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Total 5582 results found since Jan 2013.

Preparation of mucoadhesive methacrylated chitosan nanoparticles for delivery of ciprofloxacin
In this study, different experimental conditions including the polymer to TPP mass ratios, NaCl, and TPP concentration were changed to achieve unmodified and MeCHI nanoparticles with the smallest particle size and lowest polydispersity index. At 4:1 polymer /TPP mass ratio, both chitosan and MeCHI nanoparticles had the smallest size (133 ± 5 nm and 206 ± 9 nm, respectively). MeCHI nanoparticles were generally larger and slightly more polydisperse than the unmodified chitosan nanoparticles. Ciprofloxacin-loaded MeCHI nanoparticles had the highest encapsulation efficiency (69 ± 13 %) at 4:1 MeCHI /TPP mass ratio and 0.5 m...
Source: International Journal of Biological Macromolecules - May 26, 2023 Category: Biochemistry Authors: Renas Rzgar Jalal Twana Mohammed M Ways Mahmoud H Abu Elella Diyar Ahmed Hassan Vitaliy V Khutoryanskiy Source Type: research

Biomediated  synthesis, characterization, and biological applications of nickel oxide nanoparticles derived from Toona ciliata, Ficus carica and Pinus roxburghii
Bioprocess Biosyst Eng. 2021 Apr 5. doi: 10.1007/s00449-021-02528-4. Online ahead of print.ABSTRACTBiomediated ecofriendly method for the synthesis of nickel oxide nanoparticles using plants extracts (Toona ciliata, Ficus carica and Pinus roxburghii) has been reported. The nanoparticles so obtained were characterized by various techniques such as ultraviolet-visible, powder X-ray diffraction, Fourier transform infrared spectroscopy, attenuated total reflectance spectroscopy, scanning electron microscopy, transmission electron microscopy, energy dispersive X-ray spectroscopy, thermogravimetric analysis and fluorescence spec...
Source: Bioprocess and Biosystems Engineering - April 5, 2021 Category: Biomedical Engineering Authors: Azar Ullah Mirza Mohd Shoeb Khan Abdul Kareem Shahab A A Nami Shahnawaz Ahmad Bhat Abdulrahman Mohammad Paramjit Singh Nahid Nishat Source Type: research

The Antibacterial Effect of Ciprofloxacin Loaded Calcium Carbonate (CaCO < sub > 3 < /sub > ) Nanoparticles Against the Common Bacterial Agents of Osteomyelitis
Curr Microbiol. 2023 Apr 8;80(5):173. doi: 10.1007/s00284-023-03234-y.ABSTRACTThe present study aimed to investigate the biocompatibility, antibacterial/anti-biofilm effects of ciprofloxacin-loaded calcium carbonate (Cip- loaded CaCO3) nanoparticles against the common organisms responsible for osteomyelitis. The antibacterial and biofilm inhibitory activities were studied by determination of minimum inhibitory concentrations (MICs) and minimum biofilm inhibitory concentrations (MBICs), respectively. Hemolytic effects were determined for studying hemocompatibility. The SDS-PAGE method was used to study the interaction of Ci...
Source: Current Microbiology - April 8, 2023 Category: Microbiology Authors: Mohammad Yousef Memar Mohammad Ahangarzadeh Rezaee Mohammad Barzegar-Jalali Tooba Gholikhani Khosro Adibkia Source Type: research

Evaluation of Bactericidal Activity of Biologically Synthesised Silver Nanoparticles from Candida albicans in Combination with Ciprofloxacin
Publication date: 2015 Source:Materials Today: Proceedings, Volume 2, Issue 9, Part A Author(s): M. Amin Bhat, B.K. Nayak, Anima Nanda The aim and objective of present study was biosynthesis silver nanoparticles from fungi Candida albicans. The fungal biomass was challenged with 1mM AgNO3, which results in the colour change of the solution indicates the formation of Silver nanoparticles. These nanoparticles were further characterized by UV- visible spectroscopy which showed the absorption peak at 430nm. The FT-IR spectrum revealed the binding of protein to nanoparticles, which may be stabilized by the silver nanoparti...
Source: Materials Today: Proceedings - November 21, 2015 Category: Materials Science Source Type: research

Adsorption of ciprofloxacin in water using Fe3O4 nanoparticles formed at low temperature and high reactant concentrations in a rotating packed bed with co-precipitation
Publication date: 15 January 2020Source: Materials Chemistry and Physics, Volume 240Author(s): Chia-Chang Lin, Cheng-Yen LeeAbstractA rotating packed bed was used to form Fe3O4 nanoparticles at 25 °C with a rotational speed of 1800 rpm, flow rates of 0.5 L/min, and FeCl2, FeCl3, and NaOH concentrations of 0.15 mol/L, 0.3 mol/L, and 1.2 mol/L, respectively. The as-formed Fe3O4 nanoparticles had an average diameter of 9 nm, a BET specific surface area of 140 m2/g, and a saturation magnetization of 68 emu/g. The effectiveness of the as-formed Fe3O4 nanoparticles in adsorbing ciprofloxacin in water was evaluat...
Source: Materials Chemistry and Physics - September 26, 2019 Category: Materials Science Source Type: research

Preparation of biocompatible carboxymethyl chitosan nanoparticles for delivery of antibiotic drug.
CONCLUSION: This study shows that CCC NPs have stronger antibacterial activity against Escherichia coli than the free ciprofloxacin because they can easily be uptaken by cells. The obtained CCC NPs have promising prospect in drug delivery field. PMID: 23586023 [PubMed - indexed for MEDLINE]
Source: Biomed Res - November 12, 2013 Category: Research Authors: Zhao L, Zhu B, Jia Y, Hou W, Su C Tags: Biomed Res Int Source Type: research

Preparation and characterization of acetylated starch nanoparticles as drug carrier; Ciprofloxacin as a model.
The objective of this study was to characterize in-vitro the potential of acetylated corn starch (ACS) particles as a matrix for the delivery of ciprofloxacin (CFx). ACS was successfully synthesized and optimized by the reaction of native corn starch using acetic anhydride and acetic acid with low and high degrees of substitution (DS). The nanoprecipitation method was applied for the formation of the ACS-based nanoparticles, by the dropwise addition of water to acetone solution of ACS under stirring. The effects of acetylation and nanoprecipitation on the morphology and granular structure of ACS samples were examined by th...
Source: International Journal of Biological Macromolecules - February 15, 2016 Category: Biochemistry Authors: Mahmoudi Najafi SH, Baghaie M, Ashori A Tags: Int J Biol Macromol Source Type: research

Ciprofloxacin HCl-loaded calcium carbonate nanoparticles: preparation, solid state characterization, and evaluation of antimicrobial effect against Staphylococcus aureus.
Authors: Maleki Dizaj S, Lotfipour F, Barzegar-Jalali M, Zarrintan MH, Adibkia K Abstract Ciprofloxacin HCl-loaded calcium carbonate (CaCO3) nanoparticles were prepared via a w/o microemulsion method and characterized by dynamic light scattering, scanning electron microscopy, X-ray powder diffraction (XRPD) analysis, differential scanning calorimetry (DSC), and Fourier transform infrared spectroscopy (FTIR). The in vitro drug release profiles as well as antimicrobial effect against Staphylococcus aureus (S. aureus) were also evaluated. The antibacterial effect was studied using serial dilution technique to determin...
Source: Artificial Cells, Nanomedicine and Biotechnology - March 27, 2016 Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research

Re-evaluating the presumed superiority of amorphous nanoparticles over amorphous microscale solid dispersion in solubility enhancement of poorly soluble drugs.
Abstract The solubility enhancement afforded by amorphous drug nanoparticles was demonstrated in several studies to be superior to the traditional amorphization approach by microscale amorphous solid dispersion (or micro ASD in short). A closer look at these studies, however, revealed that they were performed using a very limited number of poorly-soluble drug models (i.e. itraconazole and cefuroxime). Herein we aimed to re-examine the solubility enhancement and physical stability of amorphous nanoparticles relative to that of the micro ASD using a different poorly-soluble drug model, i.e. ciprofloxacin (CIP). Two ...
Source: European Journal of Pharmaceutical Sciences - September 6, 2017 Category: Drugs & Pharmacology Authors: Lim LM, Tran TT, Cheow WS, Hadinoto K Tags: Eur J Pharm Sci Source Type: research

IJERPH, Vol. 16, Pages 2185: Optimization and Application of Bioflocculant Passivated Copper Nanoparticles in the Wastewater Treatment
hotla Nanotechnology offers a great opportunity for efficient removal of pollutants and pathogenic microorganisms in water. Copper nanoparticles were synthesized using a polysaccharide bioflocculant and its flocculation, removal efficiency, and antimicrobial properties were evaluated. The synthesized nanoparticles were characterized using thermogravimetry, UV-Visible spectroscopy, Fourier-transform infrared spectroscopy (FT-IR), powder X-ray diffraction, scanning electron microscope (SEM), and transmission electron microscope (TEM). The highest flocculation activity (FA) was achieved with the lowest concentration of co...
Source: International Journal of Environmental Research and Public Health - June 19, 2019 Category: Environmental Health Authors: Nkosinathi Goodman Dlamini Albertus Kotze Basson Viswanadha Srirama Rajasekhar Pullabhotla Tags: Article Source Type: research

Synthesis of Silver Nanoparticles Using Aqueous Extract of Medicinal Plants' (Impatiens balsamina and Lantana camara) Fresh Leaves and Analysis of Antimicrobial Activity.
Authors: Aritonang HF, Koleangan H, Wuntu AD Abstract Plant-mediated synthesis of nanomaterials has been increasingly gaining popularity due to its eco-friendly nature and cost-effectiveness. In the present study, we synthesized silver (Ag) nanoparticles using aqueous extracts of fresh leaves of Impatiens balsamina and Lantana camara medicinal plants as bioreducing agents. This method allowed the synthesis of nanoparticles, which was confirmed by ultraviolet-visible (UV-Vis) spectrophotometry and transmission electron microscopy (TEM). UV-Vis spectra and visual observation showed that the color of the fresh leaf ex...
Source: International Journal of Microbiology - July 31, 2019 Category: Microbiology Tags: Int J Microbiol Source Type: research

Large-scale aqueous synthesis of Cu(In,Ga)Se2 nanoparticles for photocatalytic degradation of ciprofloxacin
Dalton Trans., 2021, Advance Article DOI: 10.1039/D1DT03557F, PaperBruna F. Gon çalves, Pedro M. Martins, Alec P. LaGrow, Gabriela Botelho, Laura M. Salonen, Senentxu Lanceros-Méndez, Yury V. Kolen'ko Novel large-scale aqueous synthesis of CIGS phase-pure nanoparticles with tetragonal chalcopyrite structure, uniform chemical composition, and excellent optical properties. Nanoparticles for innovative photocatalytic degradation of CIP contaminant. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Dalton Trans. latest articles - November 14, 2021 Category: Chemistry Authors: Bruna F. Gon çalves Source Type: research