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Nanoparticles On My Mind
By KIM BELLARD
Nanoparticles are everywhere! By that I mean, of course, that there seems to be a lot of news about them lately, particularly in regard to health and healthcare. But, of course, literally they could be anywhere and everywhere, which helps account for their potential, and their potential danger.
Let’s start with one of the more startling developments: a team at the University of Miami’s College of Engineering, led by Professor Sakhrat Khizroev, believes it has figured out a way to use nanoparticles to “talk” to the brain without wires or implants. They use “a novel clas...
Source: The Health Care Blog - March 23, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Health Tech Kim Bellard nanoparticles Source Type: blogs
The Three-Dimensional Job Search
When most nurse job-seekers are in the market for a new nursing position, their job search process can be somewhat one-dimensional. From my perspective, a three-dimensional job search strategy is generally much more effective. And when it comes to career development, it ' s the same thing. One-dimensionsality breeds one-dimensional results -- why not try something more powerful?The One-Dimensional Job SearchIn a one-dimensional job search process, it kind of looks like this: you get up in the morning, make a cup of coffee, eat breakfast, and open your computer. You then peruse job boards like Indeed and Monster looking for...
Source: Digital Doorway - November 6, 2017 Category: Nursing Tags: career career development career management careers healthcare careers job search nurse nurse career nurse careers nurses nursing nursing careers Source Type: blogs
FDA, Google met to discuss use of search to find adverse drug reactions
Google met with the FDA last month to discuss the possibility of the FDA using Google search data to learn about drug side effects, according to a report in Bloomberg, which spotted a public record of the meeting and secured additional information from an FDA spokesperson. The talk appears to have been an informal, early-stage discussion on […]
Source: mobihealthnews - July 16, 2015 Category: Information Technology Authors: Jonah Comstock Tags: Government/Regulation adverse drug reaction adverse event FDA FDA adverse event reporting Google Google search side effects Source Type: news
Everybody lies: how Google search reveals our darkest secrets
What can we learn about ourselves from the things we ask online? US data scientist Seth Stephens ‑Davidowitz analysed anonymous Google search results, uncovering disturbing truths about our desires, beliefs and prejudicesEverybody lies. People lie about how many drinks they had on the way home. They lie about how often they go to the gym, how much those new shoes cost, whether they read that book. They call in sick when they ’re not. They say they’ll be in touch when they won’t. They say it’s not about you when it is. They say they love you when they don’t. They say they’re happy while in the dumps. They say ...
Source: Guardian Unlimited Science - July 9, 2017 Category: Science Authors: Seth Stephens-Davidowitz Tags: Google Books Alphabet Technology Big data Search engines Internet Psychology Science Race issues World news Culture Source Type: news
Authorship Order in Medical Education Publications: In Search of Practical Guidance for the Community.
This study describes principles commonly applied to authorship order decisions within the medical education community and educators' opinions about the significance of authorship order. Approach: A questionnaire was developed to ascertain current practices related to authorship decisions. Sixteen items were rated in terms of frequency of actual use and the desirability of the practice using a 4-point rating scale: 1 (never), 2 (sometimes), 3 (often), and 4 (always). Additional questions addressed the perceived significance of authorship order. The last set of questions provided information about respondents' personal and c...
Source: Teaching and Learning in Medicine - December 15, 2018 Category: Universities & Medical Training Authors: Authorship Order in Medical Education Publications: In Search of Practical Guidance for the Community. Tags: Teach Learn Med Source Type: research
Finding the best-fit background function for whole-powder-pattern fitting using LASSO combined with tree search
A new linear function for modelling the background in whole-powder-pattern fitting has been derived by applying LASSO (least absolute shrinkage and selection operator) and the technique of tree search. The background function (BGF) consists of terms bnL(2 θ /180) − n/2 and bnH(1 − 2 θ /180) − n/2 for the low- and high-angle sides, respectively. Some variable parameters of the BGF should be fixed at zero while others should be varied in order to find the best fit for a given data set without inducing overfitting. The LASSO algorithm can automatically select the variables in linear regression analysis. Ho...
Source: Journal of Applied Crystallography - February 14, 2021 Category: Physics Authors: Toraya, H. Tags: background functions LASSO tree search least absolute shrinkage and selection operator whole-powder-pattern fitting X-ray powder diffraction research papers Source Type: research
Using Robots and Artificial Intelligence to Search for New Medicines
Courtesy of Dr. Adam Gormley.
Adam Gormley, Ph.D., describes himself as a creative and adventurous person—albeit, not creative in the traditional sense. “Science allows me to be creative; to me, it’s a form of art. I love being outdoors, going on sailing trips, and spending time adventuring with my family. Research is the same—it’s an adventure. My creative and adventurous sides have combined into a real love for science,” he says. Dr. Gormley currently channels his passion for science into his position as an assistant professor of biomedical engineering at Rutgers University in Piscataway, New Jersey.
Lea...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - May 24, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Cells Tools and Techniques Bioinformatics Computational Biology Medicines Profiles Source Type: blogs
Titanium dioxide nanoparticles induced reactive oxygen species (ROS) related changes of metabolomics signatures in human normal bronchial epithelial (BEAS-2B) cells
In conclusion, TiO2 NPs increased the level of the oxidative stress, which could contribute to the altered signature represented by lipid metabolism in BEAS-2B cells.PMID:35430233 | DOI:10.1016/j.taap.2022.116020
Source: Toxicology and Applied Pharmacology - April 17, 2022 Category: Toxicology Authors: Jiahe Zhang Jiaqi Shi Shuo Han Pai Zheng Zhangjian Chen Guang Jia Source Type: research
Mesoporous silica nanoparticles as a prospective and promising approach for drug delivery and biomedical applications.
CONCLUSION: Through approaching to this review, the researchers can be aware of many new synthetic methods, smart designs proposed in recent year and remained question of MSNs at present.
PMID: 30520373 [PubMed - as supplied by publisher]
Source: Current Cancer Drug Targets - December 5, 2018 Category: Cancer & Oncology Authors: Pu X, Li J, Qiao P, Li M, Wang H, Zong L, Yuan Q, Duan S Tags: Curr Cancer Drug Targets Source Type: research
Next Phase of NIH Preprint Pilot Launching Soon
Last month, the National Library of Medicine (NLM)announced plans to extend its NIH Preprint Pilot in PubMed Central (PMC) and PubMed beyond COVID-19 to encompass all preprints reporting on NIH-funded research. The second phase of the pilot, launching later this month, will include preprints supported by an NIH award, contract, or intramural program and posted to aneligible preprint server on or after January 1, 2023.In preparation for the launch of this second phase, we have updated PMC and PubMed site features to help users of these databases incorporate the increased volume of preprints into their discovery workflows. S...
Source: PubMed Central News - January 10, 2023 Category: Databases & Libraries Source Type: news
Second Phase of the NIH Preprint Pilot Launched
Today, we are pleased to announce the launch of the second phase of the NIH Preprint Pilot with the addition of more than 700 new preprint records to PubMed Central (PMC) and PubMed. This second phase expands the scope of the Pilot to include preprints resulting from all NIH-funded research. Eligible preprints are those acknowledging direct support of an NIH award or authored by NIH staff and posted to bioRxiv, medRxiv, arXiv, or Research Square, on or after January 1, 2023. NLM will automatically include the full text of the preprint (as license terms allow) and associated citation information in PMC and PubMed, respectiv...
Source: PubMed Central News - January 30, 2023 Category: Databases & Libraries Source Type: news
Multiplexed structured illumination super-resolution imaging with lifetime-engineered upconversion nanoparticles
Nanoscale Adv. 2021 Nov 2;4(1):30-38. doi: 10.1039/d1na00765c. eCollection 2021 Dec 21.ABSTRACTThe emerging optical multiplexing within nanoscale shows super-capacity in encoding information by using lifetime fingerprints from luminescent nanoparticles. However, the optical diffraction limit compromises the decoding accuracy and throughput of the nanoparticles during conventional widefield imaging. This, in turn, challenges the quality of nanoparticles to afford the modulated excitation condition and further retain the multiplexed optical fingerprints for super-resolution multiplexing. Here we report a tailor-made multiple...
Source: Adv Data - September 22, 2022 Category: Epidemiology Authors: Baolei Liu Jiayan Liao Yiliao Song Chaohao Chen Lei Ding Jie Lu Jiajia Zhou Fan Wang Source Type: research
Machine learning predicts ecological risks of nanoparticles to soil microbial communities
This study merged raw high-throughput sequencing (HTS) data sets generated from 365 soil samples to reveal the potential ecological effects of NPs on soil microbial community by means of metadata analysis and machine learning methods. Metadata analysis showed that treatment with nanoparticles did not have a significant impact on the alpha diversity of the microbial community, but significantly altered the beta diversity. Unfortunately, the abundance of several beneficial bacteria, such as Dyella, Methylophilus, Streptomyces, which promote the growth of plants, and improve pathogenic resistance, was reduced under the additi...
Source: Environmental Pollution - May 27, 2022 Category: Environmental Health Authors: Nuohan Xu Jian Kang Yangqing Ye Qi Zhang Mingjing Ke Yufei Wang Zhenyan Zhang Tao Lu W J G M Peijnenburg None Josep Penuelas Guanjun Bao Haifeng Qian Source Type: research
