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The problem with providing education in the hospital environment is the persistent and unwarranted use of Internet Explorer which acts like a cubist Picasso converter to contort the website into a random series of incoherent text boxes Review of the old site highlighted a few functionality issues. One of the most frustrating elements of moving to a scalable mobile responsive design was the dropdown menus. We had far too much information crammed into an unpredictable space which was only intermittently visible…so they have been discarded with the new build. We have decided to run with ‘single menu tabs’ li...
Source: Life in the Fast Lane - November 11, 2013 Category: Emergency Medicine Doctors Authors: Mike Cadogan Tags: Blog News Featured Google Tips and Tricks blogging LITFL LITFL search Source Type: blogs

Facebook Graph Search in Medicine
Everyone has heard about the new Graph Search function on Facebook. It says “Want to start a book club or find a gym buddy? Connect with friends who like the same activities—and meet new people, too.” It will let Facebook users do searches by choosing different parameters (e.g. who goes to the same gym as me and is single). Well, many bloggers are optimistic about this launch and think it will be used in medicine too. I don’t think so and everyone should hope I’ll be right. It’s fun to identify friends in my community who I share the same multiple interests with (e.g. sci-fi and reading book...
Source: ScienceRoll - January 26, 2013 Category: Geneticists and Genetics Commentators Authors: Dr. Bertalan Meskó Tags: Facebook Health 2.0 Medical Search Medicine Medicine 2.0 Video Web 2.0 Source Type: blogs

Colorimetric detection of Pseudomonas aeruginosa by aptamer-functionalized gold nanoparticles
Appl Microbiol Biotechnol. 2022 Nov 24. doi: 10.1007/s00253-022-12283-5. Online ahead of print.ABSTRACTNovel rapid methodologies for the detection of bacteria have been recently investigated and applied. In hospital environments, infections by pathogens are very common and can cause serious health problems. Pseudomonas aeruginosa is one of the most common bacteria, which can grow in hospital equipment such as catheters and respirators. Even at low concentrations, it can cause severe infections as it is resistant to antibiotics and other treatments. Based on this subject's relevance, this work aimed to develop a colorimetri...
Source: Applied Microbiology and Biotechnology - November 23, 2022 Category: Microbiology Authors: Fernanda Raquel Wust Schmitz Karina Cesca Alexsandra Val ério D ébora de Oliveira Dachamir Hotza Source Type: research

More Nanoparticle Progress: MIT Designs ‘Pill of the Future’ Allowing Absorption of Drug-Carrying Nanoparticles Through Digestive Tract
Nanoparticles very well may be the future of healthcare as they are currently on the edge of medical research. Scientists across the globe are utilizing the unique properties of nanoparticles to develop new treatment techniques, as well as targeted d...
Source: Medgadget - December 3, 2013 Category: Technology Consultants Authors: Yona Gidalevitz Tags: Nanomedicine Source Type: blogs

Clot-building nanoparticles raise survival rate following blast trauma Read more: Clot-building nanoparticles raise survival rate following blast trauma
A type of artificial platelet being developed to help natural blood platelets form clots faster offers promise for saving the lives of soldiers, as well as victims of car crashes and other severe trauma.In preclinical tests led by a Case Western Reserve University researcher, the artificial platelets, called "hemostatic nanoparticles," when injected after blast trauma dramatically increased survival rates and showed no signs of interfering with healing or causing other complications weeks afterward."The nanoparticles have a huge impact on survival—not just in the short term, but in the long term," said Erin Lavik, an ass...
Source: Medical Hemostat - June 30, 2014 Category: Technology Consultants Authors: hemostatguy at gmail.com (hemostat guy) Source Type: blogs

Abstract B41: Gold nanoparticles based platforms for localized radiosensitization in cancer radiation therapy
The use of nanoparticles with high atomic (Z) number have been known to attenuate X-rays and the unique properties associated with gold nanoparticles makes them as potent radiosensitizers for enhancing Radiotherapy (RT) treatments. The interaction of high Z materials with the X-rays results in photoelectric absorption which leads to generation of photoelectrons. These low energy photoelectrons can deliver lethal energy in the close proximity. The success of cancer radiation therapy relies heavily on the effective delivery of radiation dose to the tumor site sparing the surrounding normal tissues. To overcome the limitation...
Source: Cancer Research - January 15, 2017 Category: Cancer & Oncology Authors: Rajiv Kumar, Wilfred Ngwa, Vinit Joshi, Sijumon Kunjachan, Ross Berbeco, Mike Makrigiorgos, Srinivas Sridhar Tags: Drug Delivery and Nanomedicine Source Type: research

Preparation of cellulose based wipes treated with antimicrobial and antiviral silver nanoparticles as novel effective high-performance coronavirus fighter
Int J Biol Macromol. 2021 Apr 14:S0141-8130(21)00830-8. doi: 10.1016/j.ijbiomac.2021.04.071. Online ahead of print.ABSTRACTCoronaviruses (CoV) are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV). We successful to prepare disinfectant cellulose-based wipes treated with antimicrobial and antiviral silver nanoparticles to be used for prevention of contamination and transmission of several pathogenic viruses and microbes to human in critical areas such as hospitals and healthcar...
Source: International Journal of Biological Macromolecules - April 17, 2021 Category: Biochemistry Authors: Tamer Hamouda Hassan M Ibrahim H H Kafafy H M Mashaly Nasser H Mohamed Nermin M Aly Source Type: research

Sugar Nanoparticles Reprogram Immune Cells to Help Destroy Tumors
This report is in line with a number of recent papers from the Weissleder Lab and labs around the world to reprogram the immune system to fight cancer. Cancer immunotherapy was ranked the biggest breakthrough in 2012 by the magazine Science, and team...
Source: Medgadget - June 11, 2018 Category: Medical Devices Authors: Ben Ouyang Tags: Nanomedicine Oncology Source Type: blogs

Silica nanoparticles embedded with water insoluble phthalocyanines for the photoinactivation of microorganisms
Antimicrobial resistance is a growing problem that complicates the treatment of infections acquired in the hospitals and in the community [1]. Therefore it is important to search for alternative therapeutic modalities [2]. Some modifications to the application of photodynamic therapy (PDT) for the treatment of cancer have been proposed for photokilling of microorganisms [3]. This approach, called photodynamic inactivation (PDI), is based on the preferential accumulation of the photosensitizer in the microbial cells.
Source: Photodiagnosis and Photodynamic Therapy - July 2, 2018 Category: Laser Surgery Authors: Estefania Baigorria, Eugenia Reynoso, M. Gabriela Alvarez, M. Elisa Milanesio, Edgardo N. Durantini Source Type: research

Comparing the Bacteriostatic Effects of Different Metal Nanoparticles Against Proteus vulgaris.
In this study, the antibacterial effects of silver, copper oxide, nickel oxide, and titanium dioxide nanoparticles were studied on Proteus vulgaris, as a bacterium involved in the resistant hospital infections. The capability of nanoparticles to inhibit the growth of bacteria was assessed via 9 different methods including cylinder, disk, and well-diffusion, spot test, MBC, MIC, liquid inhibitory action test, diffusion, and assessing the effects of nanoparticles on a 24-h culture. Based on the results, copper oxide and silver nanoparticles had high antibacterial effects on P. vulgaris in both liquid and solid cultures, resp...
Source: Current Microbiology - May 27, 2020 Category: Microbiology Authors: Charkhian H, Bodaqlouie A, Soleimannezhadbari E, Lotfollahi L, Shaykh-Baygloo N, Hosseinzadeh R, Yousefi N, Khodayar M Tags: Curr Microbiol Source Type: research

Biosynthesis and characterization with antimicrobial activity of TiO2 nanoparticles using probiotic Bifidobacterium bifidum.
Authors: Hkeem Ibrahem K, Ali FA, Abdulla Sorchee SM Abstract Bifidobacterium selectively colonizes the infants' intestinal tract, and the relevant coliform bacteria in adults are particularly beneficial because of their enhanced capability to prevent pathogens of gastro intestine by direct antimicrobial action and relieve infection, which led to their intensification, the antibacterial activities of titanium nanoparticles producing by some bacteria, makes them attractive as a new agent against pathogenic bacteria. In our present study, we used a probiotic bacteria Bifidobacterium bifidum which was isolated from th...
Source: Cellular and Molecular Biology - December 10, 2020 Category: Molecular Biology Tags: Cell Mol Biol (Noisy-le-grand) Source Type: research

Photothermal immunoassay for carcinoembryonic antigen based on the inhibition of cysteine-induced aggregation of gold nanoparticles by copper ion using a common thermometer as readout
Anal Chim Acta. 2021 Oct 9;1181:338929. doi: 10.1016/j.aca.2021.338929. Epub 2021 Aug 9.ABSTRACTThe dispersed gold nanoparticles (AuNPs) have weak photothermal effect in near-infrared (NIR) region. After the addition of cysteine, the AuNPs are aggregated due to the electrostatic interaction and then exhibited strong photothermal effect. At present of copper ion (Cu2+), the cysteine was catalytically oxidized into cystine, leading to the inhibition of the aggregation of AuNPs and the photothermal effect decreased. Based on this, a simple photothermal assay can be developed for Cu2+ detection using a common thermometer as re...
Source: Analytica Chimica Acta - September 24, 2021 Category: Chemistry Authors: Yingzhou Tao Weihao Shi Fang Luo Bin Qiu Zhenyu Lin Source Type: research