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Total 29661 results found since Jan 2013.

Recent advances in the use of metallic nanoparticles with antitumoral action.
Abstract The term cancer represents a set of more than 100 diseases that are caused due to an uncontrolled growth of cells; and their subsequent spread to the other tissues and organs of the body by a phenomenon, called 'metastasis'. According to the estimates provided by the World Health Organization (WHO), cancer is expected to account for about 10 million deaths per year by 2020, and 21 million cancer cases, which may lead to 13 million deaths by 2030, making cancer as the cause of highest mortality in contrast to other diseases. The search for potential therapeutics against cancer, which can reduce the side-ef...
Source: Current Medicinal Chemistry - February 13, 2018 Category: Chemistry Authors: da Silva PB, Machado RTA, Pironi AM, Alves RC, de Araujo PR, Dragalzew AC, Dalberto I, Chorilli M Tags: Curr Med Chem Source Type: research

Antimicrobial magnetic nanoparticles based-therapies for controlling infectious diseases
Publication date: Available online 16 November 2018Source: International Journal of PharmaceuticsAuthor(s): Gisele Regina Rodrigues, Carlos López-Abarrategui, Inés de la Serna Gómez, Simoni Campos Dias, Anselmo J. Otero-González, Octavio Luiz FrancoAbstractIn the last years, the antimicrobial resistance against antibiotics has become a serious health issue, arise as global threat. This has generated a search for new strategies in the progress of new antimicrobial therapies. In this context, different nanosystems with antimicrobial properties have been studied. Specifically, magnetic nanoparticles seem to be very attrac...
Source: International Journal of Pharmaceutics - November 17, 2018 Category: Drugs & Pharmacology Source Type: research

Phytofabrication of Selenium Nanoparticles From Emblica officinalis Fruit Extract and Exploring Its Biopotential Applications: Antioxidant, Antimicrobial, and Biocompatibility
Conclusion The present study shows phytofabrication of SeNPs from aqueous fruit extract of E. officinalis by facile, green, economic, and eco-friendly approach. The aqueous fruit extract of E. officinalis was rich with phenolics, flavonoids, and tannins, and was found appropriate for biosynthesis of nanoparticles. The synthesized PF-SeNPs exhibited highly stable, negative charge, amorphous nature, spherical shape and nano-size. The PF-SeNPs has presented efficient bio-potential applications, i.e., antioxidant, antimicrobial, and biocompatibility. The PF-SeNPs has shown potent free radical scavenging activity and it was fo...
Source: Frontiers in Microbiology - April 29, 2019 Category: Microbiology Source Type: research

Molecularly Imprinted Polymer Hydrogel Nanoparticles: Synthetic Antibodies for Cancer Diagnosis and Therapy
Chembiochem. 2021 Dec 6. doi: 10.1002/cbic.202100598. Online ahead of print.ABSTRACTCancer is a leading cause of death worldwide and according to the World Health Organization (WHO), accounted for 10 million deaths in 2020. Promising theranostic (therapy and diagnostic) agents in the treatment of cancer are nanomaterials, which have come to the forefront because of their small size approaching those of protein complexes in the human body, and of their easy functionalization giving access to nanocomposite materials with diverse functions (fluorescence, magnetic, stimuli-responsiveness…), and improved biocompatibility. Amo...
Source: Chembiochem - December 7, 2021 Category: Biochemistry Authors: Bernadette Tse Sum Bui Karsten Haupt Source Type: research

Metallic Nanoparticles: A New Frontier in the Fight Against Leishmaniasis
Curr Med Chem. 2022 Feb 25. doi: 10.2174/0929867329666220225111052. Online ahead of print.ABSTRACTLeishmaniasis is a cutaneous, mucocutaneous, or visceral parasitic disease caused by protozoa of the Leishmania genus. According to the World Health Organization, Leishmaniasis causes approximately 20-40 thousand deaths annually, and Brazil, India, and some countries in Africa are the most affected by this neglected disease. In addition to parasite's ability to evade the host's immune system, the incidence of vectors, the genetics of different hosts, and the large number of deaths are mainly due to failures in conventional tre...
Source: Current Medicinal Chemistry - February 28, 2022 Category: Chemistry Authors: Rhanoica Oliveira Guerra Jos é Rodrigues do Carmo Neto Tarc ísio de Albuquerque Martins Tha ís Soares Farnesi-de-Assunção Virmondes Rodrigues Junior Carlo Jos é Freire de Oliveira Anielle Christine Almeida Silva Marcos Vinicius da Silva Source Type: research

Determination and characterization of metal nanoparticles in clams and oysters.
Abstract With the extensive application of nanotechnology, metal nanoparticles (MNPs) have been widely used, thus are universally detected in the environment. This has caused increasingly concerns due to their toxicity and the potential health risks they pose to humans. In this work, the concentrations and particle size distributions of MNPs and concentrations of associated metal ionic species in shellfish seafood (clams and oysters) were investigated using single particle inductively coupled plasma mass spectrometry (sp-ICP-MS) and inductively coupled plasma mass spectrometry (ICP-MS). The MNPs in the clam and oy...
Source: Ecotoxicology and Environmental Safety - April 24, 2020 Category: Environmental Health Authors: Zhou Q, Liu L, Liu N, He B, Hu L, Wang L Tags: Ecotoxicol Environ Saf Source Type: research

Inhibitory effect of magnetic iron-oxide nanoparticles on the pattern of expression of lanosterol 14α-demethylase (ERG11) in fluconazole-resistant colonising isolate of Candida albicans
Fluconazole-resistant Candida albicans is a big scary reality. The authors assessed the antifungal effects of magnetic iron-oxide nanoparticles on fluconazole-resistant colonising isolate of C. albicans and determined the expression of ERG11 gene, protein sequence similarity and ergosterol content. C. albicans isolates were characterised and fluconazole resistance is recognised using World Health Organization's WHONET software. Susceptibility testing of magnetic iron-oxide nanoparticles against fluconazole-resistant colonising isolate of C. albicans was performed according to Clinical and Laboratory Standards Institute gui...
Source: IET Nanobiotechnology - July 24, 2020 Category: Nanotechnology Source Type: research

Chemodynamic features of nanoparticles: Application to understanding the dynamic life cycle of SARS-CoV-2 in aerosols and aqueous biointerfacial zones
Adv Colloid Interface Sci. 2021 Mar 4;290:102400. doi: 10.1016/j.cis.2021.102400. Online ahead of print.ABSTRACTWe review concepts involved in describing the chemodynamic features of nanoparticles and apply the framework to gain physicochemical insights into interactions between SARS-CoV-2 virions and airborne particulate matter (PM). Our analysis is highly pertinent given that the World Health Organisation acknowledges that SARS-CoV-2 may be transmitted by respiratory droplets, and the US Center for Disease Control and Prevention recognises that airborne transmission of SARS-CoV-2 can occur. In our theoretical treatment, ...
Source: Advances in Colloid and Interface Science - March 13, 2021 Category: Chemistry Authors: J érôme F L Duval Herman P van Leeuwen Willem Norde Raewyn M Town Source Type: research

Viruses, Vol. 11, Pages 1111: Virucidal Activity of Gold Nanoparticles Synthesized by Green Chemistry Using Garlic Extract
o-Ávila Measles virus (MeV) is a paramyxovirus that infects humans, principally children. Despite the existence of an effective and safe vaccine, the number of cases of measles has increased due to lack of vaccination coverage. The World Health Organization (WHO) reports that the number of cases worldwide multiplied fourfold between January and March 2019, to 112,000. Today, there is no treatment available for MeV. In recent years, it has been demonstrated that natural extracts (herbal or algal) with antiviral activity can also work as reducing agents that, in combination with nanotechnology, offer an innovative optio...
Source: Viruses - November 29, 2019 Category: Virology Authors: Mayra A. Mel éndez-Villanueva Karla Mor án-Santibañez Juan J. Mart ínez-Sanmiguel Ra úl Rangel-López Marco A. Garza-Navarro Cristina Rodr íguez-Padilla Diana G. Zarate-Trivi ño Laura M. Trejo- Ávila Tags: Article Source Type: research

Functionalized gold nanoparticles for the detection of arsenic in water.
Abstract Gold nanoparticles are attractive as sensing materials because of their size and shape are related with their optical properties. The color change produced by the aggregation of functionalized AuNPs allows the detection of arsenic at low levels. A simple, cheap and fast analytical procedure to perform arsenic determination using functionalized gold nanoparticles (AuNPs) and VIS spectrometry as a detection technique is studied. Three different synthesis procedures to obtain the AuNPs and two different functionalization modes were studied. AuNPs functionalized with GSH-DTT-CYs-PDCA were selected as the most...
Source: Talanta - December 2, 2013 Category: Chemistry Authors: Domínguez-González R, González Varela L, Bermejo-Barrera P Tags: Talanta Source Type: research