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Infectious Disease: Pandemics

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A review on recent trends of antiviral nanoparticles and airborne filters: special insight on COVID-19 virus
AbstractNovel corona virus (COVID-19) pandemic in the last 4  months stimulates the international scientific community to search for vaccine of antiviral agents suitable for in activating the virus inside and outside the human body. More than 4 million people globally are infected by the virus and about 300,000 dead cases until this moment. The ventilation a nd airborne filters are also investigated aiming to develop an efficient antiviral filtration technology. Human secretion of the infected person as nasal or saliva droplets goes as airborne and distributes the virus everywhere around the person. N95 and N98 filters ar...
Source: Air Quality, Atmosphere and Health - June 17, 2021 Category: Environmental Health Source Type: research

A potent virucidal activity of functionalized TiO < sub > 2 < /sub > nanoparticles adsorbed with flavonoids against SARS-CoV-2
Appl Microbiol Biotechnol. 2022 Aug 11:1-16. doi: 10.1007/s00253-022-12112-9. Online ahead of print.ABSTRACTThe coronavirus SARS-CoV-2 has caused a pandemic with > 550 millions of cases and > 6 millions of deaths worldwide. Medical management of COVID-19 relies on supportive care as no specific targeted therapies are available yet. Given its devastating effects on the economy and mental health, it is imperative to develop novel antivirals. An ideal candidate will be an agent that blocks the early events of viral attachment and cell entry, thereby preventing viral infection and spread. This work reports functionalized...
Source: Applied Microbiology and Biotechnology - August 11, 2022 Category: Microbiology Authors: Gabriela Le ón-Gutiérrez James Edward Elste Carlos Cabello-Guti érrez Cesar Mill án-Pacheco Mario H Mart ínez-Gómez Rafael Mej ía-Alvarez Vaibhav Tiwari Armando Mej ía Source Type: research

Potential of < em > Azadirachta indica < /em > as a Capping Agent for Antiviral Nanoparticles against SARS-CoV-2
Biomed Res Int. 2022 Sep 15;2022:5714035. doi: 10.1155/2022/5714035. eCollection 2022.ABSTRACTA rare type of pneumonia later on referred to as COVID-19 was reported in China in December 2019. Investigations revealed that this disease is caused by a coronavirus previously identified as SARS-CoV-2, and since then, it has become a global pandemic with new strains emerging rapidly as a result of genetic mutations. Various therapeutic options are being explored in order to eradicate this pandemic even though approved vaccine candidates are being currently rolled out globally. Most medicinal plant extracts have astonishing prope...
Source: Biomed Res - September 26, 2022 Category: Research Authors: Frank Eric Tatsing Foka Nanabi Manamela Steven Maluta Mufamadi Hazel Tumelo Mufhandu Source Type: research

A potent virucidal activity of functionalized TiO < sub > 2 < /sub > nanoparticles adsorbed with flavonoids against SARS-CoV-2
Appl Microbiol Biotechnol. 2022 Aug 11. doi: 10.1007/s00253-022-12112-9. Online ahead of print.ABSTRACTThe coronavirus SARS-CoV-2 has caused a pandemic with > 550 millions of cases and > 6 millions of deaths worldwide. Medical management of COVID-19 relies on supportive care as no specific targeted therapies are available yet. Given its devastating effects on the economy and mental health, it is imperative to develop novel antivirals. An ideal candidate will be an agent that blocks the early events of viral attachment and cell entry, thereby preventing viral infection and spread. This work reports functionalized tita...
Source: Applied Microbiology and Biotechnology - August 11, 2022 Category: Microbiology Authors: Gabriela Le ón-Gutiérrez James Edward Elste Carlos Cabello-Guti érrez Cesar Mill án-Pacheco Mario H Mart ínez-Gómez Rafael Mej ía-Alvarez Vaibhav Tiwari Armando Mej ía Source Type: research

Antiviral zinc oxide nanoparticles mediated by hesperidin and in silico comparison study between antiviral phenolics as anti-SARS-CoV-2
Colloids Surf B Biointerfaces. 2021 Mar 26;203:111724. doi: 10.1016/j.colsurfb.2021.111724. Online ahead of print.ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which caused the coronavirus (COVID-19), is the virus responsible for over 69,613,607 million infections and over 1,582,966 deaths worldwide. All treatment measures and protocols were considered to be supportive only and not curative. During this current coronavirus pandemic, searching for pharmaceutical or traditional complementary and integrative medicine to assist with prevention, treatment, and recovery has been advantageous. These phytop...
Source: Colloids and Surfaces - April 10, 2021 Category: Biotechnology Authors: Gouda H Attia Yasmine S Moemen Mahmoud Youns Ammar M Ibrahim Randa Abdou Mohamed A El Raey Source Type: research

Current status of silica-based nanoparticles as therapeutics and its potential as therapies against viruses
Antiviral Res. 2022 Dec 22:105488. doi: 10.1016/j.antiviral.2022.105488. Online ahead of print.ABSTRACTIn the past decade, interest in nanoparticles for clinical indications has been steadily gaining traction. Most recently, Lipid Nanoparticles (LNP) have been used successfully to construct the SARS-CoV-2 mRNA vaccines for rapid pandemic response. Similarly, silica is another nanomaterial which holds much potential to create nanomedicines against pathogens of interest. One major advantage of silica-based nanoparticles is its crystalline and highly ordered structure, which can be specifically tuned to achieve the desired pr...
Source: Antiviral Research - December 24, 2022 Category: Virology Authors: Danny Jian Hang Tng Jenny Guek Hong Low Source Type: research

Antiviral zinc oxide nanoparticles mediated by hesperidin and in silico comparison study between antiviral phenolics as anti-SARS-CoV-2
Colloids Surf B Biointerfaces. 2021 Mar 26;203:111724. doi: 10.1016/j.colsurfb.2021.111724. Online ahead of print.ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which caused the coronavirus (COVID-19), is the virus responsible for over 69,613,607 million infections and over 1,582,966 deaths worldwide. All treatment measures and protocols were considered to be supportive only and not curative. During this current coronavirus pandemic, searching for pharmaceutical or traditional complementary and integrative medicine to assist with prevention, treatment, and recovery has been advantageous. These phytop...
Source: Colloids and Surfaces - April 10, 2021 Category: Biotechnology Authors: Gouda H Attia Yasmine S Moemen Mahmoud Youns Ammar M Ibrahim Randa Abdou Mohamed A El Raey Source Type: research

Trends of Internet Search Volumes for Major Depressive Disorder Symptoms During the COVID-19 Pandemic in Korea: An Interrupted Time-Series Analysis
CONCLUSION: Our results reported the negative effect of COVID-19 preventive measures on public mental health in South Korea, especially for MDD symptoms. Moreover, the findings suggested the utility of Naver Trends as a feasible big data source to assess future mental health crises.PMID:35411728 | DOI:10.3346/jkms.2022.37.e108
Source: J Korean Med Sci - April 12, 2022 Category: General Medicine Authors: Jieun Kim Juhui Han Byung Chul Chun Source Type: research

The fear of COVID-19 and flourishing: the mediating role of search for meaning and presence of meaning
Curr Psychol. 2022 Nov 8:1-10. doi: 10.1007/s12144-022-03872-8. Online ahead of print.ABSTRACTPast researches have found that sense of control and meaning in life can act as a protective factor against fear of COVID-19 pandemic. The current study examined whether the search for meaning and the presence of meaning could mediate the link between fear of COVID-19 and flourishing. A total of 312 Iranians who were identified by snowball sampling were recruited as the subjects of the cross-sectional study. The participants gave their consent to complete the Meaning in Life Scale, Flourishing Scale, and Fear of COVID-19 Scale. Th...
Source: Current Psychology - November 21, 2022 Category: Psychiatry & Psychology Authors: Aman Sado Elemo Erg ün Kara Mehran Rostamzadeh Source Type: research