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Antiproliferative activity of Camellia sinensis mediated silver nanoparticles on three different human cancer cell lines
Conclusion: The superior activity of the silver nanoparticles may be due to its spherical shape and smaller particle size 10–30 nm as confirmed from NTA and TEM analysis. The data obtained in the study reveal the potent therapeutic value of biogenic silver nanoparticles.
Source: Journal of Cancer Research and Therapeutics - November 28, 2018 Category: Cancer & Oncology Authors: Anu Yadav Vijay D Mendhulkar Source Type: research

Molecules, Vol. 28, Pages 6424: Green Synthesis of Silver Nanoparticles Derived from Papaver rhoeas L. Leaf Extract: Cytotoxic and Antimicrobial Properties
Beylerli In the last few decades, the search for metal nanoparticles as an alternative to cancer treatments and antibiotics has increased. In this article, the spectroscopic (ultraviolet–visible (UV-vis), electron-dispersing X-ray (EDX), and Fourier transform infrared (FT-IR)), microscopic (field emission scanning electron microscope (FE-SEM), transmission electron microscope (TEM), and atomic force microscope (AFM)), structural (X-ray diffractometer (XRD) and zetasizer), and analytic (thermogravimetric/differential thermal analyzer (TGA-DTA)) characterization of the silver nanoparticles (AgNPs) produced...
Source: Molecules - September 4, 2023 Category: Chemistry Authors: Polat İpek Re şit Yıldız Mehmet F ırat Baran Abdulkerim Hatipo ğlu Ay şe Baran Albert Sufianov Ozal Beylerli Tags: Article Source Type: research

Application of gold nanoparticles for gastrointestinal cancer theranostics: a systematic review
Publication date: November 2015 Source:Nanomedicine: Nanotechnology, Biology and Medicine, Volume 11, Issue 8 Author(s): Mohan Singh, David C.C. Harris-Birtill, Sheraz R. Markar, George B. Hanna, Daniel S. Elson Gold nanoparticles (GNPs) are readily synthesised structures that absorb light strongly to generate thermal energy which induces photothermal destruction of malignant tissue. This review examines the efficacy, potential challenges and toxicity from in vitro and in vivo applications of GNPs in oesophageal, gastric and colon cancers. A systematic literature search of Medline, Embase, Web of Science and Cochran...
Source: Nanomedicine: Nanotechnology, Biology and Medicine - October 4, 2015 Category: Nanotechnology Source Type: research

Molecules, Vol. 25, Pages 830: Encapsulation of Variabilin in Stearic Acid Solid Lipid Nanoparticles Enhances Its Anticancer Activity in Vitro
In this study, the extraction of an Ircinia sp. sponge resulted in the isolation of an inseparable mixture of (7E,12E,20Z)-variabilin (1) and (7E,12Z,20Z)-variabilin (2) and structural assignment was established using standard 1D and 2D NMR experiments. The cytotoxic activity of the compound against three solid tumour cell lines displayed moderate anti-cancer activity through apoptosis, together with a general lack of selectivity among the cancer cell lines studied. Structural assignment and cytotoxic evaluation of variabilin was complicated and further aggravated by its inherent instability. Variabilin was therefore incor...
Source: Molecules - February 13, 2020 Category: Chemistry Authors: Mookho S. Lerata Sarah D ’Souza Nicole R.S. Sibuyi Admire Dube Mervin Meyer Toufiek Samaai Edith M. Antunes Denzil R. Beukes Tags: Article Source Type: research

Application of Gold Nanoparticles for Gastrointestinal Cancer Theranostics: A Systematic Review
Gold nanoparticles (GNPs) are readily synthesised structures that absorb light strongly to generate thermal energy which induces photothermal destruction of malignant tissue. This review examines the efficacy, potential challenges and toxicity from in vitro and in vivo applications of GNPs in oesophageal, gastric and colon cancers. A systematic literature search of Medline, Embase, Web of Science and Cochrane databases was performed using PRISMA guidelines. Two hundred and eighty-four papers were reviewed with sixteen studies meeting the inclusion criteria.
Source: Nanomedicine : Nanotechnology, Biology, and Medicine - June 23, 2015 Category: Nanotechnology Authors: Mohan Singh, David C.C. Harris-Birtill, Sheraz R. Markar, George B. Hanna, Daniel S. Elson Source Type: research

Facile synthesis of ZnO nanoparticles by Actinidia deliciosa fruit peel extract: Bactericidal, anticancer and detoxification properties
Environ Res. 2021 Jun 3:111433. doi: 10.1016/j.envres.2021.111433. Online ahead of print.ABSTRACTSynthesis of nanoparticles by eco-friendly method pulled an extensive concern worldwide due its biocompatibility and wide range of applications as catalysts, microbicidal agents, cancer treatment, sensors etc. Though different chemical methods available for preparation of ZnO nanoparticles, synthesis by utilizing plant material is an excellent substitute and green method as well. The present study describes preparation of ZnO nanoparticles by low-cost green synthetic way using Actinidia deliciosa (kiwi) fruit peel extract and i...
Source: Environmental Research - June 6, 2021 Category: Environmental Health Authors: Jie Li Yi Li Haisuo Wu Saraschandra Naraginti Yunbo Wu Source Type: research

Design and evaluation of albumin nanoparticles for the delivery of a novel β-tubulin polymerization inhibitor
CONCLUSIONS: The data support the potential use of albumin as a nanocarrier for CCI-001 in biological systems.PMID:34224665 | DOI:10.18433/jpps31877
Source: J Pharm Pharm Sci - July 5, 2021 Category: Drugs & Pharmacology Authors: Alessandra Spada Jaber Emami Foroughalsadat Sanaee Maral Aminpour Igor M Paiva Jack Tuszynski Afsaneh Lavasanifar Source Type: research