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Nanoparticles On My Mind
By KIM BELLARD
Nanoparticles are everywhere! By that I mean, of course, that there seems to be a lot of news about them lately, particularly in regard to health and healthcare. But, of course, literally they could be anywhere and everywhere, which helps account for their potential, and their potential danger.
Let’s start with one of the more startling developments: a team at the University of Miami’s College of Engineering, led by Professor Sakhrat Khizroev, believes it has figured out a way to use nanoparticles to “talk” to the brain without wires or implants. They use “a novel clas...
Source: The Health Care Blog - March 23, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Health Tech Kim Bellard nanoparticles Source Type: blogs
Determination of the melting temperature of spherical nanoparticles in dilute solution as a function of their radius by exclusively using the small-angle X-ray scattering technique
In this investigation the dependence on radius of the melting temperature of dilute sets of spherical nanocrystals with wide radius distributions was determined by a novel procedure exclusively using the results of small-angle X-ray scattering (SAXS) measurements. This procedure is based on the sensitivity of the SAXS function to small and rather sharp variations in the size and electron density of nanocrystals at their melting temperature. The input for this procedure is a set of experimental SAXS intensity functions at selected q values for varying sample temperatures. In practice, the sample is heated from a minimum tem...
Source: Journal of Applied Crystallography - March 24, 2020 Category: Physics Authors: Kellermann, G. Pereira, F.L.C. Craievich, A.F. Tags: small-angle X-ray scattering SAXS melting nanoparticles thermal expansion size-dependent contraction research papers Source Type: research
Evaluation of the effect of guanabenz-loaded nanoparticles on chronic toxoplasmosis in mice
Exp Parasitol. 2023 Jan 12:108460. doi: 10.1016/j.exppara.2023.108460. Online ahead of print.ABSTRACTChronic toxoplasmosis which is positively correlated with many neuropsychiatric problems has no curative treatment till now; due to the resistant tissue cysts especially in the brain. In search of an effective treatment guanabenz-loaded polyethylene glycol poly lactic-co-glycolic acid (PEG-PLGA) nanoparticles was evaluated against chronic experimental toxoplasmosis. For this purpose, each mouse was infected with 10 cysts of Toxoplasma gondii (ME 49 strain). Treated mice received either guanabenz alone (5 mg/kg/day) in subgr...
Source: Experimental Parasitology - January 15, 2023 Category: Parasitology Authors: Wesam Moustafa Abdelhamid Elgendy Yusuf Ahmed Yusuf Haggag Kholoud Abd Allah El-Nouby Samy Ibrahim El-Kowrany Sirria Mostafa El Marhoumy Source Type: research
Rare-earth nanoparticles induce depression, anxiety-like behavior, and memory impairment in mice
Food Chem Toxicol. 2021 Jul 28:112442. doi: 10.1016/j.fct.2021.112442. Online ahead of print.ABSTRACTRare-earth nanoparticles have been widely studied for disease diagnosis, in vivo optical imaging, biosensing, and drug delivery. However, the effects of rare-earth nanoparticles on a central nervous system remain unclear. Here, we report that the continuous exposure to rare-earth nanoparticles in mice can cause behavioral alterations including cognitive deficits, anxiety, and depression-like behavior. Using an open-field test and a morris water maze, we showed that long-term exposure to rare-earth nanoparticles may lead to ...
Source: Food and Chemical Toxicology - July 31, 2021 Category: Food Science Authors: Caihou Lin Guifen Liu Yulong Huang Shunyi Liu Binghua Tang Source Type: research
Trends of Internet Search Volumes for Major Depressive Disorder Symptoms During the COVID-19 Pandemic in Korea: An Interrupted Time-Series Analysis
CONCLUSION: Our results reported the negative effect of COVID-19 preventive measures on public mental health in South Korea, especially for MDD symptoms. Moreover, the findings suggested the utility of Naver Trends as a feasible big data source to assess future mental health crises.PMID:35411728 | DOI:10.3346/jkms.2022.37.e108
Source: J Korean Med Sci - April 12, 2022 Category: General Medicine Authors: Jieun Kim Juhui Han Byung Chul Chun Source Type: research
Targeted Nursing Combined with Endoscopic Submucosal Injection of Carbon Nanoparticles in the Treatment of Colorectal Cancer
CONCLUSION: Targeted nursing alleviates the negative emotions of patients with colorectal cancer and improves their compliance, nursing satisfaction, daily living ability, and quality of life.PMID:35685723 | PMC:PMC9173991 | DOI:10.1155/2022/8663645
Source: Cancer Control - June 10, 2022 Category: Cancer & Oncology Authors: Libo Yin Source Type: research
Evaluation of the Therapeutic Effect of Curcumin-Conjugated Zinc Oxide Nanoparticles on Reserpine-Induced Depression in Wistar Rats
In conclusion, curcumin-conjugated zinc oxide nanoparticles demonstrate potent antidepressant effects, alleviating depressive-like behavior in rats. These findings support Zn(cur)O NPs as a promising therapeutic strategy for depression management, warranting further investigation and clinical validation.PMID:37713054 | DOI:10.1007/s12011-023-03849-z
Source: Biological Trace Element Research - September 15, 2023 Category: Biology Authors: Heba M Fahmy Fatmaalzahraa A Aboalasaad Ayman S Mohamed Fathi A Elhusseiny Yasser A Khadrawy Ahmed Elmekawy Source Type: research
