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Mumps Outbreak --- New York, New Jersey, Quebec, 2009email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - November 20, 2009 Category: American Health Source Type: organizations

Viruses within the Flaviviridae Decrease CD4 Expression and Inhibit HIV Replication in Human CD4+ Cells.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Viral infections alter host cell homeostasis and this may lead to immune evasion and/or interfere with the replication of other microbes in coinfected hosts. Two flaviviruses are associated with a reduction in HIV replication or improved survival in HIV-infected people (dengue virus (DV) and GB virus type C (GBV-C)). GBV-C infection and expression of the GBV-C nonstructural protein 5A (NS5A) and the DV NS5 protein in CD4(+) T cells inhibit HIV replication in vitro. To determine whether the inhibitory effect on HIV replication is conserved among other flaviviruses and to characterize mechanism(s) of HIV inhibition, the ...
Source: Journal of Immunology - November 18, 2009 Category: Allergy & Immunology Authors: Xiang J, McLinden JH, Rydze RA, Chang Q, Kaufman TM, Klinzman D, Stapleton JT Tags: J Immunol Source Type: journals

CKS topic review: Measlesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: CKS Area: Evidence > Guidelines This Topic Review from the Clinical Knowledge Service (CKS) covers the management of acute measles and post-exposure prophylaxis for measles.   This topic does not cover the prevention of measles with the combined measles, mumps, and rubella (MMR) vaccine. (Source: NeLM - Infections)
Source: NeLM - Infections - November 17, 2009 Category: Infectious Diseases Source Type: organizations

Teaching NeuroImages: Acute hemorrhagic leukoencephalitis after mumpsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Neurology)
Source: Neurology - November 16, 2009 Category: Neurology Authors: Kumar R., S., Kuruvilla, A. Tags: MRI, DWI, All Infections, Post-infectious, Acute disseminated encephalomyelitis RESIDENT AND FELLOW SECTION Source Type: journals

Fifteen reported cases of mumps virus in last two monthsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Quebec is experiencing a mild outbreak of the mumps, a viral infection characterized by fever and inflammation of the salivary glands. (Source: CTV Health)
Source: CTV Health - November 14, 2009 Category: Consumer Health News Source Type: news

U.S. reports largest mumps outbreak in 3 yearsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
U.S. health officials say the largest U.S. outbreak of mumps in three years is occurring in New York and New Jersey. (Source: USATODAY.com Health)
Source: USATODAY.com Health - November 13, 2009 Category: Consumer Health News Source Type: news

DISPATH: Mumps Outbreak --- New York, New Jersey, Quebec, 2009email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - November 13, 2009 Category: American Health Source Type: organizations

US Reports Largest Mumps Outbreak In 3 Yearsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
U.S. health officials say the largest U.S. outbreak of mumps in three years is occurring in New York and New Jersey. (Source: WDSU.com - Health)
Source: WDSU.com - Health - November 13, 2009 Category: Consumer Health News Authors: WDSU.com Source Type: news

[Case Report] Time to revisit mumps vaccination in Japan?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In June, 2008, a 30-year-old Japanese man presented to our emergency department with a sore throat and fever. The previous day he had been to a local clinic and prescribed antibiotics and non-steroidal anti-inflammatory drugs. However, treatment was ineffective and his fever increased (up to 38·1°C). On admission, he was transferred to our otolaryngology department with possible diagnosis of acute parotitis. He had a fever (38·0°C), was hoarse, and had difficulty speaking. His neck was very swollen with redness of the skin. There was no rash. We made a preliminary diagnosis of cervical abscess, rather than parotitis. L...
Source: LANCET - November 13, 2009 Category: Journals (General) Authors: Toru Sasaki, Koichi Tsunoda Tags: Case Report Source Type: journals

Kinetics of antibody persistence following administration of a combination meningococcal serogroup C and Haemophilus influenzae type b conjugate vaccine at 12 to 15 months of age in healthy UK infants primed with two doses of one of three monovalent meningococcal serogroup C vaccines.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The kinetics of antibody persistence following the administration of a combination meningococcal serogroup C and Haemophilus influenzae type b (Hib) conjugate vaccine (Menitorix) in the second year of life in children primed with two doses of one of three monovalent meningococcal serogroup C (MCC) vaccines was investigated. Study subjects were either administered Menitorix at 12 to 15 months of age followed by the 7-valent pneumococcal conjugate (PCV7) and measles, mumps and rubella (MMR) vaccine 4 to 6 weeks later or all three vaccines concomitantly at 12 to 15 months of age. Blood samples were collected before and 1,...
Source: Clinical and Vaccine Immunology - November 11, 2009 Category: Allergy & Immunology Authors: Borrow R, Andrews N, Findlow H, Waight P, Southern J, Crowley-Luke A, Stapley L, England A, Findlow J, Miller E Tags: Clin Vaccine Immunol Source Type: journals

ProQuademail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The Approval Letter and Approved Final Draft Labeling for Merck's Efficacy Supplement for Measles, Mumps, Rubella, and Varicella Vaccine, Live, (ProQuad®), to include concomitant administration with hepatitis A vaccine (VAQTA®) and/or pneumococcal conjugate vaccine (Prevnar®), use of ProQuad® in children 15 months to 12 years of age if a second dose of measles, mumps, rubella, and varicella is needed, additional safety data after a first or second dose of ProQuad®, and to comply with the Physician’s Labeling Rule format, have been issued. (Source: What's New at CBER)
Source: What's New at CBER - November 3, 2009 Category: Biomedical Science Source Type: organizations

The role of iodine in hypersensitivity reactions to radio contrast mediaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Hypersensitivity reactions to iodinated radio contrast media (RCM) are either immediate-type (IT) or delayed reactions (DT). In IT, the pathomechanism is unclear. In DT, delayed positive patch (PT) and intradermal tests (IDT) and RCM-specific T cells suggest a T cell-mediated mechanism. In both, the role of iodine has not been clarified; however, patients are often labelled as 'iodine allergic'. Occasionally, positive skin tests to iodine-containing drugs are observed. We investigated the presence of hypersensitivity to iodine in patients with a history of hypersensitivity reactions to RCM. Nineteen patients with a history...
Source: Clinical and Experimental Allergy - November 3, 2009 Category: Allergy & Immunology Authors: K. Scherer, T. Harr, S. Bach, A. J. Bircher Source Type: journals

Viral meningitis and encephalitisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Meningitis and encephalitis due to virus infections occur at all stages of life from the neonate to the elderly and may represent disease due to the primary site of replication, e.g. rabies, or be part of a wider infection syndrome, e.g. HIV. A large proportion of cases go unconfirmed by laboratory diagnosis despite use of sensitive techniques (such as the polymerase chain reaction). They may be both sporadic and epidemic in nature, but with changing environmental and societal conditions, agents may emerge anew, e.g. Nipah and Hendra viruses, or reappear after a period of good control through vaccination, e.g. mu...
Source: Medicine - November 1, 2009 Category: Internal Medicine Authors: Philip Rice Tags: Nervous system infections Source Type: journals

Transverse myelitis and vaccines: a multi-analysis.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Transverse myelitis is a rare clinical syndrome in which an immune-mediated process causes neural injury to the spinal cord. The pathogenesis of transverse myelitis is mostly of an autoimmune nature, triggered by various environmental factors, including vaccination. Our aim here was to search for and analyze reported cases of transverse myelitis following vaccination. A systematic review of PubMed, EMBASE and DynaMed for all English-language journals published between 1970 and 2009 was preformed, utilizing the key words transverse myelitis, myelitis, vaccines, post-vaccination, vaccination and autoimmunity. We have dis...
Source: Lupus - November 1, 2009 Category: Rheumatology Authors: Agmon-Levin N, Kivity S, Szyper-Kravitz M, Shoenfeld Y Tags: Lupus Source Type: journals

Reporting of MMR evidence in professional publications: 1988-2007email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: While a period of neutrality may reflect a professional response to uncertainty by holding back until consensus emerges, it may also represent a missed opportunity to promote evidence-based practice. (Source: Archives of Disease in Childhood)
Source: Archives of Disease in Childhood - October 22, 2009 Category: Pediatrics Authors: Hilton, S, Hunt, K, Langan, M, Hamilton, V, Petticrew, M Tags: Dentistry and oral medicine Original articles Source Type: journals

Genotyping of mumps virus circulating in Turkey in the 2006–2007 winter seasonemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  In the winter of 2006–2007, several parotitis cases were reported in different provinces of Turkey. Serological and virological studies were undertaken to investigate these cases with the aim of determining the genotype of the mumps virus (MuV) circulating in Turkey. Samples from 23 cases—Ankara (n:5), Kırklareli (n:4), Mugla (n:10), Isparta (n:3), Trabzon (n:1)—with a diagnosis of clinical parotitis were investigated. Serum samples were tested against mumps IgM and IgG, nested PCR amplification of a 639-bp fragment encompassing the entire SH gene was performed using buccal swabs, and PCR prod...
Source: Archives of Virology - October 15, 2009 Category: Virology Tags: Archives of Virology Source Type: journals

Measles outbreak in Styria, Austria, March-May 2009.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In the last week of March 2009, five measles cases among students of an anthroposophic school were reported to the public health authorities in the Austrian province of Styria where only five cases had been reported in the whole of 2008. A descriptive epidemiological investigation of the measles outbreak was performed. Between 2 March and 10 May 2009, 37 cases of measles were identified in Styria: 33 confirmed outbreak cases and four probable outbreak cases. The measles outbreak spread from the general population (12 cases) to an anthroposophic community (25 cases). Cases outside of the anthroposophic community were mo...
Source: Euro Surveill - October 15, 2009 Category: Infectious Diseases Authors: Kasper S, Holzmann H, Aberle S, Wassermann-Neuhold M, Gschiel H, Feenstra O, Allerberger F, Schmid D Tags: Euro Surveill Source Type: journals

Difficulty with mumps diagnosis: What is the contribution of mumps mimickers?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Although there was co-circulation of other viral pathogens during the mumps outbreak, no difference was observed in the prevalence between patients who presented with or without parotitis. The low positivity rate for specimens submitted for mumps diagnostics was likely the result of increased Public Health messaging and physician inexperience in recognizing mumps infection, suggesting the clinical acumen for mumps diagnosis based solely on clinical presentation is low. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - October 15, 2009 Category: Virology Authors: Todd F. Hatchette, James B. Mahony, Sylvia Chong, Jason J. LeBlanc Tags: Short communications Source Type: journals

Interindividual variations in the efficacy and toxicity of vaccines.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A number of currently available vaccines have shown significant differences in the magnitude of immune responses and toxicity in individuals undergoing vaccination. A number of factors may be involved in the variations in immune responses, which include age, gender, race, amount and quality of the antigen, the dose administered and to some extent the route of administration, and genetics of immune system. Hence, it becomes imperative that researchers have tools such as genomics and proteomics at their disposal to predict which set of population is more likely to be non-responsive or develop toxicity to vaccines. In thi...
Source: Toxicology - October 14, 2009 Category: Toxicology Authors: Thomas C, Moridani M Tags: Toxicology Source Type: journals

Physical interventions and injection techniques for reducing injection pain during routine childhood immunizations: systematic review of randomized controlled trials and quasi-randomized controlled trials.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: Pain during immunization can be decreased by: (1) injecting the least painful formulation of a vaccine; (2) having the child sit up (or holding an infant); (3) stroking the skin or applying pressure close to the injection site before and during injection; (4) injecting the least painful vaccine first when 2 vaccines are being administered sequentially during a single office visit; and (5) performing a rapid intramuscular injection without aspiration. PMID: 19781436 [PubMed - in process] (Source: Clinical Therapeutics)
Source: Clinical Therapeutics - October 14, 2009 Category: Drugs & Pharmacology Authors: Taddio A, Ilersich AL, Ipp M, Kikuta A, Shah V, Tags: Clin Ther Source Type: journals

Ongoing rubella outbreak in Bosnia and Herzegovina, March-July 2009--preliminary report.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Between 24 March and 31 July 2009, 342 clinically diagnosed cases of rubella were notified in five municipalities in Republika Srpska, Bosnia and Herzegovina. Fourteen cases were laboratory-confirmed by positive IgG against rubella virus. Four virus isolates were obtained and identified as genotype 2B strains, with one isolate differing by a single mutation in the region of the E1 gene. This ongoing outbreak revealed gaps in the immunisation programme during the war in BiH (1992-1995) and highlights the need to revise legislation to permit immunisation of children above 14 years of age with measles, mumps, rubella (MMR...
Source: Euro Surveill - October 11, 2009 Category: Infectious Diseases Authors: Novo A, Huebschen JM, Muller CP, Tesanovic M, Bojanic J Tags: Euro Surveill Source Type: journals

Mumps resurgences in the United States: A historical perspective on unexpected elements.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In 2006 the United States experienced the largest nationwide mumps epidemic in 20 years, primarily affecting college dormitory residents. Unexpected elements of the outbreak included very abrupt time course (75% of cases occurred within 90 days), geographic focality (85% of cases occurred in eight rural Midwestern states), rapid upward and downward shift in peak age-specific attack rate (5-9-year olds to 18-24-year olds, then back), and two-dose vaccine failure (63% of case-patients had received two doses). To construct a historical context in which to understand the recent outbreak, we reviewed US mumps surveillance d...
Source: Vaccine - October 11, 2009 Category: Allergy & Immunology Authors: Barskey AE, Glasser JW, Lebaron CW Tags: Vaccine Source Type: journals

No Scientific Link Between Childhood Vaccines And Autism, Review Showsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A new article explores vaccination history, vaccine safety monitoring systems in the US, and the two most publicized theoretical vaccine-related exposures associated with autism -- the vaccine preservative thimerosal and the measles, mumps and rubella vaccine. A review of published research shows that there is not convincing scientific evidence supporting a relationship between vaccines and autism. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 10, 2009 Category: Science Source Type: news

Childhood Vaccines And Autism: No Scientific Link Foundemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A new article recently published in the Journal for Specialists in Pediatric Nursing explored vaccination history, vaccine safety monitoring systems in the U.S., and the two most publicized theoretical vaccine-related exposures associated with autism - the vaccine preservative thimerosal and the measles, mumps, and rubella (MMR) vaccine. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 10, 2009 Category: Consumer Health News Tags: Autism Source Type: news

No scientific link between childhood vaccines and autismemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Wiley-Blackwell) A new article recently published in the Journal for Specialists in Pediatric Nursing explored vaccination history, vaccine safety monitoring systems in the US, and the two most publicized theoretical vaccine-related exposures associated with autism -- the vaccine preservative thimerosal and the measles, mumps and rubella vaccine. A review of published research shows that there is not convincing scientific evidence supporting a relationship between vaccines and autism. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 8, 2009 Category: Global & Universal Source Type: news

Measles outbreak in Styria, Austria, March-May 2009email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In the last week of March 2009, five measles cases among students of an anthroposophic school were reported to the public health authorities in the Austrian province of Styria where only five cases had been reported in the whole of 2008. A descriptive epidemiological investigation of the measles outbreak was performed. Between 2 March and 10 May 2009, 37 cases of measles were identified in Styria: 33 confirmed outbreak cases and four probable outbreak cases. The measles outbreak spread from the general population (12 cases) to an anthroposophic community (25 cases). Cases outside of the anthroposophic community were mostly...
Source: Eurosurveillance latest news - October 8, 2009 Category: Infectious Diseases Source Type: journals

GSK expands presence in China through strategic cooperationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
GlaxoSmithKline (GSK) and Jiangsu Walvax Biotech Company (Walvax) have announced a cooperation agreement to form a long-term Joint Venture (JV) to develop and manufacture paediatric vaccines for use in China. The JV will produce vaccines for measles, mumps, and rubella (MMR) (Priorix™) and potentially other paediatric vaccines. GSK will also transfer the technology to enable the JV to manufacture the vaccines locally over time. (Source: World Pharma News)
Source: World Pharma News - October 6, 2009 Category: Pharmaceuticals Source Type: news

A prolonged mumps outbreak among highly vaccinated Aboriginal people in the Kimberley region of Western Australia.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSION: A prolonged outbreak of mumps occurred in a well defined, highly vaccinated, predominantly young Aboriginal population in the remote Kimberley region of WA. This outbreak raises questions about the effectiveness and scheduling of the current vaccine (which is genotype A-derived), especially for Aboriginal people. Surveillance of circulating mumps virus genotypes and neutralisation studies will help in evaluating the protection provided by the current vaccine against genotypically different strains. PMID: 19807634 [PubMed - in process] (Source: Med J Aust)
Source: Med J Aust - October 4, 2009 Category: Journals (General) Authors: Bangor-Jones RD, Dowse GK, Giele CM, van Buynder PG, Hodge MM, Whitty MM Tags: Med J Aust Source Type: journals

FT: Enabling Open Coreemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Fred Trotter writes: "For VA VistA we have a conundrum, the originator of the code, the US government, has left the code basically licenseless. I believe this means that the choice if preferred license should be up to the most substantial third-party developers. I believe that the most substantial way to make VistA better is to make contributions that make further development easier. MUMPS is a great language but it makes VA VistA inaccessible to most programmers. Given that I believe the most significant third-party contributions to VA VistA are (in no particular order): Medsheres OVID – because it lets you code f...
Source: GNU/Linux And Open Source Medical Software News - October 4, 2009 Category: Information Technology Source Type: news

Ongoing rubella outbreak in Bosnia and Herzegovina, March-July 2009 - preliminary reportemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Between 24 March and 31 July 2009, 342 clinically diagnosed cases of rubella were notified in five municipalities in Republika Srpska, Bosnia and Herzegovina. Fourteen cases were laboratory-confirmed by positive IgG against rubella virus. Four virus isolates were obtained and identified as genotype 2B strains, with one isolate differing by a single mutation in the region of the E1 gene. This ongoing outbreak revealed gaps in the immunisation programme during the war in BiH (1992-1995) and highlights the need to revise legislation to permit immunisation of children above 14 years of age with measles, mumps, rubella (MMR) va...
Source: Eurosurveillance latest news - October 1, 2009 Category: Infectious Diseases Source Type: journals

NICE costing template on reducing the differences in uptake of immunisations in children and young peopleemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: NICE Area: News The costing statement accompany the NICE public health guidance on reducing the differences in uptake of immunisations in children and young people notes that the national resources required to implement the recommendations made cannot be quantified.    Many public sector organisations already have strategies, policies and procedures in place to support immunisation programmes and should be able to implement the recommendations using existing resources.  The government already funds immunisation programmes and the Department of Health has made additional funding available for mea...
Source: NeLM - Immunology and vaccination - September 22, 2009 Category: Allergy & Immunology Source Type: organizations

Understanding and Determining the Etiology of Autism.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Worldwide, the rate of autism has been steadily rising. There are several environmental factors in concert with genetic susceptibilities that are contributing to this rise. Impaired methylation and mutations of mecp2 have been associated with autistic spectrum disorders, and related Rett syndrome. Genetic polymorphisms of cytochrome P450 enzymes have also been linked to autism, specifically CYP27B1 that is essential for proper vitamin D metabolism. Vitamin D is important for neuronal growth and neurodevelopment, and defects in metabolism or deficiency have been implicated in autistic individuals. Other factors that hav...
Source: Cellular and Molecular Neurobiology - September 22, 2009 Category: Cytology Authors: Currenti SA Tags: Cell Mol Neurobiol Source Type: journals

National, state, and local area vaccination coverage among adolescents aged 13-17 years--United States, 2008.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This report summarizes results from the 2008 NIS-Teen and, for the first time, includes estimates for each of the 50 states and selected local areas. Nationally, vaccination coverage for the three most recently recommended adolescent vaccinations and one childhood vaccination increased from 2007 to 2008: MCV4 (from 32.4% to 41.8%), Tdap (from 30.4% to 40.8%), >/=1 dose of HPV4 (from 25.1% to 37.2%), and >/=2 doses of VAR among those without disease history (from 18.8% to 34.1%). However, substantial variability in vaccination coverage was observed in 2008 among state and local areas and by race/ethnicity and poverty ...
Source: MMWR Morb Mortal Wkl... - September 17, 2009 Category: Epidemiology Tags: MMWR Morb Mortal Wkly Rep Source Type: journals

Development of a Focus Reduction Neutralization Test (FRNT) for Detection of Mumps Virus Neutralizing Antibodies.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, FRNT has similar sensitivity to the PRNT and offers the advantages of speed (2 vs. 7 days), reduced sample volume (40mul vs. 150mul), and the possibility of automation using 96-well plates. FRNT appears to be a good substitute for PRNT for characterising the immune response to mumps and for vaccine efficacy studies. PMID: 19761798 [PubMed - as supplied by publisher] (Source: Journal of Virological Methods)
Source: Journal of Virological Methods - September 13, 2009 Category: Virology Authors: Vaidya SR, Brown DW, Jin L, Samuel D, Andrews N, Brown KE Tags: J Virol Methods Source Type: journals

Facial palsy caused by mumps parotitisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Incecik Faruk, Herguner M Ozlem, Altunbasak SakirNeurology India 2009 57(4):511-512 (Source: Neurology India)
Source: Neurology India - September 10, 2009 Category: Neurology Authors: Incecik Faruk, Herguner M Ozlem, Altunbasak Sakir Source Type: journals

Medical and Nursing Students with Suboptimal Protective Immunity against Vaccine‐Preventable Diseases • email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. We have determined that there is a certain proportion of healthcare students who are susceptible to certain vaccine‐preventable diseases. The development of an appropriate vaccination strategy is required to decrease the risk of transmission in a hospital setting. (Source: Infect Control Hosp Epidemiol Latest Issue)
Source: Infect Control Hosp Epidemiol Latest Issue - September 10, 2009 Category: Epidemiology Tags: article Original Article Source Type: journals

[Current vaccination coverage and immunization gaps of children and adolescents in Germany.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Available data show increasing vaccination coverage of children and adolescents in recent years in Germany. Vaccination coverage of children against diphtheria, tetanus, polio and haemophilus influenzae Type b is high. Vaccination gaps exist for pertussis, hepatitis B and for the second measles, mumps and rubella doses. Coverage is still insufficient to achieve effective herd immunity and measles elimination. Data from the representative German Health Interview and Examination Survey for Children and Adolescents reveal that vaccination of infants is markedly delayed compared to recommendations of the German Standing Co...
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - September 9, 2009 Category: Global & Universal Authors: Reiter S, Poethko-Müller C Tags: Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz Source Type: journals

Measles mumps and rubella vaccine uptake fails to riseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Uptake of the MMR jab for measles mumps and rubella has failed to rise despite warnings from health experts. (Source: Telegraph Health)
Source: Telegraph Health - September 3, 2009 Category: Consumer Health News Source Type: news

Sudden deafness as a presenting symptom of chronic hepatitis B with acute exacerbationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report a case of chronic hepatitis B (CHB) with acute exacerbation that initially presented only as unilateral sudden SHL. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 2, 2009 Category: ENT & OMF Authors: Chi-Che Huang, Wei-Bin Lin, Po-Hung Chang, Kai-Chieh Chan, Ta-Jen Lee Tags: Case Reports Source Type: journals

Immunizations in Adult Patients with Systemic Sclerosisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, there is potential for serious illness and death in the underimmunization of high-risk patients, including those with SSc, and every effort should be made to ensure adequate protection through immunization. (Source: Annals of the New York Academy of Sciences)
Source: Annals of the New York Academy of Sciences - August 31, 2009 Category: Science Authors: Odile Launay, Loic Guillevin, Luc Mouthon Tags: Part IV. Infections and Autoimmunity Source Type: journals

Medical and Nursing Students with Suboptimal Protective Immunity against Vaccine‐Preventable Diseasesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. We have determined that there is a certain proportion of healthcare students who are susceptible to certain vaccine‐preventable diseases. The development of an appropriate vaccination strategy is required to decrease the risk of transmission in a hospital setting. (Source: Infect Control Hosp Epidemiol Latest Issue)
Source: Infect Control Hosp Epidemiol Latest Issue - August 26, 2009 Category: Epidemiology Tags: article Original Article Source Type: journals

Amino acid substitution at position 464 in the haemagglutinin-neuraminidase protein of a mumps virus Urabe strain enhanced the virus growth in neuroblastoma SH-SY5Y cells.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Mumps virus (MuV) infects various organs including central nervous system (CNS). However, the molecular basis of the neural cell specificity of MuV is not well understood. We found that the Hoshino vaccine strain rescued from cDNA replicated moderately in neuroblastoma SH-SY5Y cell line, while an Urabe strain (Ur89-250) isolated from a post-vaccination aseptic meningitis case replicated efficiently in the same cells. In order to examine the contribution of individual genes of Ur89-250 to the growth in SH-SY5Y cells, recombinant Hoshino vaccine strains in which each gene(s) was replaced with corresponding gene(s) of Ur8...
Source: Vaccine - August 23, 2009 Category: Allergy & Immunology Authors: Ninomiya K, Kanayama T, Fujieda N, Nakayama T, Komase K, Nagata K, Takeuchi K Tags: Vaccine Source Type: journals

Judge: Petitioners Failed To Demonstrate Causation Of Measles Vaccine To Autismemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
WASHINGTON, D.C. - Ruling that the "cornerstone" issue of whether Theresa Cedillo had persistent measles vaccine in her body was undermined by an unreliable laboratory, a U.S. Court of Claims judge on Aug. 6 affirmed a Vaccine Court special master's conclusion that the measles-mumps-rubella (MMR) vaccine did not cause the girl's autism (Theresa Cedillo, et al. v. Secretary, No. 98-916V, Fed. Clms.; 2009 U.S. Claims LEXIS 270; See July 2009, Page 4). Full story on lexis.com (Source: LexisNexis® Mealey's™ Thimerosal & Vaccines Legal News)
Source: LexisNexis® Mealey's™ Thimerosal & Vaccines Legal News - August 21, 2009 Category: Allergy & Immunology Source Type: info

Judge: Special Master Correctly Found Petition Had 'Two Cardinal Flaws'email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
WASHINGTON, D.C. - Saying the special master hearing the case had identified "two cardinal flaws" in the petitioners claims that the measles-mumps-rubella (MMR) vaccine caused their child's autism, a federal judge on July 24 affirmed the special master's denial of Vaccine Act benefits while acknowledging that the government's greater access to some of the evidence was "troubling" (Rolf and Angela Hazlehurst v. Secretary, No. 03-654V, Fed. Clms.; 2009 U.S. Claims LEXIS 252 Full story on lexis.com (Source: LexisNexis® Mealey's™ Thimerosal & Vaccines Legal News)
Source: LexisNexis® Mealey's™ Thimerosal & Vaccines Legal News - August 21, 2009 Category: Allergy & Immunology Source Type: info

Judge: Master's Denial Of Benefits To Autistic Child Entailed No Significant Erroremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
WASHINGTON, D.C. - Saying special masters' factual findings are "virtually unreviewable" and their conduct of proceedings are accorded great deference, a federal judge on Aug. 11 affirmed the denial of Vaccine Act compensation to a boy who claimed that the measles-mumps-rubella (MMR) vaccine caused his autism (Colten Snyder, et al. v. Secretary, No. 01-162V; Fed. Clms.; 2009 U.S. Claims LEXIS 280; See February 2009, Page 4). Full story on lexis.com (Source: LexisNexis® Mealey's™ Thimerosal & Vaccines Legal News)
Source: LexisNexis® Mealey's™ Thimerosal & Vaccines Legal News - August 21, 2009 Category: Allergy & Immunology Source Type: info

Investigation of a mumps outbreak among university students with two measles-mumps-rubella (MMR) vaccinations, Virginia, September-December 2006email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Following the clinical diagnosis of the first case of mumps on September 22, 2006 at the University of Virginia (UVA), 52 suspected cases were identified through active surveillance for mumps by the end of December 2006. Samples were collected from 47 students who presented with parotitis despite a documented history of two doses of measles, mumps, and rubella (MMR) vaccine. Six of 47 serum samples (13%) were positive for mumps IgM, and 46/47 specimens were positive for mumps IgG. Endpoint titration of acute phase serum samples from laboratory-confirmed cases did not provide evidence that elevated serum IgG is a consistent...
Source: Journal of Medical Virology - August 19, 2009 Category: Virology Authors: J.S. Rota, J.C. Turner, M.K. Yost-Daljev, M. Freeman, D.M. Toney, E. Meisel, N. Williams, S.B. Sowers, L. Lowe, P.A. Rota, L.A. Nicolai, L. Peake, W.J. Bellini Tags: Research Article Source Type: journals

VistA Community Members Propose VistA Installation Specificationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A broad range of VistA community members with diverse VistA backgrounds have proposed VistA Standard Base specification release candidate 8. The proposed document is intended to guide installation of Veterans Affairs VistA system on Linux using the Free/Open Source GTM mumps compiler. The text and public comment can be found here under the auspices of the Liberty Health Software Foundation a 501 c3 corporation. (Source: GNU/Linux And Open Source Medical Software News)
Source: GNU/Linux And Open Source Medical Software News - August 12, 2009 Category: Information Technology Source Type: news

Bovine and porcine gelatin sensitivity in children sensitized to milk and meatemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
To the Editor: Gelatin is a protein derived from collagen, and it is obtained principally from cow and pig bones, hides, and fish skin. It is a common ingredient in foods such as jellies, sweets, yogurt, and frozen desserts. It is also found in lunch meats, and it is used extensively as clarifying agents in wine, juices, and other beverages. Bovine and porcine gelatins, in particular, also have numerous applications throughout the pharmaceutical industry as integral components in drug capsules, plasma expanders, and stabilizers in vaccines, including measles, mumps and rubella (MMR), varicella, yellow fever, rabies, and s...
Source: Journal of Allergy and Clinical Immunology - August 10, 2009 Category: Allergy & Immunology Authors: Jelena Bogdanovic, Neal A. Halsey, Robert A. Wood, Robert G. Hamilton Tags: Letters to the Editor Source Type: journals

Immunization Programs for Infants, Children, Adolescents, and Adults: Clinical Practice Guidelines by the Infectious Diseases Society of Americaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Clinical Infectious Diseases, Volume 0, Issue 0, Page 000, Latest Articles. Evidence‐based guidelines for immunization of infants, children, adolescents, and adults have been prepared by an Expert Panel of the Infectious Diseases Society of America (IDSA). These updated guidelines replace the previous immunization guidelines published in 2002. These guidelines are prepared for health care professionals who care for either immunocompetent or immunocompromised people of all ages. Since 2002, the capacity to prevent more infectious diseases has increased markedly for several reasons: new vaccines have been licensed (h...
Source: Clinical Infectious Diseases Latest Issue - August 6, 2009 Category: Infectious Diseases Tags: article IDSA GUIDELINES Source Type: journals

A combined measles, mumps, rubella and varicella vaccine (Priorix-Tetra): Immunogenicity and safety profile.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Priorix-Tetra (GlaxoSmithKline Biologicals) is a combined measles, mumps, rubella and varicella (MMRV) vaccine. Eight studies involving more than 3000 children were reviewed. Compared with co-administration of MMR (Priorix) and varicella (Varilrix) vaccines, the MMRV vaccine showed: similar immunogenicity, with immunity shown up to 3 years post-vaccination; a higher rate of fever after the first dose; a slight increase in mild local reactions after the second dose. This MMRV vaccine can be used either as a two-dose vaccine or as a second dose in children primed with separate MMR and/or varicella vaccines, offering a co...
Source: Vaccine - August 5, 2009 Category: Allergy & Immunology Authors: Czajka H, Schuster V, Zepp F, Esposito S, Douha M, Willems P Tags: Vaccine Source Type: journals