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Cancer: Hepatocellular Carcinoma
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Mitochondrial Toxicity of Cadmium Telluride Quantum Dot Nanoparticles in Mammalian Hepatocytes
There are an increasing number of studies indicating that mitochondria are relevant targets in nanomaterial-induced toxicity. However, the underlying mechanisms by which nanoparticles (NPs) interact with these organelles and affect their functions are unknown. The aim of this study was to investigate the effects of cadmium telluride quantum dot (CdTe-QD) NPs on mitochondria in human hepatocellular carcinoma HepG2 cells. CdTe-QD treatment resulted in the enlargement of mitochondria as examined with transmission electron microscopy and confocal microscopy. CdTe-QDs appeared to associate with the isolated mitochondria as dete...
Source: Toxicological Sciences - June 22, 2015 Category: Toxicology Authors: Nguyen, K. C., Rippstein, P., Tayabali, A. F., Willmore, W. G. Tags: Quantum Dot Nanoparticles and Mitochondrial Function Source Type: research
In vitro antioxidant, anticancer, anti-inflammatory, anti-diabetic and anti-Alzheimer potentials of innovative macroalgae bio-capped silver nanoparticles
Environ Sci Pollut Res Int. 2022 Apr 9. doi: 10.1007/s11356-022-20039-x. Online ahead of print.ABSTRACTThe antagonistic side effects of chemical medications led to the search for safe strategies such as biogenic agents. Correspondingly, this study aims to create biogenic, appropriate, auspicious and innovative therapeutic agents like Galaxaura elongata {GE}, Turbinaria ornata {TO} and Enteromorpha flexuosa {EF} macroalgae-based silver nanoparticles (Ag-NPs). The Ag+ reduction and the creation of Ag[GE]-NPs, Ag[TO]-NPs and Ag[EF]-NPs have been validated using UV-visible spectroscopy, Fourier transform infrared spectroscopy ...
Source: Environmental Science and Pollution Research International - April 9, 2022 Category: Environmental Health Authors: Manal N Abdel Azeem Osama M Ahmed Mohamed Shaban Khaled N M Elsayed Source Type: research
Coffee-Derived Exosome-Like Nanoparticles: Are They the Secret Heroes?
CONCLUSION: For the first time in the literature, coffee edible plant-derived exosome-like nanoparticles were identified. These nanoparticles may have therapeutic effects on chronic liver diseases. Experimental studies, therefore, should be performed on disease models to demonstrate their efficacy.PMID:36262101 | DOI:10.5152/tjg.2022.21895
Source: The Turkish Journal of Gastroenterology - October 20, 2022 Category: Gastroenterology Authors: Murat Kantarc ıoğlu G ülşen Yıldırım P ınar Akpınar Oktar Serpil Yanbakan Zeynep B üşra Özer Deniz Yurtsever Sar ıca Serpil Ta şdelen Emel Bayrak Dilara Fatma Ak ın Balı Se çkin Öztürk Kamil Can Ak çalı Üstün Ezer Ahmet Emin K ürek Source Type: research
