Filtered By:
Source: Molecules
This page shows you your search results in order of relevance.
Order by Relevance | Date
Total 2868 results found since Jan 2013.
Molecules, Vol. 21, Pages 1227: Molecular-Based Fluorescent Nanoparticles Built from Dedicated Dipolar Thienothiophene Dyes as Ultra-Bright Green to NIR Nanoemitters
Fluorescent Organic Nanoparticles (FONs), prepared by self-aggregation of dedicated dyes in water, represent a promising green alternative to the toxic quantum dots (QDs) for bioimaging purposes. In the present paper, we describe the synthesis and photophysical properties of new dipolar push-pull derivatives built from thieno[3,2-b]thiophene as a π-conjugated bridge that connects a triphenylamine moiety bearing various bulky substituents as electron-releasing moiety to acceptor end-groups of increasing strength (i.e., aldehyde, dicyanovinyl and diethylthiobarbiturate). All dyes display fluorescence properties in chlorofor...
Source: Molecules - September 13, 2016 Category: Chemistry Authors: Cristiano Mastrodonato Paolo Pagano Jonathan Daniel Michel Vaultier Mireille Blanchard-Desce Tags: Article Source Type: research
Molecules, Vol. 27, Pages 6860: Antimicrobial Activity of Silver and Gold Nanoparticles Prepared by Photoreduction Process with Leaves and Fruit Extracts of Plinia cauliflora and Punica granatum
Courrol
The increased number of resistant microbes generates a search for new antibiotic methods. Metallic nanoparticles have emerged as a new platform against several microorganisms. The nanoparticles can damage the bacteria membrane and DNA by oxidative stress. The photoreduction process is a clean and low-cost method for obtaining silver and gold nanoparticles. This work describes two original insights: (1) the use of extracts of leaves and fruits from a Brazilian plant Plinia cauliflora, compared with a well know plant Punica granatum, and (2) the use of phytochemicals as stabilizing agents in the photoreduction pr...
Source: Molecules - October 13, 2022 Category: Chemistry Authors: Marcia Regina Franzolin Daniella dos Santos Courrol Flavia Rodrigues de Oliveira Silva Lilia Coronato Courrol Tags: Article Source Type: research
Molecules, Vol. 20, Pages 6284-6298: Synthesis, Photophysical Characterization, and Photoinduced Antibacterial Activity of Methylene Blue-loaded Amino- and Mannose-Targeted Mesoporous Silica Nanoparticles
Over the last 20 years, the number of pathogenic multi-resistant microorganisms has grown steadily, which has stimulated the search for new strategies to combat antimicrobial resistance. Antimicrobial photodynamic therapy (aPDT), also called photodynamic inactivation, is emerging as a promising alternative to treatments based on conventional antibiotics. We have explored the effectiveness of methylene blue-loaded targeted mesoporous silica nanoparticles (MSNP) in the photodynamic inactivation of two Gram negative bacteria, namely Escherichia coli and Pseudomonas aeruginosa. For E. coli, nanoparticle association clearly red...
Source: Molecules - April 9, 2015 Category: Chemistry Authors: Oriol PlanasRoger Bresolí-ObachJaume NosThibault GallavardinRubén Ruiz-GonzálezMontserrat AgutSanti Nonell Tags: Article Source Type: research
Molecules, Vol. 26, Pages 3002: New O-Aryl-Carbamoyl-Oxymino-Fluorene Derivatives with MI-Crobicidal and Antibiofilm Activity Enhanced by Combination with Iron Oxide Nanoparticles
n Vasile
Adrian Ionuț Nicoară
Cornelia-Ioana Ilie
Anton Ficai
Carmen Limban
Antimicrobial resistance is one of the major public health threats at the global level, urging the search for new antimicrobial molecules. The fluorene nucleus is a component of different bioactive compounds, exhibiting diverse pharmacological actions. The present work describes the synthesis, chemical structure elucidation, and bioactivity of new O-aryl-carbamoyl-oxymino-fluorene derivatives and the contribution of iron oxide nanoparticles to enhance the desired biological activity. The antimicrobial activity assessed against three b...
Source: Molecules - May 18, 2021 Category: Chemistry Authors: Ilinca Margareta Vlad Diana Camelia Nu ță Robert Viorel Ancuceanu Miron Teodor Caproiou Florea Dumitrascu Ioana Cristina Marinas Mariana Carmen Chifiriuc Luminita Gabriela M ăruţescu Irina Zarafu Ioana Raluca Papacocea Bogdan Ștefan Vasile Adrian Ion Tags: Article Source Type: research
Molecules, Vol. 26, Pages 3288: In Search of Factors Determining Activity of Co3O4 Nanoparticles Dispersed in Partially Exfoliated Montmorillonite Structure
owski
The paper discusses a formation of Mt–PAA composite containing a natural montmorillonite structure partially exfoliated by poly(acrylic acid) introduced through intercalation polymerization of acrylic acid. Mt–PAA was subsequently modified by controlled adsorption of Co2+ ions. The presence of aluminosilicate packets (clay) and carboxyl groups (hydrogel) led to the deposition of significant amounts of Co2+ ions, which after calcination formed the Co3O4 spinel particles. The conditions of the Co2+ ions’ deposition (pH, volume and concentration of Co(NO3)2 solution, as well as a type of pH-controlling agent) ...
Source: Molecules - May 29, 2021 Category: Chemistry Authors: Anna Rokici ńska Tomasz Berniak Marek Drozdek Piotr Ku śtrowski Tags: Article Source Type: research
Molecules, Vol. 28, Pages 3228: Therapeutic Potential of Albumin Nanoparticles Encapsulated Visnagin in MDA-MB-468 Triple-Negative Breast Cancer Cells
iah
Pooi Ling Mok
Breast cancer is among the most recurrent malignancies, and its prevalence is rising. With only a few treatment options available, there is an immediate need to search for better alternatives. In this regard, nanotechnology has been applied to develop potential chemotherapeutic techniques, particularly for cancer therapy. Specifically, albumin-based nanoparticles are a developing platform for the administration of diverse chemotherapy drugs owing to their biocompatibility and non-toxicity. Visnagin, a naturally derived furanochromone, treats cancers, epilepsy, angina, coughs, and inflammatory illnes...
Source: Molecules - April 4, 2023 Category: Chemistry Authors: Abdullah Alsrhani Abozer Y. Elderdery Badr Alzahrani Nasser A. N. Alzerwi Maryam Musleh Althobiti Musaed Rayzah Bandar Idrees Ahmed M. E. Elkhalifa Suresh K. Subbiah Pooi Ling Mok Tags: Article Source Type: research
Molecules, Vol. 28, Pages 3931: Comparative Analysis of Stable Gold Nanoparticles Synthesized Using Sonochemical and Reduction Methods for Antibacterial Activity
This study focuses on the influence of synthetic methods on the aggregation stability and antibacterial activity of gold nanoparticles (NPs) prepared by using sodium citrate as a reducing and capping agent against Staphylococcus aureus (S. aureus). Gold NPs were synthesized using a simple and rapid sonochemical method and compared to gold NPs synthesized using a reduction method. The physicochemical features of gold NPs were characterized using UV-vis, XRD, TEM, and zeta potential, and the TEM results showed that the sonochemical method produced monodispersed spherical gold NPs with an average diameter of 18.5 nm, while th...
Source: Molecules - May 6, 2023 Category: Chemistry Authors: Mohammed Ali Dheyab Azlan Abdul Aziz Nazila Oladzadabbasabadi Alyaa Alsaedi Farhank Saber Braim Mahmood S. Jameel Asmeit Ramizy Mohammad Alrosan Ali Madi Almajwal Tags: Article Source Type: research
Molecules, Vol. 28, Pages 6424: Green Synthesis of Silver Nanoparticles Derived from Papaver rhoeas L. Leaf Extract: Cytotoxic and Antimicrobial Properties
Beylerli
In the last few decades, the search for metal nanoparticles as an alternative to cancer treatments and antibiotics has increased. In this article, the spectroscopic (ultraviolet–visible (UV-vis), electron-dispersing X-ray (EDX), and Fourier transform infrared (FT-IR)), microscopic (field emission scanning electron microscope (FE-SEM), transmission electron microscope (TEM), and atomic force microscope (AFM)), structural (X-ray diffractometer (XRD) and zetasizer), and analytic (thermogravimetric/differential thermal analyzer (TGA-DTA)) characterization of the silver nanoparticles (AgNPs) produced...
Source: Molecules - September 4, 2023 Category: Chemistry Authors: Polat İpek Re şit Yıldız Mehmet F ırat Baran Abdulkerim Hatipo ğlu Ay şe Baran Albert Sufianov Ozal Beylerli Tags: Article Source Type: research
Molecules, Vol. 21, Pages 731: Biologically Synthesized Gold Nanoparticles Ameliorate Cold and Heat Stress-Induced Oxidative Stress in Escherichia coli
Due to their unique physical, chemical, and optical properties, gold nanoparticles (AuNPs) have recently attracted much interest in the field of nanomedicine, especially in the areas of cancer diagnosis and photothermal therapy. Because of the enormous potential of these nanoparticles, various physical, chemical, and biological methods have been adopted for their synthesis. Synthetic antioxidants are dangerous to human health. Thus, the search for effective, nontoxic natural compounds with effective antioxidative properties is essential. Although AuNPs have been studied for use in various biological applications, explorati...
Source: Molecules - June 3, 2016 Category: Chemistry Authors: Xi-Feng ZhangWei ShenSangiliyandi Gurunathan Tags: Article Source Type: research
Molecules, Vol. 22, Pages 1553: Cytotoxic Evaluation of (2S)-5,7-Dihydroxy-6-prenylflavanone Derivatives Loaded PLGA Nanoparticles against MiaPaCa-2 Cells
o-Ramírez
The search for new alternatives for the prevention and treatment of cancer is extremely important to minimize human mortality. Natural products are an alternative to chemical drugs, since they are a source of many potential compounds with anticancer properties. In the present study, the (2S)-5,7-dihydroxy-6-prenylflavanone (semi-systematic name), also called (2S)-5,7-dihydroxy-6-(3-methyl-2-buten-1-yl)-2-phenyl-2,3-dihydro-4H-1-Benzopyran-4-one (CAS Name registered) (1) was isolated from Eysenhardtia platycarpa leaves. This flavanone 1 was considered as the lead compound to generate new cytotoxic derivatives...
Source: Molecules - September 15, 2017 Category: Chemistry Authors: Berenice Andrade-Carrera Beatriz Clares V éronique Noé Mireia Mallandrich Ana Calpena Mar ía García Mar ía Garduño-Ramírez Tags: Article Source Type: research
Molecules, Vol. 24, Pages 4629: Silica Coated Iron/Iron Oxide Nanoparticles as a Nano-Platform for T2 Weighted Magnetic Resonance Imaging
Montpeyó
Amiens
The growing concern over the toxicity of Gd-based contrast agents used in magnetic resonance imaging (MRI) motivates the search for less toxic and more effective alternatives. Among these alternatives, iron–iron oxide (Fe@FeOx) core-shell architectures have been long recognized as promising MRI contrast agents while limited information on their engineering is available. Here we report the synthesis of 10 nm large Fe@FeOx nanoparticles, their coating with a 11 nm thick layer of dense silica and functionalization by 5 kDa PEG chains to improve their biocompatibility. The nanomaterial...
Source: Molecules - December 16, 2019 Category: Chemistry Authors: Mathieu Coppel Respaud Nguyen Boutry Laurent Stanicki Henoumont Novio Lorenzo Montpey ó Amiens Tags: Article Source Type: research
Molecules, Vol. 25, Pages 830: Encapsulation of Variabilin in Stearic Acid Solid Lipid Nanoparticles Enhances Its Anticancer Activity in Vitro
In this study, the extraction of an Ircinia sp. sponge resulted in the isolation of an inseparable mixture of (7E,12E,20Z)-variabilin (1) and (7E,12Z,20Z)-variabilin (2) and structural assignment was established using standard 1D and 2D NMR experiments. The cytotoxic activity of the compound against three solid tumour cell lines displayed moderate anti-cancer activity through apoptosis, together with a general lack of selectivity among the cancer cell lines studied. Structural assignment and cytotoxic evaluation of variabilin was complicated and further aggravated by its inherent instability. Variabilin was therefore incor...
Source: Molecules - February 13, 2020 Category: Chemistry Authors: Mookho S. Lerata Sarah D ’Souza Nicole R.S. Sibuyi Admire Dube Mervin Meyer Toufiek Samaai Edith M. Antunes Denzil R. Beukes Tags: Article Source Type: research
Molecules, Vol. 21, Pages 1633: Enhanced Antimicrobial and Anticancer Activity of Silver and Gold Nanoparticles Synthesised Using Sargassum incisifolium Aqueous Extracts
A detailed, methodical approach was used to synthesise silver and gold nanoparticles using two differently prepared aqueous extracts of the brown algae Sargassum incisifolium. The efficiency of the extracts in producing nanoparticles were compared to commercially available brown algal fucoidans, a major constituent of brown algal aqueous extracts. The nanoparticles were characterised using TEM, XRD and UV/Vis spectroscopy and zeta potential measurements. The rate of nanoparticle formation was assessed using UV/Vis spectroscopy and related to the size, shape and morphology of the nanoparticles as revealed by TEM. The antiox...
Source: Molecules - December 1, 2016 Category: Chemistry Authors: Mokone Mmola Marilize Roes-Hill Kim Durrell John Bolton Nicole Sibuyi Mervin Meyer Denzil Beukes Edith Antunes Tags: Article Source Type: research
Molecules, Vol. 22, Pages 701: Silver Nanoparticles Mediated by Costus afer Leaf Extract: Synthesis, Antibacterial, Antioxidant and Electrochemical Properties
This study explored the use of aqueous leaf extract of Costus afer in the synthesis of silver nanoparticles (CA-AgNPs). The optical and structural properties of the resulting silver nanoparticles were studied using UV-visible spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM) and Fourier transform infra –red spectrophotometer (FTIR). TEM images of the silver nanoparticles confirmed the existence of monodispersed spherical nanoparticles with a mean size of 20 nm. The FTIR spectra affirmed the presence of phytochemicals from the Costus afer leaf extract on the surface of the silver nan...
Source: Molecules - April 29, 2017 Category: Chemistry Authors: Elias Elemike Omolola Fayemi Anthony Ekennia Damian Onwudiwe Eno Ebenso Tags: Article Source Type: research
Molecules, Vol. 24, Pages 4054: Encapsulation of Upconversion Nanoparticles in Periodic Mesoporous Organosilicas
Conclusions: upconversion nanoparticles were located on the surface of mesoporous nanorods obtained by hydrolysis polycondensation of bis(triethoxysilyl)ethylene, whereas encapsulation occurred with bis(triethoxysilyl)ethane. The later nanoparticles NaYF4: Yb3+-Er3+@Ethane or BaLuF5: Yb3+-Er3+@Ethane were promising for applications with cancer cell imaging or X-ray-computed tomography respectively.
Source: Molecules - November 8, 2019 Category: Chemistry Authors: Saher Rahmani Chiara Mauriello Jimenez Dina Aggad Daniel Gonz ález-Mancebo Manuel Oca ña Lamiaa M. A. Ali Christophe Nguyen Ana Isabel Becerro Nieto Nad ège Francolon Erwan Oliveiro Damien Boyer Rachid Mahiou Laurence Raehm Magali Gary-Bobo Jean-Olivie Tags: Article Source Type: research
