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Middle East Respiratory Syndrome coronavirus (MERS-CoV) – Saudi Arabia
Between 18 and 21 August 2015, the National IHR Focal Point for the Kingdom of Saudi Arabia notified WHO of 29 additional cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection, including 6 deaths. Twenty-four (24) of these reported cases are associated with a MERS-CoV outbreak currently occurring in a hospital in Riyadh city. (Source: WHO Disease Outbreaks)
Source: WHO Disease Outbreaks - August 26, 2015 Category: Infectious Diseases Tags: coronavirus [subject], coronavirus infections, coronavirus [subject], coronavirus infections, coronavirus [subject], coronavirus infections, headache [subject], headache, migraine, chronic headache, hygiene [subject], disinfection, disinfect, Disease outb Source Type: news

Balance Disorders in Postural Orthostatic Tachycardia Syndrome (POTS)
Background: Postural Orthostatic Tachycardia Syndrome (POTS) is a form of dysautonomia that is estimated to impact between 1,000,000 and 3,000,000 Americans, and millions more around the world. POTS is a form of orthostatic intolerance that is associated with the presence of excessive tachycardia and many other symptoms like Headache, Abdominal discomfort, Dizziness/presyncope, Balance disorder, Nausea, Fatigue, Lightheadedness, Sweating, Sleep disorder, Tremor, Anxiety, Palpitations, Exercise intolerance upon standing. (Source: Autonomic Neuroscience: Basic and Clinical)
Source: Autonomic Neuroscience: Basic and Clinical - August 26, 2015 Category: Neuroscience Authors: Chandralekha Ashangari, Amer Suleman, Sadaf Syed Tags: P17.13 Source Type: research

Adjunctive brexpiprazole 1 and 3 mg for patients with major depressive disorder following inadequate response to antidepressants: a phase 3, randomized, double-blind study.
CONCLUSIONS: Brexpiprazole 3 mg demonstrated efficacy versus placebo in the efficacy population per final protocol. Both doses of brexpiprazole were well tolerated. TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT01360632. PMID: 26301771 [PubMed - as supplied by publisher] (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - August 26, 2015 Category: Psychiatry Tags: J Clin Psychiatry Source Type: research

Efficacy and safety of oxytocin augmentation therapy for schizophrenia: an updated systematic review and meta-analysis of randomized, placebo-controlled trials.
Authors: Oya K, Matsuda Y, Matsunaga S, Kishi T, Iwata N Abstract The aim of this study was to perform a systematic review and an updated and comprehensive meta-analysis of oxytocin augmentation therapy in patients with schizophrenia who received antipsychotic agents. Data published up to 07/11/2015 were obtained from PubMed, PsycINFO, and Cochrane Library databases. We conducted a systematic review and meta-analysis of patients' data from randomized controlled trials (RCTs) comparing oxytocin with placebo. Relative risk (RR), standardized mean difference (SMD), and 95 % confidence intervals (95 % CI) based on th...
Source: European Archives of Psychiatry and Clinical Neuroscience - August 26, 2015 Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research

Healing, and Human Touch
Early this summer, I spent several days in a hospital bed, tethered to an IV, with what proved in retrospect to be anaplasmosis (a nasty bit of tick-borne business), complicated by viral meningitis. The latter was likely due to the immunosuppression of the primary infection. It was all rather unpleasant. Among other things, I had a constant, moderate headache punctuated by crushing head pain- easily, the worst headaches I've ever experienced. I was given narcotics when the pain was at its worst, and they didn't do much for me, despite their two distinct advantages. The first is that these drugs are genuinely effective at t...
Source: Healthy Living - The Huffington Post - August 26, 2015 Category: Consumer Health Advice Source Type: news

Triptans in the Acute Treatment of MigraineTriptans in the Acute Treatment of Migraine
This meta-analysis examined the evidence for the efficacy, effectiveness, and safety of various triptans for acute treatment of migraines. How did they compare with other migraine-relief options? Headache (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 26, 2015 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

A single‐ and multiple‐dose study to investigate the pharmacokinetics of epelsiban and its metabolite, GSK2395448, in healthy female volunteers
Abstract An open‐label single‐ and repeat‐dose study was conducted to investigate the pharmacokinetics, safety, and tolerability of ascending doses of epelsiban in healthy female volunteers (n = 48). The pharmacokinetics of the epelsiban metabolite, GSK2395448, were also assessed. Epelsiban was readily absorbed and parent and metabolite readily appeared in plasma. The parent drug's median tmax was approximately 0.5 hours, and the metabolite's median tmax ranged from 0.5 to 1.0 hours post–parent dosing. Both epelsiban and GSK2395448 had rapid elimination half‐lives, ranging between 2.66 and 4.85 hours. The met...
Source: Clinical Pharmacology in Drug Development - August 26, 2015 Category: Drugs & Pharmacology Authors: Kelly M. Mahar, Brendt Stier, Michael Fries, Stewart W. McCallum Tags: Original Manuscript Source Type: research

Health effects of aspirin: Where do we stand?
An aspirin a day, keeps the doctor away. Or does it? Aside from being a potent painkiller to help with that numbing headache or aching pain in your back, doctors today routinely prescribe a daily regimen of aspirin to help prevent heart attack and st... (Source: WDSU.com - Health)
Source: WDSU.com - Health - August 25, 2015 Category: Consumer Health News Source Type: news

Diagnostic Algorithm for Patients With Suspected Giant Cell Arteritis
Conclusions: We propose a clinical algorithm that is highly predictive for a positive TAB and can be valuable in the evaluation process of suspected cases of GCA. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2015 Category: Opthalmology Tags: Original Contribution Source Type: research

Clinical use of the {beta}3 adrenoceptor agonist mirabegron in patients with overactive bladder syndrome
Mirabegron is a β3 adrenoceptor agonist licensed for the treatment of overactive bladder symptoms, such as urinary urgency or urgency incontinence. β3 adrenoceptor activation causes detrusor muscle relaxation, but mirabegron may also act by binding other targets in the bladder, and it may also reduce activity in sensory nerves. Phase III clinical trials (SCORPIO, ARIES, and CAPRICORN) evaluated mirabegron at various doses, demonstrating reduction from baseline to endpoint in mean incontinence episodes and mean number of micturitions per 24 h (coprimary endpoints), along with health-related quality of life and a r...
Source: Therapeutic Advances in Urology - August 25, 2015 Category: Urology & Nephrology Authors: Vij, M., Drake, M. J. Tags: Reviews Source Type: research

Headache, dysphasia and a left temporal lobe mass
Publication date: Available online 24 August 2015 Source:Journal of Clinical Neuroscience Author(s): Kiryu K. Yap, David Oehme, Tiew F. Han (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - August 25, 2015 Category: Neuroscience Source Type: research

Intraventricular Hemorrhage from a Glioblastoma in the Medulla Oblongata of an Adolescent: A Potential Diagnostic Pitfall
A 16-year-old boy was admitted because of sudden headache followed by coma. Computed tomography (CT) scan showed isolated intraventricular hemorrhage (IVH; Fig A). He underwent ventricular drainage and became alert postoperatively. The provisional diagnosis, in the absence of of pathognomonic laboratory and imaging results, was primary IVH. Non-enhanced magnetic resonance imaging (MRI) 2 months later revealed a small lesion in the medulla (Fig B, C). This lesion, which had not been clearly visible on the prior CT images, was diagnosed as a part of residual hematoma. (Source: Pediatric Neurology)
Source: Pediatric Neurology - August 25, 2015 Category: Neurology Authors: Hiroki Toda, Mitsuaki Shirahata, Koichi Iwasaki Tags: Visual Diagnosis Source Type: research

Coffee and depression: a short review of literature.
Abstract Coffee is among the most widespread and healthiest beverages in the world. It is known to be a highly rich source of biologically active natural metabolites which possess therapeutic effects (i.e. caffeine) and functional properties (i.e. chlorogenic acids). Therefore, coffee can be considered a drink which has different positive effects on human health such as cardioprotective, neuroprotective, hepatoprotective, nephroprotective, etc. However, heavy coffee consumption may be related to some unpleasant symptoms, mainly anxiety, headache, increased blood pressure, nausea, and restlessness. During the past t...
Source: Current Pharmaceutical Design - August 25, 2015 Category: Drugs & Pharmacology Authors: Tenore GC, Daglia M, Orlando V, D'Urso E, Saadat SH, Novellino E, Nabavi SF, Nabavi SM Tags: Curr Pharm Des Source Type: research

Meet RoboDoc: Could Robots Make Doctors Obsolete?
If you've ever felt the first twinge of a headache and immediately headed over to Google to look up your symptoms and find a potential treatment, you could be inadvertently contributing to a vision of the future. One where our regular GPs are replaced with automated diagnosis and robots. Nor are you alone for that matter. A recent survey in the UK by The UK Digital Health Report, found that 1 in 4 adults were seeking diagnosis online and that this rate was increasing by a massive 20 percent per year. Experts are now predicting that a combination of technological advancements and robotics could soon render much of a docto...
Source: Science - The Huffington Post - August 24, 2015 Category: Science Source Type: news

Efficacy and safety of oxytocin augmentation therapy for schizophrenia: an updated systematic review and meta-analysis of randomized, placebo-controlled trials
Abstract The aim of this study was to perform a systematic review and an updated and comprehensive meta-analysis of oxytocin augmentation therapy in patients with schizophrenia who received antipsychotic agents. Data published up to 07/11/2015 were obtained from PubMed, PsycINFO, and Cochrane Library databases. We conducted a systematic review and meta-analysis of patients’ data from randomized controlled trials (RCTs) comparing oxytocin with placebo. Relative risk (RR), standardized mean difference (SMD), and 95 % confidence intervals (95 % CI) based on the random-effects model were calculated. We included se...
Source: European Archives of Psychiatry and Clinical Neuroscience - August 24, 2015 Category: Neuroscience Source Type: research

What You Need To Know About The New Libido Pill For Women
By: Elizabeth Palermo Published: 08/21/2015 10:58 AM EDT on LiveScience Some health professionals are reacting with more enthusiasm than others about the first approved drug aimed at increasing women's sexual desire. Known generically as flibanserin and sold under the brand name Addyi, the medication could be prescribed as early as Oct.17, said Sprout Pharmaceuticals, the company that developed the so-called "little pink pill." Many have compared Addyi to Viagra, the medication for men with erectile dysfunction that increases blood flow to the penis. But the new pill for women aims to boost women's libidos by affecting lev...
Source: Science - The Huffington Post - August 24, 2015 Category: Science Source Type: news

Influenza follicles in the posterior pharyngeal wall
Introduction Influenza develops rapidly with a high fever accompanying chills and malaise. Respiratory symptoms such as nasal discharge, cough and sore throat, gastrointestinal symptoms such as vomiting and diarrhoea, headache, joint pain, muscle pain, etc., frequently accompany it, but they are non-specific symptoms. On the other hand, influenza follicles in the posterior pharyngeal wall are very characteristic physical findings for the seasonal influenza diagnosis.1 Sakuma’s well-known paediatric pharynx findings textbook in Japan2 notes influenza follicles in the posterior pharyngeal wall. However, the textbook is...
Source: Postgraduate Medical Journal - August 24, 2015 Category: Journals (General) Authors: Kenzaka, T. Tags: Journalology, Immunology (including allergy), Drugs: infectious diseases, Headache (including migraine), Pain (neurology), Hypertension, Clinical diagnostic tests, Ear, nose and throat/otolaryngology, Ethics Images in medicine Source Type: research

Capsaicin-sensitive C- and A-fibre nociceptors control long-term potentiation-like pain amplification in humans
In conclusion, all nociceptor subclasses contribute to high frequency stimulation-induced pain (with a relative contribution of C > A fibres, and an equal contribution of TRPV1-positive and TRPV1-negative fibres). TRPV1-positive C-fibres are the main inducers of both homotopic and heterotopic pain–long-term potentiation. TRPV1-positive A-fibres contribute substantially to the induction of heterotopic pain–long-term potentiation. TRPV1-negative C-fibres induce a component of homotopic self-facilitation but not heterotopic pain–long-term potentiation. TRPV1-negative A-fibres are the main afferents mediat...
Source: Brain - August 24, 2015 Category: Neurology Authors: Henrich, F., Magerl, W., Klein, T., Greffrath, W., Treede, R.-D. Tags: Pain and Headache Original Articles Source Type: research

Migraine and risk of stroke in older adults: Northern Manhattan Study
Conclusion: In our racially/ethnically diverse population-based cohort, migraine was associated with an increased risk of stroke among active smokers but not among nonsmokers. (Source: Neurology)
Source: Neurology - August 24, 2015 Category: Neurology Authors: Monteith, T. S., Gardener, H., Rundek, T., Elkind, M. S. V., Sacco, R. L. Tags: Migraine, All Cerebrovascular disease/Stroke, Cardiac; see Cerebrovascular Disease/Cardiac, Risk factors in epidemiology ARTICLE Source Type: research

Myopia/heavy eye syndrome: A rare cause of horizontal diplopia
A 30-year-old woman with myopia (–8 diopters) developed binocular horizontal diplopia over a year. She had chronic migraine and no other symptoms. Ocular motility showed a comitant esotropia (20 diopters), and 2-diopter right hypertropia. MRI (figures 1 and 2) showed features of heavy eye syndrome,1 which is associated with superotemporal prolapse of the posterior globe, degeneration of lateral rectus–superior rectus band, and displacement of the lateral rectus downward.2 The abduction failure may be confused with a sixth nerve palsy. Our patient was treated with prisms with partial success, which along with st...
Source: Neurology - August 24, 2015 Category: Neurology Authors: Narayana, K. M., Nusbaum, A., Galetta, S. L. Tags: MRI, Ocular motility, Diplopia (double vision) NEUROIMAGES Source Type: research

Whole Course Neuroendoscopic Resection of Cerebellopontine Angle Epidermoid Cysts
Conclusions The characteristics of epidermoid cysts make them amenable to whole course neuroendoscopic resection. Use of physiologic/pathologic interspaces and neuroendoscopic angulations decreases traction on the brain, improves complete resection rates, and decreases postoperative complications.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: Journal of Neurological Surgery Part A: Central European Neurosurgery)
Source: Journal of Neurological Surgery Part A: Central European Neurosurgery - August 24, 2015 Category: Neurosurgery Authors: Hu, ZhiqiangGuan, FengKang, TiejiangHuang, HuiDai, BinZhu, GuangtongMao, BeibeiKang, Zhuang Tags: Original Article Source Type: research

Cavity Forming Pneumonia Due to Staphylococcus aureus Following Dengue Fever.
Abstract While visiting Malaysia, a 22-year-old previously healthy Japanese man developed myalgia, headache, and fever, leading to a diagnosis of classical dengue fever. After improvement and returning to Japan after a five day hospitalization, he developed productive cough several days after defervescing from dengue. Computed tomography (CT) thorax scan showed multiple lung cavities. A sputum smear revealed leukocytes with phagocytized gram-positive cocci in clusters, and grew an isolate Staphylococcus aureus sensitive to semi-synthetic penicillin; he was treated successfully with ceftriaxone and cephalexin. This ...
Source: The American Journal of Tropical Medicine and Hygiene - August 24, 2015 Category: Tropical Medicine Authors: Miyata N, Yoshimura Y, Tachikawa N, Amano Y, Sakamoto Y, Kosuge Y Tags: Am J Trop Med Hyg Source Type: research

Caput medusae with occipital headache
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - August 23, 2015 Category: Neurology Source Type: research

Orthostatic “ice pick” headache
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - August 23, 2015 Category: Neurology Source Type: research

Acute orthostatic headache and diplopia due to a spinal subarachnoid haemorrhage
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - August 23, 2015 Category: Neurology Source Type: research

Utility of CT head in the acute setting: value of contrast and non-contrast studies
Conclusion Head CT in ED non-traumatic neurological presentations with CECTH is not generally indicated and represents a calculable cost savings in the management of these patients. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - August 23, 2015 Category: Journals (General) Source Type: research

Drugs and the kidney.
This article on drug nephrotoxicity is detailed, as it is important to be fully aware of renal side-effects of drugs with regard to prevention andearly diagnosis in order to manage the condition correctly. Many therapeutic agents are nephrotoxic, particularly when the serum half-life isprolonged and blood levels are raised because of decreased renal excretion. Distal nephrotoxicity is markedly enhanced when the glomerularfiltration rate (GFR) is reduced and is a particular threat in elderly patients with so-called 'normal' creatinine levels. In patients of 45 - 55 years of age theGFR is reduced by about 1 mL/min/year, so t...
Source: South African Medical Journal - August 22, 2015 Category: African Health Tags: S Afr Med J Source Type: research

A cross sectional study between the prevalence of chronic pain and academic pressure in adolescents in China (Shanghai)
Conclusion: Chronic pain is a common condition in Chinese adolescents and is closely related to self-reported academic pressure. (Source: BMC Musculoskeletal Disorders)
Source: BMC Musculoskeletal Disorders - August 22, 2015 Category: Orthopaedics Authors: Yongxing ZhangGuoying DengZhiqing ZhangQian ZhouXiang GaoLiqing DiQianzi CheXiaoyu DuYun CaiXuedong HanQinghua Zhao Source Type: research

Clinical Analysis of 156 Cases of Multiple Organ Failure Caused by Fish Bile
Conclusions Compared with the MOF caused by trauma and sepsis, the fish bile poisoning MOF has a much lower morality rate. However, patients with higher age, more underlying diseases, and more organ failure tended to have a worse prognosis. (Source: Toxicology Reports)
Source: Toxicology Reports - August 22, 2015 Category: Toxicology Source Type: research

Effects of sumatriptan nasal spray (Imigran) on isolated rat’s tracheal smooth muscle
We examined the effectiveness of Imigran on isolated rat tracheal smooth muscle by testing: (1) effect on tracheal smooth muscle resting tension; (2) effect on contraction caused by 10−6 M methacholine as a parasympathetic mimetic; (3) effect of the drugs on electrically induced tracheal smooth muscle contractions. The results indicated that the addition of methacholine to the incubation medium caused the trachea to contract in a dose-dependent manner. The addition of Imigran at doses of 10−5 M or above elicited a significant relaxation response to 10−6 M methacholine-induced contraction. Imigran could inhibit ele...
Source: European Archives of Oto-Rhino-Laryngology - August 21, 2015 Category: ENT & OMF Source Type: research

'Mutant' Lice More Hype Than Headache
(MedPage Today) -- Treatment failure doesn't equal clinical resistance (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - August 21, 2015 Category: Dermatology Source Type: news

Underdiagnosis of depression in an economically deprived population in Macao, China
This study was designed to evaluate the prevalence of depressive symptoms and their impact on health‐related quality of life (HRQoL) in a low‐income population in Macao. MethodsThis cross‐sectional study targeted the adult beneficiaries of local food bank program. The program was established to provide food assistance to the residents who had low income but were ineligible for government financial assistance. All data were collected through interview and questionnaires. The Patient Health Questionnaire (PHQ‐9) was used for assessing depressive symptoms. Information about depression diagnosis was obtained by the sel...
Source: Asia-Pacific Psychiatry - August 21, 2015 Category: Psychiatry Authors: Cheng‐Kin Lao, Yok‐Man Chan, Henry Hoi‐Yee Tong, Alexandre Chan Tags: Original Article Source Type: research

Microwave frequency electromagnetic fields (EMFs) produce widespread neuropsychiatric effects including depression
Publication date: Available online 21 August 2015 Source:Journal of Chemical Neuroanatomy Author(s): Martin L. Pall Non-thermal microwave/lower frequency electromagnetic fields (EMFs) act via voltage-gated calcium channel (VGCC) activation. Calcium channel blockers block EMF effects and several types of additional evidence confirm this mechanism. Low intensity microwave EMFs have been proposed to produce neuropsychiatric effects, sometimes called microwave syndrome, and the focus of this review is whether these are indeed well documented and consistent with the known mechanism(s) of action of such EMFs. VGCCs occur in v...
Source: Journal of Chemical Neuroanatomy - August 21, 2015 Category: Neuroscience Source Type: research

Child with acute methotrexate related neurotoxicity: Can diffusion weighted MRI help??
Conclusion Methotrexate can result in reversible neurotoxicity in the form of white matter injury. DWI may be used in early detection of such changes; therefore, it provides a rapid, noninvasive readily available tool by which neurotoxicity can be early detected and treated. It has the potential to alert the oncologist to this event and provide a technique by which neurotoxicity can be monitored. (Source: The Egyptian Journal of Radiology and Nuclear Medicine)
Source: The Egyptian Journal of Radiology and Nuclear Medicine - August 21, 2015 Category: Nuclear Medicine Source Type: research

Source localization of intermittent rhythmic delta activity in a patient with acute confusional migraine: cross-spectral analysis using standardized low-resolution brain electromagnetic tomography (sLORETA)
Abstract Acute confusional migraine (ACM) shows typical electroencephalography (EEG) patterns of diffuse delta slowing and frontal intermittent rhythmic delta activity (FIRDA). The pathophysiology of ACM is still unclear but these patterns suggest neuronal dysfunction in specific brain areas. We performed source localization analysis of IRDA (in the frequency band of 1–3.5 Hz) to better understand the ACM mechanism. Typical IRDA EEG patterns were recorded in a patient with ACM during the acute stage. A second EEG was obtained after recovery from ACM. To identify source localization of IRDA, statistical non-para...
Source: Neurological Sciences - August 21, 2015 Category: Neurology Source Type: research

Warfarin prophylaxis in migraine without aura but not in primary exercise headache
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - August 21, 2015 Category: Neurology Source Type: research

SUNCT (Short-lasting unilateral neuralgiform headache attack with conjunctival injection and tearing) associated with pituitary lesion
Publication date: September 2015 Source:Neurología (English Edition), Volume 30, Issue 7 Author(s): L. Pulido Fontes, S. Mayor Gómez (Source: Neurologia)
Source: Neurologia - August 21, 2015 Category: Neurology Source Type: research

Chronic Migraineurs Form Carboxyhemefibrinogen and Iron-Bound Fibrinogen.
Abstract Chronic migraine (CM) is a disabling painful condition that is associated with dementia and thrombotic disease. It has been proposed that carbon monoxide (CO) and iron may play a role in CM, and CO and iron are products of heme oxygenase system which is widespread within the brain. Further, CO and iron enhance plasmatic coagulation in part via a fibrinogen-dependent mechanism. Thus, our goal was to determine whether patients with CM had experienced carboxyhemefibrinogen formation, iron bound fibrinogen formation and plasmatic hypercoagulability. Nonsmokers with CM were recruited after informed, written con...
Source: CNS and Neurological Disorders Drug Targets - August 21, 2015 Category: Drugs & Pharmacology Authors: Nielsen VG Tags: CNS Neurol Disord Drug Targets Source Type: research

Severe Headache During Pregnancy May Signal Trouble
Study found it could be tied to raised risk of complications in women with high blood pressureSource: HealthDay Related MedlinePlus Pages: Headache, Health Problems in Pregnancy, High Blood Pressure in Pregnancy (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - August 20, 2015 Category: Consumer Health News Source Type: news

The Truth About This So-Called 'Smart Drug'
By: Laura Geggel Published: 08/19/2015 07:55 PM EDT on LiveScience The "smart drug" modafinil actually does work for some people, improving their performance on long and complex tasks, also enhancing decision-making and planning skills, a new review of studies finds. Modafinil, also known by its brand name Provigil, is approved by the Food and Drug Administration to treat people with sleep disorders such as narcolepsy. But the majority of the drug's users — such as students who take it to study for exams — use it off-label, believing it may help them focus. This is despite the lack of strong evidence to date sh...
Source: Science - The Huffington Post - August 20, 2015 Category: Science Source Type: news

Pregnant? That Headache Might Not All Be In Your Head
Being pregnant often means constantly being vigilant for “something wrong” while trying not to overreact. So if a woman gets a severe headache – one of several possible symptoms of preeclampsia – how does she know if it’s worth calling the doctor? (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - August 20, 2015 Category: Pharmaceuticals Authors: Tara Haelle Source Type: news

Neurobiology and sleep disorders in cluster headache
Abstract Cluster headache is characterized by unilateral attacks of severe pain accompanied by cranial autonomic features. Apart from these there are also sleep-related complaints and strong chronobiological features. The interaction between sleep and headache is complex at any level and evidence suggests that it may be of critical importance in our understanding of primary headache disorders. In cluster headache several interactions between sleep and the severe pain attacks have already been proposed. Supported by endocrinological and radiological findings as well as the chronobiological features, predominant th...
Source: The Journal of Headache and Pain - August 20, 2015 Category: Neurology Source Type: research

Endoscopic Endonasal Transsphenoidal Approach for Apoplectic Pituitary Tumor: Surgical Outcomes and Complications in 45 Patients
Conclusion EETA offers a safe and effective surgical option for apoplectic pituitary tumors and is associated with low morbidity and mortality.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: Journal of Neurological Surgery Part B: Skull Base)
Source: Journal of Neurological Surgery Part B: Skull Base - August 20, 2015 Category: Neurosurgery Authors: Zhan, RucaiLi, XueenLi, Xingang Tags: Original Article Source Type: research

Recovery From Anesthesia and Postoperative Nausea and Vomiting
To the Editor Anesthesia- and surgery-related independent predictors of postoperative nausea and vomiting (PONV) have been well highlighted by Jones and LaFerriere. Nevertheless, some major patient-related independent predictors seem to have been overlooked in their study. Factors contributing to the PONV include, but are not limited to, female sex, not smoking, history of PONV, motion sickness, or migraine, younger age, and duration of anesthesia. (Source: JAMA Facial Plastic Surgery)
Source: JAMA Facial Plastic Surgery - August 20, 2015 Category: Cosmetic Surgery Source Type: research

Nothing fishy about this bone
Clinical introduction A 64-year-old woman presented to the Emergency Department with the sensation of something ‘stuck in her throat’. She states she was eating fish and could now feel something to the right side of the throat. There was no evidence of airway compromise, shortness of breath, cough, retrosternal chest pain and swallowing was not affected. A soft tissue neck X-ray is organised for her (figure 1). Question Q1. Which of the following fish bones are visible on X-ray?Salmon Herring Cod Pike Q2. The X-ray showsNo abnormality An incidental finding A fishbone For the answer see page 749 From the questio...
Source: Emergency Medicine Journal - August 20, 2015 Category: Emergency Medicine Authors: Farooque, M. I., Devlin, E. Tags: Headache (including migraine), Pain (neurology), EMJ Image Challenge, Radiology, Clinical diagnostic tests, Radiology (diagnostics), Ear, nose and throat/otolaryngology, Ethics Source Type: research

The shorter, the better: A review of the evidence for a shorter contraceptive hormone-free interval.
Conclusions Shortening the HFI reduces the occurrence of bleeding-related inflammatory processes and subsequent physical and mental symptoms. The shortest interval with evidence of reproductive and sexual health benefits is provided by a 26/2 regimen. PMID: 26291185 [PubMed - as supplied by publisher] (Source: The European Journal of Contraception and Reproductive Health Care)
Source: The European Journal of Contraception and Reproductive Health Care - August 20, 2015 Category: Reproduction Medicine Authors: Graziottin A Tags: Eur J Contracept Reprod Health Care Source Type: research

Functional Brain Imaging in Migraine
Migraine is a “brain storm” characterized by abnormal visceral, sensory, autonomic and cognitive functions that often occur before, during and/or after an attack. We are unaware of a systematic method to measure the location and pain characteristic present during a migraine episode. Gray matter loss reflected by cortical thinning is a normal aging process and this association between migraine and aging is most readily highlighted by the altered course of disease in older, as compared with younger sufferers. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - August 19, 2015 Category: ENT & OMF Authors: S.J. SCRIVANI, G. BARMETTLER, J. BRAWN, N. MALEKI, E. MOULTON, R. BURSTEIN, L. BECERRA, D. BORSOOK Source Type: research

Migraine in menopausal women: a systematic review
Ripa P, Ornello R, Degan D, Tiseo C, Stewart J, Pistoia F, Carolei A, Sacco S (Source: International Journal of Womens Health)
Source: International Journal of Womens Health - August 19, 2015 Category: OBGYN Source Type: research

Facilitated Subcutaneous Immunoglobulin (fSCIg) Therapy – Practical Considerations
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - August 19, 2015 Category: Allergy & Immunology Authors: Mark Ponsford, Emily Carne, Clare Kingdon, Charis Joyce, Colin Price, Christopher Williams, Tariq El‐Shanawany, Paul Williams, Stephen Jolles Tags: Original Article Source Type: research

A Randomized Clinical Trial of Nefopam versus Ketorolac Combined With Oxycodone in Patient-Controlled Analgesia after Gynecologic Surgery.
CONCLUSION: Nefopam showed a similar efficacy and lower incidence of nausea within 6 h after the operation to that of ketorolac in PCA. Nefopam may be a useful analgesic drug for the opioid-based PCA after gynecologic surgery. Further evaluation of accurate equivalent dose of nefopam as well as pharmacokinetics of bolus administration is required. PMID: 26283884 [PubMed - in process] (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - August 19, 2015 Category: Biomedical Science Tags: Int J Med Sci Source Type: research