While there are therapies that possibly provide a cure, surgical removal and liver transplantation are invasive and radical options. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 13, 2009 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Guidelines for cryotherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sharma Vinod K, Khandpur SujayIndian Journal of Dermatology, Venereology, and Leprology 2009 75(8):90-100<b>Introduction:</b> Cryotherapy is a controlled and targeted destruction of diseased tissue by the application of low temperatures. It is a simple, cost-effective, efficacious and esthetically acceptable modality for the treatment of various dermatoses. <b> Indications: </b> It is indicated in the treatment of a wide variety of skin conditions, including benign tumors, acne, pigmented lesions, viral infections, inflammatory dermatoses, infe...
Source: Indian Journal of Dermatology, Venereology and Leprology - August 12, 2009 Category: Dermatology Authors: Sharma Vinod K, Khandpur Sujay Source Type: journals

Sequential TACE and cryosurgery can improve survival times for patients with HCC?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(World Journal of Gastroenterology) In cases where conventional methods may not be an option, cryosurgery may improve survival times for patients with hepatocellular carcinoma. This is by addressing large tumors and by reducing bleeding complications. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 11, 2009 Category: Global & Universal Source Type: news

Sequential use of transarterial chemoembolization and percutaneous cryosurgery for hepatocellular carcinoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Pre-cryosurgical TACE can increase the cryoablation efficacy and decrease its adverse effects, especially bleeding. Sequential TACE and cryosurgery may be the better procedure for unresectable HCC, especially for large HCC. PMID: 19653346 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 5, 2009 Category: Gastroenterology Authors: Xu KC, Niu LZ, Zhou Q, Hu YZ, Guo DH, Liu ZP, Lan B, Mu F, Li YF, Zuo JS Tags: World J Gastroenterol Source Type: journals

Local BCG injection administered to patients with flat condyloma of the cervixEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
HPV infection is the most commonly diagnosed sexually transmitted viral infection . The cervical lesion is typically seen at colposcopy and is known as flat condyloma. Different treatment modalities for flat condyloma range from follow-up to local excision or destruction using the large loop electrosurgical excision procedure (LEEP), laser vaporization, or cryosurgery. Half of all patients treated with LEEP return to the clinic at some point for either recurrence or appearance of a new lesion . In the absence of specific antiviral treatment, the ability to enhance local immunity to overcome the viral infection is worth inv...
Source: International Journal of Gynaecology and Obstetrics - July 24, 2009 Category: OBGYN Authors: Salah T. Fayed, Mohammad Amer, Esam Ammar, Magda Abdel Salam Tags: Brief communications Source Type: journals

Original papers Comparison of cryotherapy and photodynamic therapy in treatment of actinic keratosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: MAL-PDT is an effective method in AK therapy, which makes it possible to achieve better cosmetic results, because it is less destructive and more selective. (Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house)
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - July 22, 2009 Category: Dermatology Source Type: journals

Reply by AuthorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study represents the first of a multistep collaborative process that will result in a standardized evidence-based definition of treatment success for prostate cryoablation. The stated issues are currently being addressed in additional projects specifically designed to further our efforts in a logical progression. With continued analysis of the maturing national registry we anticipate achieving our ultimate goal in the near future. (Source: The Journal of Urology)
Source: The Journal of Urology - July 20, 2009 Category: Urology & Nephrology Tags: Oncology: Prostate/Testis/Penis/Urethra Source Type: journals

Cryosurgery and Impaction Subchondral Bone Graft for the Treatment of Giant Cell Tumor Around the KneeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Giant cell tumors are neoplasms of mesenchymal stromal cells with varied manifestations. There is no uniform accepted treatment protocol for these tumors. Curettage, although an accepted method of treatment, carries a high local recurrence rate. Adjuvant therapies including high-speed burr debridement, cryotherapy, and phenol treatment have been advocated to reduce local recurrence. We have used these adjuvants to determine if improved cure rate with improved outcomes could be attained with regard to local tumor control and functional outcome. Twenty-eight cases of proven giant cell tumors of the di...
Source: HSS Journal - July 10, 2009 Category: Orthopaedics Tags: HSS Journal Source Type: journals

Ultrasound for prostate cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
“A pioneering treatment for the UK's most common male cancer is more successful than surgery or radiotherapy,” The Daily Telegraph reported. The newspaper said that new research shows that intensive ultrasound therapy is as effective as traditional treatments (surgery or radiotherapy) but that side effects are dramatically reduced. This research found reasonably favourable results from high-intensity focused ultrasound (HIFU) treatment in 172 men with localised prostate cancer (cancer that had not spread). It also found that there were relatively low rates of urinary incontinence and erectile dysfunction following tre...
Source: NHS News Feed - July 2, 2009 Category: Consumer Health News Tags: Cancer Medical practice Source Type: news

Methyl Aminolevulinate-PDT for Actinic Keratoses and Superficial Nonmelanoma Skin Cancers.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Methyl aminolevulinate-hydrochloride cream (Metvix(R) [in Canada] and Metvixia(R) [in the US], Galderma) in combination with photodynamic therapy (PDT) provides an effective treatment option for actinic keratoses (AKs), superficial basal cell carcinoma (sBCC), and Bowen's disease (BD). Good clinical outcomes have been reported in the literature. Complete responses (CRs) in AK range from 69% to 93% at 3 months. In sBCC, reported CR rates were from 85% to 93% at 3 months and almost on par with cryosurgery at 60 months (75% vs. 74%). In BD, CR rates were 93% at 3 months and 68% at 2 years. Current evidence has shown that ...
Source: Skin Therapy Letter - June 30, 2009 Category: Dermatology Authors: Ortiz-Policarpio B, Lui H Tags: Skin Therapy Lett Source Type: journals

Treatment of giant cell tumor of long bones: clinical outcome and reconstructive strategy for lower and upper limbs.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Giant cell tumor of bone is a rare and unpredictable lesion. Standard treatment ranges from surgical curettage to wide resection, with reports of varying oncological and functional results. Twenty-three consecutive cases of giant cell tumor of long bones were treated in 10 years. Fifteen men and 8 women had a mean age of 38 years (range, 17-82 years). Average follow-up was 45 months (range, 12-180 months). The most common tumor sites were the proximal tibia (10 cases), distal femur (8), and distal radius (3). All patients remained free of recurrence at the time of final follow-up. Functional outcomes as evaluated by th...
Source: Orthopedics - June 30, 2009 Category: Orthopaedics Authors: Muramatsu K, Ihara K, Taguchi T Tags: Orthopedics Source Type: journals

Long-term follow-up of photodynamic therapy with a self-adhesive 5-aminolaevulinic acid patch: 12 months dataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Twelve months after a single 5-ALA patch-PDT the majority of lesions were still cleared with an excellent cosmetic outcome. 5-ALA patch-PDT proved to be superior to cryosurgery in the noninferiority study setting. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - June 29, 2009 Category: Dermatology Authors: R.-M. Szeimies, E. Stockfleth, G. Popp, F. Borrosch, H. Brüning, R. Dominicus, H. Mensing, U. Reinhold, K. Reich, A.C.E. Moor, M. Stocker, C. Ortland, M. Brunnert, A. Hauschild Source Type: journals

Assessment of cryotherapy for the treatment of verrucous epidermal naevi.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present here our experience with cryosurgery in the treatment of verrucous epidermal naevi. The aim of this study was to determine the efficacy and safety of cryosurgery for the treatment of epidermal naevi. Nine patients with verrucous epidermal naevi and two with extensive unilateral epidermal naevus were treated with cryosurgery. Two cycles of open spray technique were used, 10-15 sec each, depending on the size and extent of the naevus. Ten patients had their naevi treated successfully in 2-5 sessions with two cycles of therapy, and the cosmetic result was excellent with no scarring. One patient showed a relapse wit...
Source: Acta Derm Venereol A... - June 27, 2009 Category: Dermatology Authors: Panagiotopoulos A, Chasapi V, Nikolaou V, Stavropoulos PG, Kafouros K, Petridis A, Katsambas A Tags: Acta Derm Venereol Source Type: journals

Immunocryosurgery for basal cell carcinoma: results of a pilot, prospective, open-label study of cryosurgery during continued imiquimod applicationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions 'Immunocryosurgery' is a promising non-surgical combination modality to treat 'high-risk-for-recurrence BCCs'. Initial evidence is suggestive of an at least additive effect of the two combined modalities. Further studies comparing immunocryosurgery directly with cryosurgery and imiquimod monotherapies will confirm the reported results. None declared. (Source: Journal of the European Academy of Dermatology and Venereology)
Source: Journal of the European Academy of Dermatology and Venereology - June 24, 2009 Category: Dermatology Authors: G Gaitanis, K Nomikos, E Vava, EC Alexopoulos, ID Bassukas Source Type: journals

This Month in Adult UrologyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
An estimated 50,000 men a year in the United States will have prostate specific antigen (PSA) recurrence after either initial radical prostatectomy or radiation therapy. If no further treatment is given, nearly three-quarters of these men will have clinical evidence of recurrent prostate cancer within 5 years of biochemical failure. Many reports document the efficacy and potential complications of local salvage therapies, including salvage radical prostatectomy vs cryotherapy. Pisters et al (page 517) accumulated a series of patients from several institutions who underwent either salvage prostatectomy or cryosurgery. Their...
Source: The Journal of Urology - June 17, 2009 Category: Urology & Nephrology Authors: William D. Steers Source Type: journals

Do physical forces contribute to cryodamage?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To achieve the ultimate goal of both cryosurgery and cryopreservation, a thorough understanding of the processes responsible for cell and tissue damage is desired. The general belief is that cells are damaged primarily due to osmotic effects at slow cooling rates and intracellular ice formation at high cooling rates, together termed the "two factor theory." The present study deals with a third, largely ignored component - mechanical damage. Using pooled bull sperm cells as a model and directional freezing in large volumes, samples were frozen in the presence or absence of glass balls of three different diameters: 70-110, 2...
Source: Biotechnology and Bioengineering - June 3, 2009 Category: Biomedical Science Authors: Joseph Saragusty, Haim Gacitua, Israel Rozenboim, Amir Arav Source Type: journals

Editorial CommentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In an era of evolving technology, one must accept that surgical procedures, even those considered to be rock-solid basic standards of urology, will be challenged and shattered. We have observed this regarding transurethral resection of the prostate for several years. Is it now transurethral resection of bladder tumors? Transitional cell carcinoma (TCC) of the bladder treated with cryosurgery? (Source: Urology)
Source: Urology - May 31, 2009 Category: Urology & Nephrology Authors: Rolf Muschter Tags: Technology and Engineering Source Type: journals

Percutaneous Tumor Ablation: Microencapsulated Echo-guided Interstitial Chemotherapy Combined with Cryosurgery Increases Necrosis in Prostate Cancer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study aimed at confirming the increased growth inhibition (GI) of human prostate tumors produced by a intentionally palliative combination treatment of cryochemotherapy, i.e., partial cryoablation (CA) followed by intratumor partial chemotherapy with injection of microencapsulated 5-fluorouracil (MCC/5FU) at the ice ball (IB) periphery. We report the local effectiveness of cryochemotherapy compared to chemotherapy only with using multiple injections of MCC/5FU spaced out to maximize cumulative effect of sustained release of 5-fluorouracil (5FU) during a 21-day period. Prostate bioluminescent tumor cells - DU145 Luc+ -...
Source: Technology in Cancer Research and Treatment - May 31, 2009 Category: Cancer & Oncology Authors: Le Pivert PJ, Morrison DR, Haddad RS, Renard M, Aller A, Titus K, Doulat J Tags: Technol Cancer Res Treat Source Type: journals

Emergent Group Inc. Strengthens New York Market Presence With Acquisition of Physician PartnershipEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
SUN VALLEY, Calif., May 27, 2009 (GLOBE NEWSWIRE) -- Emergent Group Inc. (NYSE Amex Equities:LZR), a leading provider of mobile medical lasers and surgical equipment, today announced that it has strengthened its presence in the New York market with the acquisition of New York Cryosurgery Equipment, LLC, a physician partnership specializing in rentals of cryosurgery equipment. (Source: Medical News (via PRIMEZONE))
Source: Medical News (via PRIMEZONE) - May 27, 2009 Category: Pharmaceuticals Source Type: news

Prospective follow-up after curettage–cryosurgery for scalp and face skin cancersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions CCS in the treatment of NMSCs is expedient and well tolerated, with no major and few minor complications. When performed as in the present study it produces good cosmetic results in virtually all cases, with an anticipated 97% cure rate after 14 years. CCS is thus a highly viable alternative in the treatment of NMSCs in the face and on the scalp. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - May 25, 2009 Category: Dermatology Authors: B. Lindemalm-Lundstam, J. Dalenbäck Source Type: journals

Cryosurgery Combined with Radioactive Seeds and Release-controlled Chemical Drugs Implantation for the Treatment of Lung CarcinomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Cryosurgery is a rapid modality for the debulking of pulmoanry tumor and concurrent therapy of radioactive seeds and release-controlled drugs implantation could effectively treat the remaining tumor. It is a rapid and effective method for the treatment of advanced stage lung cancer. (Source: Chinese Journal of Lung Cancer)
Source: Chinese Journal of Lung Cancer - May 20, 2009 Category: Cancer & Oncology Source Type: journals

Combination of cryosurgery and topical imiquimod: Does timing matter for successful immunocryosurgery?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19426725 [PubMed - as supplied by publisher] (Source: Cryobiology)
Source: Cryobiology - May 5, 2009 Category: Biology Authors: Bassukas ID, Gaitanis G Tags: Cryobiology Source Type: journals

Cryosurgery—its development and futureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Therapeutic use of cold temperature has existed for a long time in the medical setting, first and foremost for its anaesthetising effects. A review of the history of cryosurgery shows that it has progressed in leaps, and that each leap has usually been triggered by immediately preceding technologic innovations. The fact that the application of temperatures lower than −100°C could induce cell death was supported by Schreuder's investigations. Today, the major aim of cryosurgery is destruction of diseased tissue, such as benign and malignant neoplasms, by application of exceedingly low temperature. Over the past 4 decades...
Source: International Journal of Oral and Maxillofacial Surgery - May 1, 2009 Category: ENT & OMF Authors: H. Mahendra, M. Kohli, N. Sharma, L.C. Gupta Tags: Oral Presentations Source Type: journals

A breakthrough in cryosurgeryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Case reports: Online FirstDOI 10.1007/s00464-001-4228-4Authors M. A. SikmaJ. L. L. M. CoenenC. KloosterzielB. A. A. M. van HasseltT. J. M. Reuers Journal Surgical EndoscopyOnline ISSN 1432-2218Print ISSN 0930-2794 Journal Volume Volume 16 Journal Issue Volume 16, Number 5 / May, 2002 (Source: Surgical Endoscopy)
Source: Surgical Endoscopy - April 24, 2009 Category: Surgery Tags: Surgical Endoscopy Source Type: journals

Focal therapy for prostate cancer: revolution or evolution?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The face of prostate cancer has been dramatically changed since the late 1980s when PSA was introduced as a clinical screening tool. More men are diagnosed with small foci of cancers instead of the advanced disease evident prior to PSA screening. Treatment options for these smaller tumors consist of expectant management, radiation therapy (brachytherapy and external beam radiotherapy) and surgery (cryosurgical ablation and radical prostatectomy). In the highly select patient, cancer specific survival employing any of these treatment options is excellent, however morbidity from these interventions are significant. Thus, the...
Source: BMC Urology - Latest articles - April 23, 2009 Category: Urology & Nephrology Authors: Ryan Turpen and Charles J. Rosser Source Type: journals

Update on cryotherapy for localized prostate cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Stage migration has led to an increased incidence of localized and low-risk prostate cancer. Intermediate-term data are emerging on the efficacy of cryotherapy, but direct comparison to other therapeutic modalities is difficult as the parameters for recurrence are not well defined. Studies using the American Society for Therapeutic Radiation and Oncology and the Phoenix (nadir plus 2) criteria for biochemical recurrence show that primary cryotherapy appears to be comparable for low-risk prostate cancer as other treatment modalities. In addition, health-related quality-of-life measures have improved ...
Source: Current Urology Reports - April 21, 2009 Category: Urology & Nephrology Tags: Current Urology Reports Source Type: journals