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ICT fails to accelerate drug approvalsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Inderscience Publishers) Drug approvals are taking just as long as they ever did despite increased expenditure on new information technology at the Food and drug Administration. So says a statistical analysis of approval intervals from 1997 to 2006, published in the International Journal of Electronic Healthcare. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 19, 2009 Category: Global & Universal Source Type: news

Obesity is a sign – over-eating is a symptom: an aetiological framework for the assessment and management of obesityemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Obesity is characterized by the accumulation of excess body fat and can be conceptualized as the physical manifestation of chronic energy excess. Using the analogy of oedema, the consequence of positive fluid balance or fluid retention, obesity can be seen as the consequence of positive energy balance or calorie 'retention'. Just as the assessment of oedema requires a comprehensive assessment of factors related to fluid balance, the assessment of obesity requires a systematic assessment of factors potentially affecting energy intake, metabolism and expenditure. Rather than just identifying and describing a behaviour ('this...
Source: Obesity Reviews - November 18, 2009 Category: Eating Disorders and Weight Management Authors: A. M. Sharma, R. Padwal Source Type: journals

Playing Active Video Games Can Equal Moderate-intensity Exerciseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Active Wii sports™ video games and some Wii fit™ activities may increase adults' energy expenditure as much as moderately intense exercise, according to research presented at the American Heart Association's Scientific Sessions 2009. The study, funded by Nintendo™, demonstrated that about one-third of the virtual physical activities require an energy expenditure of 3. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 17, 2009 Category: Consumer Health News Tags: IT / Internet / E-mail Source Type: news

Playing Active Video Games Can Equal Moderate-intensity Exerciseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Active Wii sports™ video games and some Wii fit™ activities may increase adults' energy expenditure as much as moderately intense exercise, according to research presented at the American Heart Association's Scientific Sessions 2009. The study, funded by Nintendo™, demonstrated that about one-third of the virtual physical activities require an energy expenditure of 3.0 METs or above, considered moderate-intensity exercise. (Source: Obesity / Weight Loss / Fitness News From Medical News Today)
Source: Obesity / Weight Loss / Fitness News From Medical News Today - November 17, 2009 Category: Eating Disorders and Weight Management Tags: IT / Internet / E-mail Source Type: news

Impaired Oxidative Metabolism and Inflammation are Associated with Insulin Resistance in ER{alpha} Deficient Mice.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Impaired estrogen action is associated with the metabolic syndrome in humans. We sought to determine if impaired estrogen action in female C57Bl6 mice, produced by whole body ESR1 ablation, could recapitulate aspects of this syndrome including inflammation, insulin resistance, and obesity. Indeed we find that global knockout (KO) of the estrogen receptor (ER)alpha leads to reduced oxygen uptake and caloric expenditure compared to wildtype (WT) mice. In addition, fasting insulin, leptin, and PAI-1 levels were markedly elevated while adiponectin levels were reduced in normal chow-fed KO. Furthermore, ERalpha KO mice exhi...
Source: American Journal of Physiology. Endocrinology and Metabolism - November 17, 2009 Category: Physiology Authors: Ribas V, Nguyen MT, Henstridge DC, Nguyen AK, Beaven SW, Watt MJ, Hevener AL Tags: Am J Physiol Endocrinol Metab Source Type: journals

Playing active video games can equal moderate intensity exerciseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(American Heart Association) One-third of Wii sport and Wii fit activities provide energy expenditures equal to moderate-intensity exercise. Active video games may help prevent or improve obesity and lifestyle-related diseases, researchers said. The study was funded by Nintendo. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 16, 2009 Category: Global & Universal Source Type: news

Can playing active video games equal moderate intensity exercise?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
One-third of Wii sport and Wii fit activities provide energy expenditures equal to moderate-intensity exercise. Active video games may help prevent or improve obesity and lifestyle-related diseases, researchers said. The study was funded by Nintendo. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 16, 2009 Category: Science Source Type: news

How Much Should One Spend on An Engagement Ring?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A common norm regarding how much a man should spend on an engagement ring is three months of his annual salary. One reason for placing such a heavy financial burden on this particular courtship ritual is that it serves as an honest signal of a man's commitment to his prospective wife. In other words, pretenders need not apply.Clearly though, in the same way that people do not always leave 15% of their bill as a tip (even though this is the norm) but rather adjust it up or down as a function of other factors (e.g., service quality), one would expect that the price paid for an engagement ring might too be linked to several e...
Source: Psychology Today Relationships Center - November 15, 2009 Category: Psychiatry & Psychology Authors: Gad Saad, Ph.D. Tags: Evolutionary Psychology Gender Relationships Sex annual salary average incomes bria bridewealth cost of ring courtship ritual descriptive statistics engagement rings exact issue extraneous variables g service lee cronk marr Source Type: consumer

Ph.D. Thesis Support Grant Related to the History of Pharmacyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The American Institute of the History of Pharmacy wishes to encourage academic research within its scope. Therefore it offers a grant-in-aid totaling $2,000 or more annually to a graduate student to reinforce historical investigations of some aspect of pharmacy, whether ancient or modern, to pay research expenses not normally met by the university granting the degree. Any thesis project devoted to the history of pharmacy, history of drugs, or other humanistic study utilizing a pharmaco-historical approach, is eligible if based in an institution of higher learning of the USA. Applications postmarked by February 1 will be e...
Source: ScanGrants feed - November 15, 2009 Category: Research Authors: American Institute of the History of Pharmacy Source Type: funding

Health Care Accounts For Eight Percent Of US Carbon Footprint, Calculation Findsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The American health-care sector accounts for 8 percent of the country's carbon dioxide emissions, according to a first-of-its-kind calculation of health care's carbon footprint. Researchers used expenditures from different parts of the health care sector to measure the industry's potential effect upon global warming through the release of carbon dioxide and other greenhouse gases. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 14, 2009 Category: Science Source Type: news

Comparative study of visitors to CAM practitioners in USA and Norwayemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Question: USA and Norway are among the countries that have highest total expenditure on health per capita and also high utilization of complementary and alternative medicine (CAM). But they have fundamentally different health care systems. The aim was therefore to compare the profile characteristics of adults who have visited a CAM practitioner the last year in the USA and Norway.Methods: Data from the National Health Interview Survey (NHIS) in USA from 2002 and the Level of Living Survey (LOLS) in Norway from 2002 were used. Both surveys were nationally representative household surveys of the non-institutionalized civilia...
Source: European Journal of Integrative Medicine - November 13, 2009 Category: Complementary Medicine Authors: A. Steinsbekk, M.B. Rise, M. Ackin Source Type: journals

Remodeling of skeletal muscle microvasculature in sickle cell trait and {alpha}-thalassemia.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The influence of sickle cell trait and/or alpha-thalassemia on skeletal muscle microvascular network characteristics was assessed and compared to control subjects (HbAA) in 30 Cameroonian residents (10 HbAA, 5 HbAAalpha-t, 6 HbAS and 9 HbASalpha-t) matched for maximal work capacity and daily energy expenditure. Subjects performed an incremental exercise to exhaustion and underwent a muscle biopsy. Muscle fiber type and surface area were not different among groups. However, sickle cell trait (SCT) was associated with lower capillary density (P < 0.05), lower capillary tortuosity (P < 0.001), and enlarged microvess...
Source: American Journal of Physiology. Heart and Circulatory Physiology - November 13, 2009 Category: Physiology Authors: Vincent L, Féasson L, Oyono-Enguéllé S, Banimbeck V, Denis C, Guarneri C, Aufradet E, Monchanin G, Martin C, Gozal D, Dohbobga M, Wouassi D, Garet M, Thiriet P, Messonnier LA Tags: Am J Physiol Heart Circ Physiol Source Type: journals

The Effect of Community Health Centers on Healthcare Spending & Utilizationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A report summarizing studies comparing health care expenditures finds Community Health Centers (CHCs) reduce utilization and spending for other, costlier types of care, including emergency room and inpatient hospital care. -- National Association of Community Health Centers (Source: Rural publications via the Rural Assistance Center)
Source: Rural publications via the Rural Assistance Center - November 12, 2009 Category: Rural Health Source Type: info

Is the prevalence of asthma declining? Systematic review of epidemiological studiesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Asthma prevalence has increased very considerably in recent decades such that it is now one of the commonest chronic disorders in the world. Recent evidence from epidemiological studies, however, suggests that the prevalence of asthma may now be declining in many parts of the world, which, if true is important for health service planning and also because this offers the possibility of generating and testing new aetiological hypotheses. Our objective was to determine whether the prevalence of asthma is declining worldwide. We undertook a systematic search of EMBASE, Medline, Web of Science and Google Scholar, for high quali...
Source: Allergy - November 12, 2009 Category: Allergy & Immunology Authors: C. Anandan, U. Nurmatov, O. C. P. van Schayck, A. Sheikh Source Type: journals

Impact of 6-month Caloric Restriction on Autonomic Nervous System Activity in Healthy, Overweight, Individuals.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Caloric restriction (CR) increases maximum lifespan but the mechanisms are unclear. Dominance of the sympathetic nervous system (SNS) over the parasympathetic nervous system (PNS) has been shown to be a strong risk factor for cardiovascular disease. Obesity and aging are associated with increased SNS activity, and weight loss and/or exercise seem to have positive effects on this balance. We therefore evaluated the effect of different approaches of CR on autonomic function in 28 overweight individuals participating in the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE) trial. Partic...
Source: Obesity - November 12, 2009 Category: Eating Disorders and Weight Management Authors: de Jonge L, Moreira EA, Martin CK, Ravussin E, Tags: Obesity (Silver Spring) Source Type: journals

Walnut Consumption Increases Satiation but Has No Effect on Insulin Resistance or the Metabolic Profile Over a 4-day Period.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Obesity and diabetes have been associated with increased consumption of highly processed foods, and reduced consumption of whole grains and nuts. It has been proposed, mainly on the basis of observational studies, that nuts may provide superior satiation, may lead to reduced calorie consumption, and may decrease the risk of type 2 diabetes; but evidence from randomized, interventional studies is lacking. A total of 20 men and women with the metabolic syndrome participated in a randomized, double-blind, crossover study of walnut consumption. Subjects had two 4-day admissions to the clinical research center where they we...
Source: Obesity - November 12, 2009 Category: Eating Disorders and Weight Management Authors: Brennan AM, Sweeney LL, Liu X, Mantzoros CS Tags: Obesity (Silver Spring) Source Type: journals

Analysis Underscores Financial Burden of Mental Illness on Criminal Justice and Health Care Systems(Nov 11, 2009)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Philadelphia, PA (November 11, 2009) – Results from a large, retrospective analysis of inmates with a serious mental illness (SMI) underscores the financial burden of mental illness on the criminal justice and health and human services (HHS) systems, and may provide useful information to policy makers. The results of the analysis, which evaluated patterns of arrest, utilization of services, and corresponding expenditures among nearly 3,800 inmates in a large urban county of Florida, were presented this week at the 137th (Source: Johnson and Johnson)
Source: Johnson and Johnson - November 11, 2009 Category: Pharmaceuticals Source Type: organizations

American Heart Association National Fellow to Faculty Transition Award Programemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Application Deadline: Jan. 22, 2010 (11:59 p.m. CT) Award Activation: July 1, 2010The method for applying for funding is Web-based, via our electronic system, Grants@Heart. With this new system, the applicant fills out the online application using Internet Explorer or Safari browsers. Important: * Begin your application early to allow all parties time to complete the process. * The applicant must submit the completed application to the grants officer selected in the application. It is the applicant's responsibility to contact the grants officer and/or monitor the status of his/her own application. * The grants office...
Source: ScanGrants feed - November 10, 2009 Category: Research Authors: American Heart Association Source Type: funding

Increasing Diversity in Nicotine and Tobacco Research: Travel Scholarship to the 2010 Society for Research on Nicotine and Tobacco Annual Meetingemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Society for Research on Nicotine and Tobacco2010 SRNT Annual MeetingFebruary 24-27, 2010Hilton Baltimore HotelBaltimore, Marylandhttp://www.srnt.org/meeting/2010/index.html___________________________________________________________________BackgroundThe 2004 Institute of Medicine Report, In the Nation’s Compelling Interest: Ensuring Diversity in the Health Care Workforce, clearly states that although the diversity of the United States is rapidly increasing, many minority racial/ethnic groups are under-represented in the health professions. Increasing diversity, particularly among researchers, may help to enhance the ...
Source: ScanGrants feed - November 10, 2009 Category: Research Authors: Tobacco-Related Health Disparities Committee of the Society for Research on Nicotine and Tobacco Source Type: funding

Effects of GH in human muscle and fatemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Skeletal muscle is the major constituent of lean body mass and a major determinant of energy expenditure both at rest and during physical activity. Growth hormone, in turn, influences muscle mass as well as energy expenditure. Growth hormone substitution in adults increases muscle mass by 5–10%, but part of the effect is attributed to rehydration rather than protein accretion. In addition, GH regulates substrate metabolism in muscle and in particular antagonizes insulin-stimulated glucose disposal. This effect is linked to increased free fatty acid (FFA) flux but the molecular mechanisms remain un...
Source: Pediatric Nephrology - November 9, 2009 Category: Urology & Nephrology Tags: Pediatric Nephrology Source Type: journals

Lifestyle Choices Vs. Life Expectancy: Carnegie Mellon Researchers Link Health-Care Debate To Risk Of Dying In US And Europeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The current health care debate in the United States is complicated. Trade-offs between heath care expenditures, lifestyle choices and life expectancy have been suggested but seldom clearly demonstrated. The U.S. spends on average more than $45,000 per year on health care for every 80 year old, while the Europeans spend $12,000 for the same age group. U.S. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 9, 2009 Category: Consumer Health News Tags: Health Insurance / Medical Insurance Source Type: news

Lifestyle Choices Vs. Life Expectancy: Carnegie Mellon Researchers Link Health-Care Debate To Risk Of Dying In US And Europeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The current health care debate in the United States is complicated. Trade-offs between heath care expenditures, lifestyle choices and life expectancy have been suggested but seldom clearly demonstrated. The U.S. spends on average more than $45,000 per year on health care for every 80 year old, while the Europeans spend $12,000 for the same age group. U.S. octogenarians have a 20 percent less chance of dying than Europeans in the next year. But, more than 30 percent of the U.S. (Source: Cancer / Oncology News From Medical News Today)
Source: Cancer / Oncology News From Medical News Today - November 9, 2009 Category: Cancer & Oncology Tags: Health Insurance / Medical Insurance Source Type: news

United Negro College Fund/Merck Postdoctoral Science Research Fellowshipemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The United Negro College Fund and the Merck Research Laboratories announce the availability of theUNCF•Merck Postdoctoral Science Research Fellowships. These fellowships are a component of the UNCF•Merck Science Initiative, the goal of which is to support the training and development of world-class African American biomedical research scientists. At least 10 UNCF•Merck Postdoctoral Science Research Fellowships will be awarded per year. The competition is open to all applicants who meet the eligibility criteria. Award recipients are selected based on the applicants’ abilities and accomplishments. PURPO...
Source: ScanGrants feed - November 9, 2009 Category: Research Authors: United Negro College Fund/Merck Source Type: funding

United Negro College Fund/Merck Graduate Science Research Dissertation Fellowshipsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The United Negro College Fund and the Merck Institute for Science Education announce the availability of theUNCF•Merck Graduate Science Research Dissertation Fellowships. These fellowships are a component of the UNCF•Merck Science Initiative, the goal of which is to support the training and development of world-class African American biomedical scientists. At least 12 UNCF•Merck Graduate Science Research Dissertation Fellowship awards will be made per year. The competition is open to all applicants who meet the eligibility criteria. Award recipients are selected based on the applicants’abilities and a...
Source: ScanGrants feed - November 9, 2009 Category: Research Authors: United Negro College Fund/Merck Source Type: funding

Surgical Infection Society Junior Faculty Fellowship Awardemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
For Junior FacultyFaculty members in the rank of Assistant Professor or Instructor for no more than three years in a surgical discipline are eligible to apply for the SIS Junior Faculty Fellowship Award. The amount of this award is $50,000/year.The total amount of other extramural grants-in-aid supporting the Junior Faculty awardee’s research cannot exceed $30,000 (US). There are no specific restrictions on the amount of intramural (departmental/institutional) support. If there are any questions regarding these restrictions, the applicant or their sponsor should call or email Craig M. Coopersmith, MD, Chair of the S...
Source: ScanGrants feed - November 8, 2009 Category: Research Authors: Surgical Infection Society Source Type: funding

Surgical Infection Society/Wyeth Evaluative Research Fellowship Awardemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The SIS/Wyeth Evaluative Research Fellowship Award only supports projects dealing with the broad area of evaluative research in surgical infection. Residents or fellows who have completed at least two years of post-graduate training in a surgical discipline are eligible to apply for the SIS/Wyeth Evaluative Research Fellowship Award. (Please note that this fellowship will only be awarded as funds are available.)Research proposals should pertain to the broad area of evaluative research in surgical infection. Typical topics might include: 1. Clinical epidemiology (factors affecting the incidence of surgical infections, mor...
Source: ScanGrants feed - November 8, 2009 Category: Research Authors: Surgical Infection Society/Wyeth Source Type: funding

Infant Rotavirus Vaccine Reduced Diarrhea-Related Hospitalizations, ED Visits, and Outpatient Visitsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The pentavalent rotavirus vaccine is safe and effective and greatly reduces resource use and expenditures related to diarrheal illness in infants younger than 1 year of age. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 7, 2009 Category: Consumer Health News Tags: Infectious Diseases Source Type: news

Infant Rotavirus Vaccine Reduces Diarrhea-Related Hospitalizations, ED Visits, and Outpatient Visitsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The pentavalent rotavirus vaccine is safe and effective and greatly reduces resource use and expenditures related to diarrheal illness in infants younger than 1 year of age. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 7, 2009 Category: Consumer Health News Tags: Infectious Diseases Source Type: news

The medical management of urinary incontinence.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Urinary incontinence is the involuntary leakage of urine; it affects millions of people worldwide, causing significant detrimental effects on their quality of life. Direct expenses, such as containment products, long-term drug prescriptions and surgery, complemented by indirect costs, such as reduced employment productivity, result in overall expenditure running to billions of dollars. Stress urinary incontinence (SUI) occurs on physical exertion, and results from weakness of the bladder outlet. Urgency urinary incontinence (UUI) results from inability to resist a sudden compelling desire to pass urine, arising as a co...
Source: Autonomic Neuroscience - November 7, 2009 Category: Neuroscience Authors: Shaban A, Drake MJ, Hashim H Tags: Auton Neurosci Source Type: journals

School resources, resource allocation, and risk of physical assault against Minnesota educators.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
To investigate the relation between schools' resource levels (i.e., annual per student expenditures), school resource allocations, and physical assault (PA) against Minnesota's educators, a study was conducted from the two-phase Minnesota Educators' Study (MES) that incorporated school-level fiscal and demographic data from the Minnesota Department of Education (MDE). The MES examined a randomly selected cohort of employed, state-licensed kindergarten through grade 12 educators. From mailed questionnaires, response rates for both Phase I (comprehensive data collection on violent events) and Phase II (case-control) were...
Source: Accident; Analysis and Prevention. - November 6, 2009 Category: Occupational Health Authors: Sage SK, Gerberich SG, Ryan AD, Nachreiner NM, Church TR, Alexander BH, Mongin SJ Tags: Accid Anal Prev Source Type: journals

World Diabetes Day - 14 November (Ways You Can Cover The UN Day In Your Country And Globally)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
According to latest data released by the International Diabetes Federation (IDF), diabetes now affects 285 million people worldwide costs the world economy at least US$376 billion in 2010, or 11.6% of total world healthcare expenditure. A further 344 million are at risk of developing diabetes (pre-diabetes). (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 6, 2009 Category: Consumer Health News Tags: Diabetes Source Type: news

World Diabetes Day - 14 November (Ways You Can Cover The UN Day In Your Country And Globally)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
According to latest data released by the International Diabetes Federation (IDF), diabetes now affects 285 million people worldwide costs the world economy at least US$376 billion in 2010, or 11.6% of total world healthcare expenditure. A further 344 million are at risk of developing diabetes (pre-diabetes). If nothing is done to reverse the epidemic, IDF predicts that by 2030, 435 million people will live with the disease as at a cost projected to exceed US$490 billion. (Source: Diabetes News From Medical News Today)
Source: Diabetes News From Medical News Today - November 6, 2009 Category: Endocrinology Tags: Diabetes Source Type: news

Energy Gap Useful Tool For Successful Weight Loss Maintenance Strategyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Americans continue to get heavier. Most weight control methods short of bariatric surgery are generally considered ineffective in preventing obesity or reducing weight. The term energy gap was coined to estimate the change in energy balance (intake and expenditure) behaviors required to achieve and sustain reduced body weight outcomes in individuals and populations. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 5, 2009 Category: Consumer Health News Tags: Obesity / Weight Loss / Fitness Source Type: news

Energy Gap Useful Tool For Successful Weight Loss Maintenance Strategyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Americans continue to get heavier. Most weight control methods short of bariatric surgery are generally considered ineffective in preventing obesity or reducing weight. The term energy gap was coined to estimate the change in energy balance (intake and expenditure) behaviors required to achieve and sustain reduced body weight outcomes in individuals and populations. (Source: Obesity / Weight Loss / Fitness News From Medical News Today)
Source: Obesity / Weight Loss / Fitness News From Medical News Today - November 5, 2009 Category: Eating Disorders and Weight Management Tags: Obesity / Weight Loss / Fitness Source Type: news

Effects of a Popular Exercise and Weight Loss Program on Weight Loss, Body Composition, Energy Expenditure and Health in Obese Womenemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study puts the popular fitness and weight loss program Curves to the test and tests the impact of altering the ratio of carbohydrate and protein in hypoenergetic diet. Nutrition and Metabolism (Source: Medscape Ob/Gyn & Women's Health Headlines)
Source: Medscape Ob/Gyn & Women's Health Headlines - November 4, 2009 Category: OBGYN Tags: Pathology & Lab Medicine Source Type: info

Energy gap useful tool for successful weight loss maintenance strategyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Elsevier Health Sciences) The term energy gap was coined to estimate the change in energy balance (intake and expenditure) behaviors required to achieve and sustain reduced body weight outcomes in individuals and populations. In a commentary published in the November 2009 issue of the Journal of the American Dietetic Association, researchers more precisely clarify the concept of the energy gap (or energy gaps) and discuss how the concept can be properly used as a tool to help understand and address obesity. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 4, 2009 Category: Global & Universal Source Type: news

Obesity Society Grants Program Covidien Research Grantsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Focus of research proposals: Applications are solicited in one of the following two focus areas: Childhood Obesity - Prevention and/or Treatment The epidemic of childhood overweight and obesity mandates study in the prevention and treatment of this disorder. Basic, clinical and population research studies are solicited to address the prevention and/or treatment of childhood obesity. Pilot/Feasibility research and/or planning grants for future clinical research studies are accepted. Weight Gain After Bariatric Surgery The recognized problem of weight regain following weight loss in patients treated with gastric banding, sl...
Source: ScanGrants feed - November 4, 2009 Category: Research Authors: Obesity Society Source Type: funding

Effects of experimental weight perturbation on skeletal muscle work efficiency, fuel utilization, and biochemistry in human subjects.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Maintenance of a body weight 10% above or below that "customary" for lean or obese individuals results in respective increases or decreases in the energy expended in low levels of physical activity (non-resting energy expenditure, NREE). These changes are greater than can be accounted for by the altered body weight or composition, and are due mainly to altered skeletal muscle work efficiency at low levels of power generation. We performed biochemical analysis of vastus lateralis muscle needle biopsy samples to determine whether maintenance of an altered body weight was associated with changes in skeletal muscle histomo...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - November 4, 2009 Category: Physiology Authors: Goldsmith RL, Joanisse DR, Gallagher D, Pavlovich KH, Shamoon EL, Leibel RL, Rosenbaum M Tags: Am J Physiol Regul Integr Comp Physiol Source Type: journals

Metabolic Demands of Rock Climbing in Transfemoral Amputeesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Int J Sports MedDOI: 10.1055/s-0029-1239562AbstractThis pilot study compared the energy expenditure required to climb an indoor rock wall, in amputees utilizing five prosthetic configurations. Three experienced climbers (1M age 21 yr, 2F ages 30 and 49 yr) with unilateral transfemoral amputation climbed a 9.14 m indoor rock wall, 5.9 Yosemite Decimal Scale rating, using the following prosthetic configurations: 1. no prosthesis; 2. stubby prosthesis-foot forward; 3. stubby prosthesis-foot backward; 4. articulated prosthesis-knee unlocked; 5. articulated prosthesis-knee locked. Subjects climbed three times with each co...
Source: International Journal of Sports Medicine - November 3, 2009 Category: Sports Medicine Tags: Training & Testing Source Type: journals

Quantifying the mechanical work of resting quadriceps muscle toneemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report a study of the mechanics of resting quadriceps muscle in adult surgical patients that determines how much metabolic activity can be attributed to quadriceps resting-muscle mechanical work. This was calculated by studying the motion of relaxed supine subjects’ instrumented legs dropped onto a pillow before and after anesthesia with muscle paralysis. By subtracting the acceleration of the dropping leg of the conscious subject before the quadriceps is paralysed from that found after paralysis, resting muscle tensile force and power of the quadriceps muscles can be calculated. Mechanomyography was also recorded...
Source: European Journal of Applied Physiology - November 3, 2009 Category: Physiology Tags: European Journal of Applied Physiology Source Type: journals

Implications of the global financial crisis for the response to diseases of poverty within overall health sector development: the case of tuberculosisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The global financial crisis poses a threat to global health, and may exacerbate diseases of poverty, e.g. HIV, malaria and tuberculosis. Exploring the implications of the global financial crisis for the health sector response to tuberculosis is useful to illustrate the practical problems and propose possible solutions. The response to tuberculosis is considered in the context of health sector development. Problems and solutions are considered in five key areas: financing, prioritization, government regulation, integration and decentralization. Securing health gains in global tuberculosis control depends on protecting expen...
Source: Tropical Medicine and International Health - November 3, 2009 Category: Tropical Medicine Authors: Dermot Maher Source Type: journals

Central actions of orexin-A on hypothalamic paraventricular nucleus activity in conscious, freely moving ratsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We showed that intracerebroventricular (icv) administration of orexins increases arterial blood pressure (ABP), heart rate (HR), and sympathetic outflow in conscious rats. Orexins have been reported to be important mediators in several physiological functions such as feeding behavior, energy expenditure, and the awake–sleep cycle. To examine the possible effects of orexins on the neural activity of the paraventricular nucleus (PVN) of the hypothalamus, an integrative center of the autonomic and endocrine functions related to intero- and exteroceptive stress responses, we simultaneously recorded ABP, HR, and single-unit a...
Source: Autonomic Neuroscience: Basic and Clinical - November 2, 2009 Category: Neuroscience Authors: Nan-Shou Yu, Takato Kunitake, Hiroshi Kannan Tags: Abstracts: The Japanese Autonomic Nervous System Source Type: journals

A Selection Of Recent Studies And Surveysemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study examines patterns of uninsurance for low-income working-age adults with chronic health conditions or disabilities, as documented in the Medical Expenditure Panel Survey (MEPS). The authors report "two large and growing gaps in public insurance programs. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 2, 2009 Category: Consumer Health News Tags: Health Insurance / Medical Insurance Source Type: news

Max4Health hand hygiene evaluation reportemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This report sets out the results of an evaluation of the Max4Health hand hygiene campaign undertaken at Southampton University Hospitals NHS Trust over a nine week period between February and April 2009.   There was no evidence, either from the Trust's auditing tool, or from information on expenditure on soap and hand gel, of any significant effect on hand hygiene compliance that might be attributed to the Campaign. Levels of hand hygiene compliance were very high prior to the introduction of the Campaign; whether it would have an effect in circumstances where hand hygiene compliance is less good might merit furth...
Source: NeLM - News - November 2, 2009 Category: Drugs & Pharmacology Source Type: organizations

DksA and ppGpp directly regulate transcription of the Escherichia coli flagellar cascadeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report here that the activities of promoters at all three levels of the cascade are much higher in strains lacking dksA, resulting in overproduction of flagellin and hyperflagellated cells. In vitro, DksA/ppGpp inhibits the flhDC promoter and the [sigma]70-dependent fliA promoter transcribing the gene for [sigma]28. However, DksA and ppGpp do not affect the [sigma]28-dependent fliA promoter or the [sigma]28-dependent fliC promoter in vitro, suggesting that the dramatic effects on expression of those genes in vivo are mediated indirectly through direct effects of DksA/ppGpp on FlhDC and [sigma]28 expression. We conclude ...
Source: Molecular Microbiology - November 2, 2009 Category: Microbiology Authors: Justin J. Lemke, Tim Durfee, Richard L. Gourse Source Type: journals

Chewing Gum Can Reduce Calorie Intake, Increase Energy Expenditure, Nutritionist Findsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A nutrition professor studying the effects of chewing sugar-free gum on weight management has found that it can help to reduce calorie intake and increase energy expenditure. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 1, 2009 Category: Science Source Type: news

People From Ohio And Georgia Pay Less For Dental Care Than The National Averageemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The annual amount spent by Georgians and Ohioans or their insurers for dental care in 2006 averaged about $150 less than the national average of $607, according to the latest News and Numbers from the Agency for Healthcare Research and Quality. The average annual dental expenditure for each Georgian who had dental care was $466, while for Ohioans, it was $474. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 1, 2009 Category: Consumer Health News Tags: Dentistry Source Type: news

Nutrition, work performance, and cognitionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Many working dogs face the challenge of maintaining performance over time, with a particular emphasis on physical and cognitive performance. Knowledge of the very different physiological bases that govern short, intense effort versus that of longer yet lower-intensity exertion, and of the biological levers that govern the interplay of qualities as diverse as strength, resistance, endurance, speed, motivation, mental focus, and proprioception, now permits a more precise definition of the biological keys for optimum working performance in the dog. This success is based on 4 factors: genetic selection, motivation, specific ph...
Source: Journal of Veterinary Behavior: Clinical Applications and Research - November 1, 2009 Category: Veterinary Research Authors: Sarah Rivière Tags: Abstracts Source Type: journals

Physiologic Responses of Firefighter Recruits During a Supervised Live-Fire Work Performance Testemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Del Sal, M, Barbieri, E, Garbati, P, Sisti, D, Rocchi, MBL, and Stocchi, V. Physiologic responses of firefighter recruits during a supervised live-fire work performance test. J Strength Cond Res 23(8): 2396-2404, 2009-The aim of this research was to determine physiologic responses to typical activities of military Italian firefighters. Heart rate (HR), metabolic equivalent units (MET), skin temperature ( T.Sk.), and galvanic skin response (GSR) were measured in 13 firefighters (age = 36.3 +/- 6.9 yr; period of military fire service = 16.8 +/- 7 yr) during the acclimation phase (5 min standing, still dressed in their protec...
Source: Journal of Strength and Conditioning Research - November 1, 2009 Category: Sports Medicine Tags: Original Research Source Type: journals

KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
xF6;p MH, Lewis RE Kinase suppressors of Ras 1 and 2 (KSR1 and KSR2) function as molecular scaffolds to potently regulate the MAP kinases ERK1/2 and affect multiple cell fates. Here we show that KSR2 interacts with and modulates the activity of AMPK. KSR2 regulates AMPK-dependent glucose uptake and fatty acid oxidation in mouse embryonic fibroblasts and glycolysis in a neuronal cell line. Disruption of KSR2 in vivo impairs AMPK-regulated processes affecting fatty acid oxidation and thermogenesis to cause obesity. Despite their increased adiposity, ksr2(-/-) mice are hypophagic and hyperactive but expend less energy tha...
Source: Cell Metabolism - November 1, 2009 Category: Cytology Authors: Costanzo-Garvey DL, Pfluger PT, Dougherty MK, Stock JL, Boehm M, Chaika O, Fernandez MR, Fisher K, Kortum RL, Hong EG, Jun JY, Ko HJ, Schreiner A, Volle DJ, Treece T, Swift AL, Winer M, Chen D, Wu M, Leon LR, Shaw AS, McNeish J, Kim JK, Morrison DK, Tsch& Tags: Cell Metab Source Type: journals