Measles
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Inequitable childhood immunization uptake in Nigeria: A multilevel analysis of individual and contextual determinants.
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Conclusion:
Significant community-level variation remaining after having controlled for child- and mother-level characteristics is indicative of a need for further research on community-levels factors, which would enable extensive tailoring of community-level interventions aimed at improving full immunization and other child health outcomes. (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - November 20, 2009 Category: Infectious Diseases Authors: Diddy Antai Source Type: journals
Namibia: Measles Vaccination Campaign Starts in Khomas Region Today!
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The Ministry of Health and Social Services begins a measles vaccination drive in the Khomas Region today, and is calling on the parents of all children aged six- to 59 months (just under five years old) to get their children to the nearest clinic to be vaccinated. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 18, 2009 Category: African Health Source Type: news
Global Update: Congo’s Army Accused of Striking Villages as Refugees Waited for Measles Shots
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The medical charity Doctors Without Borders has accused the Congolese Army of attacking the villages of Rwandan refugees as they waited for measles shots offered by the charity. (Source: NYT > Health)
Source: NYT > Health - November 17, 2009 Category: Consumer Health News Authors: By DONALD G. McNEIL Jr. Tags: Congo (Formerly Zaire) measles Hutu Tribe War Crimes, Genocide and Crimes Against Humanity Defense and Military Forces Medicine and Health Humanitarian Aid Source Type: news
10 Technologies That Made News In 2009 And Warrant Watching In 2010
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A first-of-its kind inhalable measles vaccine for developing countries, where the disease remains a scourge. A "nanogenerator" that could recharge iPods and other electronic devices with a shake. And for Fido and Fluffy, a long-awaited once-a-month pill for both ticks and fleas. It's list season, the time to prepare inventories of what stood out in 2009 and holds promise for the year ahead. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 17, 2009 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news
10 Technologies That Made News In 2009 And Warrant Watching In 2010
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A first-of-its kind inhalable measles vaccine for developing countries, where the disease remains a scourge. A "nanogenerator" that could recharge iPods and other electronic devices with a shake. And for Fido and Fluffy, a long-awaited once-a-month pill for both ticks and fleas. It's list season, the time to prepare inventories of what stood out in 2009 and holds promise for the year ahead. (Source: Immune System / Vaccines News From Medical News Today)
Source: Immune System / Vaccines News From Medical News Today - November 17, 2009 Category: Allergy & Immunology Tags: Infectious Diseases / Bacteria / Viruses Source Type: news
CKS topic review: Measles
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Source: CKS
Area: Evidence > Guidelines
This Topic Review from the Clinical Knowledge Service (CKS) covers the management of acute measles and post-exposure prophylaxis for measles.
This topic does not cover the prevention of measles with the combined measles, mumps, and rubella (MMR) vaccine. (Source: NeLM - Infections)
Source: NeLM - Infections - November 17, 2009 Category: Infectious Diseases Source Type: organizations
Glogal Update: Congo’s Army Accused of Striking Villages as Refugees Waited for Measles Shots
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The medical charity Doctors Without Borders has accused the Congolese Army of attacking the villages of Rwandan refugees as they waited for measles shots offered by the charity. (Source: NYT > Health)
Source: NYT > Health - November 16, 2009 Category: Consumer Health News Authors: By DONALD G. McNEIL Jr. Tags: Congo (Formerly Zaire) measles Hutu Tribe War Crimes, Genocide and Crimes Against Humanity Defense and Military Forces Medicine and Health Humanitarian Aid Source Type: news
Nigeria: Time to Fight Pneumonia
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Pneumonia is the biggest cause of child deaths around the world, especially third world countries. An infection of the lungs which causes cough and fever and can make breathing difficult, the disease kills about two million children under five years of age every year. It kills more children than malaria, measles and HIV/AIDS combined. More than 98 per cent of these deaths occur in just 68 developing countries. This is because childhood pneumonia is strongly linked to malnutrition, poverty and inadequate access to health care. And, unfortunately, Nigeria is one of these 68 high burden countries. In Nigeria, 20 per cent of a...
Source: AllAfrica News: Health and Medicine - November 16, 2009 Category: African Health Source Type: news
List makers take note: 10 technologies that made news in 2009 and warrant watching in 2010
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(American Chemical Society) A first-of-its kind inhalable measles vaccine for developing countries, where the disease remains a scourge. A "nanogenerator" that could recharge iPods and other electronic devices with a shake. And for Fido and Fluffy, a long-awaited once-a-month pill for both ticks and fleas. Those three advances are among hundreds publicized during 2009 by the American Chemical Society, the world's largest scientific society. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 16, 2009 Category: Global & Universal Source Type: news
[Newsdesk] Childhood vaccination and progress towards MDG4
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Agencies and individuals worldwide are continuing their efforts to vaccinate the world's children and their achievements are highlighted by State of the World's Vaccines and Immunization, a major report published recently by WHO, UNICEF, and The World Bank. “We have good news…”, announced Daisy Mafubelu, Assistant Director General of Family and Community Health at WHO (Geneva, Switzerland). “The number of children being vaccinated is now at an all time high—and we have the numbers to prove this.” In 2008, 106 million children received routine vaccinations for childhood killer infectious diseases including measl...
Source: The Lancet Infectious Diseases - November 16, 2009 Category: Infectious Diseases Authors: Kathryn Senior Tags: Newsdesk Source Type: journals
Efforts to Combat Global Childhood Malnutrition Woefully Underfunded
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This report documents the fact that nutrition interventions that have been proven to reduce deaths remain catastrophically underfunded.”
MSF used data from the OECD, European Commission, World Bank, Gates Foundation and UNITAID to analyze the funding flows of the main international donors. Although billions of dollars of international assistance are labelled “development food aid and food security” or “emergency food aid,” less than two percent is being spent on interventions targeted specifically at reducing childhood malnutrition. Moreover, existing funds are being wasted through inefficient...
Source: MSF News - November 11, 2009 Category: Global & Universal Source Type: organizations
Rome: Food summit to fail if governments continue spending peanuts on childhood malnutrition
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This report documents the fact that nutrition interventions that have been proven to reduce deaths remain catastrophically underfunded.”
MSF used data from the European Commission, the World Bank and the Gates Foundation to analyze the funding flows of the main international donors. The organization also used information from the Organization for Economic Cooperation and Development as well as UNITAID, the UN body addressing access to affordable medicines for HIV, malaria and tuberculosis. Although billions of dollars of international assistance are labelled “development food aid and food security” or “emergency f...
Source: MSF News - November 11, 2009 Category: Global & Universal Tags: NEWS Italy Source Type: organizations
Rome Food Summit to Fail if Governments Continue Spending Peanuts on Childhood Malnutrition
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This report documents the fact that nutrition interventions that have been proven to reduce deaths remain catastrophically underfunded.”MSF used data from the OECD, European Commission, World Bank, Gates Foundation and UNITAID to analyse the funding flows of the main international donors. Although billions of dollars of international assistance are labelled “development food aid and food security” or “emergency food aid,” less than two percent is being spent on interventions targeted specifically at reducing childhood malnutrition. Moreover, existing funds are being wasted through inefficient practices, such as t...
Source: MSF News - November 11, 2009 Category: Global & Universal Source Type: organizations
Zimbabwe: Measles Hits Apostolic Sects
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Thirty-five measles cases, mostly among members of apostolic sects aged between nine months and 21 years, have been reported across the country, the Ministry of Health and Child Welfare has said. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 11, 2009 Category: African Health Source Type: news
Kinetics of antibody persistence following administration of a combination meningococcal serogroup C and Haemophilus influenzae type b conjugate vaccine at 12 to 15 months of age in healthy UK infants primed with two doses of one of three monovalent meningococcal serogroup C vaccines.
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The kinetics of antibody persistence following the administration of a combination meningococcal serogroup C and Haemophilus influenzae type b (Hib) conjugate vaccine (Menitorix) in the second year of life in children primed with two doses of one of three monovalent meningococcal serogroup C (MCC) vaccines was investigated. Study subjects were either administered Menitorix at 12 to 15 months of age followed by the 7-valent pneumococcal conjugate (PCV7) and measles, mumps and rubella (MMR) vaccine 4 to 6 weeks later or all three vaccines concomitantly at 12 to 15 months of age. Blood samples were collected before and 1,...
Source: Clinical and Vaccine Immunology - November 11, 2009 Category: Allergy & Immunology Authors: Borrow R, Andrews N, Findlow H, Waight P, Southern J, Crowley-Luke A, Stapley L, England A, Findlow J, Miller E Tags: Clin Vaccine Immunol Source Type: journals
Flu could kill 80,000 people in Europe
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Death figures are likely to be a 'gross understimate' claim European expertsRelated items from OnMedicaDrugmakers 'on track' to produce swine flu vaccine England to get a swine flu 'tzar' Health Secretary announcesScottish Bill passed to protect public from contaminationThere is no quick test for swine flu Measles deaths fall sharply globally (Source: OnMedica Latest News)
Source: OnMedica Latest News - November 9, 2009 Category: UK Health Source Type: news
DRC: MSF vaccination used as bait in attack on civilians
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Thousands of people came under fire last month by the Congolese army at seven vaccination sites operated by international medical humanitarian organization Médecins Sans Frontières (MSF). The army is fighting against the Forces Démocratiques de Libération du Rwanda (FDLR) in North Kivu, Democratic Republic of Congo (DRC). According to UN figures, 62 civilians died in the attacks.
MSF denounces this clearly unacceptable violation against civilians through the abuse of humanitarian aid for military purposes.
MSF medical teams were vaccinating thousands of children in seven different sites in Ngomashi and Kimua zones, c...
Source: MSF News - November 6, 2009 Category: Global & Universal Tags: Democratic Republic of Congo NEWS Source Type: organizations
DR Congo: MSF Vaccination Used as Bait in Unacceptable Attack on Civilians
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Kinshasa, November 6, 2009 – Last month, seven vaccination sites operated by the international medical humanitarian organization Doctors Without Borders/Médecins Sans Frontières (MSF) came under fire during attacks by the Congolese army against the Forces Démocratiques de Libération du Rwanda (FDLR) in North Kivu, Democratic Republic of Congo (DRC). Thousands of civilians had gathered at the sites. MSF denounces this clearly unacceptable abuse of humanitarian aid for military purposes.
MSF launched a mass vaccination campaign in Masisi district to support the Congolese ministry of health i...
Source: MSF News - November 6, 2009 Category: Global & Universal Source Type: organizations
H1N1 vaccines too little, too late; most people already exposed and immune (opinion)
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(NaturalNews) The Big Pharma frenzy over H1N1 vaccines has turned into a circus of hilarious medical quackery thanks to the fact that by the time the vaccines are available, most people will have already been exposed to the virus. Hence, most people will have already built up their own H1N1 antibodies, rendering the vaccine not just useless, but downright laughable.Even with the outlandish rush to get these vaccines approved by the FDA -- a hurry that saw the complete abandonment of the principles of "scientific testing" -- Big Pharma just couldn't get these vaccines produced quickly enough to beat the virus itself. Taking...
Source: NaturalNews.com - November 6, 2009 Category: Consumer Health Advice Source Type: news
Demonstration of anti-tumor activity of oncolytic measles virus strains in a malignant pleural effusion breast cancer model
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Abstract Breast cancer is the second leading cause of malignant effusions in cancer patients. Pleural effusion indicates incurable
disease with limited palliative treatment options and poor outcome. Here, we demonstrate the therapeutic efficacy of measles
virus (MV) vaccine strain derivative against malignant pleural effusion in an MDA-MB-231 xenograft model of advanced breast
cancer. Both systemic intravenous (i.v.) and intrapleural (t.t.) administered virus caused massive infection and syncytia
formation in the pleural tumor deposits. Intrapleural administration of 1.5 × 106 plaque-forming units...
Source: Breast Cancer Research and Treatment - November 5, 2009 Category: Cancer & Oncology Tags: Breast Cancer Research and Treatment Source Type: journals
Also In Global Health News: Childhood Vaccines; USAID Administrator; Pakistan Polio Fight; UNICEF Fundraising; Measles In India
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The International Examines Contributing Factors To Uneven Distribution Of Childhood Vaccines As a follow-up to the release of the State of the World's Vaccines and Immunization by the WHO, UNICEF and World Bank last month, (Source: Pediatrics News From Medical News Today)
Source: Pediatrics News From Medical News Today - November 5, 2009 Category: Pediatrics Tags: Immune System / Vaccines Source Type: news
Also In Global Health News: Childhood Vaccines; USAID Administrator; Pakistan Polio Fight; UNICEF Fundraising; Measles In India
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The International Examines Contributing Factors To Uneven Distribution Of Childhood Vaccines As a follow-up to the release of the State of the World's Vaccines and Immunization by the WHO, UNICEF and World Bank last month, The International examines the findings that "despite ch (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 5, 2009 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news
News Outlets Examine First World Pneumonia Day
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To mark the first World Pneumonia Day, Inter Press Service examines how vaccines and other strategies can be used to combat the disease, which kills more children under age 5 each year "than measles, malaria, and AIDS combined, according to the Global Coalition against Child Pneumonia. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 4, 2009 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news
ProQuad
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The Approval Letter and Approved Final Draft Labeling for Merck's Efficacy Supplement for Measles, Mumps, Rubella, and Varicella Vaccine, Live, (ProQuad®), to include concomitant administration with hepatitis A vaccine (VAQTA®) and/or pneumococcal conjugate vaccine (Prevnar®), use of ProQuad® in children 15 months to 12 years of age if a second dose of measles, mumps, rubella, and varicella is needed, additional safety data after a first or second dose of ProQuad®, and to comply with the Physician’s Labeling Rule format, have been issued. (Source: What's New at CBER)
Source: What's New at CBER - November 3, 2009 Category: Biomedical Science Source Type: organizations
Poor progress is made in India's effort to control measles
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(Source: BMJ Online First)
Source: BMJ Online First - November 3, 2009 Category: Journals (General) Authors: Mudur, G. Tags: Infectious diseases, Epidemiologic studies, Immunology (including allergy), Infection (neurology), Neuromuscular disease, Spinal cord, Health of indigenous peoples NEWS Source Type: journals
Pig DNA is mapped
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The advance could improve vaccines against swine flu, say expertsRelated items from OnMedicaDrugmakers 'on track' to produce swine flu vaccine There is no quick test for swine flu Middle-aged women may benefit from HPV vaccine Measles programme must be stepped-upWorld not well prepared for swine flu (Source: OnMedica Latest News)
Source: OnMedica Latest News - November 3, 2009 Category: UK Health Source Type: news
What Does It Cost to Save a Life?
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The answer: less than $1. Through cost-effective vaccinations, the Measles Initiative has helped to save 3.6 million lives over the last decade. On this podcast episode, volunteer Sandy Tesch discusses her trip to The Gambia to observe a vaccination campaign. For more information on the Initiative, check out MeaslesInitiative.org.
Also: the Facebook Gift Store has added a virtual gift for 60 credits to vaccinate 5 children in the developing world from measles. Send it to your friends!
>> Listen Now
>> Episodes 1-12 of Cross the Globe
You can subscribe to this podcast in iTunes by going to your iTunes Store and ...
Source: Red Cross Chat - November 2, 2009 Category: Global & Universal Authors: Mat Morgan Tags: Podcast International Source Type: organizations
Pneumonia: Vaccination Essential To Prevent World's Leading Child Killer
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Marking the first international World Pneumonia Day on 2 November, the GAVI Alliance plans to immunise 130 million children in poor countries against pneumonia, the world's leading child killer. Pneumonia, a severe inflammation of the lungs usually caused by infection, is responsible for one in four child deaths, more than HIV/AIDs, malaria and measles combined. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 2, 2009 Category: Consumer Health News Tags: Respiratory / Asthma Source Type: news
Transverse myelitis and vaccines: a multi-analysis.
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Transverse myelitis is a rare clinical syndrome in which an immune-mediated process causes neural injury to the spinal cord. The pathogenesis of transverse myelitis is mostly of an autoimmune nature, triggered by various environmental factors, including vaccination. Our aim here was to search for and analyze reported cases of transverse myelitis following vaccination. A systematic review of PubMed, EMBASE and DynaMed for all English-language journals published between 1970 and 2009 was preformed, utilizing the key words transverse myelitis, myelitis, vaccines, post-vaccination, vaccination and autoimmunity. We have dis...
Source: Lupus - November 1, 2009 Category: Rheumatology Authors: Agmon-Levin N, Kivity S, Szyper-Kravitz M, Shoenfeld Y Tags: Lupus Source Type: journals
Low immunity to measles and rubella among female guest workers, northern Mariana Islands.
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PMID: 19891896 [PubMed - in process] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - November 1, 2009 Category: Infectious Diseases Authors: Stambos V, Chaine JP, Kelly H, Sablan M, Riddell M Tags: Emerg Infect Dis Source Type: journals
Update on Cutaneous Manifestations of Infectious Diseases
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This article reviews bacterial, mycobacterial, fungal, and viral pathogens important to dermatologists. (Source: Medical Clinics of North America)
Source: Medical Clinics of North America - November 1, 2009 Category: Primary Care Authors: Dirk M. Elston Source Type: journals
Viral entry mechanisms: the increasing diversity of paramyxovirus entry
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The paramyxovirus family contains established human pathogens such as the measles virus and human respiratory syncytial virus, as well as emerging pathogens including the Hendra and Nipah viruses and the recently identified human metapneumovirus. Two major envelope glycoproteins, the attachment protein and the fusion protein, promote the processes of viral attachment and virus-cell membrane fusion required for entry. Although common mechanisms of fusion protein proteolytic activation and the mechanism of membrane fusion promotion have been shown in recent years, considerable diversity exists in the family relating to recep...
Source: FEBS Journal - October 30, 2009 Category: Research Authors: Everett C. Smith, Andreea Popa, Andres Chang, Cyril Masante, Rebecca Ellis Dutch Source Type: journals
South Africa: Measles Campaign to Reach More Than Three Million
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The Gauteng Department of Health and Social Development is scaling up its measles vaccination campaign after more cases of the disease have been reported in the province. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 27, 2009 Category: African Health Source Type: news
Parents urged to sign measles consent forms
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The Gauteng health department urged parents on Tuesday to sign consent forms for their children to be inoculated against measles before the end of the month. (Source: IOL: Health)
Source: IOL: Health - October 27, 2009 Category: African Health Source Type: news
Measles outbreak: Joburg prison quarantined
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A ten-day quarantine has been declared at a Johannesburg prison with 51 cases of measles. (Source: IOL: Health)
Source: IOL: Health - October 26, 2009 Category: African Health Source Type: news
Philippines: Ongoing aid to the most vulnerable almost a month after violent tropical storms
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In Manila and surrounding areas, tens of thousands of people are still living in very critical conditions in crowded evacuation centres or partially flooded houses, following the devastation of the storms that hit four and three weeks ago.
These living conditions expose the population to waterborne and contagious diseases and close medical follow-up is critical.
In the slums near a canal east of Manila and in all affected areas of Laguna Bay, MSF has been running mobile primary healthcare clinics with referrals to local hospitals.
“The most frequent diseases we see are respiratory and skin infections as well as dia...
Source: MSF News - October 23, 2009 Category: Global & Universal Tags: NEWS Source Type: organizations
Zimbabwe: Measles Claim Four Children
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Four children below the age of five died of measles in an outbreak suspected to have been triggered by unvaccinated children who recently came from South Africa. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 23, 2009 Category: African Health Source Type: news
Infection of bovine dendritic cells by rinderpest or measles viruses induces different changes in host transcription.
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The morbilliviruses are a closely related genus which are very similar in their sequences and share a common receptor, but nevertheless show significant restriction in the host species in which they cause disease. One contribution to this restriction might be the nature of the hosts' responses to infection. We have used microarrays to study the changes in the transcriptome of bovine dendritic cells after infection with wild-type (pathogenic) and vaccine (apathogenic) strains of rinderpest virus (RPV), a bovine pathogen, and a wild-type isolate of measles virus (MV), a morbillivirus that causes disease only in humans an...
Source: Virology - October 23, 2009 Category: Virology Authors: Nanda SK, Baron J, Royall E, Robinson L, Falciani F, Baron MD Tags: Virology Source Type: journals
Reporting of MMR evidence in professional publications: 1988-2007
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Conclusion:
While a period of neutrality may reflect a professional response to uncertainty by holding back until consensus emerges, it may also represent a missed opportunity to promote evidence-based practice. (Source: Archives of Disease in Childhood)
Source: Archives of Disease in Childhood - October 22, 2009 Category: Pediatrics Authors: Hilton, S, Hunt, K, Langan, M, Hamilton, V, Petticrew, M Tags: Dentistry and oral medicine Original articles Source Type: journals
Some model based considerations on observing generation times for communicable diseases.
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The generation time of an infectious disease is usually defined as the time from the the moment one person becomes infected until that person infects another person. The concept is similar to "generation gap" in demography, with new infections replacing births in a population. Originally applied to diseases such as measles where at least the first generations are clearly discernible, the concept has recently been extended to other diseases, such as influenza, where time order of infections is usually much less apparent. By formulating the relevant statistical questions within a simple yet basic mathematical model for i...
Source: Mathematical Biosciences - October 22, 2009 Category: Statistics Authors: Scalia Tomba G, Svensson K, Asikainen T, Giesecke J Tags: Math Biosci Source Type: journals
Autophagy Induction by the Pathogen Receptor CD46.
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We report here that the engagement of CD46, a ubiquitous human surface receptor able to bind several different pathogens, is sufficient to induce autophagy. CD46-Cyt-1, one of the two C-terminal splice variants of CD46, is linked to the autophagosome formation complex VPS34/Beclin1 via its interaction with the scaffold protein GOPC. Measles virus and group A Streptococcus, two CD46-binding pathogens, induce autophagy through a CD46-Cyt-1/GOPC pathway. Thus, upon microorganism recognition, a cell surface pathogen receptor can directly trigger autophagy, a critical step to control infection.
PMID: 19837375 [PubMed - in p...
Source: Cell Host and Microbe - October 21, 2009 Category: Microbiology Authors: Joubert PE, Meiffren G, Grégoire IP, Pontini G, Richetta C, Flacher M, Azocar O, Vidalain PO, Vidal M, Lotteau V, Codogno P, Rabourdin-Combe C, Faure M Tags: Cell Host Microbe Source Type: journals
South Africa: Measles Vaccine is Safe, Assures Dept
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The Department of Health has reassured parents and guardians that the current measles jab being dispensed at schools as part of the measles vaccination campaign is safe. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 21, 2009 Category: African Health Source Type: news
Measles: about 1 000 cases confirmed
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There are 1 135 confirmed cases of measles in the country - and Gauteng is leading with the number of diagnosed people. (Source: IOL: Health)
Source: IOL: Health - October 21, 2009 Category: African Health Source Type: news
UN-backed vaccination scheme in Tajikistan achieves almost universal success
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Nearly every Tajik child between the ages of one and 14 received vaccinations against measles and rubella during a two-week, United Nations-backed campaign this month to fight the spread of the diseases in the mountainous Central Asian country. (Source: UN News Centre - Health, Poverty, Food Security)
Source: UN News Centre - Health, Poverty, Food Security - October 21, 2009 Category: Global & Universal Source Type: organizations
South Africa: Authorities All Out to Avert Measles Spread
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As the number of measles infections continues to climb in Gauteng, authorities in the province are going all out to avert a further spread of the pandemic. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 20, 2009 Category: African Health Source Type: news
South Africa: Over 120,000 Immunised in Measles Campaign
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The Gauteng Health Department has immunised 123 232 people since the launch of its measles immunisation campaign last Monday. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 19, 2009 Category: African Health Source Type: news
[Reflection and Reaction] Has routine immunisation in Africa become endangered?
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The broad picture of immunisation in Africa is one of excellent progress and enthusiastic energy, with amazing advances having been made since the turn of the century. There has been a large drop in mortality due to measles, and about a third of countries now use a three dose regimen of diphtheria-tetanus-pertussis triple vaccine (DTP3), which provides coverage of at least 80% in all districts. However, a review of immunisation in Africa found that all is not well. (Source: The Lancet Infectious Diseases)
Source: The Lancet Infectious Diseases - October 18, 2009 Category: Infectious Diseases Authors: Yemane Berhane, C John Clements, Jean Michel Ndiaye, Patricia Taylor Tags: Reflection and Reaction Source Type: journals
RNA-specific Adenosine Deaminase ADAR1 Suppresses Measles Virus-induced Apoptosis and Activation of Protein Kinase PKR [Rna-Mediated Regulation and Noncoding Rnas]
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ADAR1 (adenosine deaminase acting on RNA) catalyzes the conversion of adenosine to inosine, a process known as A-to-I editing. Extensive A-to-I editing has been described in viral RNAs isolated from the brains of patients persistently infected with measles virus, although the precise role of ADAR during measles virus infection remains unknown. We generated human HeLa cells stably deficient in ADAR1 ("ADAR1kd cells") through short hairpin RNA-mediated knockdown, and using these cells, we tested the effect of ADAR1 deficiency on measles virus (MVvac strain) growth and virus-induced cell death. We found that the growth of mut...
Source: Journal of Biological Chemistry - October 16, 2009 Category: Chemistry Authors: Toth, A. M., Li, Z., Cattaneo, R., Samuel, C. E. Tags: Rna-Mediated Regulation and Noncoding Rnas Source Type: journals
South Africa: Dept Confirms Four Measles Deaths, 940 Cases
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The Department of Health has confirmed that four people have died since an outbreak of measles earlier this year. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 16, 2009 Category: African Health Source Type: news
