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Molecules, Vol. 27, Pages 6860: Antimicrobial Activity of Silver and Gold Nanoparticles Prepared by Photoreduction Process with Leaves and Fruit Extracts of Plinia cauliflora and Punica granatum
Courrol The increased number of resistant microbes generates a search for new antibiotic methods. Metallic nanoparticles have emerged as a new platform against several microorganisms. The nanoparticles can damage the bacteria membrane and DNA by oxidative stress. The photoreduction process is a clean and low-cost method for obtaining silver and gold nanoparticles. This work describes two original insights: (1) the use of extracts of leaves and fruits from a Brazilian plant Plinia cauliflora, compared with a well know plant Punica granatum, and (2) the use of phytochemicals as stabilizing agents in the photoreduction pr...
Source: Molecules - October 13, 2022 Category: Chemistry Authors: Marcia Regina Franzolin Daniella dos Santos Courrol Flavia Rodrigues de Oliveira Silva Lilia Coronato Courrol Tags: Article Source Type: research

Polymeric nanoparticles containing babassu oil: A proposed drug delivery system for controlled release of hydrophilic compounds
In this study, we developed and characterized particles containing babassu oil, solely or combined with sorbitan monostearate (Span® 60) or medium chain triglycerides (MCT) in the core to test different HLB and evaluated the encapsulation of a model hydrophilic molecule. Different techniques were used to characterize all formulations in terms of size and distribution, and in vitro drug release by dialysis technique was performed. The BBS was also characterized and presented 46,05 ± 1,11% and 15,38 ± 0,06% of lauric and myristic acid, respectively; saponification index of 248.87 ± 0.64 mg of KOH per gram of BBS, and no ...
Source: Chemistry and Physics of Lipids - April 20, 2023 Category: Lipidology Authors: Jo ão Vitor Raupp de Oliveira Pedro Leardin Silveira Gabriela Spingolon Gabriel Antonio Lopes Alves Fl ávia Pires Peña Tanira Alessandra Silveira Aguirre Source Type: research

Polymeric nanoparticles containing babassu oil: a proposed drug delivery system for controlled release of hydrophilic compounds
In this study, we developed and characterized particles containing babassu oil, solely or combined with sorbitan monostearate (Span® 60) or medium chain triglycerides (MCT) in the core to test different HLB and evaluated the encapsulation of a model hydrophilic molecule. Different techniques were used to characterize all formulations in terms of size and distribution, and in vitro drug release by dialysis technique was performed. The BBS was also characterized and presented 46,05 ± 1,11% and 15,38 ± 0,06 of lauric and myristic acid, respectively; saponification index of 248.87 ± 0.64mg of KOH per gram of BBS, and no ox...
Source: Chemistry and Physics of Lipids - April 18, 2023 Category: Lipidology Authors: Jo ão Vitor Raupp de Oliveira Pedro Leardin Silveira Gabriela Spingolon Gabriel Antonio Lopes Alves Fl ávia Pires Peña Tanira Alessandra Silveira Aguirre Source Type: research

Toxic Nanoparticles Coated with Antibiotics Safely Kill Drug Resistant Bacteria
A team of Brazilian scientists may have come up with a practical way of killing off resistant bacteria by targeting them with toxic silver-silica nanoparticles coated with an antibiotic. Since antibiotics don’t have the full punch to eliminat...
Source: Medgadget - July 11, 2017 Category: Medical Devices Authors: Editors Tags: Medicine Nanomedicine Source Type: blogs