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Photoprotective activity of zirconia nanoparticles
Colloids Surf B Biointerfaces. 2021 Feb 18;202:111636. doi: 10.1016/j.colsurfb.2021.111636. Online ahead of print.ABSTRACTThe increasing incidence of diseases caused by the harmful effects of UV radiation in skin, predominantly skin cancer, induce the search for more efficient photoprotector agents. Nowadays, titanium dioxide (TiO2) and zinc oxide (ZnO) are the most widely used photoprotectors and therefore form the main components of commercially available sunscreens. Although the outstanding efficiency in absorbing and scattering UV radiation, mainly as nanoparticles, recent studies have raised concerns regarding the saf...
Source: Colloids and Surfaces - March 11, 2021 Category: Biotechnology Authors: Renata Guimar ães de Sá Tatiane Moraes Arantes Erenilda Ferreira de Macedo Lu ísa Molina Dona' Jeniffer C F Pereira Carolina Ramos Hurtado R Jose Varghese Oluwatobi Samuel Oluwafemi Dayane Batista Tada Source Type: research

Phytofabrication of Selenium Nanoparticles From Emblica officinalis Fruit Extract and Exploring Its Biopotential Applications: Antioxidant, Antimicrobial, and Biocompatibility
Conclusion The present study shows phytofabrication of SeNPs from aqueous fruit extract of E. officinalis by facile, green, economic, and eco-friendly approach. The aqueous fruit extract of E. officinalis was rich with phenolics, flavonoids, and tannins, and was found appropriate for biosynthesis of nanoparticles. The synthesized PF-SeNPs exhibited highly stable, negative charge, amorphous nature, spherical shape and nano-size. The PF-SeNPs has presented efficient bio-potential applications, i.e., antioxidant, antimicrobial, and biocompatibility. The PF-SeNPs has shown potent free radical scavenging activity and it was fo...
Source: Frontiers in Microbiology - April 29, 2019 Category: Microbiology Source Type: research

Alginate-enabled green synthesis of S/Ag < sub > 1.93 < /sub > S nanoparticles, their photothermal property and in-vitro assessment of their anti-skin-cancer effects augmented by a NIR laser
We report herein the design and synthesis of colloidally-stable S/Ag1.93S nanoparticles, their photothermal conversion properties and in vitro cytotoxicity toward A431 skin cancer cells under the excitation of a minimally-invasive 980 nm near-infrared (NIR) laser. Micron-sized S particles were first synthesized via acidifying Na2S2O3 using biocompatible sodium alginate as a surfactant. In the presence of AgNO3 and under rapid microwave-induced heating, alginate reduced AgNO3 to nascent Ag which reacted with molten S in situ to S/Ag1.93S nanoparticles. The nanoparticles were characterized using a combination of X-ray diffra...
Source: International Journal of Biological Macromolecules - January 18, 2022 Category: Biochemistry Authors: Wei Chuen Yoong Chui Fung Loke Joon Ching Juan Khatijah Yusoff Norhafizah Mohtarrudin Tetsu Tatsuma Ying Xu Teck Hock Lim Source Type: research

Alginate-enabled green synthesis of S/Ag(1.93)S nanoparticles, their photothermal property and in-vitro assessment of their anti-skin-cancer effects augmented by a NIR laser
We report herein the design and synthesis of colloidally-stable S/Ag1.93S nanoparticles, their photothermal conversion properties and in vitro cytotoxicity toward A431 skin cancer cells under the excitation of a minimally-invasive 980 nm near-infrared (NIR) laser. Micron-sized S particles were first synthesized via acidifying Na2S2O3 using biocompatible sodium alginate as a surfactant. In the presence of AgNO3 and under rapid microwave-induced heating, alginate reduced AgNO3 to nascent Ag which reacted with molten S in situ to S/Ag1.93S nanoparticles. The nanoparticles were characterized using a combination of X-ray diffra...
Source: Cancer Control - January 18, 2022 Category: Cancer & Oncology Authors: Wei Chuen Yoong Chui Fung Loke Joon Ching Juan Khatijah Yusoff Norhafizah Mohtarrudin Tetsu Tatsuma Ying Xu Teck Hock Lim Source Type: research

Alginate-enabled green synthesis of S/Ag < sub > 1.93 < /sub > S nanoparticles, their photothermal property and in-vitro assessment of their anti-skin-cancer effects augmented by a NIR laser
We report herein the design and synthesis of colloidally-stable S/Ag1.93S nanoparticles, their photothermal conversion properties and in vitro cytotoxicity toward A431 skin cancer cells under the excitation of a minimally-invasive 980 nm near-infrared (NIR) laser. Micron-sized S particles were first synthesized via acidifying Na2S2O3 using biocompatible sodium alginate as a surfactant. In the presence of AgNO3 and under rapid microwave-induced heating, alginate reduced AgNO3 to nascent Ag which reacted with molten S in situ to S/Ag1.93S nanoparticles. The nanoparticles were characterized using a combination of X-ray diffra...
Source: International Journal of Biological Macromolecules - January 18, 2022 Category: Biochemistry Authors: Wei Chuen Yoong Chui Fung Loke Joon Ching Juan Khatijah Yusoff Norhafizah Mohtarrudin Tetsu Tatsuma Ying Xu Teck Hock Lim Source Type: research

X-ray and MR Contrast Bearing Nanoparticles Enhance the Therapeutic Response of Image-Guided Radiation Therapy for Oral Cancer
CONCLUSIONS: Theranostic nanoparticles enable preprocedure radiotherapy planning, as well as enhance radiation treatment efficacy for head and neck tumors.PMID:37469184 | PMC:PMC10363893 | DOI:10.1177/15330338231189593
Source: Technology in Cancer Research and Treatment - July 20, 2023 Category: Cancer & Oncology Authors: Gayatri Sharma Mir Hadi Razeghi Kondelaji Guru P Sharma Christopher Hansen Abdul K Parchur Shayan Shafiee Jaidip M Jagtap Brian Fish Carmen Bergom Eric Paulson William A Hall Heather A Himburg Amit Joshi Source Type: research

Effective Anticancer Therapy by Combination of Nanoparticles Encapsulating Chemotherapeutic Agents and Weak Electric Current
In this study, we applied WEC to tumors and investigated the EPR effect with polyethylene glycol (PEG)-modified doxorubicin (DOX) encapsulated nanoparticles (DOX-NP) administered via intravenous injection into melanoma-bearing mice. The application of WEC resulted in a 2.3-fold higher intratumor accumulation of nanoparticles. WEC decreased the amount of connexin 43 in tumors while increasing its phosphorylation; therefore, the enhancing of intratumor delivery of DOX-NP is likely due to the opening of gap junctions. Furthermore, WEC combined with DOX-NP induced a significant suppression of tumor growth, which was stronger t...
Source: Biological and Pharmaceutical Bulletin - February 3, 2022 Category: Drugs & Pharmacology Authors: Anowara Khatun Mahadi Hasan Mahran Mohamed Abd El-Emam Tatsuya Fukuta Miyuki Mimura Riho Tashima Shintaro Yoneda Shintaro Yoshimi Kentaro Kogure Source Type: research