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Mapping research performance and hotspots on nanoparticles in cardiovascular diseases
This study aimed to comprehensively summarize the global scientific achievements of nanoparticles in cardiovascular diseases research. Articles on the application of nanoparticles in cardiovascular diseases published from 2002 to 2021 were retrieved from the science citation index expanded of the Web of Science Core Collection, and knowledge maps were generated by Cite Space, VOS viewer, and Hist Cite for further bibliometric analysis. A total of 4321 records were retrieved, and only reviews and articles were retained with a total of 4258 studies. The number of publications on nanoparticles in the cardiovascular field has ...
Source: Atherosclerosis - April 14, 2023 Category: Cardiology Authors: Dan Yin Mi Li Ping Xiang Source Type: research

Biogenic Synthesis of Silver Nanoparticles Using Phyllanthus emblica Fruit Extract and Its Inhibitory Action Against the Pathogen Acidovorax oryzae Strain RS-2 of Rice Bacterial Brown Stripe
Conclusion In conclusion, this study clearly provides an economical, environmental friendly, and straightforward reproducible approach in AgNPs synthesis employing P. Emblica fruit extracts as a reducing, stabilizing, and capping agent. The biosynthesized AgNPs were characterized thoroughly by UV-Visible and Energy Dispersive X-Ray Spectroscopy, X-Ray diffraction, FTIR, TEM, HRTEM and SEM. The FTIR results found several phytochemicals responsible for the rapid reduction of ions, leading to AgNPs formation. Especially, hydroxyl groups oxidation of hydrolysate, which likely stimulated the formation of nanoparticles. In the ...
Source: Frontiers in Microbiology - April 25, 2019 Category: Microbiology Source Type: research

Mapping research performance and hotspots on nanoparticles in cardiovascular diseases
This study aimed to comprehensively summarize the global scientific achievements of nanoparticles in cardiovascular diseases research. Articles on the application of nanoparticles in cardiovascular diseases published from 2002 to 2021 were retrieved from the science citation index expanded of the Web of Science Core Collection, and knowledge maps were generated by Cite Space, VOS viewer, and Hist Cite for further bibliometric analysis. A total of 4321 records were retrieved, and only reviews and articles were retained with a total of 4258 studies. The number of publications on nanoparticles in the cardiovascular field has ...
Source: Atherosclerosis - April 14, 2023 Category: Cardiology Authors: Dan Yin Mi Li Ping Xiang Source Type: research

Inhibition of Murine Breast Cancer Metastases by Hydrophilic As4S4 Nanoparticles Is Associated With Decreased ROS and HIF-1 α Downregulation
Conclusion It was showed that e-As4S4 could alleviate the metastatic features of aggressive breast cancers through correcting the tumor microenvironment, which prolonged the survival of tumor-bearing mice, showing its important therapeutic implications to the anti-metastasis therapy for breast cancer. Ethics Statement Six-week-old, female BALB/c mice were bred at the Experimental Animal Center at the Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (Beijing, China) under specific pathogen-free conditions. All the animal experiments reported herein were carried out in compliance with the regulatio...
Source: Frontiers in Oncology - April 26, 2019 Category: Cancer & Oncology Source Type: research

Clot-building nanoparticles raise survival rate following blast trauma Read more: Clot-building nanoparticles raise survival rate following blast trauma
A type of artificial platelet being developed to help natural blood platelets form clots faster offers promise for saving the lives of soldiers, as well as victims of car crashes and other severe trauma.In preclinical tests led by a Case Western Reserve University researcher, the artificial platelets, called "hemostatic nanoparticles," when injected after blast trauma dramatically increased survival rates and showed no signs of interfering with healing or causing other complications weeks afterward."The nanoparticles have a huge impact on survival—not just in the short term, but in the long term," said Erin Lavik, an ass...
Source: Medical Hemostat - June 30, 2014 Category: Technology Consultants Authors: hemostatguy at gmail.com (hemostat guy) Source Type: blogs

Nanotechnology in Healthcare: Getting Smaller and Smarter
We are living at the dawn of the nanomedicine age. I believe that nanoparticles and nanodevices will soon operate as precise drug delivery systems, cancer treatment tools or tiny surgeons. Let me introduce you the brave, new world of nanotechnology in healthcare. Nanorobots having nanobreakfast with your red and white blood cells When I was a kid, one of my favorite TV series was a French animation, Il était un fois… la vie (1986). I found it fascinating how the creators imagined the human body as a construction where tiny cars floated through the human veins, grab-cranes worked on teeth and bacteria as tiny monsters tr...
Source: The Medical Futurist - November 3, 2016 Category: Information Technology Authors: nora Tags: Nanotechnology in Medicine cancer treatment drug delivery system future GC1 Healthcare Innovation nanodevices nanoparticles robotics wearables Source Type: blogs

Nanoparticles Deliver siRNA to Prevent Joint Damage, Hopefully Treat Osteoarthritis
As osteoarthritis wears away at joint cartilage, there are no available drugs to stop the process. Steroid injections help to reduce inflammation in the area, but they get washed away by the body in a short amount of time and the process continues. R...
Source: Medgadget - October 4, 2016 Category: Medical Equipment Authors: Editors Tags: Nanomedicine Source Type: blogs

Lipid Nanoparticles Deliver CRISPR/Cas9 into Organs with High Efficiency
Researchers at Tufts University and the Chinese Academy of Sciences have developed a new lipid nanoparticle which can deliver CRISPR/Cas9 gene editing tools into organs with high efficiency, suggesting that the system is promising for clinical applic...
Source: Medgadget - July 15, 2019 Category: Medical Devices Authors: Conn Hastings Tags: Genetics Source Type: blogs

New Nanoparticles Help Spinal Cords to Heal Following Injury
In this study, i.v. administered poly(lactide-coglycolide) nanoparticles were internalized by circulating monocytes and neutrophils, reprogramming these cells based on their physicochemical properties and not by an active pharmaceutical ingredient, t...
Source: Medgadget - July 19, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Nanomedicine Neurology Neurosurgery Rehab Source Type: blogs

Solar Autoclave Activated by Special Nanoparticles to Sterilize Medical Equipment Anywhere (VIDEO)
Proper medical care beyond disposable syringes requires sterilization of equipment and treatment of dangerous biological waste, but autoclaves that use high pressure steam can be expensive and require a good deal of power to operate. A team of engine...
Source: Medgadget - July 29, 2013 Category: Technology Consultants Authors: Editors Tags: etc. Public Health Source Type: blogs

Evaluation of the Antibacterial Effect of Silver Nanoparticles on Guided Tissue Regeneration Membrane Colonization--An in Vitro Study.
CONCLUSION: The incorporation of silver nanoparticles may be of value when controlling membrane-associated infection. Studies with different nanosilver particle sizes should be conducted to further evaluate the beneficial properties of nanosilver against periodontal pathogens. PMID: 26373223 [PubMed - in process]
Source: Journal of the International Academy of Periodontology - November 30, 2015 Category: Dentistry Tags: J Int Acad Periodontol Source Type: research

Heterosubtypic influenza protection elicited by double-layered polypeptide nanoparticles in mice Immunology and Inflammation
Influenza is a persistent threat to public health. Here we report that double-layered peptide nanoparticles induced robust specific immunity and protected mice against heterosubtypic influenza A virus challenges. We fabricated the nanoparticles by desolvating a composite peptide of tandem copies of nucleoprotein epitopes into nanoparticles as cores and cross-linking another...
Source: Proceedings of the National Academy of Sciences - August 14, 2018 Category: Science Authors: Lei Deng, Timothy Z. Chang, Ye Wang, Song Li, Shelly Wang, Shingo Matsuyama, Guoying Yu, Richard W. Compans, Jian-Dong Li, Mark R. Prausnitz, Julie A. Champion, Bao-Zhong Wang Tags: PNAS Plus Source Type: research

Unexpected intracellular biodegradation and recrystallization of gold nanoparticles Medical Sciences
Gold nanoparticles are used in an expanding spectrum of biomedical applications. However, little is known about their long-term fate in the organism as it is generally admitted that the inertness of gold nanoparticles prevents their biodegradation. In this work, the biotransformations of gold nanoparticles captured by primary fibroblasts were monitored...
Source: Proceedings of the National Academy of Sciences - January 6, 2020 Category: Science Authors: Alice Balfourier, Nathalie Luciani, Guillaume Wang, Gerald Lelong, Ovidiu Ersen, Abdelali Khelfa, Damien Alloyeau, Florence Gazeau, Florent Carn Tags: Physical Sciences Source Type: research

Differences of Search Engine Digital Footprints Between Podiatrists and Foot and Ankle Orthopaedic Surgeons: A Need to Join the Digital Era
DISCUSSION: Foot and ankle-related Internet search terms results are overwhelmingly composed of podiatry-oriented sites. Per provider, regional differences are demonstrated, with FAOS having more sites in urban areas only. FAOS scope-of-practice terms such as "ankle replacement" still retain greater engagement by FAOSs. Search engine optimization and saturation strategies should be considered.LEVEL OF EVIDENCE: Level 3 (observational study).PMID:36067461 | DOI:10.5435/JAAOS-D-22-00189
Source: The Journal of the American Academy of Orthopaedic Surgeons - September 6, 2022 Category: Orthopaedics Authors: Benjamin J Chiang Zeeshan Malik Logan Laubach Prem Minchu Alex Gu Marc D Chodos Source Type: research