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Total 39172 results found since Jan 2013.
Silver ‐gold alloy nanoparticles biofabricated by fungal xylanases exhibited potent biomedical and catalytic activities
This study further em phasizes the significance of xylanases in nanobiotechnology as it has established the potential of xylanases to synthesize Ag‐AuNPs which is being reported for the first time.This article is protected by copyright. All rights reserved.
Source: Biotechnology Progress - May 2, 2019 Category: Biotechnology Authors: J.A Elegbede,
A Lateef,
M.A Azeez,
T.B Asafa,
T.A Yekeen,
I.C Oladipo,
S.H Abbas,
L.S Beukes,
E.B Gueguim ‐Kana Tags: RESEARCH ARTICLE Source Type: research
Scavenger Receptor-AI-Targeted Iron Oxide Nanoparticles for In Vivo MRI Detection of Atherosclerotic Lesions.
CONCLUSIONS: Collectively, our data provide several lines of evidence that SR-AI-targeted molecular imaging of USPIO-based contrast agents holds great promise for in situ detection of inflammatory plaques in manifest atherosclerosis.
PMID: 23744990 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - June 6, 2013 Category: Cardiology Authors: Segers FM, den Adel B, Bot I, van der Graaf LM, van der Veer E, Gonzalez W, Raynal I, de Winther M, Wodzig WK, Poelmann RE, van Berkel TJ, van der Weerd L, Biessen EA Tags: Arterioscler Thromb Vasc Biol Source Type: research
Biogenic synthesis, characterization and biological activity of lanthanum nanoparticles
In this study, biogenic lanthanum (La) nanoparticles were synthesized through ecofriendly green chemistry methodology. Mutingia calabura leaf extract was used for the synthesis of La nanoparticles. The synthesized La nanoparticles were characterized using FTIR, SEM and EDAX. Further, the nanoparticles were analysed for antibacterial activity, bacterial toxicity, antioxidant activity, blood compatibility and dye degradation efficiency. Well diffusion technique was used to study the antibacterial activity and antioxidant activity was evaluated using DPPH assay. Photocatalytic dye degradation study was carried out with Coomas...
Source: Materials Today: Proceedings - August 24, 2019 Category: Materials Science Source Type: research
Designing S100A9-Targeted Plant Virus Nanoparticles to Target Deep Vein Thrombosis
Biomacromolecules. 2021 Jun 1. doi: 10.1021/acs.biomac.1c00303. Online ahead of print.ABSTRACTThromboembolic conditions are a leading cause of death worldwide, and deep vein thrombosis (DVT), or occlusive venous clot formation, is a critical and rising problem that contributes to damage of vital organs, long-term complications, and life-threatening conditions such as pulmonary embolism. Early diagnosis and treatment are correlated to better prognosis. However, current technologies in these areas, such as ultrasonography for diagnostics and anticoagulants for treatment, are limited in terms of their accuracy and therapeutic...
Source: Biomacromolecules - June 1, 2021 Category: Biochemistry Authors: Jooneon Park Amy M Wen Huiyun Gao Matthew D Shin Daniel I Simon Yunmei Wang Nicole F Steinmetz Source Type: research
An Overview of the Latest Applications of Platelet-Derived Microparticles and Nanoparticles in Medical Technology 2010-2020
Curr Mol Med. 2021 Sep 28. doi: 10.2174/1566524021666210928152015. Online ahead of print.ABSTRACTToday, Platelets and platelet-derived nanoparticles and microparticles have found many applications in nanomedical technology. The results of our review study show that no article has been published in this field to review the current status of applications of these platelet derivatives so far. Therefore, in present study, our goal is to compare the applications of platelet derivatives and review their latest status between 2010 and 2020 to present the latest findings to researchers. A very interesting point about the role of p...
Source: Current Molecular Medicine - October 4, 2021 Category: Molecular Biology Authors: Tahereh Zadeh Mehrizi Source Type: research
Fungal xylanases-mediated synthesis of silver nanoparticles for catalytic and biomedical applications
This study has demonstrated the potential of xylanases to synthesise AgNPs which is to the best of our knowledge the first record of such. The present study underscores the relevance of xylanases in nanobiotechnology.
Source: IET Nanobiotechnology - August 17, 2018 Category: Nanotechnology Source Type: research
Direct delivery of plasmin using clot-anchoring thrombin-responsive nanoparticles for targeted fibrinolytic therapy
CONCLUSION: Considering that the very short circulation half-life (<1 second) of plasmin prevents its systemic use but also makes it safer without off-target drug effects, clot-targeted delivery of plasmin using CTNPs can enable safer and more efficacious fibrinolytic therapy.PMID:36696210 | DOI:10.1016/j.jtha.2022.11.037
Source: Thrombosis and Haemostasis - January 25, 2023 Category: Hematology Authors: Michael Sun M Hao Hao Pontius Stephanie Yang Tejal Pendekanti Shruti Raghunathan Jordan A Shavit Anirban Sen Gupta Source Type: research
Nanoparticles Help Platelets Stick Together to Stop Bleeding
Nanoparticles (green) help form clots in an injured liver. The researchers added color to the scanning electron microscopy image after it was taken. Credit: Erin Lavik, Ph.D.
At this week’s 252nd National Meeting & Exposition of the Americ...
Source: Medgadget - August 24, 2016 Category: Medical Equipment Authors: Editors Tags: Anesthesiology Cardiac Surgery Cardiology Critical Care Military Medicine Nanomedicine Source Type: blogs
Biomedical and Catalytic Applications of Gold and Silver-Gold Alloy Nanoparticles Biosynthesized Using Cell-Free Extract of Bacillus Safensis LAU 13: Antifungal, Dye Degradation, Anti-Coagulant and Thrombolytic Activities
This study investigated the green biosynthesis of gold (Au) and silver-gold alloy (Ag-Au) nanoparticles using cell-free extract of Bacillus safensis LAU 13 strain (GenBank accession No: KJ461434). The biosynthesized AuNPs and Ag-AuNPs were characterized using UV-Vis spectroscopy, Fourier-transform infrared spectroscopy, and transmission electron microscopy. Evaluation of the antifungal activities, degradation of malachite green, anti-coagulation of blood, and thrombolysis of human blood clot by the biosynthesized nanoparticles were investigated. The AuNPs and Ag-AuNPs had maximum absorbance at 561 and 545 nm, respectively....
Source: IEE Transactions on NanoBioscience - June 30, 2016 Category: Nanotechnology Source Type: research
Thrombolytic therapy based on fucoidan-functionalized polymer nanoparticles targeting P-selectin.
This study supports the hypothesis that fucoidan-nanoparticles improve the rt-PA efficiency. This work establishes the proof-of-concept of fucoidan-based carriers for targeted thrombolysis.
PMID: 29216534 [PubMed - as supplied by publisher]
Source: Biomaterials - November 29, 2017 Category: Materials Science Authors: Juenet M, Aid-Launais R, Li B, Berger A, Aerts J, Ollivier V, Nicoletti A, Letourneur D, Chauvierre C Tags: Biomaterials Source Type: research
Design Considerations and Assays for Hemocompatibility of FDA-Approved Nanoparticles
Semin Thromb Hemost DOI: 10.1055/s-0039-1688491Nanoparticles have numerous biomedical applications including, but not limited to, targeted drug delivery, diagnostic imaging, sensors, and implants for a wide range of diseases including cancer, diabetes, heart disease, and tuberculosis. Although the mode of delivery of the nanoparticles depends on the application and the disease, the nanoparticles are often in immediate contact with the systemic circulation either because of intravenous administration or their ability to enter the bloodstream with relative ease or their longer survival time in circulation. Once in circulatio...
Source: Seminars in Thrombosis and Hemostasis - August 11, 2019 Category: Hematology Authors: Saha, Amit K. Zhen, Min-Yi S. Erogbogbo, Folarin Ramasubramanian, Anand K. Tags: Review Article Source Type: research
The Protein Corona of Plant Virus Nanoparticles Influences their Dispersion Properties, Cellular Interactions, and In Vivo Fates
Biomolecules in bodily fluids such as plasma can adsorb to the surface of nanoparticles and influence their biological properties. This phenomenon, known as the protein corona, is well established in the field of synthetic nanotechnology but has not been described in the context of plant virus nanoparticles (VNPs). The interaction between VNPs derived from Tobacco mosaic virus (TMV) and plasma proteins is investigated, and it is found that the VNP protein corona is significantly less abundant compared to the corona of synthetic particles. The formed corona is dominated by complement proteins and immunoglobulins, the bindin...
Source: Small - February 8, 2016 Category: Nanotechnology Authors: Andrzej S. Pitek, Amy M. Wen, Sourabh Shukla, Nicole F. Steinmetz Tags: Full Paper Source Type: research
