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Next Phase of NIH Preprint Pilot Launching Soon
Last month, the National Library of Medicine (NLM)announced plans to extend its NIH Preprint Pilot in PubMed Central (PMC) and PubMed beyond COVID-19 to encompass all preprints reporting on NIH-funded research. The second phase of the pilot, launching later this month, will include preprints supported by an NIH award, contract, or intramural program and posted to aneligible preprint server on or after January 1, 2023.In preparation for the launch of this second phase, we have updated PMC and PubMed site features to help users of these databases incorporate the increased volume of preprints into their discovery workflows. S...
Source: PubMed Central News - January 10, 2023 Category: Databases & Libraries Source Type: news
Second Phase of the NIH Preprint Pilot Launched
Today, we are pleased to announce the launch of the second phase of the NIH Preprint Pilot with the addition of more than 700 new preprint records to PubMed Central (PMC) and PubMed. This second phase expands the scope of the Pilot to include preprints resulting from all NIH-funded research. Eligible preprints are those acknowledging direct support of an NIH award or authored by NIH staff and posted to bioRxiv, medRxiv, arXiv, or Research Square, on or after January 1, 2023. NLM will automatically include the full text of the preprint (as license terms allow) and associated citation information in PMC and PubMed, respectiv...
Source: PubMed Central News - January 30, 2023 Category: Databases & Libraries Source Type: news
Toxicity of silver nanoparticles on Endometrial Receptivity in Female Mice
Can J Physiol Pharmacol. 2021 Jul 20. doi: 10.1139/cjpp-2021-0094. Online ahead of print.ABSTRACTNanoparticles (NPs) have many toxic effects on fertility and can prevent successful implantation by affecting the maternal uterine tissue. Herein, by deploying thirty female NMRI mice, the effect of silver nanoparticles on the endometrium and implantation has been investigated. Using spherical silver nanoparticles of a diameter of 18-30 nm at doses of 2 and 4 mg/kg, mice in both groups were treated. Then, female mice mated with male mice. Endometrial tissue was extracted 4.5 days later. On the fourth day of pregnancy, the mice ...
Source: Canadian Journal of Physiology and Pharmacology - July 20, 2021 Category: Drugs & Pharmacology Authors: Marziyeh Ajdary Sahar Eghbali Vahid Pirhajati Mahabadi Fariborz Keyhanfar Rajender S Varma Source Type: research
Periostracum of bivalve mollusk shells for sampling engineered metal nanoparticles: A case study of silver-based nanoparticles in Canada's experimental lake
Chemosphere. 2022 May 12:134912. doi: 10.1016/j.chemosphere.2022.134912. Online ahead of print.ABSTRACTGiven the ability of engineered metal nanoparticles to be transformed in natural waters in unpredictable manners, various sampling methods must be developed. Here, we took a novel approach to collection silver nanoparticles (AgNPs) that involved the use of the intact periostracum, the outer proteinaceous organic layer, of freshwater unionid mussels Pyganodon sp. Eight adult mussels were collected in August 2019 from a small boreal lake (L222) at the International Institute for Sustainable Development - Experimental Lakes ...
Source: Chemosphere - May 15, 2022 Category: Chemistry Authors: Michael Zuykov Lauren Hayhurst Naoko Murakami-Sugihara Kotaro Shirai Graeme Spiers Michael Schindler Source Type: research
In-Vivo Anti-Diabetic and Wound Healing Effect of Antioxidant Gold Nanoparticles Synthesized Using Insulin Plant (Chamaecostus Cuspidatus)
ConclusionInterestingly the functionalization of gold nanoparticles as antidiabetic nanomaterials is achieved and the gold nanoparticles based drugs will be more active to interact with the targets if subjected to further studies.
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research
In Vivo Type 2 Diabetes and Wound-Healing Effects of Antioxidant Gold Nanoparticles Synthesized Using the Insulin Plant Chamaecostus cuspidatus in Albino Rats
ConclusionsThe use of gold nanoparticles as antidiabetes materials has been achieved. Further studies are required before gold nanoparticle–based drugs are more widely used.RésuméContexteLes nanoparticules d'or sont connues pour leurs nombreuses applications dans les domaines de la thérapeutique et du diagnostic.MéthodesLe présent article porte principalement sur la méthode de synthèse verte des nanoparticules d'or à partir de la poudre d'extrait de feuilles de la plante d'insuline Chamaecostus cuspidatus et sur la caractérisation de la synthèse médiée par la plante des nanoparticules d'or. De plus, nous avon...
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research
The Campylobacter fetus S layer provides resistance to photoactivated zinc oxide nanoparticles
In this study we assess the sensitivity of Campylobacter fetus, a Gram-negative bacterial pathogen of humans and animals, to ZnO nanoparticles and determine whether the S layer protects C. fetus from the antibacterial action of these nanoparticles. Broth and agar dilution assays revealed that ZnO nanoparticles at 100 μg/mL were bacteriocidal for C. fetus. Resazurin reduction assays confirmed the absence of metabolic activity, indicating that C. fetus cells had not entered into a viable but nonculturable state. Photoactivation of ZnO nanoparticles greatly enhanced their antibacterial activity, as evidenced by mi nimum bact...
Source: Canadian Journal of Microbiology - March 12, 2019 Category: Microbiology Authors: L.L. Graham S.E. Feero Source Type: research
