Drug Development for the Treatment of Congenital Cytomegalovirus Infection and Neonatal Enterovirus Infection - 05/07/2024
The Food and Drug Administration is holding a public, two-day workshop entitled Development of Drugs for the Treatment of Congenital Cytomegalovirus (CMV) Infection and Neonatal Enterovirus Infection. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - March 13, 2024 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Oral Herpes Tied to Double Dementia Risk in Older Adults Oral Herpes Tied to Double Dementia Risk in Older Adults
Herpes simplex virus (HSV) is associated with an increased risk for dementia but cytomegalovirus (CMV) is not, new observational data suggested.Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - March 1, 2024 Category: Psychiatry Tags: Neurology & Neurosurgery Source Type: news

Vaccine shows promise against CMV, a virus that causes birth defects
An experimental mRNA vaccine against human cytomegalovirus (CMV), a common virus that can infect babies during pregnancy, elicited some of the most promising immune responses to date of any CMV vaccine candidate, according to a study by Weill Cornell Medicine investigators. (Source: World Pharma News)
Source: World Pharma News - February 12, 2024 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Longer Letermovir Prophylaxis Reduced Risk of Cytomegalovirus Infection After HSCT
(MedPage Today) -- Extending the duration of letermovir (Prevymis) prophylaxis following hematopoietic stem cell transplantation (HSCT) was effective in reducing the risk of late clinically significant cytomegalovirus infection, a phase III randomized... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 27, 2023 Category: Hematology Source Type: news

How Late Can You Give Routine Newborn Care?
Discussion Routine newborn screening and treatment is focused on assisting the infant’s transition to extrauterine life, screening for health problems that may or may not be easily identifiable, and preventing acute or chronic health problems. Healthy infants begin with healthy pregnancies including risk factor assessment and screening of mothers. Such routine maternal screening and treatment does or may include glucose tolerance tests, ultrasound examinations, screenings for maternal blood type (with appropriate administration of Rho(D) immunoglobulin if appropriate), Hepatitis B, Neisseria gonorrhea, Chlamydia, Cyt...
Source: PediatricEducation.org - November 20, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

How Late Can You Give Routine Newborn Care?
Discussion Routine newborn screening and treatment is focused on assisting the infant’s transition to extrauterine life, screening for health problems that may or may not be easily identifiable, and preventing acute or chronic health problems. Healthy infants begin with healthy pregnancies including risk factor assessment and screening of mothers. Such routine maternal screening and treatment does or may include glucose tolerance tests, ultrasound examinations, screenings for maternal blood type (with appropriate administration of Rho(D) immunoglobulin if appropriate), Hepatitis B, Neisseria gonorrhea, Chlamydia, Cyt...
Source: PediatricEducation.org - November 20, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Novel Vaccines Promising for Chikungunya, Cytomegalovirus
(MedPage Today) -- BOSTON -- Vaccine candidates for chikungunya virus and for the ubiquitous cytomegalovirus performed well in human clinical trials, researchers reported here at the annual IDWeek meeting. In two phase III trials, the adjuvanted... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - October 17, 2023 Category: Infectious Diseases Source Type: news

Is It Time to Add Universal CMV Screening for Newborns?
(MedPage Today) -- BOSTON -- The time for universal congenital cytomegalovirus (cCMV) screening may well be here, researchers said. In a study of nearly 24,000 newborns across six hospitals in Minnesota, testing for cCMV using a dried blood... (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - October 13, 2023 Category: American Health Source Type: news

How Many Diphtheria Vaccines are Currently Licensed in the US?
Discussion Diphtheria is caused by the toxin produced by Corynebacterium diphtheriae. Two other Corynebacterium species (C. ulcerans and C. pseudotuberculosis) may produce diphtheria toxin; both species are zoonotic. Diphtheria is spread by respiratory droplets and also contact with open ulcers or sores. Incubation period is 1-10 days with a usual period of 2-5 days. The bacteria attacks the respiratory tract mucosa causing cellular death which in turn causes a “pseudomembrane” of tissue to build up causing respiratory distress and possible death due to airway obstruction (5-10% for general population but up to...
Source: PediatricEducation.org - September 25, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Intimate partner violence is associated with cytomegalovirus among young women in rural South Africa: an HPTN 068 analysis - Kelly NK, G ómez-Olivé FX, Wagner LD, Aiello AE, Kahn K, Pettifor A, Stoner MCD.
ABSTRACTStressful life circumstances (e.g. violence and poverty) have been associated with elevated biomarkers, including C-reactive protein (CRP), cytomegalovirus (CMV), and herpes simplex virus type-1 (HSV-1), among older adults in high-income settings. ... (Source: SafetyLit)
Source: SafetyLit - September 19, 2023 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Drug Trials Snapshot: LIVTENCITY
LIVTENCITY is a prescription medicine used to treat cytomegalovirus (CMV) infection and disease. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - September 14, 2023 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Cytomegalovirus antibodies are associated with mood disorders, suicide, markers of neuroinflammation, and microglia activation in postmortem brain samples - Zheng H, Webster MJ, Weickert CS, Beasley CL, Paulus MP, Yolken RH, Savitz J.
Cytomegalovirus (CMV) is a common, neurotrophic herpesvirus that can be reactivated by inflammation and cause central nervous system disease. We hypothesize that CMV may contribute to the neuroinflammation that underlies some psychiatric disorders by (1) e... (Source: SafetyLit)
Source: SafetyLit - July 3, 2023 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Letermovir Noninferior for CMV Prophylaxis in Kidney Recipients
TUESDAY, June 13, 2023 -- Letermovir is noninferior to valganciclovir for prevention of cytomegalovirus (CMV) among CMV-seronegative kidney transplant recipients who receive an organ from a CMV-seropositive donor, according to a study published... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 13, 2023 Category: Pharmaceuticals Source Type: news

New Antiviral Option for CMV Prophylaxis After Kidney Transplant
(MedPage Today) -- Letermovir (Prevymis) proved noninferior to valganciclovir (Valcyte), the standard of care, in a clinical trial of cytomegalovirus (CMV) prophylaxis in high-risk kidney transplant patients, researchers reported. In a phase III... (Source: MedPage Today Surgery)
Source: MedPage Today Surgery - June 7, 2023 Category: Surgery Source Type: news