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The course of headache in idiopathic intracranial hypertension: a 12‐month prospective follow‐up study
ConclusionsAlthough headache in 43% of patients responded well to ICP management, sustained long‐term headache was seen in the remaining patients, despite resolution of papilledema. Headache in IIH may thus be attributed to more complex mechanisms than ICP elevation alone. High ICP and young age were associated with better headache outcome. Early treatment according to standard guidelines seems sufficient to ensure excellent visual outcome in the vast majority of patients. (Source: European Journal of Neurology)
Source: European Journal of Neurology - July 29, 2014 Category: Neurology Authors: H. M. Yri, C. Rönnbäck, M. Wegener, S. Hamann, R. H. Jensen Tags: Original Article Source Type: research

Abnormal fingernail beds following carbon monoxide poisoning: a case report and review of the literature
Conclusions: Worldwide, carbon monoxide poisoning is a potentially lethal condition that is preventable with educational programs and installation of carbon monoxide detectors in the home setting. Exposure to carbon monoxide frequently goes unrecognized until it is too late and causes silent death. To the best of the authors' knowledge, this is the first report in the literature of fingernail bed manifestations in a survivor of carbon monoxide poisoning. (Source: BioMed Central)
Source: BioMed Central - July 29, 2014 Category: Journals (General) Authors: Mehrangiz HatamiFrederick NaftolinMasood A Khatamee Source Type: research

CAM in the Real WorldCAM in the Real World
Like it or not, your patients are probably using alternative therapies to treat their headache, and will continue to do so. So you'd better be up to speed on what's in their arsenal. Headache (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 28, 2014 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

Rare Primary HeadachesRare Primary Headaches
A brief primer on the presentation, pathophysiology, and treatment options of rare headache disorders, including nummular and hypnic headaches and headache associated with cold, exercise, or sex. Current Opinion in Neurology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 28, 2014 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

Non-endoscopic migraine surgery provides significant symptom relief
(Massachusetts General Hospital) A revised version of a surgical procedure to treat severe chronic migraine headaches led to significant symptom relief more than 90 percent of the time in 35 patients treated at Massachusetts General Hospital. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 28, 2014 Category: Global & Universal Source Type: news

Should You Take Zoloft for Bipolar Disorder?
Some of the most common Zoloft side effects are sweating, stomach problems and headache. Blurred vision and others are among the less common, some of which can be serious. If you are taking Zoloft for bipolar disorder, depression or any other condition, knowing all the potential side effects is important. (Source: Bipolar Disorder)
Source: Bipolar Disorder - July 28, 2014 Category: Psychiatry Authors: at Tags: health Source Type: news

Peripheral Calcitonin Gene‐Related Peptide Receptor Activation and Mechanical Sensitization of the Joint in Rat Models of Osteoarthritis Pain
ConclusionOur findings provide new and compelling evidence implicating a role of CGRP in peripheral sensitization in experimental OA. Our novel finding of CGRP‐mediated control of joint nociceptor mechanosensitivity suggests that the CGRP receptor system may be an important target for the modulation of pain during OA. CGRP receptor antagonists recently developed for migraine pain should be investigated for their efficacy against pain in OA. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - July 28, 2014 Category: Rheumatology Authors: Craig M. Bullock, Peter Wookey, Andrew Bennett, Ali Mobasheri, Ian Dickerson, Sara Kelly Tags: Osteoarthritis Source Type: research

Mystery Case: Giant mature teratoma of the lateral ventricle in a child
A 3-year-old girl was admitted with a 1-month history of headache. Neurologic examination was normal. Cranial CT revealed a mass with huge calcification in the right lateral ventricle (figure 1A). MRI demonstrated a lesion with low and high signal intensity and heterogeneous enhancement (figure 1, B–D). A right frontal craniotomy was performed. The right ventricle was found to be filled with sebaceous glands, hair, fat globules, a full set of teeth, tongue, and gastrointestinal glands (figure 2, A–D). Histologic examination confirmed a mature teratoma. Postoperative MRI demonstrated total tumor resection (figur...
Source: Neurology - July 28, 2014 Category: Neurology Authors: Li, J., Lan, Z., Xu, J. Tags: CT, MRI, Primary brain tumor, Surgical therapy-tumor, All Pediatric RESIDENT AND FELLOW SECTION Source Type: research

Gamma Knife for Obsessive Compulsive Disorder: Can It be Detrimental?
Abstract Functional neurological disorders (FND) have been a challenge to treat both for neurologists and neurosurgeons. Various ablative as well as non-ablative techniques have been used to treat these disorders. Gamma knife radiosurgery (GKRS) is also being practised to treat refractory obsessive- compulsive disorder (OCD). The subsequent complications of GKRS reported have been variable, with headache being the most common. We discuss here a rare complication of 'late onset radiation necrosis in bilateral caudate nuclei' in a patient after receiving GKRS three years back. This case highlights the need to be more...
Source: Turkish Neurosurgery - July 27, 2014 Category: Neurosurgery Authors: Tripat Hi M, Mukherjee K, Chhabra R, Radotra I, Singh AP, Radotra B Tags: Turk Neurosurg Source Type: research

Headache and spontaneous glabellar ecchymosis: more than a self injury behaviour? - Yulug B, Hanoglu L, Schabitz WR.
[Abstract unavailable] Language: en... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - July 26, 2014 Category: Global & Universal Tags: Suicide and Self-Harm Source Type: news

The experience of dysmenorrhoea among Ghanaian senior high and university students: pain characteristics and effects
Conclusions: It was concluded that severe dysmenorrhoea has a debilitating effect on female students and is associated with misconceptions that could result in drastic action with fatal consequences. Thus, there is the need to enhance education on dysmenorrhoea, and an aggressive step should be taken to effectively manage dysmenorrhoea. (Source: Reproductive Health)
Source: Reproductive Health - July 26, 2014 Category: OBGYN Authors: Lydia AziatoFlorence DedeyJoe Clegg-Lamptey Source Type: research

Humanized PA14 (a monoclonal CCR5 antibody) for treatment of people with HIV infection.
CONCLUSIONS: Limited evidence from three small trials suggests that PRO 140 might demonstrate potent, short-term, dose-dependent, highly significant antiviral activity. However, as the evidence is insufficient, recommendations cannot yet be made. Larger, longer-term, double-blind RCTs are required to provide conclusive evidence. PMID: 25063928 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - July 26, 2014 Category: Journals (General) Authors: Li L, Tian JH, Yang K, Zhang P, Jia WQ Tags: Cochrane Database Syst Rev Source Type: research

Health Tip: Easing Headache Pain
Title: Health Tip: Easing Headache PainCategory: Health NewsCreated: 7/25/2014 7:35:00 AMLast Editorial Review: 7/25/2014 12:00:00 AM (Source: MedicineNet Migraine General)
Source: MedicineNet Migraine General - July 25, 2014 Category: Neurology Source Type: news

Severe and isolated headache associated with hypertension as unique clinical presentation of posterior reversible encephalopathy syndrome
Conclusions: Severe and isolated headache associated with arterial hypertension can be the unique clinical presentation of posterior reversible encephalopathy syndrome. This syndrome must be considered even in absence of all typical symtom to prevent the progression of a potentially life threatening condition. (Source: BMC Pediatrics - Latest articles)
Source: BMC Pediatrics - Latest articles - July 25, 2014 Category: Pediatrics Authors: Gregorio MilaniAlberto EdefontiGiacomo TardiniElisa ArturiClaudia CinnanteEmanuela LaiciniErnesto LevaAlberto CappellariCarlo AgostoniEmilio Fossali Source Type: research

Negative emotions in migraineurs dreams: the increased prevalence of oneiric fear and anguish, unrelated to mood disorders.
Discussion. The brain of migraineurs seems to dream with some peculiar features, all with a negative connotation, as fear and anguish. It may be due to the recorded negative sensations induced by recurrent migraine pain, but it may just reflect a peculiar attitude of the mesolimbic structures of migraineurs brain, activated in both dreaming and migraine attacks. PMID: 25049452 [PubMed - in process] (Source: Behavioural Neurology)
Source: Behavioural Neurology - July 24, 2014 Category: Neurology Authors: De Angeli F, Lovati C, Giani L, Mariotti D'Alessandro C, Raimondi E, Scaglione V, Castoldi D, Capiluppi E, Mariani C Tags: Behav Neurol Source Type: research

Migraine Headaches, Vision Effects
Source: - July 24, 2014 Category: Journals (General) Source Type: news

The efficacy and tolerability of cariprazine in acute mania associated with bipolar I disorder: a phase II trial
ConclusionCariprazine demonstrated superior efficacy versus placebo and was generally well tolerated in patients experiencing acute manic or mixed episodes associated with bipolar I disorder. (Source: Bipolar Disorders)
Source: Bipolar Disorders - July 24, 2014 Category: Psychiatry Authors: Suresh Durgam, Anju Starace, Dayong Li, Raffaele Migliore, Adam Ruth, György Németh, István Laszlovszky Tags: Original Article Source Type: research

Everything You Need to Know About Topamax/Topir...
Topamax - generic topiramate - is an anticonvulsant approved for use in treating epilepsy and migraine headaches. It is also frequently prescribed off-label for bipolar disorder. Information on uses, major warnings, and the effectiveness of Topamax for weight loss. (Source: Bipolar Disorder)
Source: Bipolar Disorder - July 24, 2014 Category: Psychiatry Authors: at Tags: health Source Type: news

Quality of uncomplicated malaria case management in Ghana among insured and uninsured patients
Conclusion: Adherence to the standard protocol of malaria treatment is low. This is especially the case for parasitological confirmation of all suspected malaria patients before treatment with an antimalarial as currently recommended for the effective management of malaria in the country. The results show that about 16 percent of total sample were parasitologically tested. Effective management of the disease demands proper diagnosis and treatment and therefore facilities need to be adequately supplied with RDTs or be equipped with well functioning laboratories to provide adequate testing. (Source: International Journal for Equity in Health)
Source: International Journal for Equity in Health - July 24, 2014 Category: Global & Universal Authors: Ama FennyKristian HansenUlrika EnemarkFelix Asante Source Type: research

Summer first aid tips for parents
Meaghan O’Keeffe, RN, BSN, is a mother, writer and nurse. She worked at Boston Children’s Hospital for nearly a decade, in both the Cardiac Intensive Care Unit and the Pre-op Clinic.  She is a regular contributor to Thriving. Summer provides ample opportunity for enjoying nature, playing outside and gazing at skies full of stars. But some of the side effects of all that outside time—scrapes, stings and other minor injuries—can take some of the fun out of summer. Here’s a quick refresher on some basic first aid every parent should know this time of year. Insect stings and bites When it comes to insects, stay...
Source: Thrive, Children's Hospital Boston - July 23, 2014 Category: Pediatrics Authors: Guest Blogger Tags: All posts child safety Meaghan O'Keefe Parenting summer safety Source Type: news

MIGRAINE RELIEF (Not Applicable) Tablet, Orally Disintegrating [The Magni Company]
Updated Date: Jul 23, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - July 23, 2014 Category: Drugs & Pharmacology Source Type: news

Subarachnoid hemorrhage secondary to a ruptured middle cerebral aneurysm in a patient with osteogenesis imperfecta: a case report
Conclusion: The patient followed a good clinical course after surgery. It remains controversial whether IAs are caused by OI or IAs are coincidentally complicated with OI. (Source: BMC Neurology)
Source: BMC Neurology - July 23, 2014 Category: Neurology Authors: Toshio HirohataSatoru MiyawakiAkiko MizutaniTakayuki IwakamiSo YamadaHajime NishidoYasutaka SuzukiShinya MiyamotoKatsumi HoyaMineko MurakamiAkira Matsuno Source Type: research

Causes and Treatments of Migraine Headaches
Causes and Treatments of Migraine and Related Headaches (Source:
Source: - July 22, 2014 Category: Journals (General) Source Type: news

Cluster Headache FAQs
Source: - July 22, 2014 Category: Journals (General) Source Type: news

[Clinical Picture] Acute unilateral cerebellitis, Epstein-Barr virus, and HIV
A 31-year-old man presented to the emergency department with a 2-day history of severe headache, nausea, and vomiting. He reported intermittent tremors in his left hand and ataxic gait for 2 weeks. Neurological examinations showed dysarthria and left-sided dysmetria on finger-to-nose and heel-knee-shin tests. Brain MRI showed a poorly defined heterogeneous hyperintensive lesion of the left cerebellar hemisphere () and obstructive hydrocephalus caused by a cerebellar mass-effect (). Serology investigations for bacteria, fungi, and viruses indicated unremarkable results; tests for HIV and Epstein-Barr virus (EBV) were positi...
Source: The Lancet Infectious Diseases - July 22, 2014 Category: Infectious Diseases Authors: Wen-Cheng Liu, Sheng-Kang Chiu, Chih-Weim Hsiang, Te-Yu Lin Tags: Clinical Picture Source Type: research

Propagation of cortical spreading depression into the hippocampus: The role of the entorhinal cortex
Abstract Propagation of cortical spreading depression (CSD) to the subcortical structures could be the underlying mechanism of some neurological deficits in migraine with aura. The entorhinal cortex (EC) as a grey matter bridge between the neocortex and subcortical regions plays an important role in this propagation. In vitro combined neocortex‐hippocampus brain slices were used to study the propagation pattern of CSD between the neocortex and the hippocampus. The effects of different compounds as well as tetanic electrical stimulations in the EC on propagation of CSD to the hippocampus were investigated. Repetitive indu...
Source: Synapse - July 22, 2014 Category: Neurology Authors: Tanja Martens‐Mantai, Erwin‐Josef Speckmann, Ali Gorji Tags: Research Article Source Type: research

Cerebrospinal fluid and serum cytokine profiling to detect immune control of infectious and inflammatory neurological and psychiatric diseases.
Abstract The present study aimed at profiling inflammatory cytokines for neurological and psychiatric diseases. A total of 86 patients with meningitis, multiple sclerosis, tension-type headache, idiopathic facial nerve palsy (IFNP), affective and schizophrenic disorders were tested for both, serum and cerebrospinal fluid (CSF) using a multiplexed cytokine ELISA for IFN-γ, TNF-α, IL-1β, IL-2, IL-4, IL-5, IL-8/CXCL8, IL-10, IL12p70, IL-13 and IL-17. Cases with viral and bacterial meningitis had unequivocally higher cytokine concentrations in the CSF when compared with serum. Bacterial meningitis was unique by extr...
Source: Cytokine - July 21, 2014 Category: Molecular Biology Authors: Maxeiner HG, Marion Schneider E, Kurfiss ST, Brettschneider J, Tumani H, Bechter K Tags: Cytokine Source Type: research

How General Practitioners Treat Migraine in ChildrenHow General Practitioners Treat Migraine in Children
Are general practitioners following guidelines when it comes to treating migraine in children? Headache (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 21, 2014 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

What Causes Abdominal Distention?
Discussion Constipation generally is defined as infrequent or painful defecation. It often is due to passing large hard stool infrequently which causes painful defecation and then withholding behaviors. As stool withholding continues, the rectum dilates and gradually accommodates with the normal defecation urge disappearing. Chronic rectal distension results in both loss of rectal sensitivity, and loss of urge to defecate, which can lead to encopresis. Abdominal distention because of stool retention occurs frequently. Treatment includes colonic evacuation, establishing regular bowel habits, eating a balanced diet with diet...
Source: - July 21, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Bi-allelic and tri-allelic 5-HTTLPR polymorphisms and triptan non-response in cluster headache
Conclusions: Data from our study do not indicate a role of bi-allelic and tri-allelic genotypes of the 5-HTTLPR polymorphism in triptan non-response in CH. (Source: BioMed Central)
Source: BioMed Central - July 21, 2014 Category: Journals (General) Authors: Markus SchürksAntje FrahnowHans-Christoph DienerTobias KurthDieter RosskopfHans-Jörgen Grabe Source Type: research

Droxidopa for neurogenic orthostatic hypotension: A randomized, placebo-controlled, phase 3 trial
Conclusions: In patients with symptomatic nOH, droxidopa improved symptoms and symptom impact on daily activities, with an associated increase in standing systolic BP, and was generally well tolerated. Classification of evidence: This study provides Class I evidence that in patients with symptomatic nOH who respond to open-label droxidopa, droxidopa improves subjective and objective manifestation of nOH at 7 days. (Source: Neurology)
Source: Neurology - July 21, 2014 Category: Neurology Authors: Kaufmann, H., Freeman, R., Biaggioni, I., Low, P., Pedder, S., Hewitt, L. A., Mauney, J., Feirtag, M., Mathias, C. J., On behalf of the NOH301 Investigators Tags: Autonomic diseases, Low pressure syndrome, Multiple system atrophy, Clinical trials Randomized controlled (CONSORT agreement) ARTICLE Source Type: research

The Paediatric Migraine Disability Assessment Score is a useful tool for evaluating prophylactic migraine treatment
ConclusionsThe PedMIDAS scoring system is useful in evaluating the efficacy of prophylactic therapy in paediatric migraine. Topiramate and propronalol lowered the PedMIDAS scores better than flurinazine.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - July 21, 2014 Category: Pediatrics Authors: Yasemin Topcu, Semra Hiz Kurul, Erhan Bayram, Kaan Sozmen, Uluc Yis Tags: Regular Article Source Type: research

Migraine equivalents as part of migraine syndrome in childhood
(Source: Pediatric Neurology)
Source: Pediatric Neurology - July 21, 2014 Category: Neurology Authors: Samuela Tarantino, Alessandro Capuano, Roberto Torriero, Monica Citti, Catello Vollono, Simonetta Gentile, Federico Vigevano, Massimiliano Valeriani Source Type: research

Tactile sensory and pain thresholds in the face and tongue of subjects asymptomatic for oro‐facial pain and headache
Summary The aim of this study was to examine the tactile sensory and pain thresholds in the face, tongue, hand and finger of subjects asymptomatic for pain. Sixteen healthy volunteers (eight men and eight women, mean age 35·7 years, range 27–41) participated. Using Semmes–Weinstein monofilaments, the tactile detection threshold (TDT) and the filament‐prick pain detection threshold (FPT) were measured at five sites: on the cheek skin (CS), tongue tip (TT), palm side of the thenar skin (TS), dorsum of the hand (DH) and the finger tip (FT). The difference between the tactile sensory and pain threshold (FPT–TDT) was ...
Source: Journal of Oral Rehabilitation - July 19, 2014 Category: Dentistry Authors: I. Okayasu, O. Komiyama, T. Ayuse, A. De Laat Tags: Original Article Source Type: research

Multilocular bronchogenic cyst of the bilateral adrenal: report of a rare case and review of literature.
CONCLUSIONS: This report confirms the bronchogenic cyst that can be involved bilateral joint in the adrenal gland. And we demonstrated retroperitoneoscopic surgical management is effective in the treatment of the disease. PMID: 25031770 [PubMed - in process] (Source: International Journal of Clinical and Experimental Pathology)
Source: International Journal of Clinical and Experimental Pathology - July 19, 2014 Category: Pathology Authors: Cao DH, Zheng S, Lv X, Yin R, Liu LR, Yang L, Huang Y, Wei Q Tags: Int J Clin Exp Pathol Source Type: research

Features of intraventricular tanycytic ependymoma: report of a case and review of literature.
We report here another case of tanycytic ependymoma arising from the third ventricle completed with immunohistochemical, ultrastructural, and molecular pathology study. The patient was a 44 year-old male who presented with headache, nausea and visual disturbances of a few months duration. Neuroradiological findings showed a well-defined mass arising from the posterolateral wall of third ventricle. Histologically the tumor was composed of monotonous spindle cells arranged in fascicles without definitive perivascular rosettes. The tumor cells were diffusely positive for glial fibrillary acidic protein and epithelial membrane...
Source: International Journal of Clinical and Experimental Pathology - July 19, 2014 Category: Pathology Authors: Agarwal S, Stevenson ME, Sughrue ME, Wartchow EP, Mierau GW, Fung KM Tags: Int J Clin Exp Pathol Source Type: research

[Stroke in children. Experience in an emergency service].
CONCLUSIONS. CVD is a rare entity, although it presents a high morbidity and mortality rate. Haemorrhagic CVD is seen to predominate slightly and it is observed how haemorrhagic CVD presents more often with signs of intracranial hypertension, while the ischaemic form tends to have more neurological focus. PMID: 25030069 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - July 19, 2014 Category: Neurology Authors: Huici-Sanchez M, Escuredo-Argullos L, Trenchs-Sainz de la Maza V, Luaces-Cubells C Tags: Rev Neurol Source Type: research

Deficient local biological motion perception in migraineurs: results from a duration discrimination paradigm.
Abstract Migraine ranks as the third most common disease in the world and has caused significant losses of daily life abilities. Previously, people gave more attention to the pain of migraines and usually ignored the impairments of cognitive function in migraineurs. In the present study, a duration discrimination paradigm was used to assess the global and local biological motion perception in migraineurs and healthy controls. In the experiment, biological motion sequences and inanimate motion sequences (the inverted biological motion sequences) were sequentially presented on a screen. Observers were instructed to m...
Source: Brain Research - July 19, 2014 Category: Neurology Authors: Wang Q, Ye X, Hu P, Wang Y, Zhang J, Yu F, Tian Y, Wang K Tags: Brain Res Source Type: research

First report of mild Brazilian spotted fever associated to arthritis
We describe the first Brazilian case of mild Rickettsiosis, complicated by knee monoarthritis, in young adult bitten by a tick on his left leg in Camburi zone, located in São Sebastião municipality, southern coastal region of the State of São Paulo, in the Atlantic rainforest region, Brazil. The patient developed inoculation eschar at the tick bite site associated with enlarged lymph nodes in the left groin, fever, polyarthralgia, headache and macular rash. Twenty days after tick bite episode, he displayed monoarthritis in his right knee. The diagnosis of mild Rickettsiosis was established by sequential immunological an...
Source: Revista Brasileira de Reumatologia - July 18, 2014 Category: Rheumatology Source Type: research

Mosquitoes In Bridgewater Test Positive For EEE
BOSTON (CBS) – Mosquitoes in Bridgewater have tested positive for Eastern Equine Encephalitis (EEE) virus, Mass. Department of Public Health announced on Friday. The samples, collected on July 15, are the first to come back positive for EEE in the state this year. In response, officials have raised the risk level in Bridgewater to moderate. The surrounding towns of West Bridgewater, Easton, Raynham and Middleborough are already at moderate based on last year’s EEE activity. Guide: Ways To Protect Yourself From West Nile & EEE EEE is transmitted by infected mosquitoes and can be deadly. Last year, a Norfolk Cou...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - July 18, 2014 Category: Consumer Health News Authors: steve saleeba Tags: Health Local News Syndicated Local Bridgewater EASTERN EQUINE ENCEPHALITIS EEE Mosquito Triple E Source Type: news

A case of pituitary apoplexy in pregnancy.
Abstract UNLABELLED: Pituitary apoplexy is a rare event in pregnancy. A 41-year-old woman with a known pituitary microadenoma presented with visual disturbance and headache during the second trimester of pregnancy. Magnetic resonance imaging (MRI) demonstrated pituitary apoplexy with chiasmal compression. After treatment with corticosteroid therapy, she underwent transsphenoidal excision of the pituitary adenoma. Visual abnormalities were completely restored and pituitary function preserved. There was no evidence of impact on the foetus. The literature on the subject is reviewed with emphasis on the management of t...
Source: Diabetes Metab - July 18, 2014 Category: Endocrinology Authors: Hayes AR, O'Sullivan AJ, Davies MA Tags: Endocrinol Diabetes Metab Case Rep Source Type: research

Association Study of MTHFD1 Coding Polymorphisms R134K and R653Q With Migraine Susceptibility
ConclusionsWe find no evidence for association of the MTHFD1 R134K and R653Q polymorphisms with migraine in our Australian case‐control population. However, as folate metabolism appears to be important in migraine, particularly with respect to the aura component, future studies using high throughput methods to expand the number of SNPs in folate‐related genes genotyped and investigation of interactions between SNPs may be justified. (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - July 18, 2014 Category: Neurology Authors: Heidi G. Sutherland, Heloise Hermile, Rebecca Sanche, Saras Menon, Rod A. Lea, Larisa M. Haupt, Lyn R. Griffiths Tags: Research Submission Source Type: research

Behavioral Migraine Management Modifies Behavioral and Cognitive Coping in People With Migraine
ConclusionsThis study demonstrated that BMM modified important cognitive and behavioral factors postulated to be mechanisms of cognitive behavioral treatments for migraine. (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - July 18, 2014 Category: Neurology Authors: Elizabeth K. Seng, Kenneth A. Holroyd Tags: Research Submission Source Type: research

Giant Cell Arteritis
Giant cell arteritis (GCA) is a medium and large‐vessel vasculitis, which is an important cause of secondary headache in older adults. While GCA has a classic presentation occurring after the age of 50, atypical presentations (eg, fever of unknown origin, cough, low or normal erythrocyte sedimentation rate) may lead to a delay in diagnosis. The topography of vascular involvement has implications for disease‐related complications, which can result in neurologic disease at multiple levels of the nervous system. The most feared complication, vision loss, fortunately becomes uncommon after initiation of corticosteroids. Co...
Source: Headache: The Journal of Head and Face Pain - July 18, 2014 Category: Neurology Authors: Jonathan H. Smith, Jerry W. Swanson Tags: Review Article Source Type: research

Abstracts and Citations
(Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - July 18, 2014 Category: Neurology Authors: Frederick R. Taylor, Stephen H. Landy, Robert G. Kaniecki Tags: Abstracts and Citations Source Type: research

Meditation for Migraines: A Pilot Randomized Controlled Trial
ConclusionsMBSR is safe and feasible for adults with migraines. Although the small sample size of this pilot trial did not provide power to detect statistically significant changes in migraine frequency or severity, secondary outcomes demonstrated this intervention had a beneficial effect on headache duration, disability, self‐efficacy, and mindfulness. Future studies with larger sample sizes are warranted to further evaluate this intervention for adults with migraines. This study was prospectively registered ( identifier NCT01545466). (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - July 18, 2014 Category: Neurology Authors: Rebecca Erwin Wells, Rebecca Burch, Randall H. Paulsen, Peter M. Wayne, Timothy T. Houle, Elizabeth Loder Tags: Research Submission Source Type: research

Characteristics of CADASIL in Chinese mainland patients
Conclusions: Most characteristics of Chinese mainland CADASIL patients are similar to those of CADASIL patients living in other regions. However, the prevalence of primary intracerebral hemorrhage and vertigo is much higher in Chinese mainland CADASIL patients. Significant leukoaraiosis in anterior temporal poles on T2-weighted image are uncommon. Exons 3 and 4 are the mutation hotspots. (Source: Neurology India)
Source: Neurology India - July 18, 2014 Category: Neurology Authors: Qing-Che TanJia-Tang ZhangRong-Tai CuiQuan-Gang XuXu-Sheng HuangSheng-Yuan Yu Source Type: research

Migraine is a marker for risk of both ischaemic and haemorrhagic stroke
This study summarises the available evidence. Methods Sacco... (Source: Evidence-Based Medicine)
Source: Evidence-Based Medicine - July 18, 2014 Category: Internal Medicine Authors: Kurth, T. Tags: EBM Aetiology, Epidemiologic studies, Headache (including migraine), Pain (neurology), Stroke Source Type: research

Adenosine modulates light responses of rat retinal ganglion cell photoreceptors through cyclic AMP-mediated pathway.
This article is protected by copyright. All rights reserved. PMID: 25038240 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - July 18, 2014 Category: Physiology Authors: Sodhi P, Hartwick AT Tags: J Physiol Source Type: research

Perianeurysmal edema as a predictive sign of aneurysmal rupture.
Abstract Subarachnoid hemorrhage following intracranial aneurysmal rupture is a major cause of morbidity and mortality. Several factors may affect the probability of rupture, such as tobacco and alcohol use; size, shape, and location of the aneurysm; presence of intraluminal thrombus; and even the sex of the patient. However, few data correlate such findings with the timing of aneurysmal rupture. The authors report 2 cases of middle-age women with headache and MRI findings of incidental aneurysms. Magnetic resonance imaging showed evidence of surrounding parenchymal edema, and in one case there was a clear increase...
Source: Journal of Neurosurgery - July 18, 2014 Category: Neurosurgery Authors: Pahl FH, de Oliveira MF, Ferreira NP, de Macedo LL, Brock RS, de Souza VC Tags: J Neurosurg Source Type: research