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Imaging of prostate cancer local recurrences: why and how?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion These recent advances in imaging may improve the outcome of salvage therapies (by improving patient selection and treatment targeting) and should open the way to focal salvage treatments in the near future. Content Type Journal ArticleCategory UrogenitalDOI 10.1007/s00330-009-1647-4Authors Olivier Rouvière, Université de Lyon Lyon 69003 FranceThierry Vitry, Service d’imagerie urinaire et vasculaire Hospices Civils de Lyon, Hôpital Edouard Herriot Lyon 69003 FranceDenis Lyonnet, Université de Lyon Lyon 69003 France Journal European RadiologyOnline ISSN 1432-1084Print ISSN 0938-79...
Source: European Radiology - November 18, 2009 Category: Radiology Tags: European Radiology Source Type: journals

We need better randomized comparison trials of prostate cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
More than 50 years after the first randomized oncology trial, the number of randomized trials comparing differing primary treatments for prostate cancer is disappointing. One of these rare, randomized primary treatment comparisons appears in this edition of Cancer, and the investigators are to be congratulated for their efforts comparing cryotherapy with external beam radiotherapy. (Source: Cancer)
Source: Cancer - November 18, 2009 Category: Cancer & Oncology Authors: W. Robert Lee Source Type: journals

A pretreatment nomogram predicting biochemical failure after salvage cryotherapy for locally recurrent prostate cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To gather a pooled database from six tertiary-care referral centres using salvage cryotherapy (SC) for locally recurrent prostate cancer, and develop a pretreatment nomogram allowing a prediction of the probability of biochemical failure after SC, based on pretreatment clinical variables. We retrospectively analysed 797 men treated at six tertiary-care referral centres with SC for locally recurrent disease after primary radiotherapy with curative intent. The median duration of follow-up from the time of SC to the date of last contact was 3.4 years. The primary study endpoint was biochemical failure, defined as a serum pros...
Source: BJU International - November 17, 2009 Category: Urology & Nephrology Authors: Philippe E. Spiess, Aaron E. Katz, Joseph L. Chin, Duke Bahn, Jeffrey K. Cohen, Katsuto Shinohara, Mike Hernandez, Julie Bossier, Wassim Kassouf, Louis L. Pisters Source Type: journals

Porokeratosis palmaris et plantaris disseminata or a disseminated late-onset variant of porokeratotic eccrine ostial and dermal ductal nevus (PEODDN) with follicular involvement.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 48-year-old woman presented with a four-year history of pruritic, hyperkeratotic, spiny papules that began on her chest and spread to her extremities, groin, palms, face, and scalp where it caused non-scarring alopecia. Histopathologic features included cornoid lamella, which is the hallmark of porokeratosis. However, the patient's constellation of findings does not meet diagnostic criteria for any of the five clinical variants of porokeratosis. Her presentation is most compatible with either porokeratosis palmaris et plantaris disseminata (PPPD), which is a rare variant of punctate porokeratosis that can involve any...
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Hartman R, Rizzo C, Patel R, Kamino H, Shupack JL Tags: Dermatol Online J Source Type: journals

Effects of the whole-body cryotherapy on NTproBNP, hsCRP and troponin I in athletesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Whole-body cryotherapy refers to brief exposure to very cold air for treating symptoms of various illnesses. In sports medicine, whole-body cryotherapy is administered to improve recovery from muscular trauma. As specific studies are lacking, we measured cardiac markers in 10 top-level rugby players of the Italian National team before and after a 1-week course of daily sessions of whole-body cryotherapy. All subjects continued with the same training workload as that of the previous weeks. N-terminal pro B-type natriuretic peptide (NTproBNP) levels increased but remained within the normal range, whilst troponin I ...
Source: Journal of Science and Medicine in Sport - November 1, 2009 Category: Sports Medicine Authors: Giuseppe Banfi, Gianluca Melegati, Alessandra Barassi, Gianlodovico Melzi d’Eril Tags: SPORTS MEDICINE Source Type: journals

[Interventional radiology procedures in the treatment of bone metastasis.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Over the last ten years, there has been much development in the treatment of bone metastases using percutaneous image-guided interventional radiology procedures. They are helpful in the managment of patients resulting in stabilization of bone lysis in order to achieve additional biomechanical stability and in significant symptomatic relief. Vertebroplasty consisting in an injection of an acrylic cement into a structurally weakened or destructed bone plays a major role in the management of specific bone weakening. Advances have been made also with the application of thermoablation procedures to bone tumors (radiofrequen...
Source: Bulletin du Cancer - October 27, 2009 Category: Cancer & Oncology Authors: Palussière J, Dixmerias F, Buy X, Descat E, Bonichon F, Debled M, Pointillart V, Gangi A Tags: Bull Cancer Source Type: journals

Randomized Trial Of External Beam Radiotherapy Versus Cryoablation In Patients With Localized Prostate Cancer: Quality Of Life OutcomesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
UroToday.com - In the online edition of Cancer, Dr. John Robinson and associates present QoL outcomes from a single institution randomized trial comparing external beam radiotherapy (EBRT) with cryotherapy for localized prostate cancer (CaP). They previously reported a non-inferiority oncologic outcome for cryotherapy in this study. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 26, 2009 Category: Consumer Health News Tags: Prostate / Prostate Cancer Source Type: news

Vasoproliferative retinal tumours in a Swedish populationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: VPRTs are benign intraretinal changes. Several complications are associated with this condition. All patients in this study had symptom-giving tumours and six patients (six eyes) already had profound macular oedema at presentation. In these cases, when complications have already developed, the final visual prognosis is poor, thereby making it important to detect these tumours early. The patient who received anti-vascular endothelial growth factor (VEGF; Lucentis) therapy showed a slow improvement and distinct regression in exudations during the follow-up time. However, no increase in visual acuity was seen. At ...
Source: Acta Ophthalmologica - October 22, 2009 Category: Opthalmology Authors: Karim Makdoumi, Sven Crafoord Source Type: journals

Frostbite used to fight cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Frostbite is being used by Scottish doctors to fight prostate cancer tumours in a procedure called cryotherapy, it has been revealed. (Source: Nursing Times Breaking News)
Source: Nursing Times Breaking News - October 12, 2009 Category: Nursing Source Type: news

Interstitial Laser Therapy of Breast Fibroadenomas With 6 and 8 Year Follow-UpEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Fibroadenomas are non-cancerous breast tumors commonly seen in teenagers but also found in women at the time of first mammogram. They have distinct physical findings and imaging features but the definitive diagnosis is made by ultrasound or stereotactic guided needle biopsy. Treatment options are observation or surgical removal. Recently, removal by ultrasound-guided technique has been reported. Alternatively, the tumor may be ablated within the breast by cold (cryotherapy) or by heat (laser, radiofrequency, focused ultrasound and microwave). In this paper the laser treatment in two patients, one with bilateral f...
Source: The Breast Journal - October 11, 2009 Category: Cancer & Oncology Authors: K. Dowlatshahi, S. Wadhwani, R. Alvarado, C. Valadez, J. Dieschbourg Source Type: journals

Perfusion-CT monitoring of cryo-ablated renal cells tumorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Perfusion CT seems to be a feasible and promising technique in monitoring the effects of cryoablation therapy. (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - October 9, 2009 Category: Cancer & Oncology Authors: Ettore SquillaciGuglielmo ManentiCarmelo CiccioFrancesca NuceraPierluigi BoveGiuseppe VespasianiLaura RussolilloGiovanni Simonetti Source Type: journals

Comparative Study on the Efficacy, Safety, and Acceptability of Imiquimod 5% Cream versus Cryotherapy for Molluscum Contagiosum in ChildrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: To compare the efficacy, safety and acceptability of imiquimod (IMQ) 5% cream with cryotherapy for the treatment of molluscum contagiosum (MC) in children. Prospective, randomized, comparative, observer blinded study. A total of 74 children, with MC were divided randomly to receive treatment with either IMQ 5% cream (group A) 5 days a week or cryotherapy (group B) once a week until clinical cure or up to a maximum of 16 weeks. All the patients were followed up weekly during active treatment. The patients were followed-up for 6 months after clinical cure to look for recurrence. In the IMQ group (group A), the over...
Source: Pediatric Dermatology - October 3, 2009 Category: Dermatology Authors: Nawaf Al-Mutairi, Azari Al-Doukhi, Shahat Al-Farag, Ahmad Al-Haddad Source Type: journals

Cryotherapy for Breast Cancer: A Feasibility Study without ExcisionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: In conjunction with thorough pre- and postablation MR imaging, CT/US-guided multiprobe BC safely achieved 1 cm visible ice beyond tumor margins with minimal discomfort, good cosmesis, and no short-term local tumor recurrences. (Source: Journal of Vascular and Interventional Radiology : JVIR)
Source: Journal of Vascular and Interventional Radiology : JVIR - September 30, 2009 Category: Radiology Authors: Peter J. Littrup, Bassel Jallad, Priti Chandiwala-Mody, Monica D'Agostini, Barbara A. Adam, David Bouwman Tags: Clinical Studies Source Type: journals

Topical mitomycin following cryotherapy for treatment of recurrent ocular surface melanoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Topical mitomycin following cryotherapy for treatment of recurrent ocular surface melanoma. Can J Ophthalmol. 2009 Oct;44(5):e41 Authors: Rudkin AK, Muecke JS PMID: 19798814 [PubMed - in process] (Source: Canadian Journal of Ophthalmology)
Source: Canadian Journal of Ophthalmology - September 30, 2009 Category: Opthalmology Authors: Rudkin AK, Muecke JS Tags: Can J Ophthalmol Source Type: journals

Interventional endoscopic ultrasound: the next frontier in gastrointestinal endoscopy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Endoscopic ultrasound (EUS) has become well established as a diagnostic modality in gastrointestinal cancer staging. It offers high-resolution imaging and fine-needle biopsy, which is essential in tumor and nodal staging of gastrointestinal cancers. In the recent decade, however, many therapeutic applications of EUS have become possible. Currently, interventional EUS endoscopy involves celiac plexus neurolysis, pseudocyst drainage, and intratumoral fine-needle injection therapy for inoperable pancreatic malignancy. Emerging techniques include the accurate endoscopic delivery of radioactive beads to localize tumor thera...
Source: The American Journal of the Medical Sciences - September 30, 2009 Category: Journals (General) Authors: Sreenarasimhaiah J Tags: Am J Med Sci Source Type: journals

Galil Medical Announces Establishment of Global Headquarters in Minneapolis, MNEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
MINNEAPOLIS, Sept. 30 (HSMN NewsFeed) -- Galil Medical, a global leader in minimally invasive cryotherapy treatments for cancers and other disorders, announced today that it is establishing its new Global Headquarters in Minneapolis, MN. The company is e... DevicesGalil Medical (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - September 30, 2009 Category: Pharmaceuticals Source Type: news

Galil establishes new HQEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cryotherapy firm Galil Medical plans to open a new global headquarters at a facility in Arden Hills, MN. (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - September 30, 2009 Category: Radiology Source Type: info

[AV nodal reentrant tachycardias: What is the place of cryoablation?]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article reviews principles of cryotherapy, its main results in ablation of AV nodal reentrant tachycardias, its advantages and disadvantages. A proposal is made about its indications. PMID: 19819422 [PubMed - as supplied by publisher] (Source: Annales de Cardiologie et d'Angeiologie)
Source: Annales de Cardiologie et d'Angeiologie - September 24, 2009 Category: Cardiology Authors: Amara W, De Sisti A, Tonet J Tags: Ann Cardiol Angeiol (Paris) Source Type: journals

Warts (non-genital)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
New evidence; conclusion confirmed for: Photodynamic treatment One systematic review added. It found that photodynamic treatment was more effective at wart clearance than placebo or cryotherapy, and that neutral red photodynamic treatment and proflavine photodynamic treatment have similar effects. Categorisation unchanged (Likely to be beneficial). Intralesional bleomycin Data from one systematic review updated, and one RCT added. The RCT found that intralesional bleomycin increased wart clearance compared with placebo. Categorisation unchanged (unknown effectiveness). ...
Source: Clinical Evidence - September 24, 2009 Category: Journals (General) Source Type: journals

Cryotherapy of sclerotomy sites for prevention of late post-vitrectomy diabetic hemorrhage: a randomized clinical trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Cryotherapy of the sclerotomy sites at the end of the operation is not helpful for prevention of late post-vitrectomy diabetic hemorrhage, and it may even increase this risk. Content Type Journal ArticleCategory Retinal DisordersDOI 10.1007/s00417-009-1182-7Authors Morteza Entezari, Shahid Beheshti University (M.C.) Department of Ophthalmology, Imam Hossein Medical Center, Ophthalmic Research Center Tehran IranAlireza Ramezani, Shahid Beheshti University (M.C.) Department of Ophthalmology, Imam Hossein Medical Center, Ophthalmic Research Center Tehran IranHamid Ahmadieh, Shahid Beheshti Uni...
Source: Graefe's Archive for Clinical and Experimental Ophthalmology - September 24, 2009 Category: Opthalmology Tags: Graefe's Archive for Clinical and Experimental Ophthalmology Source Type: journals

Cryotherapy as the treatment modality of postcoital bleeding: A randomised clinical trial of efficacy and safetyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Our study demonstrated that cryotherapy is a safe and an effective treatment for postcoital bleeding. (Source: The Australian and New Zealand Journal of Obstetrics and Gynaecology)
Source: The Australian and New Zealand Journal of Obstetrics and Gynaecology - September 23, 2009 Category: OBGYN Authors: Grace Wing Shan KONG, So Fan YIM, Tak Hong CHEUNG, Tony Kwok Hung CHUNG Tags: ORIGINAL ARTICLES Source Type: journals

Early experience with percutaneous cryoablation of extra-abdominal desmoid tumorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Cryoablation appears to be an effective alternative treatment for the achievement of local control of small and moderately sized EAD tumors, but it is likely of limited use in patients with larger tumors that have untreatable regions due to involvement of vital structures. Continued research evaluating cryoablation for the treatment of EAD tumors is needed. Content Type Journal ArticleCategory Technical ReportDOI 10.1007/s00256-009-0801-zAuthors Jennifer L. Kujak, Mayo Clinic Arizona Department of Radiology 5777 East Mayo Boulevard Phoenix AZ 85054 USAPatrick T. Liu, Mayo Clinic Arizona Dep...
Source: Skeletal Radiology - September 20, 2009 Category: Radiology Tags: Skeletal Radiology Source Type: journals

Cryotherapy Proves to be Effective in Treating Esophageal Cancer, University of Maryland Study ShowsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: University of Maryland School of Medicine News Headlines)
Source: University of Maryland School of Medicine News Headlines - August 29, 2009 Category: Universities & Medical Training Source Type: news

Cryotherapy Proves to be Effective in Treating Esophageal Cancer, University of Maryland Study ShowsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study demonstrates that spray cryotherapy is effective in eliminating esophageal cancer in a substantial portion of cases. It is also an excellent alternative treatment for patients with localized disease who are not eligible for or choose not to have standard therapies,” says Dr. Greenwald, the lead author of the study, which was conducted at the University of Maryland Medical Center and nine other institutions. He recently presented the initial results of the study at the 2009 Digestive Disease Week (DDW) conference in Chicago. “We see a number of patients, particularly older people, who are not able to h...
Source: University of Maryland School of Medicine News Headlines - August 28, 2009 Category: Universities & Medical Training Source Type: news

Cryotherapy Proves to be Effective in Treating Esophageal Cancer, University of Maryland School of Medicine Study ShowsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study demonstrates that spray cryotherapy is effective in eliminating esophageal cancer in a substantial portion of cases. It is also an excellent alternative treatment for patients with localized disease who are not eligible for or choose not to have standard therapies,” says Dr. Greenwald, the lead author of the study, which was conducted at the University of Maryland Medical Center and nine other institutions. He recently presented the initial results of the study at the 2009 Digestive Disease Week (DDW) conference in Chicago. “We see a number of patients, particularly older people, who are not able to h...
Source: University of Maryland School of Medicine News Headlines - August 28, 2009 Category: Universities & Medical Training Source Type: news

Minimally-invasive technologies in uro-oncology: The role of cryotherapy, HIFU and photodynamic therapy in whole gland and focal therapy of localised prostate cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article reviews the evidence for cryotherapy, high intensity focused ultrasound (HIFU) and photodynamic therapy in the treatment of localised prostate cancer. These ablative technologies can deliver a minimally invasive, day case treatment with effective early cancer control and low genitourinary morbidity. In addition, all have the ability to deliver focal therapy of only the malignant lesions within the prostate. (Source: Surgical Oncology)
Source: Surgical Oncology - August 27, 2009 Category: Surgery Authors: Hashim Uddin Ahmed, Caroline Moore, Mark Emberton Tags: Treatment Principles Source Type: journals

History of prostate cancer treatmentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: The last two decades have seen great advancements in our understanding of the prostate anatomy and approach including laparoscopic and robotic techniques. One should not however, forget that the techniques evolved with time. The history of developments in prostate cancer surgery, radiotherapy and hormonal therapy is fascinating and urologists through the ages had the quest to find an ideal treatment for prostate cancer in spite of their limitations of resources and understanding. Surgeons have now practiced radical prostatectomy for prostate cancer for over 100 years. Initially feared because of its complications...
Source: Surgical Oncology - August 27, 2009 Category: Surgery Authors: Seshadri Sriprasad, Mark R. Feneley, Peter M. Thompson Tags: History Source Type: journals

Impact of Pneumoperitoneum on Renal CryotherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Journal of Endourology , Vol. 0, No. 0. (Source: Journal of Endourology)
Source: Journal of Endourology - August 20, 2009 Category: Urology & Nephrology Tags: article Source Type: journals

Locally Recurrent Prostate Cancer After Initial Radiation Therapy: A Comparison Of Salvage Radical Prostatectomy Versus Cryotherapy...Ranked "Changes Clinical Practice" from F1000Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Go for the cure in some patients with recurrent prostate cancer and avoid the knee-jerk response of androgen therapy. Faculty of 1000 Medicine (Source: Medscape Urology Headlines)
Source: Medscape Urology Headlines - August 14, 2009 Category: Urology & Nephrology Tags: Internal Medicine Source Type: info

Guidelines for cryotherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sharma Vinod K, Khandpur SujayIndian Journal of Dermatology, Venereology, and Leprology 2009 75(8):90-100<b>Introduction:</b> Cryotherapy is a controlled and targeted destruction of diseased tissue by the application of low temperatures. It is a simple, cost-effective, efficacious and esthetically acceptable modality for the treatment of various dermatoses. <b> Indications: </b> It is indicated in the treatment of a wide variety of skin conditions, including benign tumors, acne, pigmented lesions, viral infections, inflammatory dermatoses, infe...
Source: Indian Journal of Dermatology, Venereology and Leprology - August 12, 2009 Category: Dermatology Authors: Sharma Vinod K, Khandpur Sujay Source Type: journals

Plus DiseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Our understanding of plus disease as an important sign for severe retinopathy of prematurity (ROP) has gradually been refined over the past 30 years. As a result of the Early Treatment for ROP (ETROP) randomized trial, the presence of plus disease is now the primary indication for laser treatment. Since the Cryotherapy for ROP trial first introduced a standard photograph as the minimum abnormality necessary for diagnosing plus disease, an intermediate level of vascular dilatation and tortuosity (pre-plus disease) has been defined. However, the recognition of plus disease remains problematic, primarily because of ...
Source: Survey of Ophthalmology - August 9, 2009 Category: Opthalmology Authors: Bradley V. Davitt, David K. Wallace Tags: Major Review Source Type: journals

[Cryotherapy.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cryotherapy is a form of physical therapy that can be applied locally and systemically. Local cryotherapy administered for instance as cold packs, cold air or sprays lowers skin and tissue temperature and subsequently decreases neuronal activity and tissue blood flow. In clinical trials cryotherapy showed analgetic effects and reduced local edema; this treatment is therefore an option in patients with painful and inflammatory rheumatic diseases and after traumatic injuries.Only scant experimental and clinical data are available for whole body cryotherapy at -110 degrees C. The analgetic effects demonstrated so far and ...
Source: Zeitschrift fur Rheumatologie - August 4, 2009 Category: Rheumatology Authors: Hermann J Tags: Z Rheumatol Source Type: journals

Enhancing prostate cancer cryotherapy using tumour necrosis factor related apoptosis-inducing ligand (TRAIL) sensitisation in an in vitro cryotherapy model.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study we investigate the effect of TRAIL as a sensitising agent to enhance the effects of cryotherapy on prostate cancer cells.Prostate cancer cells were cooled using Endocare cryo-system to mimic temperatures achieved during clinical cryotherapy. The effects of TRAIL, cryotherapy or combination of both treatment on DU-145 and PC-3 were evaluated. Viability and mode of cell death was assessed following treatment.Cryotherapy did not result in complete cell death at temperature -40 degrees C. Cells died by both necrosis and apoptosis. Cells which survived freeze-thaw cycle became more sensitive to a second freezing i...
Source: Cryobiology - July 27, 2009 Category: Biology Authors: Ismail M, Morgan R, Harrington K, Davies J, Pandha H Tags: Cryobiology Source Type: journals

Telegraph Readers' ClinicEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Our panel of experts answers your health and wellbeing questions. (Source: Telegraph Health)
Source: Telegraph Health - July 24, 2009 Category: Consumer Health News Tags: verruca pain wart foot chiropodist cryotherapy Podiatrist Source Type: news

Original papers Comparison of cryotherapy and photodynamic therapy in treatment of actinic keratosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: MAL-PDT is an effective method in AK therapy, which makes it possible to achieve better cosmetic results, because it is less destructive and more selective. (Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house)
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - July 22, 2009 Category: Dermatology Source Type: journals

Frostbite of the Feet After Cryotherapy: A Report of Two CasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The use of cryotherapy for the reduction of postoperative swelling and pain has become commonplace in orthopedic, podiatric, and cosmetic surgery. Prolonged exposure to extreme cold may induce an injury nearly identical to that of frostbite. The authors report on 2 patients who underwent podiatric orthopedic surgery and were exposed to prolonged cold therapy, which resulted in limb-threatening problems. Both patients had prolonged and essentially uninterrupted application of cryotherapy for 4 to 7 days, resulting in rewarming injuries of tissue necrosis. A team of specialists used limb salvage therapy to successfully treat...
Source: Journal of Foot and Ankle Surgery - July 16, 2009 Category: Orthopaedics Authors: William C. Brown, David B. Hahn Tags: Case Reports Source Type: journals

Giant condyloma with demise secondary to meningococcemia in an infant boyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Human papilloma virus (HPV) is the most common sexually transmitted disease among adults in the USA; however, the presence of HPV in infants is rare. Condyloma acuminata, a cutaneous, fungating lesion caused by HPV, has a generally mild course that often resolves spontaneously or can be managed both medically and surgically. Typical treatments for condyloma include imiquimoid cream, podofilox gel, podophyllin resin, cryotherapy, laser surgery, tangential shave excision, and electrocautery. Rapidly progressing condyloma acuminata followed by a fatal course of Neisseria meningitis in an infant is an extremely rare ...
Source: Journal of Pediatric Urology - July 15, 2009 Category: Urology & Nephrology Authors: Ronak A. Gor, Justine M. Schober Tags: Case Reports Source Type: journals

Better outcomes after salvage prostate surgery than cryotherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Young patients with recurrent prostate cancer after radiotherapy should undergo salvage radical prostatectomy, as it offers better outcomes than salvage cryotherapy, conclude US researchers. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - July 15, 2009 Category: Cancer & Oncology Source Type: news

Better outcomes after salvage prostate surgery than cryotherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Young patients with recurrent prostate cancer after radiotherapy should undergo salvage radical prostatectomy, as it offers better outcomes than salvage cryotherapy, conclude US researchers. (Source: MedWire News - Prostate Cancer)
Source: MedWire News - Prostate Cancer - July 15, 2009 Category: Cancer & Oncology Source Type: news

Management of Small Renal MassesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Surgical excision of renal cell carcinoma is the current standard of care for localized disease. Series for small renal masses treated with surgery demonstrate excellent oncologic outcomes with 5-year survival rates over 95%. Minimally invasive ablative technologies, such as cryotherapy and radiofrequency ablation, have recently emerged with similar short- and intermediate-term results. Additionally, recent data on active surveillance have demonstrated survival rates comparable to surgery and ablation in selected patient populations. We review the currently available data regarding the management of small renal masses by e...
Source: Seminars in Ultrasound CT and MRI - July 14, 2009 Category: Radiology Authors: David A. Kunkle, Alexander Kutikov, Robert G. Uzzo Source Type: journals

Cryosurgery and Impaction Subchondral Bone Graft for the Treatment of Giant Cell Tumor Around the KneeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Giant cell tumors are neoplasms of mesenchymal stromal cells with varied manifestations. There is no uniform accepted treatment protocol for these tumors. Curettage, although an accepted method of treatment, carries a high local recurrence rate. Adjuvant therapies including high-speed burr debridement, cryotherapy, and phenol treatment have been advocated to reduce local recurrence. We have used these adjuvants to determine if improved cure rate with improved outcomes could be attained with regard to local tumor control and functional outcome. Twenty-eight cases of proven giant cell tumors of the di...
Source: HSS Journal - July 10, 2009 Category: Orthopaedics Tags: HSS Journal Source Type: journals

Sympathetic ophthalmia following vitreoretinal surgeryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective is to discuss the characteristics of three patients who developed sympathetic ophthalmia following vitreoretinal surgery. The first case was a 29-year-old man who underwent placement of an encircling band, pars plana vitrectomy, foreign body removal, endolaser photocoagulation, transscleral cryotherapy, and silicone oil injection due to a retained foreign body 3 months after a corneoscleral rupture repair. He experienced visual loss in the fellow eye 2 months after the vitrectomy. An extensive exudative detachment was detected in the fellow eye. Sympathetic ophthalmia was diagnosed and systemic ...
Source: International Ophthalmology - July 9, 2009 Category: Opthalmology Tags: International Ophthalmology Source Type: journals

Dramatic clearance of a recalcitrant acral viral wart using methyl aminolevulinate-red light photodynamic therapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 20-year-old man presented with a 3-month history of a viral wart located on his right thumb. Cryotherapy was administered weekly to the wart over 5 months without any significant improvement. A decision was made to treat the wart with red light photodynamic therapy (PDT) using topical methyl aminolevulinate (MAL) administered as three treatments 1-week apart. The patient was reviewed 4 weeks after the third treatment and the wart was found to have cleared completely. Three months after the last treatment, there remained no clinical evidence of recurrence of the wart. Pain was the main problem with the treatment but it wa...
Source: Photodermatology, Photoimmunology and Photomedicine - July 7, 2009 Category: Radiology Authors: Wei-Sheng Chong, Gregory Yirun Michael Kang Tags: Brief communications Source Type: journals

Recurrent lip fissuresEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chronic lip fissures affect about 0.6% of the population and affect both the upper and lower lip equally. They are usually found in the sagittal plane of the vermillion and are 4 times more likely to affect men than women. They are not related to either smoking or outdoor environmental exposure. Because of the pain, unsightly appearance, and tendency to recur, patients may come for professional treatment. Conservative treatment is not always effective, and excision and cryotherapy are effective but problematic. A resurfacing technique using a carbon dioxide laser was used for 12 chronic lip fissures, with results measured ...
Source: Dental Abstracts - June 30, 2009 Category: Dentistry Tags: Lasers Source Type: journals

Long-term AK clearance: Topical imiquimod outperforms cryotherapy, 5-FUEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Analysis of a recent trial shows that topical imiquimod outperforms cryotherapy and topical 5-FU in terms of clinical and cosmetic outcomes in patients with actinic keratoses 12 months after treatment, an expert says. (Source: Modern Medicine)
Source: Modern Medicine - June 28, 2009 Category: Journals (General) Source Type: info

Assessment of cryotherapy for the treatment of verrucous epidermal naevi.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present here our experience with cryosurgery in the treatment of verrucous epidermal naevi. The aim of this study was to determine the efficacy and safety of cryosurgery for the treatment of epidermal naevi. Nine patients with verrucous epidermal naevi and two with extensive unilateral epidermal naevus were treated with cryosurgery. Two cycles of open spray technique were used, 10-15 sec each, depending on the size and extent of the naevus. Ten patients had their naevi treated successfully in 2-5 sessions with two cycles of therapy, and the cosmetic result was excellent with no scarring. One patient showed a relapse wit...
Source: Acta Derm Venereol A... - June 27, 2009 Category: Dermatology Authors: Panagiotopoulos A, Chasapi V, Nikolaou V, Stavropoulos PG, Kafouros K, Petridis A, Katsambas A Tags: Acta Derm Venereol Source Type: journals

Treatability by Cryotherapy in a Screen-and-Treat Strategy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
One half of HPV-positive women, diagnosed subsequently to have persistent HPV or CIN2+, are not immediately treatable by cryotherapy, suggesting that other low-technology treatment might be needed.Page: 174DOI: 10.1097/LGT.0b013e3181909f30Authors: Gage, Julia C. PhD, MPH 1; Rodriguez, Ana Cecilia MD 2; Schiffman, Mark MD, MPH 1; Garcia, Francisco M. MD, MPH 3; Long, Rodney L. MA 4; Budihas, Scott R. BS 4; Herrero, Rolando MD 2; Burk, Robert D. MD 5; Jeronimo, Jose MD 6 (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - June 26, 2009 Category: OBGYN Tags: Abstract HTML PDF (96 K) Source Type: journals

An open-label, prospective trial of cryospray ablation for Barrett's esophagus high-grade dysplasia and early esophageal cancer in high-risk patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Patients with BE and HGD or IMCA have a positive response to endoscopic cryotherapy at 1-year follow-up. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - June 25, 2009 Category: Gastroenterology Authors: John A. Dumot, John J. Vargo, Gary W. Falk, Lorraine Frey, Rocio Lopez, Thomas W. Rice Tags: Clinical Endoscopy Source Type: journals

Galil Medical Ltd. Sues HealthTronics for Interfering with the Galil/Endocare Merger AgreementEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Galil Asks Delaware Chancery Court To Enjoin HealthTronics' Tender Offer For Endocare YOKNEAM, Israel and PLYMOUTH MEETING, Pa., June 22 (HSMN NewsFeed) -- Galil Medical Ltd., a global cryotherapy company, filed suit against HealthTronics, Inc., late ... Devices, Mergers & Acquisitions, LitigationGalil Medical, HealthTronics, Endocare (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 22, 2009 Category: Pharmaceuticals Source Type: news

This Month in Adult UrologyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
An estimated 50,000 men a year in the United States will have prostate specific antigen (PSA) recurrence after either initial radical prostatectomy or radiation therapy. If no further treatment is given, nearly three-quarters of these men will have clinical evidence of recurrent prostate cancer within 5 years of biochemical failure. Many reports document the efficacy and potential complications of local salvage therapies, including salvage radical prostatectomy vs cryotherapy. Pisters et al (page 517) accumulated a series of patients from several institutions who underwent either salvage prostatectomy or cryosurgery. Their...
Source: The Journal of Urology - June 17, 2009 Category: Urology & Nephrology Authors: William D. Steers Source Type: journals