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Treating Hypertension in Diabetes: the Sooner, the BetterTreating Hypertension in Diabetes: the Sooner, the Better
This study suggests that early control of new-onset hypertension may reduce rates of major cardiovascular events in patients with diabetes. Medscape Diabetes & Endocrinology
Source: Medscape Today Headlines - March 4, 2013 Category: Consumer Health News Tags: Diabetes & endocrinology Viewpoint Source Type: news

Self-management Experiences in Type 2 Diabetes MellitusSelf-management Experiences in Type 2 Diabetes Mellitus
Is there a difference in the way men and women approach the challenges of diabetes self-management? BMC Family Practice
Source: Medscape Today Headlines - March 3, 2013 Category: Consumer Health News Tags: Diabetes & endocrinology Journal Article Source Type: news

Biology of lake sturgeon (Acipenser fulvescens) spawning below a dam on the Richelieu River, Quebec: behaviour, egg deposition, and endocrinology
Canadian Journal of Zoology, Volume 0, Issue 0, Page 175-186, e-First articles.
Source: Canadian Journal of Zoology - March 2, 2013 Category: Zoology Tags: article Source Type: research

Stop Sitting, Move More, to Avoid DiabetesStop Sitting, Move More, to Avoid Diabetes
Sedentary behavior may be an even more important risk factor for diabetes than failure to exercise regularly, but the 2 should be considered separately and both addressed, say researchers. Medscape Medical News
Source: Medscape Today Headlines - March 1, 2013 Category: Consumer Health News Tags: Diabetes & endocrinology News Source Type: news

Cancer doesn't change young girls' desire to have children, study shows (Science Daily, 1 March 2013)
A study published in Journal of Adolescent Health compares the results of a 10-statement survey assessing teenage girls' hopes and feelings about reproduction between healthy girls and those given a diagnosis of cancer. Full article
Source: Society for Endocrinology - March 1, 2013 Category: Endocrinology Source Type: news

Regional Clinical Cases 2013 Newport call for cases - deadline 11 March 2013
The Society for Endocrinology is delighted to invite the submission of cases for the next Regional Clinical Cases meeting in association with Welsh Endocrine and Diabetes Society, to be held at Manor House, Celtic Manor, Newport, South Waleson 16 May 2013. To submit your case to present at the meeting and put yourself in contention for one of the six prizes awarded at the meeting please visit the meeting website where you can also view the programme. The deadline for cases is 11 March 2013.
Source: Society for Endocrinology - March 1, 2013 Category: Endocrinology Source Type: news

Age-associated changes in hypothalamic-pituitary-testicular function in middle-aged and older men are modified by weight change and lifestyle factors: longitudinal results from the European Male Ageing Study.
CONCLUSIONS: Body weight and lifestyle factors influence HPT axis function in ageing. Weight loss was associated with a rise, and weight gain a fall, in testosterone, FT and SHBG. Weight management appears to be important in maintaining circulating testosterone in ageing men, and obesity-associated changes in HPT axis hormones are reversible following weight reduction. PMID: 23425925 [PubMed - in process]
Source: European Journal of Endocrinology - March 1, 2013 Category: Endocrinology Authors: Camacho EM, Huhtaniemi IT, O'Neill TW, Finn JD, Pye SR, Lee DM, Tajar A, Bartfai G, Boonen S, Casanueva FF, Forti G, Giwercman A, Han TS, Kula K, Keevil B, Lean ME, Pendleton N, Punab M, Vanderschueren D, Wu FC, EMAS Group Tags: Eur J Endocrinol Source Type: research

Serum selenium is low in newly diagnosed Graves′disease. A population based study
ConclusionPatients with newly diagnosed GD and AIH had significantly lower s‐Se compared with random controls. Our observation supports the postulated link between inadequate selenium supply and overt autoimmune thyroid disease, especially GD.© 2013 Blackwell Publishing Ltd
Source: Clinical Endocrinology - March 1, 2013 Category: Endocrinology Authors: I Bülow Pedersen, N Knudsen, A Carlé, L Schomburg, J Köhrle, T Jørgensen, L Rasmussen, L Ovesen, P Laurberg Tags: Original Article Source Type: research

Combination of a GnRH agonist with an antagonist prevents flare-up effects and protects primordial ovarian follicles in the rat ovary from cisplatin-induced toxicity: a controlled experimental animal study
Conclusions: The combination of a GnRH agonist with antagonist completely prevented the flare-up effect and enhanced the protective effect of the ovary from cisplatin-induced gonadotoxicity in rats.
Source: Reproductive Biology and Endocrinology - March 1, 2013 Category: Endocrinology Authors: Xiaoyan LiXiang KangQingchun DengJing CaiZehua Wang Source Type: research

Cross-talk between skeletal muscle and immune cells: muscle-derived mediators and metabolic implications
Skeletal muscles contain resident immune cell populations and their abundance and type is altered in inflammatory myopathies, endotoxemia or different types of muscle injury/insult. Within tissues, monocytes differentiate into macrophages and polarize to acquire pro- or anti-inflammatory phenotypes. Skeletal muscle macrophages play a fundamental role in repair and pathogen clearance. These events require a precisely regulated cross-talk between myofibers and immune cells, involving paracrine/autocrine and contact interactions. Skeletal muscle also undergoes continuous repair as a result of contractile activity that involve...
Source: AJP: Endocrinology and Metabolism - March 1, 2013 Category: Endocrinology Authors: Pillon, N. J., Bilan, P. J., Fink, L. N., Klip, A. Tags: Reviews Source Type: research

Inflammation during obesity is not all bad: evidence from animal and human studies
Chronic inflammation is a characteristic of obesity and is associated with accompanying insulin resistance, a hallmark of type 2 diabetes mellitus (T2DM). Although proinflammatory cytokines are known for their detrimental effects on adipose tissue function and insulin sensitivity, their beneficial effects in the regulation of metabolism have not drawn sufficient attention. In obesity, inflammation is initiated by a local hypoxia to augment angiogenesis and improve adipose tissue blood supply. A growing body of evidence suggests that macrophages and proinflammatory cytokines are essential for adipose remodeling and adipocyt...
Source: AJP: Endocrinology and Metabolism - March 1, 2013 Category: Endocrinology Authors: Ye, J., McGuinness, O. P. Tags: Reviews Source Type: research

Chronic levothyroxine and acute T3 treatments enhance the amplitude and time course of uterine contractions in human
This study compares the functional consequences of levothyroxine (T4) treatment during pregnancy as well as the acute affects of triiodothyronine (T3) on spontaneous uterine contractile activities observed in vitro. Uterine biopsies were obtained from consenting women undergoing elective caesarean at term (n = 28). Spontaneous contractile activities from T4-treated pregnant women (n = 8) were compared with control patients (n = 20) by isometric tension measurements. Effects of acute T3 and T4 on control tissues were also monitored. Area under the curve, amplitude, time to peak, duration, and frequency were quantified. In u...
Source: AJP: Endocrinology and Metabolism - March 1, 2013 Category: Endocrinology Authors: Corriveau, S., Pasquier, J.-C., Blouin, S., Bellabarba, D., Rousseau, E. Tags: Articles Source Type: research

Metabolic programming effects initiated in the suckling period predisposing for adult-onset obesity cannot be reversed by calorie restriction
In this study, calorie restriction by pair-feeding was imposed on HC male rats (HC/PF) to normalize food intake similar to that of mother-fed (MF) rats from weaning until postnatal day 140. A group of HC/PF rats was switched over to ad libitum feeding (HC/PF/AL) from days 90 to 140. Pair-feeding reduced body weight gains and serum insulin and leptin levels in HC/PF rats compared with HC rats, but these parameters were restored to HC levels in the HC/PF/AL rats after ad libitum feeding. Interestingly, the heightened insulin secretory response of isolated islets from adult HC/PF and HC/PF/ AL rats to glucose, acetylcholine, ...
Source: AJP: Endocrinology and Metabolism - March 1, 2013 Category: Endocrinology Authors: Srinivasan, M., Mahmood, S., Patel, M. S. Tags: Articles Source Type: research

Skeletal muscle uncoupling-induced longevity in mice is linked to increased substrate metabolism and induction of the endogenous antioxidant defense system
Ectopic expression of uncoupling protein 1 (UCP1) in skeletal muscle (SM) mitochondria increases lifespan considerably in high-fat diet-fed UCP1 Tg mice compared with wild types (WT). To clarify the underlying mechanisms, we investigated substrate metabolism as well as oxidative stress damage and antioxidant defense in SM of low-fat- and high-fat-fed mice. Tg mice showed an increased protein expression of phosphorylated AMP-activated protein kinase, markers of lipid turnover (p-ACC, FAT/CD36), and an increased SM ex vivo fatty acid oxidation. Surprisingly, UCP1 Tg mice showed elevated lipid peroxidative protein modificatio...
Source: AJP: Endocrinology and Metabolism - March 1, 2013 Category: Endocrinology Authors: Keipert, S., Ost, M., Chadt, A., Voigt, A., Ayala, V., Portero-Otin, M., Pamplona, R., Al-Hasani, H., Klaus, S. Tags: Articles Source Type: research

{beta}-Adrenergic signaling stimulates osteoclastogenesis via reactive oxygen species
Sympathetic signaling regulates bone resorption through receptor activator of nuclear factor-B ligand (RANKL) expression via the β-adrenergic receptor (β-AR) on osteoblasts. Reactive oxygen species (ROS) are known as one type of osteoclast regulatory molecule. Here we show that an antioxidant, α-lipoic acid (α-LA), treatment prevent the β-adrenergic signaling-induced bone loss by suppressing osteoclastogenesis, and sympathetic signaling directly regulates osteoclastogenesis through β2-AR expressed on osteoclasts via intracellular ROS generation. In an in vitro study, the β-AR agonist is...
Source: AJP: Endocrinology and Metabolism - March 1, 2013 Category: Endocrinology Authors: Kondo, H., Takeuchi, S., Togari, A. Tags: Articles Source Type: research

Reductions in insulin concentrations and {beta}-cell mass precede growth restriction in sheep fetuses with placental insufficiency
In pregnancy complicated by placental insufficiency (PI) and intrauterine growth restriction (IUGR), the fetus near term has reduced basal and glucose-stimulated insulin concentrations and reduced β-cell mass. To determine whether suppression of insulin concentrations and β-cell mass precedes reductions in fetal weight, which would implicate insulin deficiency as a cause of subsequent IUGR, we measured basal and glucose-stimulated insulin concentrations and pancreatic histology at 0.7 gestation in PI fetuses. Placental weights in the PI pregnancies were 40% lower than controls (265 ± 26 vs. 442 ± 41...
Source: AJP: Endocrinology and Metabolism - March 1, 2013 Category: Endocrinology Authors: Limesand, S. W., Rozance, P. J., Macko, A. R., Anderson, M. J., Kelly, A. C., Hay, W. W. Tags: Articles Source Type: research

Estimating the risk after gestational diabetes mellitus: can we improve the information from the postpartum OGTT?
Risk stratification after pregnancy with gestational diabetes mellitus (GDM) is based on screening with the 2-h oral glucose tolerance test (OGTT). Actually, prediabetes and diabetes are diagnosed by impaired fasting [fasting plasma glucose (FPG)] and 120 min-postload glucose levels (120'-PLG). We hypothesized that the clinical information could be improved by including measurements at different time points from the OGTT in the medical decision-making process. One hundred ten women with previous gestational diabetes (pGDM) and 41 controls were included 3–6 mo after delivery and underwent specific metabolic assessment...
Source: AJP: Endocrinology and Metabolism - March 1, 2013 Category: Endocrinology Authors: Gobl, C. S., Bozkurt, L., Prikoszovich, T., Tura, A., Pacini, G., Kautzky-Willer, A. Tags: Articles Source Type: research

Disruption of claudin-18 diminishes ovariectomy-induced bone loss in mice
Claudin-18 (Cldn-18), a member of the tight junction family of proteins, is a negative regulator of RANKL-induced osteoclast differentiation and bone resorption (BR) in vivo. Since estrogen deficiency decreases bone mass in part by a RANKL-mediated increase in BR, we evaluated whether estrogen regulates Cldn-18 expression in bone. We found that Cldn-18 expression was reduced in the bones of estrogen deficient mice, whereas it was increased by estrogen treatment in osteoblasts and osteoclasts in vitro. We next evaluated the role of Cldn-18 in mediating estrogen-induced bone loss. Cldn-18 knockout (KO) and littermate wild-ty...
Source: AJP: Endocrinology and Metabolism - March 1, 2013 Category: Endocrinology Authors: Kim, H.-Y., Alarcon, C., Pourteymour, S., Wergedal, J. E., Mohan, S. Tags: Articles Source Type: research

Losartan increases muscle insulin delivery and rescues insulin's metabolic action during lipid infusion via microvascular recruitment
Insulin delivery and transendothelial insulin transport are two discrete steps that limit muscle insulin action. Angiotensin II type 1 receptor (AT1R) blockade recruits microvasculature and increases glucose use in muscle. Increased muscle microvascular perfusion is associated with increased muscle delivery and action of insulin. To examine the effect of acute AT1R blockade on muscle insulin uptake and action, rats were studied after an overnight fast to examine the effects of losartan on muscle insulin uptake (protocol 1), microvascular perfusion (protocol 2), and insulin's microvascular and metabolic actions in the state...
Source: AJP: Endocrinology and Metabolism - March 1, 2013 Category: Endocrinology Authors: Wang, N., Chai, W., Zhao, L., Tao, L., Cao, W., Liu, Z. Tags: Articles Source Type: research

High dickkopf-1 levels in sera and leukocytes from children with 21-hydroxylase deficiency on chronic glucocorticoid treatment
In this study, we enrolled 18 patients (9 females) and 18 sex- and age-matched controls. We found in 21-OHD patients high serum and leukocyte levels of dickkopf-1 (DKK1), a secreted antagonist of the Wnt/β-catenin signaling pathway known to be a key regulator of bone mass. In particular, we demonstrated by flow cytometry, confocal microscopy, and real-time PCR that monocytes, T lymphocytes, and neutrophils from patients expressed high levels of DKK1, which may be related to the cGC therapy. In fact, we showed that dexamethasone treatment markedly induced the expression of DKK1 in a dose- and time-dependent manner in l...
Source: AJP: Endocrinology and Metabolism - March 1, 2013 Category: Endocrinology Authors: Brunetti, G., Faienza, M. F., Piacente, L., Ventura, A., Oranger, A., Carbone, C., Benedetto, A. D., Colaianni, G., Gigante, M., Mori, G., Gesualdo, L., Colucci, S., Cavallo, L., Grano, M. Tags: Articles Source Type: research

Corrigendum
Source: AJP: Endocrinology and Metabolism - March 1, 2013 Category: Endocrinology Tags: Corrigendum Source Type: research

Cardiometabolic Risk Factors Among US Adolescents and Young Adults and Risk of Early Mortality
CONCLUSIONS: Our finding that risk for death before age 55 among US adolescents and young adults was associated with central obesity, smoking, and hyperglycemia supports reducing the prevalence of these risk factors among younger US residents.
Source: PEDIATRICS - March 1, 2013 Category: Pediatrics Authors: Saydah, S., Bullard, K. M., Imperatore, G., Geiss, L., Gregg, E. W. Tags: endocrinology Article Source Type: research

Development of Obesity-Associated Secondary HypogonadismDevelopment of Obesity-Associated Secondary Hypogonadism
Learn about the complex inter-relationships between obesity, T2DM, sleep disorders, and hypogonadism in men. Clinical Endocrinology
Source: Medscape Today Headlines - February 28, 2013 Category: Consumer Health News Tags: Diabetes & endocrinology Journal Article Source Type: news

Modeling Diabetes Care: The FREEDOM EffectModeling Diabetes Care: The FREEDOM Effect
The FREEDOM trial not only changed thinking on angioplasty vs CABG for patients with diabetes and heart disease, but also supported better systems in managing these patients. Medscape Cardiology
Source: Medscape Today Headlines - February 28, 2013 Category: Consumer Health News Tags: Diabetes & endocrinology Article Source Type: news

Artificial Pancreas Reduces Overnight Hypoglycemia at CampArtificial Pancreas Reduces Overnight Hypoglycemia at Camp
A short-term crossover trial of an artificial pancreas compared with an insulin pump in 54 children with type 1 diabetes is first in real-world setting. Medscape Medical News
Source: Medscape Today Headlines - February 28, 2013 Category: Consumer Health News Tags: Diabetes & endocrinology News Source Type: news

Gastric Bypass Puts Type 2 Diabetes Into RemissionGastric Bypass Puts Type 2 Diabetes Into Remission
Two-year follow-up of the STAMPEDE study shows gastric bypass induces remission in moderately obese patients with type 2 diabetes and as such is a viable therapeutic option, say researchers. Medscape Medical News
Source: Medscape Today Headlines - February 28, 2013 Category: Consumer Health News Tags: Diabetes & endocrinology News Source Type: news

How estrogens prevent from lipid-induced insulin resistance.
PMID: 23429711 [PubMed - in process]
Source: Endocrinology - February 28, 2013 Category: Endocrinology Authors: Jelenik T, Roden M Tags: endocrinology Source Type: research

Immunosuppressive biological mechanisms support reassessment of use of the injectable contraceptive medroxyprogesterone acetate.
PMID: 23429710 [PubMed - in process]
Source: Endocrinology - February 28, 2013 Category: Endocrinology Authors: Hapgood JP Tags: endocrinology Source Type: research

Learning and stress: hormone Homer prevents stress-induced cognitive deficits (Science Daily, 27 February 2013)
A study from Germany published in Journal of Neuroscience investigates mechanisms behind stress-induced cognitive impairments in a mouse model of social stress. Full article
Source: Society for Endocrinology - February 28, 2013 Category: Endocrinology Source Type: news

Cell sugar concentrations affect hyaluronan production and cancer growth (EurekAlert, 27 February 2013)
A study from Finland published in Journal of Biological Chemistry investigates the relationship between cellular sugar and the development of cancer. Full article
Source: Society for Endocrinology - February 28, 2013 Category: Endocrinology Source Type: news

Quantity of sugar in food supply linked to diabetes rates, Stanford researcher says (EurekAlert, 27 February 2013)
A US study published in PLoS ONE examines data on sugar availability and diabetes rates from 175 countries over the past decade. Full article
Source: Society for Endocrinology - February 28, 2013 Category: Endocrinology Source Type: news

Research With Worms Links Insulin To Learning
Recent work by Harvard researchers demonstrates how the signaling pathway of insulin and insulinlike peptides plays a critical role in helping to regulate learning and memory. The research, led by Yun Zhang, associate professor of organismic and evolutionary biology, is described in a Feb. 6 paper in Neuron. "People think of insulin and diabetes, but many metabolic syndromes are associated with some types of cognitive defects and behavioral disorders, like depression or dementia," Zhang said...
Source: Health News from Medical News Today - February 28, 2013 Category: Consumer Health News Tags: endocrinology Source Type: news

Increased Prolactin Concentrations in a Patient with Bipolar Disorder [Clinical Case Study]
Source: Clinical Chemistry - February 28, 2013 Category: Chemistry Authors: Schmidt, M., Sofronescu, A., Short, B., Nahas, Z., Zhu, Y. Tags: endocrinology and Metabolism Clinical Case Study Source Type: research

Commentary [Commentaries]
Source: Clinical Chemistry - February 28, 2013 Category: Chemistry Authors: Irwig, M. S. Tags: endocrinology and Metabolism Commentaries Source Type: research

Quantification of Globotriaosylsphingosine in Plasma and Urine of Fabry Patients by Stable Isotope Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry [Endocrinology and Metabolism]
CONCLUSIONS: This assay for the quantification of lysoGb3 and lyso-ene-Gb3 in human plasma and urine samples will be an important tool in the diagnosis of Fabry disease and for monitoring the effect of enzyme replacement therapy in patients with Fabry disease.
Source: Clinical Chemistry - February 28, 2013 Category: Chemistry Authors: Gold, H., Mirzaian, M., Dekker, N., Joao Ferraz, M., Lugtenburg, J., Codee, J. D. C., van der Marel, G. A., Overkleeft, H. S., Linthorst, G. E., Groener, J. E. M., Aerts, J. M., Poorthuis, B. J. H. M. Tags: Lipids, Lipoproteins, and Cardiovascular Risk Factors endocrinology and Metabolism Source Type: research

Prospective Evaluation of B-type Natriuretic Peptide Concentrations and the Risk of Type 2 Diabetes in Women [Endocrinology and Metabolism]
CONCLUSIONS: NT-proBNP concentrations that are high, but still within the reference interval, associate with reduced risk of incident diabetes in women and support a favorable role for natriuretic peptides in the prevention of T2DM.
Source: Clinical Chemistry - February 28, 2013 Category: Chemistry Authors: Everett, B. M., Cook, N. R., Chasman, D. I., Magnone, M. C., Bobadilla, M., Rifai, N., Ridker, P. M., Pradhan, A. D. Tags: endocrinology and Metabolism Source Type: research

Disparate Hemoglobin Results [What Is Your Guess?]
Source: Clinical Chemistry - February 28, 2013 Category: Chemistry Authors: Gooden, C. E., Winkler, A. M., Fantz, C. R. Tags: endocrinology and Metabolism What Is Your Guess? Source Type: research

Prevalence and Predictors of Vitamin D Deficiency in AdultsPrevalence and Predictors of Vitamin D Deficiency in Adults
Black and Asian patients may be at risk of vitamin D deficiency. Endocrine Practice
Source: Medscape Today Headlines - February 27, 2013 Category: Consumer Health News Tags: Diabetes & endocrinology Journal Article Source Type: news

Increased Dietary Sugar Drives Global Rise in DiabetesIncreased Dietary Sugar Drives Global Rise in Diabetes
Independent of obesity or other factors, the availability of sugary foods and drinks explains some of the worldwide differences in prevalence of type 2 diabetes, researchers report. Medscape Medical News
Source: Medscape Today Headlines - February 27, 2013 Category: Consumer Health News Tags: Diabetes & endocrinology News Source Type: news

Screening for CAH Will Save Girls' Lives, TooScreening for CAH Will Save Girls' Lives, Too
Screening of newborns for congenital adrenal hyperplasia will save more lives than previously thought because it also picks up females with the condition, new research shows. Medscape Medical News
Source: Medscape Today Headlines - February 27, 2013 Category: Consumer Health News Tags: Diabetes & endocrinology News Source Type: news

FDA Suspends Pediatric Clinical Trials After Report Of Death
Sensipar (Cinacalcet Hydrochloride): Drug Safety Communication - FDA Suspends Pediatric Clinical Trials After Report Of Death AUDIENCE: Health Professional, Endocrinology, Pediatrics ISSUE: FDA has stopped all pediatric clinical trials of...
Source: Drugs.com - Pharma News - February 27, 2013 Category: Pharmaceuticals Source Type: news

Pigs in space
No abstract available
Source: Cardiovascular Endocrinology - February 26, 2013 Category: Cardiology Tags: Viewpoint Source Type: research

Diabetic myonecrosis: a diagnosis to be considered
Diabetic myonecrosis is an under-recognized complication of long-standing poorly controlled diabetes mellitus usually involving the quadriceps muscle. The disease is self-limited with an excellent short-term prognosis but unfortunately a poor long-term prognosis because of macrovascular events. Herein, we present a case of diabetic myonecrosis and discuss the pathophysiology, presentation, diagnosis, and management of the disease. Physicians should maintain a high index of suspicion for this rare clinical entity in diabetic patients presenting with acute muscle pain.
Source: Cardiovascular Endocrinology - February 26, 2013 Category: Cardiology Tags: Short report Source Type: research

Association of thyroid stimulating hormone levels with subclinical carotid atherosclerosis in a Mediterranean female population
Conclusion: In a cohort of women, higher TSH levels were associated with subclinical atherosclerotic changes of the carotid artery wall.
Source: Cardiovascular Endocrinology - February 26, 2013 Category: Cardiology Tags: Original articles Source Type: research

The association between hemoglobin A1C values and deep sternal wound infections in diabetes patients undergoing cardiac surgery
Conclusion: In cardiac surgery patients with DM, despite standardized control of immediate postoperative hyperglycemia, a high preoperative A1C was associated with an increased incidence of DSWI.
Source: Cardiovascular Endocrinology - February 26, 2013 Category: Cardiology Tags: Original articles Source Type: research

From ‘Bad Pharma’ to better guidance?
No abstract available
Source: Cardiovascular Endocrinology - February 26, 2013 Category: Cardiology Tags: Editorial Source Type: research

Cinacalcet Trials Halted Due to Pediatric DeathCinacalcet Trials Halted Due to Pediatric Death
The studies were attempting to determine whether the calcium-lowering drug approved for adults also was safe and effective in treating children. News Alerts
Source: Medscape Today Headlines - February 26, 2013 Category: Consumer Health News Tags: Diabetes & endocrinology News Alert Source Type: news

EU Rejects Obesity Drug Qsiva for the Second TimeEU Rejects Obesity Drug Qsiva for the Second Time
Despite an appeal by Vivus, the European Medicines Agency has rejected the obesity treatment phentermine/topiramate extended release for the second time. Any benefit "does not outweigh the risks," says the EMA. Medscape Medical News
Source: Medscape Today Headlines - February 26, 2013 Category: Consumer Health News Tags: Diabetes & endocrinology News Source Type: news

Extremely high estrogen levels may underlie complications of single-birth IVF pregnancies (EurekAlert, 25 February 2013)
A paper in Fertility and Sterility further investigates associations between oestrogen levels and outcomes in fresh vs frozen embryo IVF procedures. Full article
Source: Society for Endocrinology - February 26, 2013 Category: Endocrinology Source Type: news