Dual-drug treatment offers hope to children with rare brain cancer
Scientists make ‘promising’ breakthrough on fast-growing DIPG type of tumourScientists have successfully combined two existing cancer drugs to create a treatment for children diagnosed with deadly brain tumours.Diffuse intrinsic pontine glioma (DIPG), a rare and fast-growing type of brain tumour in children, can mutate and evolve to resist treatment with a single drug. There is currently no cure and many children found to have the disease die within months.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - November 5, 2021 Category: Science Authors: Andrew Gregory Health editor Tags: Medical research Cancer Children's health UK news Science Source Type: news
Novel Virus Targeting Deadly Brain Tumors Shows Early Promise Novel Virus Targeting Deadly Brain Tumors Shows Early Promise
Early evidence suggests that an oncolytic virus engineered to kill malignant gliomas may improve survival.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 22, 2021 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
Upstate Foundation awards $50,000 for brain cancer research
Funding supports research program to develop novel treatments for patients with malignant gliomas, the most aggressive form of brain cancer (Source: SUNY Upstate Medical)
Source: SUNY Upstate Medical - September 1, 2021 Category: Universities & Medical Training Tags: News Source Type: news
The promoting effect of traumatic brain injury on the incidence and progression of glioma: a review of clinical and experimental research - Lan YL, Zhu Y, Chen G, Zhang J.
The role of traumatic brain injury in the development of glioma is highly controversial since first presented. This is not unexpected because traumatic brain injuries are overwhelmingly more common than glioma. However, the causes of post-traumatic glioma ... (Source: SafetyLit)
Source: SafetyLit - August 13, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
MRI, histopathologic features boost glioma survival prediction accuracy
Combining MRI and digital histopathologic imaging features boosts the accurac...Read more on AuntMinnie.comRelated Reading:
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Blue Earth study reports Axumin can aid glioma diagnosis (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - July 27, 2021 Category: Radiology Source Type: news
Oncotarget: TERT and its binding protein: overexpression of GABPA/B in gliomas
(Impact Journals LLC) This Oncotarget study confirms the upregulation of TERT in primary glioblastomas while all GABP proteins rise with the malignancy of the gliomas. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 26, 2021 Category: Cancer & Oncology Source Type: news
Geneticists reveal how mutation causes childhood cancer; use drug to reverse its effects
(Trinity College Dublin) Geneticists from Trinity College Dublin have discovered how a specific genetic mutation (H3K27M) causes a devastating, incurable childhood cancer, known as diffuse midline glioma (DMG), and - in lab studies working with model cell types - successfully reverse its effects to slow cancer cell growth with a targeted drug. Their landmark work - just published in leading international journal, Nature Genetics - translates crucial new understanding of the genetics of DMG progression into a highly promising, targeted therapeutic approach and offers significant hope of improved treatments in the future. (S...
Source: EurekAlert! - Cancer - July 22, 2021 Category: Cancer & Oncology Source Type: news
Consumer Health: Understanding glioblastoma
Glioblastoma Awareness Day will be observed on Wednesday, July 21, which makes this a good time to learn more about one of the most complex, deadly and treatment-resistant cancers. Glioblastoma, a type of glioma, is an aggressive cancer that can occur in the brain or spinal cord. It can occur at any age, but it tends to occur more often in older adults. Approximately 13,000 people in the U.S. will be diagnosed with glioblastoma in… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - July 21, 2021 Category: Databases & Libraries Source Type: news
Sleeper cells: Newly discovered stem cell resting phase could put brain tumors to sleep
(Arizona State University) Arizona State University biomedical engineering researchers developed a new cell classifier tool that takes a higher-resolution look at the life cycle of neuroepithelial stem cells, which led to the discovery and exploration of a new resting phase called Neural G0. This knowledge could help scientists to better understand glioma brain tumors and develop new methods of treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 25, 2021 Category: International Medicine & Public Health Source Type: news
MRI shows gadolinium-based contrast elimination is greater after sleep
Brain MRI shows that gadolinium-based contrast clears from patients' glymphati...Read more on AuntMinnie.comRelated Reading:
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Gadolinium in gliomas, adjacent tissue raises questions
MRI shows side sleeping may prevent neurological disease (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - June 23, 2021 Category: Radiology Source Type: news
' Remarkable' Results for Targeted Therapy of Rare CNS Tumors'Remarkable' Results for Targeted Therapy of Rare CNS Tumors
The results come from three small studies of targeted therapy for papillary craniopharyngiomas (PCPs), gliomas and neuroblastomas.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 16, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
POT1 gene mutation predisposes to glioma and affects survival in a sex-specific manner
(Baylor College of Medicine) Researchers have discovered that POT1, a gene known to be associated with risk of glioma, the most common type of malignant brain tumor, mediates its effects in a sex-specific manner. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 19, 2021 Category: International Medicine & Public Health Source Type: news
Australian researchers find new way to target deadly childhood cancer
(Children's Cancer Institute Australia) Research by Australian scientists could pave the way to a new treatment for a currently incurable brain cancer in children called Diffuse Intrinsic Pontine Glioma, or DIPG. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 14, 2021 Category: Cancer & Oncology Source Type: news
Deadly Brain Tumor: Survival Extended by Oncolytic Virus Product Deadly Brain Tumor: Survival Extended by Oncolytic Virus Product
Improved survival was seen in a small trial in which a genetically engineered version of herpes simplex virus was infused directly into high-grade gliomas.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - April 12, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
MD Anderson researchers highlight advances in clinical studies at the AACR Annual Meeting 2021
(University of Texas M. D. Anderson Cancer Center) Researchers at The University of Texas MD Anderson Cancer Center conducted early phase clinical trials that showed promising results for patients with RET fusion-positive cancers, high-grade and low-grade glioma and ovarian cancer. The results for these studies will be presented at the AACR Annual Meeting 2021. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 11, 2021 Category: Cancer & Oncology Source Type: news