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This page shows you the latest news and research items in this category.

The Future of Insomnia Treatment—the Challenge of Implementation
(Source: Sleep)
Source: Sleep - March 1, 2013 Category: Sleep Medicine Source Type: research

Functional Impairment in Adult Sleepwalkers: A Case-Control Study
Conclusion:Adult sleepwalking is a potentially serious condition that may induce violent behaviors, self-injury or injury to bed partners, sleep disruption, excessive daytime sleepiness, fatigue, and psychological distress, all of which affect health-related quality of life.Citation:Lopez R; Jaussent I; Scholz S; Bayard S; Montplaisir J; Dauvilliers Y. Functional impairment in adult sleepwalkers: a case-control study. SLEEP 2013;36(3):345-351. (Source: Sleep)
Source: Sleep - March 1, 2013 Category: Sleep Medicine Source Type: research

Randomized Controlled Trial of Telephone-Delivered Cognitive Behavioral Therapy for Chronic Insomnia
Conclusions:The findings provide preliminary support for telephone-delivered CBTI in the treatment of chronic insomnia. Future larger-scale studies with more diverse samples are warranted. Some individuals with insomnia may also benefit from pamphlet-delivered CBTI with brief telephone support.Citation:Arnedt JT; Cuddihy L; Swanson LM; Pickett S; Aikens J; Chervin RD. Randomized controlled trial of telephone-delivered cognitive behavioral therapy for chronic insomnia. SLEEP 2013;36(3):353-362. (Source: Sleep)
Source: Sleep - March 1, 2013 Category: Sleep Medicine Source Type: research

Longitudinal Course of Depression Scores with and without Insomnia in Non-Depressed Individuals: A 6-Year Follow-Up Longitudinal Study in a Korean Cohort
Conclusions:Persistent insomnia significantly increases the rate in which depression occurs over time in non-depressed individuals, which ultimately leads to higher risk for depression. Additionally, having persistent insomnia also increased the risk of suicidal ideation.Citation:Suh S; Kim H; Yang HC; Cho ER; Lee SK; Shin C. Longitudinal course of depression scores with and without insomnia in non-depressed individuals: a 6-year follow-up longitudinal study in a Korean cohort. SLEEP 2013;36(3):369-376. (Source: Sleep)
Source: Sleep - March 1, 2013 Category: Sleep Medicine Source Type: research

One-Year Course and Effects of Insomnia in Rural Chinese Adolescents
Conclusions:Insomnia has considerable incidence and persistence rates in Chinese adolescents. We have identified several risk factors for the incidence and persistence of insomnia. There are bidirectional associations of insomnia with depression and anxiety but not sleepiness.Citation:Luo C; Zhang J; Pan J. One-year course and effects of insomnia in rural Chinese adolescents. SLEEP 2013;36(3):377-384. (Source: Sleep)
Source: Sleep - March 1, 2013 Category: Sleep Medicine Source Type: research

How to overcome insomnia without prescription drugs
Are the worries of life keeping you up at night? Do you have trouble unwinding at the end of the day, and end up staring at the television or ceiling for hours trying to fall asleep? If getting normal rest is troublesome for you, there is hope apart from having to pop... (Source: NaturalNews.com)
Source: NaturalNews.com - March 1, 2013 Category: Consumer Health Advice Source Type: news

Health Tip: Develop Good Sleep Habits
To wake refreshed each morning Source: HealthDay Related MedlinePlus Pages: Insomnia, Sleep Disorders (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - February 28, 2013 Category: Consumer Health News Source Type: news

Exploring Effective Core Drug Patterns in Primary Insomnia Treatment with Chinese Herbal Medicine: Study Protocol for a Randomized Controlled Trial
This study aims to screen the effective core drug patterns in primary insomnia treatment of three prestigious Chinese clinicians. Methods: A triple-blind, randomized, placebo-controlled, parallel-group clinical trial will be performed. Three clinicians will diagnose and treat every eligible patient individually and independently, producing three prescriptions from three clinicians for every patient. Patients will equally be randomized to one of four groups -- medical group A, medical group B, medical group C, or placebo group -- and observed for efficacy of treatment. The sample will include primary insomnia patients meeti...
Source: Trials - February 28, 2013 Category: Journals (General) Authors: Shiyan YanRunshun ZhangXuezhong ZhouPeng LiLiyun HeBaoyan Liu Source Type: research

Infographic: Sleepless in America
The infographic below from termlifeinsurance.org does a nice job of summarizing the many problems associated with not getting enough sleep. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - February 26, 2013 Category: Pharmaceuticals Authors: David DiSalvo Source Type: news

Lack Of Sleep Alters Genes
Just one week of abnormal, insufficient sleep is enough to dramatically alter the activity of human genes, according to a new study published by the Proceedings of the National Academy of Sciences. The research, conducted at the University of Surrey, England, has revealed that insufficient sleep - less than six hours a night - affects the activity of over 700 of our genes. These genes are associated with controlling response to stress, immunity, and inflammation... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 26, 2013 Category: Consumer Health News Tags: Sleep / Sleep Disorders / Insomnia Source Type: news

Lack Of Sleep Can Make Our Genes Less Active
Just one week of abnormal, insufficient sleep is enough to dramatically alter the activity of human genes, according to a new study published by the Proceedings of the National Academy of Sciences. The research, conducted at the University of Surrey, England, has revealed that insufficient sleep - less than six hours a night - affects the activity of over 700 of our genes. These genes are associated with controlling response to stress, immunity, and inflammation... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 26, 2013 Category: Consumer Health News Tags: Sleep / Sleep Disorders / Insomnia Source Type: news

Step into the Twilight Zone: Day 25, or A Walk Through Santiago's Witching Hour
"The witching hour, someone had once whispered to her, was a special moment in the middle of the night when every child and every grown-up was in a deep deep sleep, and all the dark things came out from hiding and had the world all to themselves." Roald Dahl, "The BFG," about five minutes before the protagonist is kidnapped by a giant. As a kid I was obsessed with this idea of a witching hour, a time when, I imagined, every person living in my town, everyone I'd ever met and everyone they'd ever met, would be simultaneously asleep. I drove myself into paroxysms of insomnia trying to make it to that magic moment when I wou...
Source: Scientific American - Official RSS Feed - February 26, 2013 Category: Science Tags: Health,Space,Mind & Brain Source Type: research

Sleep disturbances in bipolar disorder during remission
Conclusions: Psychological interventions aimed at encouraging the adoption of more stable sleep and daily routines might be helpful in helping individuals with BD cope more efficiently with some of these complaints. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - February 26, 2013 Category: Neurology Authors: Julie St-Amand, Martin D. Provencher, Lynda Bélanger, Charles M. Morin Tags: Preliminary Communications Source Type: research

Lack of sleep not the killer it's made out to be
Conclusion This small crossover study found that insufficient sleep causes changes in the levels of RNA in the blood. However, there are some important limitations: Only a week of insufficient sleep compared to a week of sufficient sleep was examined. It is not known whether the RNA changes indicate what would happen in the longer term if a person continuously had less than six hours of sleep a night, for example over a number of years. The people in this trial were all young, healthy adults who normally got around eight hours sleep a night, so it is not clear if the findings of this research would apply to the wider...
Source: NHS News Feed - February 26, 2013 Category: Consumer Health News Tags: Genetics/stem cells Lifestyle/exercise Source Type: news

Impaired health-related quality of life after chemoradiotherapy for anal cancer: Late effects in a national cohort of 128 survivors.
Conclusions. Survivors after chemoradiotherapy for anal cancer have significant long-term impairment of HRQOL. Reduced social, role and sexual function, and increased diarrhoea, incontinence for gas and stools, and buttock pain were commonly reported. Increased awareness of this may lead to better management of late effects and better care for cancer survivors. PMID: 23438358 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - February 26, 2013 Category: Cancer & Oncology Authors: Bentzen AG, Balteskard L, Wanderås EH, Frykholm G, Wilsgaard T, Dahl O, Guren MG Tags: Acta Oncol Source Type: research

Sleep assessment of children with cerebral palsy: Using validated sleep questionnaire
Conclusion: Results of our study indicate that CP children have high incidence of sleep problem in both pre-school and school age groups. (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - February 25, 2013 Category: Neurology Authors: Riad M ElsayedBothina M HasaneinHala E SayyahMostafa M El-AuotyNoha TharwatTamer M Belal Source Type: research

Major depressive disorder and factorial dimensions among individuals with recent-onset spinal cord injury.
Conclusions: The rate of single episodes of MDD determined by the IDD parallels the rate observed with the Patient Health Questionnaire–9 (PHQ-9). The factor structure of the IDD was similar to that reported by Frank et al. (1992). Information provided by the IDD about the presence and severity of MDD symptoms can inform interventions for persons with SCI. (PsycINFO Database Record (c) 2013 APA, all rights reserved) (Source: Rehabilitation Psychology)
Source: Rehabilitation Psychology - February 25, 2013 Category: Rehabilitation Authors: Williamson, Meredith L. C.; Elliott, Timothy R. Source Type: research

Citrus aurantium L. essential oil exhibits anxiolytic-like activity mediated by 5-HT1A-receptors and reduces cholesterol after repeated oral treatment
Conclusion: This work contributes to a better understanding of the biological activity of C. aurantium EO by characterizing the mechanism of action underlying its anxiolytic-like activity. (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - February 22, 2013 Category: Complementary Medicine Authors: Celso CostaThaís CuryBruna CassettariRegina TakahiraJorge FlórioMirtes Costa Source Type: research

Worry over antipsychotic drugs in care homes
Conclusion This study looks at the changing use of psychotropic medication in older people moving from the community into care homes in Northern Ireland. Researchers found a sharp increase in people being prescribed these medicines once they enter care. The study was well conducted and uses reliable national data on community prescriptions. However, as the authors point out, it has some limitations: Most importantly, the study did not have clinical information for the individuals included in the study, so it could not assess whether drug prescriptions were appropriate or not. Individual care homes were not identifie...
Source: NHS News Feed - February 21, 2013 Category: Consumer Health News Tags: Medication Older people Neurology Source Type: news

Neurim Pharmaceuticals Announces Positive Phase 2 Clinical Trial Results Of Piromelatine For The Treatment Of Insomnia
Neurim Pharmaceuticals have announced positive results from a phase II clinical study evaluating the efficacy and safety of Piromelatine (Neu-P11), a novel investigational multimodal sleep medicine developed for the treatment of patients with primary and co-morbid insomnia. The new results are from a recent double-blind, randomized, placebo controlled, parallel group, non-confirmatory, sleep-laboratory study. The study evaluated piromelatine compared to placebo in 120 adult primary insomnia patients ages 18 years and older... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 20, 2013 Category: Consumer Health News Tags: Sleep / Sleep Disorders / Insomnia Source Type: news

Healthy Sleep, Healthy Diet: Sleep Pattern Linked To Variety Of Food Intake
People who eat a large variety of foods, considered an indicator of a healthy diet, are also the ones with the healthiest sleep patterns, according to a new study from the Perelman School of Medicine at the University of Pennsylvania (Penn), in the US. The researchers write about their findings in a paper that is available to read online, ahead of the May print issue of the journal Appetite. First author Michael A... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 20, 2013 Category: Consumer Health News Tags: Sleep / Sleep Disorders / Insomnia Source Type: news

Insomnia Study May Lead To Reduction In The Risk Of Suicide In People With Depressive Symptoms
A new study confirms a link between insomnia and thoughts of suicide and suggests that this relationship is mediated by dysfunctional beliefs and attitudes about sleep as well as nightmares. The study suggests that the targeted assessment and treatment of specific sleep problems may reduce the risk of suicide in people with depressive symptoms. "Insomnia and nightmares, which are often confused and go hand-in-hand, are known risk factors for suicide but just how they contribute was unknown," said Dr. W... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 18, 2013 Category: Consumer Health News Tags: Sleep / Sleep Disorders / Insomnia Source Type: news

Neurim reports positive data from Piromelatine Phase II insomnia study
Neurim Pharmaceuticals has reported positive data from a Phase II study of Piromelatine (Neu-P11), for the treatment of primary and co-morbid insomnia. (Source: Drug Development Technology)
Source: Drug Development Technology - February 17, 2013 Category: Pharmaceuticals Source Type: news

The stalking cure: how to rehabilitate a stalker
A forensic psychiatrist has opened a clinic where stalkers confront their dangerous delusions. Elizabeth Day meets Frank Farnham, and speaks to some of the many victimsWhen forensic psychiatrist Frank Farnham first meets a stalker, he doesn't judge. Some of his clients have done awful things. They have intimidated, pursued and terrified their victims. They have sent harassing emails to ex-partners or followed work colleagues home from the office. They have developed harmful fixations on people who have no intention of returning their attentions. All of them will have run the risk of being sent to jail.But Dr Farnham sees t...
Source: Guardian Unlimited Science - February 17, 2013 Category: Science Authors: Elizabeth Day Tags: Psychology Mental health UK criminal justice Society Law Features The Observer Source Type: news

How To Get A Great Night's Sleep: Could Less Mean More?
If you regularly struggle to fall asleep, it might be better to try and restrict rather than extend the amount of time you spend in bed. According to the new Good-Night Guide from The Sleep Council, sleep restriction can help people who only manage limited sleep, to fall asleep faster and wake up fewer times. It's a new approach to helping problem sleepers, the idea being to build a strong association between your bed and sleep... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 15, 2013 Category: Consumer Health News Tags: Sleep / Sleep Disorders / Insomnia Source Type: news

Primary insomnia in older persons.
PMID: 23418800 [PubMed - in process] (Source: American Family Physician)
Source: American Family Physician - February 15, 2013 Category: Primary Care Authors: Alessi C, Vitiello MV Tags: Am Fam Physician Source Type: research

A Quantitative Approach to Distinguishing Older Adults with Insomnia from Good Sleeper Controls
Conclusion:Sleep diary parameters discriminated individuals with insomnia from good sleepers more accurately than actigraphy. These quantitative criteria are similar to those reported by other investigators using different methods and samples, including younger adults. The results suggest that the sleep diary, an inexpensive self-report sleep measure, may be used in clinical and research settings to help distinguish older adults with and without insomnia.Commentary:A commentary on this article appears in this issue on page 135.Citation:Levenson JC; Troxel WM; Begley A; Hall M; Germain A; Monk TH; Buysse DJ. A quantitative ...
Source: Journal of Clinical Sleep Medicine : JCSM - February 14, 2013 Category: Sleep Medicine Source Type: research

Setting Quantitative Thresholds for Detecting Insomnia in Older Persons
(Source: Journal of Clinical Sleep Medicine : JCSM)
Source: Journal of Clinical Sleep Medicine : JCSM - February 14, 2013 Category: Sleep Medicine Source Type: research

Nightmares and Dysfunctional Beliefs about Sleep Mediate the Effect of Insomnia Symptoms on Suicidal Ideation
Conclusions:Nightmares as well as dysfunctional beliefs and attitudes about sleep each are positively and independently related to the intensity of suicidal ideation, and the effect of insomnia symptoms appears to be mediated through these two variables.Citation:McCall WV; Batson N; Webster M; Case LD; Joshi I; Derreberry T; McDonough A; Farris SR. Nightmares and dysfunctional beliefs about sleep mediate the effect of insomnia symptoms on suicidal ideation. J Clin Sleep Med 2013;9(2):135–140. (Source: Journal of Clinical Sleep Medicine : JCSM)
Source: Journal of Clinical Sleep Medicine : JCSM - February 14, 2013 Category: Sleep Medicine Source Type: research

Insomnia and Epilepsy: A Questionnaire-Based Study
Conclusion:These results suggest that insomnia and poor sleep are common in patients with epilepsy and may adversely impact quality of life. Further studies should examine whether improvements in sleep can improve seizure control and quality of life of these patients.Citation:Vendrame M; Yang B; Jackson S; Auerbach SH. Insomnia and epilepsy: a questionnaire-based study. J Clin Sleep Med 2013;9(2):141–146. (Source: Journal of Clinical Sleep Medicine : JCSM)
Source: Journal of Clinical Sleep Medicine : JCSM - February 14, 2013 Category: Sleep Medicine Source Type: research

Healing Cognitive and Emotional Effects of Head Injuries
Safe and effective natural medicines can prevent or reverse the longterm effects of head injuries, including memory loss, lack of concentration, insomnia, anger, depression, and even suicidal ideation. read more (Source: Psychology Today Depression Center)
Source: Psychology Today Depression Center - February 14, 2013 Category: Psychiatry & Psychology Authors: Burke Lennihan, R.N., C.C.H. Tags: Depression Health Integrative Medicine Memory arnica bipolar disorder misdiagnosed boston university bright lights cambridge mass Cantu chronic traumatic encephalopathy concussion contact sports football dad former athletes h Source Type: news

Money, Marriage and Your Health
Source: HealthDay - Related MedlinePlus Pages: Anxiety, Family Issues, Insomnia, Women's Health (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - February 14, 2013 Category: Consumer Health News Source Type: news

Pensioner suffering from rare medical condition endures three years of sleepless nights because she hears How Much is that Doggie in the Window? on a loop in her head
Susan Root, 63, from Essex, suffers from a form of tinnitus where music plays constantly in her head - meaning she struggles to sleep and sometimes cannot hear others speak. (Source: the Mail online | Health)
Source: the Mail online | Health - February 14, 2013 Category: Consumer Health News Source Type: news

Long-Term Safety of IPX066 Extended-Release Carbidopa-Levodopa Capsules in Patients with Early Parkinson's Disease (P01.064)
CONCLUSIONS: Overall, IPX066 demonstrated a favorable tolerability profile throughout extended dosing in early PD. During open-label administration, the frequency of AEs reported was typical of this population.Supported by: Impax Pharmaceuticals.Disclosure: Dr. Nausieda has received personal compensation for activities with Impax, Novartis, UCB Pharma, and Teva Neuroscience. Dr. Nausieda holds stock and/or stock options in Teva Neuroscience, Phytopharm PLC, and Impax, which sponsored research in which Dr. Nausieda was involved as an investigator. Dr. Nausieda holds stock and/or stock options in Abbott, Bristol-Myers Squibb...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Nausieda, P., Rudzinska, M., Kell, S., O'Connell, M., Hsu, A., Gupta, S. Tags: P01 Movement Disorders: Parkinson ' s Disease Therapy Source Type: research

Long-Term Safety of IPX066 Extended-Release Carbidopa-Levodopa Capsules in Patients with Motor Fluctuations in Advanced Parkinson's Disease (P01.065)
CONCLUSIONS: Overall, IPX066 demonstrated a favorable tolerability profile during long-term management of advanced PD. Throughout open-label treatment, the percentage of patients reporting AEs was comparable to those in the original IPX066 trials.Supported by: Impax Pharmaceuticals.Disclosure: Dr. Ellenbogen has received personal compensation for activities with XenoPort, Inc., Teva Neuroscience, Boehringer Ingelheim Pharmaceuticals, Inc., Allergan, Inc., Novartis, GlaxoSmithKline, Inc. and Ipsen. Dr. Nausieda has received personal compensation for activities with Impax, Novartis, UCB Pharma, and Teva Neuroscience. Dr. Nau...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Ellenbogen, A., Nausieda, P., Pourcher, E., Rudzinska, M., Kell, S., O'Connell, M., Hsu, A., Gupta, S. Tags: P01 Movement Disorders: Parkinson ' s Disease Therapy Source Type: research

Phase 2 BOLD Extension Study Safety Results for Siponimod (BAF312) in Patients with Relapsing-Remitting Multiple Sclerosis (P01.176)
CONCLUSIONS: Siponimod was well tolerated during the first 12 months of extension, in line with the core trial, and no new safety signals were observed.Supported by: Novartis Pharma AG.Disclosure: Dr. Hartung has received personal compensation for activities with Biogen Idec, Teva Neuroscience, Sanofi-Aventis Pharmaceuticals, Inc., Bayer, Novartis, and Merck Serono. Dr. Selmaj has received personal compensation for activities with Biogen Idec, Genzyme, Ono Pharmaceutical, Novartis, Bayer, Hoffmann LaRoche, Merck, Serono and Synthon. Dr. Li has received personal compensation for activities with Genzyme, Novartis, and Nuron ...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Hartung, H.-P., Selmaj, K., Li, D., Hemmer, B., Freedman, M., Stuve, O., Rieckmann, P., Montalban, X., Ziemssen, T., Zhang-Auberson, L., Hunter, B., Rochotte, E., Wallstrom, E., Kappos, L. Tags: P01 Multiple Sclerosis: Treatment Safety Source Type: research

Abulia in a Concussed Athlete (P01.261)
CONCLUSIONS: While abulia is not a common symptom of sports related concussion, this case illustrates an interesting presentation of frontal lobe injury resulting in lack of emotion, apathy, and decreased motivation. It is important to recognize that in addition to the classic symptoms of sports concussions, less common symptoms exist such as impulsivity, depression, insomnia, and in this case, abulia.Disclosure: Dr. Madey has nothing to disclose. Dr. Williams has nothing to disclose. Dr. Bodle has nothing to disclose. Dr. Williams has nothing to disclose. Dr. Lehman has nothing to disclose. (Source: Neurology)
Source: Neurology - February 14, 2013 Category: Neurology Authors: Madey, J., Williams, E., Bodle, J., Williams, N., Lehman, R. Tags: P01 Sports Neurology Source Type: research

Interim Analysis of an Open-Label, Multi-Center Study of Ecopipam, a Dopamine D1 Receptor Antagonist, for Tic Reduction in Adults with Tourette Syndrome (P02.058)
CONCLUSIONS: In this open-label study, oral ecopipam appeared to reduce tic severity without causing weight gain. To confirm treatment safety and efficacy, further double blind, placebo-controlled randomized trials in children and in adults with TS are warranted.Supported by: Psyadon Pharmaceuticals, Inc.Disclosure: Dr. Gilbert has received personal compensation in an editorial capacity for Pediatrics Review and Education Program. Dr. Gilbert has received research support from Psyadon Pharmaceuticals and Otsuka Pharmaceuticals. Dr. Budman has received research support from Psyadon Pharmaceuticals and Otsuka Pharmaceuticals...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Gilbert, D., Budman, C., Singer, H., Kurlan, R., Kwan, R., Chipkin, R. Tags: P02 Restless Legs Syndrome, Tourette Syndrome, and Dystonia Source Type: research

Bruxism Associated with Restless Limbs Syndrome (RLS): A Dopamine Responsive Movement Disorder (P02.063)
CONCLUSIONS: These data support a strong association between RLS and bruxism, both movement disorders and parasomnias, and suggests that bruxism, in this population, may respond to treatment with DAs. Although retrospective, non-controlled, and unblinded, this study should enhance disease appreciation and encourage a blinded and placebo-controlled trial of DA for bruxism associated with RLS. Finally, the data suggest that bruxism may be a manifestation of RLS and is a dopamine-responsive movement disorder that should be well-known to, and treated by, neurologists in the future.Disclosure: Dr. Dickoff has received personal ...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Dickoff, D. Tags: P02 Restless Legs Syndrome, Tourette Syndrome, and Dystonia Source Type: research

High Prevalence of Insomnia and Shift Work in Cluster Headache (P03.106)
CONCLUSIONS: Chronic insomnia among Arctic cluster headache patients is common. The present study indicates that shift work may cause circadian misalignment and predispose for cluster headache. The high prevalences of insomnia and shift work found should be confirmed in other cluster populations.Disclosure: Dr. Ofte has nothing to disclose. Dr. Berg has nothing to disclose. Dr. Bekkelund has nothing to disclose. Dr. Alstadhaug has nothing to disclose. (Source: Neurology)
Source: Neurology - February 14, 2013 Category: Neurology Authors: Ofte, H., Berg, D., Bekkelund, S., Alstadhaug, K. B. Tags: P03 Headache: Epidemiology Source Type: research

Prescription of Complementary and Alternative Medicine (CAM) in an Italian Cohort of Pediatric Headache Patients (P03.115)
CONCLUSIONS: Our study shows that CAM is widely used among pediatric headache patients, and physicians are mostly unaware of prescription. Further studies are required to investigate safety and efficacy of CAM, as a possible side-medicine to conventional pharmacological approach.Disclosure: Dr. Colombo has nothing to disclose. Dr. Dalla Libera has nothing to disclose. Dr. Pavan has nothing to disclose. Dr. Comi has received personal compensation for activities with Novartis, Teva Neuroscience, Sanofi-Aventis Pharmaceuticals, Inc., Merck Serono, and Bayer Schering. (Source: Neurology)
Source: Neurology - February 14, 2013 Category: Neurology Authors: Colombo, B., Dalla Libera, D., Pavan, G., Comi, G. Tags: P03 Headache: Epidemiology Source Type: research

The Clinical and Forensic Toxicology of Z-drugs.
Abstract The Z-drugs zolpidem, zopiclone, and zaleplon were hailed as the innovative hypnotics of the new millennium, an improvement to traditional benzodiazepines in the management of insomnia. Increasing reports of adverse events including bizarre behavior and falls in the elderly have prompted calls for caution and regulation. Z-drugs have significant hypnotic effects by reducing sleep latency and improving sleep quality, though duration of sleep may not be significantly increased. Z-drugs exert their effects through increased γ-aminobutyric acid (GABA) transmission at the same GABA-type A receptor as benzodiaz...
Source: Journal of Medical Toxicology - February 13, 2013 Category: Toxicology Authors: Gunja N Tags: J Med Toxicol Source Type: research

Psychological functioning measures in patients with primary insomnia and sleep state misperception
ConclusionsThe study did not succeed in identifying any predictor of sleep misperception. We speculate that a group of patients, rather than being extremely worried by their insomnia, may have a sort of agnosia of their sleep. (Source: Acta Neurologica Scandinavica)
Source: Acta Neurologica Scandinavica - February 13, 2013 Category: Neurology Authors: S. Dittoni, M. Mazza, A. Losurdo, E. Testani, R. Giacopo, G. Marano, M. Nicola, B. Farina, P. Mariotti, S. Mazza, G. Della Marca Tags: Original Article Source Type: research

Sleep-dependent memory consolidation in patients with sleep disorders
Summary: Sleep can improve the off-line memory consolidation of new items of declarative and non-declarative information in healthy subjects, whereas acute sleep loss, as well as sleep restriction and fragmentation, impair consolidation. This suggests that, by modifying the amount and/or architecture of sleep, chronic sleep disorders may also lead to a lower gain in off-line consolidation, which in turn may be responsible for the varying levels of impaired performance at memory tasks usually observed in sleep-disordered patients.The experimental studies conducted to date have shown specific impairments of sleep-dependent c...
Source: Sleep Medicine Reviews - February 12, 2013 Category: Sleep Medicine Authors: Carlo Cipolli, Michela Mazzetti, Giuseppe Plazzi Tags: Clinical reviews Source Type: research

BDNF: an indicator of insomnia?
BDNF: an indicator of insomnia? Molecular Psychiatry advance online publication, February 12 2013. doi:10.1038/mp.2013.10 Authors: M Giese, E Unternährer, H Hüttig, J Beck, S Brand, P Calabrese, E Holsboer-Trachsler & A Eckert (Source: Molecular Psychiatry)
Source: Molecular Psychiatry - February 12, 2013 Category: Psychiatry Authors: M GieseE UnternährerH HüttigJ BeckS BrandP CalabreseE Holsboer-TrachslerA Eckert Source Type: research

Changes in Provider Treatment Preferences for Insomnia (Kyle Hoedebecke MD)
(Source: Family Medicine Digital Resources Library (FMDRL) Recently Uploaded)
Source: Family Medicine Digital Resources Library (FMDRL) Recently Uploaded - February 12, 2013 Category: Primary Care Source Type: news

Factors Associated With Fatigue After Surgery in Women With Early-Stage Invasive Breast Cancer.
Conclusion. These results suggest that worsening fatigue after surgery for breast cancer is associated with a decrease in physical functioning and an increase in psychological distress rather than with the cancer characteristics. Therefore, screening measures should be implemented at the time of diagnosis-before starting treatment-to identify psychologically vulnerable patients and to offer them professional support. PMID: 23404818 [PubMed - as supplied by publisher] (Source: The Oncologist)
Source: The Oncologist - February 12, 2013 Category: Cancer & Oncology Authors: Rotonda C, Guillemin F, Bonnetain F, Velten M, Conroy T Tags: Oncologist Source Type: research

Residual symptoms and functioning in depression: does the type of residual symptom matter? a post-hoc analysis
Conclusions: Different residual symptoms are associated to different degrees with patient functioning. To achieve normal functioning, specific residual symptoms domains might be targeted for treatment. (Source: BMC Psychiatry - Latest articles)
Source: BMC Psychiatry - Latest articles - February 11, 2013 Category: Psychiatry Authors: Irene RomeraVíctor PérezAntonio CiudadLuis CaballeroMiguel RocaPepa PolaviejaInmaculada Gilaberte Source Type: research

In Sickness and in Wealth: Psychological and Sexual Costs of Income Comparison in Marriage
This article studies this impact through sexual and mental health problems. Using wage and prescription medication data from Denmark, we implement a regression discontinuity design to show that men outearned by their wives are more likely to use erectile dysfunction medication than their male breadwinner counterparts, even when this inequality is small. Breadwinner wives suffer increased insomnia/anxiety medication usage, with similar effects for men. We find no effects for unmarried couples or for men who earned less than their fiancée prior to marriage. Our results suggest that social norms play important roles in...
Source: Personality and Social Psychology Bulletin - February 11, 2013 Category: Psychiatry & Psychology Authors: Pierce, L., Dahl, M. S., Nielsen, J. Tags: Articles Source Type: research

Twin Pregnancies: Evaluation of Major Depression, Stress, and Social Support.
Conclusion: Major depression occurs in one-third of pregnant women expecting twins and is associated with higher levels of stress and lack of social support. A multidisciplinary approach in these cases is fundamental to minimize further risks and complications. PMID: 23398666 [PubMed - as supplied by publisher] (Source: Twin Research and Human Genetics)
Source: Twin Research and Human Genetics - February 11, 2013 Category: Genetics & Stem Cells Authors: Benute GR, Nozzella DC, Prohaska C, Liao A, de Lucia MC, Zugaib M Tags: Twin Res Hum Genet Source Type: research