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Purification of a 19-kDa pore-forming cytolysin from the sea anemone Heteractis magnificaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Pore-forming cytolysins of 19 kDa from sea anemones present a remarkable cytolytic property. In the present work, a purified 19-kDa cytolysin was obtained from the sea anemone Heteractis magnifica. The purification steps involved ammonium sulfate precipitation and subsequently desalting by dialysis against 10 mM sodium phosphate buffer (pH 7.4), followed by anion exchange chromatography in DEAE-Sepharose® column (GE Healthcare, Sweden) and gel filtration chromatography using Sephadex® G-50 matrix (GE Healthcare, Sweden). The active fractions from the gel filtration chromatography were pooled and rechromatographed in the ...
Source: Journal of Venomous Animals and Toxins including Tropical Diseases - September 8, 2010 Category: Tropical Medicine Source Type: journals

First implantable artificial kidney could remove demand for dialysisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
An artificial kidney that would be implanted inside the body and work as well as a living organ is just around the corner, scientists have revealed. (Source: the Mail online | Health)
Source: the Mail online | Health - September 7, 2010 Category: Consumer Health News Source Type: news

Model For Implantable Artificial Kidney To Replace Dialysis Unveiled By UCSFemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
UCSF researchers have unveiled a prototype model of the first implantable artificial kidney, in a development that one day could eliminate the need for dialysis. The device, which would include thousands of microscopic filters as well as a bioreactor to mimic the metabolic and water-balancing roles of a real kidney, is being developed in a collaborative effort by engineers, biologists and physicians nationwide, led by Shuvo Roy, PhD, in the UCSF Department of Bioengineering and Therapeutic Sciences... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 6, 2010 Category: Consumer Health News Tags: Medical Devices / Diagnostics Source Type: news

CPMC will sell dialysis unit to DaVitaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
California Pacific Medical Center is moving ahead with plans to sell its outpatient dialysis services to DaVita Inc., a huge Denver-based dialysis specialist, for an undisclosed sum. (Source: bizjournals.com Health Care:Health Insurance headlines)
Source: bizjournals.com Health Care:Health Insurance headlines - September 6, 2010 Category: American Health Source Type: journals

CPMC will sell dialysis unit to DaVitaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
California Pacific Medical Center is moving ahead with plans to sell its outpatient dialysis services to DaVita Inc., a huge Denver-based dialysis specialist, for an undisclosed sum. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - September 6, 2010 Category: Biotechnology Source Type: journals

Lower Blood Pressure May Preserve Kidney Function in Some Patients-9/1/10email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Intensively treating hypertension in some African Americans with kidney disease by pushing blood pressure well below the current recommended goal may significantly decrease the number who lose kidney function and require dialysis, suggests a Johns Hopkins-led study publishing in the New England Journal of Medicine Thursday. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - September 4, 2010 Category: Research Source Type: news

Roy unveils model of artificial kidneyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
September 3, 2010 -- The model for a surgically implantable artificial kidney the size of a coffee cup has been unveiled by the national project's lead researcher, Shuvo Roy, PhD, a member of the UCSF Department of Bioengineering and Therapeutic Sciences. The device is intended to give patients with end stage renal disease (ESRD) the health benefits of a kidney transplant while addressing the limited number of donors. Unlike dialysis, which is a short-term treatment for ESRD patients, tethering them to equipment for long periods of time, the new implantable device is being designed as a long-term solution and is a free-sta...
Source: UCSF School of Pharmacy News - September 3, 2010 Category: Universities & Medical Training Source Type: organizations

Three-year extension study of lanthanum carbonate therapy in Japanese hemodialysis patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion  Lanthanum therapy was able to reduce and maintain the serum phosphate level within the K/DOQI and JSDT guideline ranges in Japanese dialysis patients for 3 years. Content Type Journal ArticleDOI 10.1007/s10157-010-0339-3Authors Takashi Shigematsu, Division of Nephrology and Blood Purification Medicine, Department of Medicine, Wakayama Medical University, 881-1 Kimiidera, Wakayama, Wakayama 641-8509, JapanThe Lanthanum Carbonate Research Group Journal Clinical and Experimental NephrologyOnline ISSN 1437-7799Print ISSN 1342-1751 (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - September 3, 2010 Category: Urology & Nephrology Tags: Clinical and Experimental Nephrology Source Type: journals

Model for implantable artificial kidney to replace dialysis unveiledemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Researchers have unveiled a prototype model of the first implantable artificial kidney, in a development that one day could eliminate the need for dialysis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 3, 2010 Category: Science Source Type: news

Occurrence Of Increased Kidney Transplant Listings In Patients With Prior Non-Kidney Transplantsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Individuals who received a non-kidney organ transplant in the past may be more likely to be listed for a kidney transplant prior to initiation of dialysis (pre-emptive listing) than other candidates, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The results indicate that the growth in the numbers of this group of kidney transplant candidates adds to the list of organ allocation challenges. Kidney failure may accompany or complicate transplantation of the liver, heart, or lung... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 3, 2010 Category: Consumer Health News Tags: Transplants / Organ Donations Source Type: news

UCSF Unveils Artificial Kidney to Replace Dialysisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
UCSF researchers today unveiled a prototype model of the first implantable artificial kidney, in a development that one day could eliminate the need for dialysis. (Source: UCSF Medical Center)
Source: UCSF Medical Center - September 3, 2010 Category: Universities & Medical Training Authors: webservices at ucsfhealth.org Source Type: organizations

Effect of hemodialysis and peritoneal dialysis on redox status in chronic renal failure patients: a comparative studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
ObjectiveTo investigate the effects of hemodialysis (HD) and periotoneal dialysis (PD) on oxidative stress in chronic renal failure patients (CRF). Methods: 20 HD patients and 20 PD patients were compared with 20 end stage renal failure patients (CRF). Results: Thiobarbituric acid reactive substances (TBARS) values were elevated in HD and decreased in PD compared to CRF (P (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - September 3, 2010 Category: Lipidology Authors: Khedidja MekkiWarda TalebNassima BouzidiAbbou KaddousMalika Bouchenak Source Type: journals

Plasma osteoprotegerin, arterial stiffness, and mortality in normoalbuminemic Japanese hemodialysis patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions  In long-term normoalbuminemic Japanese hemodialysis patients, with low prevalence of inflammation, OPG levels were strongly linked with both arterial stiffness and worse outcome. Content Type Journal ArticleDOI 10.1007/s00198-010-1377-0Authors A. Nakashima, Department of Advanced Nephrology, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi Minami-Ku, Hiroshima, 734-8551 JapanJ. J. Carrero, Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, SwedenA. R. Qureshi, Divisions of R...
Source: Osteoporosis International - September 2, 2010 Category: Orthopaedics Tags: Osteoporosis International Source Type: journals

Calif. Allows Safety-Net Coverage Cost Increases; Georgia Illegal Immigrant Dialysis Agreement Reachedemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The Los Angeles Times: "As state leaders blast giant health insurers for raising rates, Gov. Arnold Schwarzenegger's administration has quietly allowed hefty increases for thousands of sick or jobless Californians who must rely on expensive safety-net coverage -- if they want insurance at all. To the frustration of policyholders, state regulators have given insurance companies permission to raise maximum premiums for most of the 20,000 Californians who depend on the coverage of last resort... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 2, 2010 Category: Consumer Health News Tags: Health Insurance / Medical Insurance Source Type: news

Will Extra Protein And Exercise Help Dialysis Patients?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
University of Illinois scientists will learn whether protein supplements and cycling during treatments can help dialysis patients fight cardiovascular disease and retain physical function, thanks to a $2.1 million grant from the National Institutes of Health (NIH). "Patients with kidney failure face many health problems... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 2, 2010 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

U.S. Renal Care Builds Its First Dialysis Center In Oklahomaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
U.S. Renal Care, Inc. (USRC), a leading privately-held provider of outpatient dialysis services, today announced it has started construction of a dialysis center in Grove, Oklahoma, the company's first in the state. The center, expected to open in December 2010, will bring the company's patient total to more than 5,500 served across 85 dialysis centers, home and specialty hospital dialysis programs and facilities. The expansion into northeast Oklahoma is part of USRC's commitment to serving rural communities without dialysis or nephrology services... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 2, 2010 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

Lower blood pressure may preserve kidney function in some patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Intensively treating hypertension in some African Americans with kidney disease by pushing blood pressure well below the current recommended goal may significantly decrease the number who lose kidney function and require dialysis, suggests a new study. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 2, 2010 Category: Science Source Type: news

Relationship between major adverse cardiac events and angiographic findings in dialysis patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions  This observational study confirms that in dialysis patients coronary atherosclerotic damage shown by angiography is strongly related to MACE and that age and severe CAD are major risk factors for MACE. Content Type Journal ArticleDOI 10.1007/s11255-010-9821-9Authors F. Fabbian, U.O. di Clinica Medica, Arcispedale S. Anna, Ferrara, ItalyG. Cacici, U.O. di Cardiologia, Policlinico G.B. Rossi, Verona, ItalyV. De Biase, Divisione di Nefrologia, Ospedale Civile Maggiore, Verona, ItalyT. Yabarek, Divisione di Nefrologia, Ospedale Civile Maggiore, Verona, ItalyC. Gangemi, Divisione di Nefrologia...
Source: International Urology and Nephrology - September 2, 2010 Category: Urology & Nephrology Tags: International Urology and Nephrology Source Type: journals

Evaluation of Kidney Transplantation Programmes Using System Simulationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  In the case of kidney transplantations, there is always a serious imbalance between the number of kidneys donated for transplantation and the number of persons wishing to receive a transplant. This not only affects the quality of life of those unable to obtain a transplant, but it also has important repercussions on the treatment of End Stage Renal Disease (ESRD) by transplantation and dialysis. Also there are a number of ways in which the kidney transplantation can be achieved, such as the cadaveric kidney transplantation, live donor kidney transplantation, kidney paired donation and list exchange....
Source: Journal of Medical Systems - September 2, 2010 Category: Information Technology Tags: Journal of Medical Systems Source Type: journals

UCSF unveils model for implantable artificial kidney to replace dialysisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(University of California - San Francisco) UCSF researchers today unveiled a prototype model of the first implantable artificial kidney, in a development that one day could eliminate the need for dialysis. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - September 2, 2010 Category: Biology Source Type: news

Will extra protein and exercise help dialysis patients? U of I profs get $2.1 million to find outemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(University of Illinois College of Agricultural, Consumer and Environmental Sciences) University of Illinois scientists have received a $2.1 million grant from the National Institutes of Health to learn whether protein supplements and cycling during treatments can help dialysis patients fight cardiovascular disease and retain physical function. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 1, 2010 Category: Global & Universal Source Type: news

Deal Would Provide Dialysis to Illegal Immigrants in Atlantaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The deal, if completed, would end a yearlong impasse that has come to symbolize the health care plight of the country’s uninsured immigrants and the hospitals that end up caring for them. (Source: NYT Health)
Source: NYT Health - September 1, 2010 Category: Consumer Health News Authors: By KEVIN SACK and CATRIN EINHORN Tags: Grady Memorial Hospital Medicine and Health dialysis Health Insurance and Managed Care Illegal Immigrants Source Type: news

Deal Would Provide Dialysis to Illegal Immigrants in Atlantaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The deal, if completed, would end a yearlong impasse that has come to symbolize the health care plight of the country’s uninsured immigrants and the hospitals that end up caring for them. (Source: NYT)
Source: NYT - September 1, 2010 Category: American Health Authors: By KEVIN SACK and CATRIN EINHORN Tags: Grady Memorial Hospital Medicine and Health dialysis Health Insurance and Managed Care Illegal Immigrants Source Type: news

Association Between Platelet‐Related Hemostasis Impairment and Functional Iron Deficiency in Hemodialysis Patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - September 1, 2010 Category: Hematology Authors: Irena P ZupanMiso SabovicBarbara SalobirJadranka B PonikvarPeter CernelcJanez LavreBojan Vujkovac Source Type: journals

Peritoneal Dialysis‐Related Peritonitis Caused by Vancomycin‐Resistant Enterococcus faeciumemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - September 1, 2010 Category: Hematology Authors: Aydin UnalCigdem AgkusIsmail KocyigitOktay OymakCengiz Utas Source Type: journals

Review of Helicobacter pylori Infection and Chronic Renal Failureemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - September 1, 2010 Category: Hematology Authors: Mitsushige SugimotoYoshio Yamaoka Source Type: journals

Efficacy of Cytokine Removal by Plasmadiafiltration Using a Selective Plasma Separator: In Vitro Sepsis Modelemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - September 1, 2010 Category: Hematology Authors: Mingxin LiJun XueJunfeng LiuDingwei KuangYong GuShanyan Lin Source Type: journals

Nephrogenic systemic fibrosis, in patients with end stage kidney disease on dialysis, in the greater Auckland region, from 2000 ‐ 2006email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Nephrology)
Source: Nephrology - September 1, 2010 Category: Urology & Nephrology Authors: Jamie C Kendrick‐JonesDavid M VossJanak R De Zoysa Source Type: journals

High Peritoneal Transport Status is Not an Independent Risk Factor for High Mortality in Patients Treated with Automated Peritoneal Dialysis.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We undertook this study to elucidate whether baseline peritoneal membrane transport characteristics are associated with high mortality in incident automated peritoneal dialysis (APD) patients. This retrospective study includes 117 patients who started APD at Yonsei University Health System from 1996 to 2008 and had a PET within 3 months of APD initiation. High transporters were significantly older and had a higher incidence of cardiovascular disease. Patient survival for years 1, 3, and 5 were 85%, 64%, and 35% for high transporter and 94%, 81%, and 68% for non-high transporter group (P<0.01). Multivariate analysis ...
Source: J Korean Med Sci - September 1, 2010 Category: Journals (General) Authors: Chang TI, Park JT, Lee DH, Lee JH, Yoo TH, Kim BS, Kang SW, Lee HY, Choi KH Tags: J Korean Med Sci Source Type: journals

Transcatheter arterial embolization using ethanol in a dialysis patient for contracting enlarged polycystic kidneys.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report a dialysis patient with enlarged polycystic kidneys and poor oral intake due to abdominal distention that was successfully treated by TAE with absolute ethanol. PMID: 20808704 [PubMed - in process] (Source: Korean J Radiol)
Source: Korean J Radiol - September 1, 2010 Category: Radiology Authors: Rim H, Jung GS, Jung YS Tags: Korean J Radiol Source Type: journals

Stem cell technology for the treatment of acute and chronic renal failure.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Acute and chronic renal failure are disorders with high rates of morbidity and mortality. Current treatment is based upon conventional dialysis to provide volume regulation and small solute clearance. There is growing recognition that renal failure is a complex disease state requiring a multifactorial therapy to address the short-comings of the conventional monofactorial approach. Kidney transplantation remains the most effective treatment, however, organ availability lags far behind demand. Many key kidney functions including gluconeogenesis, ammoniagenesis, metabolism of glutathione, catabolism of important peptide h...
Source: Translational Research : the journal of laboratory and clinical medicine - August 31, 2010 Category: Laboratory Medicine Authors: Pino CJ, Humes HD Tags: Transl Res Source Type: journals

New nephrotoxic mushroom discovered in western Michiganemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
3.5 out of 5 stars Ingestion of a newly described North American mushroom species from Michigan resulting in chronic renal failure: Cortinarius orellanosus. Judge BS et al. Clin Toxicol 2010 Jul 8. [Epub ahead of print] Abstract The authors describe the development of chronic renal failure in a 53-year-old woman who ingested mushrooms she had picked herself under an oak tree in western Michigan.  At three days after ingestion she developed gastrointestinal symptoms, and at nine days stopped producing urine.  Serum creatinine was 18.3 mg/dL, and she was admitted to hospital for hemodialysis. A specimen of the mushroom ing...
Source: The Poison Review - August 29, 2010 Category: Toxicology Authors: Leon Tags: Medical amanita smithiana cortinarius orellanossus cortinarius orellanus kidney failure mushroom nephrotoxic Source Type: info

Long-term outcome of nephropathic cystinosis: a 20-year single-center experienceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, our experience shows a significant improvement in the renal and nonrenal complications of cystinosis over the past decades and highlights the importance of early diagnosis in order to initiate cysteamine as soon as possible. Content Type Journal ArticleDOI 10.1007/s00467-010-1641-8Authors Marcella Greco, Department of Nephrology and Urology, Division of Nephrology and Dialysis, Bambino Gesù Children’s Hospital and Research Institute, Piazza S. Onofrio 4, 00165 Rome, ItalyMilena Brugnara, Department of Mother-Child and Biology-Genetics, University of Verona, Verona, ItalyMarco Zaffanello, Departme...
Source: Pediatric Nephrology - August 28, 2010 Category: Urology & Nephrology Tags: Pediatric Nephrology Source Type: journals

Case Report: Eculizumab, Bortezomib and Kidney Paired Donation Facilitate Transplantation of a Highly Sensitized Patient Without Vascular Accessemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this report, we describe the combined use of new agents (bortezomib and eculizumab) and modalities (nontraditional vascular access, splanchnic drainage of graft and domino paired donation) in a patient who would have died without transplantation. (Source: American Journal of Transplantation)
Source: American Journal of Transplantation - August 28, 2010 Category: Transplant Surgery Authors: B. E. LonzeN. N. DagherC. E. SimpkinsJ. E. LockeA. L. SingerD. L. SegevA. A. ZacharyR. A. Montgomery Source Type: journals

Cold Machine Perfusion Versus Static Cold Storage of Kidneys Donated After Cardiac Death: A UK Multicenter Randomized Controlled Trialemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
One third of deceased donor kidneys for transplantation in the UK are donated following cardiac death (DCD). Such kidneys have a high rate of delayed graft function (DGF) following transplantation. We conducted a multicenter, randomized controlled trial to determine whether kidney preservation using cold, pulsatile machine perfusion (MP) was superior to simple cold storage (CS) for DCD kidneys. One kidney from each DCD donor was randomly allocated to CS, the other to MP. A sequential trial design was used with the primary endpoint being DGF, defined as the necessity for dialysis within the first 7 days following transplant...
Source: American Journal of Transplantation - August 28, 2010 Category: Transplant Surgery Authors: C. J. E. WatsonA. C. WellsR. J. RobertsJ. A. AkohP. J. FriendM. AkyolF. R. CalderJ. E. AllenM. N. JonesD. CollettJ. A. Bradley Source Type: journals

Hb Variability Doesn't Predict Mortality in Dialysis (CME/CE)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(MedPage Today) -- Variability in blood hemoglobin levels, associated with the use of erythropoiesis-stimulating agents (ESAs), does not predict mortality in dialysis patients, according to a large European population study. (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - August 27, 2010 Category: Hematology Source Type: news

Sequential change of asymmetric dimethylarginine levels after initiation of peritoneal dialysis in patients with end‐stage renal diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
ABSTRACT (Source: Nephrology)
Source: Nephrology - August 27, 2010 Category: Urology & Nephrology Authors: KWAN‐HYUN LEEHYO‐WOOK GILJONG‐OH YANGEUN‐YOUNG LEESAE‐YONG HONG Source Type: journals

ORIGINAL ARTICLE: Use of cardio‐ankle vascular index in chronic dialysis patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: European Journal of Clinical Investigation)
Source: European Journal of Clinical Investigation - August 27, 2010 Category: Journals (General) Authors: Tsu‐Wang ShenChih‐Hsien WangYu‐Hsien LaiBang‐Gee HsuHung‐Hsiang LiouTe‐Chao Fang Source Type: journals

Molecular epidemiology of a hepatitis C virus epidemic in a haemodialysis unit: outbreak investigation and infection outcome.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The outbreak described should serve as a reminder to HD providers that patients undergoing dialysis are at risk for HCV infection and that HCV may be easily transmitted whenever standard precautions are not strictly applied. (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - August 27, 2010 Category: Infectious Diseases Authors: Simone LaniniIsabella AbbateVincenzo PuroFabrizio SosciaFrancesco AlbertoniWalter BattistiAmilcare RutaMaria CapobianchiGiuseppe Ippolito Source Type: journals

Epicardial Cardiac Rhythm Devices for Dialysis Patients: Minimizing the Risk of Infection and Preserving Central Veins.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract Transvenous leads of cardiac rhythm devices (CRDs) are known to cause central stenosis and are vulnerable to contamination during hemodialysis access-related bacteremia. In this retrospective study, nine consecutive chronic hemodialysis patients with transvenous CRD infection due to dialysis access-related bacteremia and recurrent central stenosis are presented. Four patients with tunneled hemodialysis catheters (TDCs) and three with arteriovenous grafts experienced access-related bacteremia that spread to the transvenous CRD. Two patients required repeated angioplasty procedures (less than 3 months apart) for...
Source: Seminars in Dialysis - August 27, 2010 Category: Urology & Nephrology Authors: Asif A, Carrillo R, Garisto JD, Lopera G, Ladino M, Barakat U, Eid N, Salman L Tags: Semin Dial Source Type: journals

Optimization of biotin-labeling of antibodies using mouse IgG and goat anti-mouse IgG-conjugated fluorescent beads and their application as capture probes on protein chip.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study shows the optimization of biotin labeling to antibodies using mouse IgG. Several parameters of the biotin labeling, including the molar ratio of biotin to antibody, the coupling time and the dialysis time, were studied to optimum conditions. The biotin-tagged mouse IgGs were immobilized on avidin coated PMMA (Polymethyl Methacrylate) plates via a biotin-avidin linkage. The immobilization of the IgG to the chip was quantified using goat anti-mouse IgG bound fluorescent beads. It was found that the binding of the fluorescent beads saturated when a 10-fold or higher molar ratio of biotin to antibody was used. In bi...
Source: Journal of Immunological Methods - August 27, 2010 Category: Allergy & Immunology Authors: Lee JH, Choi HK, Chang JH Tags: J Immunol Methods Source Type: journals

Long-term preserved renal function of a patient with mass-forming granulomatous interstitial nephritis by biopsy-based steroid therapyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  In 2001, a 41-year-old Japanese woman was referred to our hospital because of severe renal dysfunction and fever of unknown origin. On admission, her serum creatinine was 8.7 mg/dL, urine protein was 0.3 g/day, and urine β2-microglobulin was 81,007 μg/day. Computed tomography (CT) scans showed bilateral contracted kidneys with a mass projecting from the lower pole of the right kidney. Biopsy of this lesion revealed interstitial nephritis and a noncaseating granuloma. Because extrarenal organ involvement or laboratory findings specific for sarcoidosis or other primary diseases were no...
Source: Clinical and Experimental Nephrology - August 26, 2010 Category: Urology & Nephrology Tags: Clinical and Experimental Nephrology Source Type: journals

Latest BioTrends Report Provides Comprehensive Market Landscape Of The Dialysis Vascular Access Marketemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This report is based on online survey results from over 150 physicians (general nephrologists, surgeons, interventional radiologists and interventional nephrologists). It provides an in-depth view of the dialysis vascular access market and current practice patterns related to both vascular access placement and maintenance. The report explores the roles of various physicians related to vascular access, reasons for choice of different access options and barriers to fistula use... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 25, 2010 Category: Consumer Health News Tags: Vascular Source Type: news

No survival benefit from early‐start dialysis in a population‐based, inception cohort study of Swedish patients with chronic kidney diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Journal of Internal Medicine)
Source: Journal of Internal Medicine - August 25, 2010 Category: Internal Medicine Authors: Marie EvansGiorgio TettamantiOlof NyrénRino BelloccoCarl Michael ForedCarl‐Gustaf Elinder Source Type: journals

The Lancet: Nephrology is not for normal doctors - it is for exceptionally skilled specialist physiciansemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
From The Lancet:Many doctors may view nephrology as a remarkable kind of intensive care. A patient presents in an acute crisis, close to death. Immediate transfer to the renal team follows, then the magical effects of dialysis, and finally recovery. Nephrology is not for normal doctors. The kidney is for exceptionally skilled specialist physicians.Unlike fish, mammals do not seem to have renal regenerative capacity.The silence of the kidney leads medicine to overlook its importance. This lack of awareness means that immense opportunities to prevent not only renal, but also cardiovascular, diseases are being lost.References...
Source: Clinical Cases and Images - August 25, 2010 Category: Journals (General) Tags: Nephrology Source Type: info

The impact of chronic kidney disease on survival after amputation in persons with diabetes.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Survival after amputation is lower in diabetic patients with CKD, dialysis, and high level amputations. PMID: 20739688 [PubMed - as supplied by publisher] (Source: Diabetes Care)
Source: Diabetes Care - August 25, 2010 Category: Endocrinology Authors: Lavery LA, Hunt NA, Ndip A, Lavery DC, Van Houtum W, Boulton AJ Tags: Diabetes Care Source Type: journals

Creatinine-based GFR predicting equations in renal transplantation: reassessing the tubular secretion effectemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion. Our data do not support the use of a cimetidine-based strategy for the evaluation of renal graft function in the clinic, particularly when the GFR is estimated by the MDRD equation. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - August 24, 2010 Category: Urology & Nephrology Authors: Maillard, N., Mehdi, M., Thibaudin, L., Berthoux, F., Alamartine, E., Mariat, C. Tags: Original Article Source Type: journals

Donor-recipient age matching improves years of graft function in deceased-donor kidney transplantationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion. Donor and recipient age matching is an effective method of organ allocation to improve total graft years. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - August 24, 2010 Category: Urology & Nephrology Authors: Lim, W. H., Chang, S., Chadban, S., Campbell, S., Dent, H., Russ, G. R., McDonald, S. P. Tags: Original Article Source Type: journals

Non-invasive detection of pulmonary hypertension prior to renal transplantation is a predictor of increased risk for early graft dysfunctionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion. Pulmonary HTN detected on non-invasive imaging prior to renal transplantation appears to be an independent predictor of early graft dysfunction among those patients who receive a deceased donor kidney. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - August 24, 2010 Category: Urology & Nephrology Authors: Zlotnick, D. M., Axelrod, D. A., Chobanian, M. C., Friedman, S., Brown, J., Catherwood, E., Costa, S. P. Tags: Original Article Source Type: journals

A 50% reduction in cyclosporine exposure in stable renal transplant recipients: renal function benefitsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion. In renal transplant recipients receiving maintenance therapy without corticosteroids, a minimization strategy using three-point pharmacokinetic sampling to reduce and maintain cyclosporine exposure to 50% of the usual levels is safe and reduces the risk of graft dysfunction. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - August 24, 2010 Category: Urology & Nephrology Authors: Etienne, I., Toupance, O., Benichou, J., Thierry, A., Al Najjar, A., Hurault de Ligny, B., Le Meur, Y., Westeel, P.-F., Marquet, P., Francois, A., Hellot, M.-F., Godin, M. Tags: Original Article Source Type: journals