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Infectious Disease: Hepatitis
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Sustainable and green trends in using plant extracts for the synthesis of biogenic metal nanoparticles toward environmental and pharmaceutical advances: A review
Environ Res. 2021 Jul 7:111622. doi: 10.1016/j.envres.2021.111622. Online ahead of print.ABSTRACTConventionally utilized physical and chemical routes for constructing nanoparticles are not eco-friendly. They are associated with many shortcomings like the requirement of specially designed equipment, templates, extremely high temperature, and pressure. Biosynthesis seems to be drawn unequivocal attention owing to its upsurge of applications in different fields like; energy, nutrition, pharmaceutical, and medicinal sciences. To harness the biological sources, the present review describes an environment-friendly route to gener...
Source: Environmental Research - July 10, 2021 Category: Environmental Health Authors: Vatika Soni Pankaj Raizada Pardeep Singh Hoang Ngoc Cuong Rangabhashiyam S Adesh Saini Reena V Saini Quyet Van Le Ashok Kumar Nadda Thi-Thu Le Van-Huy Nguyen Source Type: research
Antiviral zinc oxide nanoparticles mediated by hesperidin and in silico comparison study between antiviral phenolics as anti-SARS-CoV-2
Colloids Surf B Biointerfaces. 2021 Mar 26;203:111724. doi: 10.1016/j.colsurfb.2021.111724. Online ahead of print.ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which caused the coronavirus (COVID-19), is the virus responsible for over 69,613,607 million infections and over 1,582,966 deaths worldwide. All treatment measures and protocols were considered to be supportive only and not curative. During this current coronavirus pandemic, searching for pharmaceutical or traditional complementary and integrative medicine to assist with prevention, treatment, and recovery has been advantageous. These phytop...
Source: Colloids and Surfaces - April 10, 2021 Category: Biotechnology Authors: Gouda H Attia Yasmine S Moemen Mahmoud Youns Ammar M Ibrahim Randa Abdou Mohamed A El Raey Source Type: research
Dissolving Microneedle Arrays as a Hepatitis B Vaccine Delivery System Adjuvanted by APC-Targeted Poly (Lactic-co-Glycolic Acid) (PLGA) Nanoparticles
This study verifies the feasibility of soluble composited microneedles administration in hepatitis B immunization, and provides new ideas for the development and application of non-injectable vaccine delivery systems.PMID:36697935 | DOI:10.1208/s12249-022-02473-9
Source: AAPS PharmSciTech - January 25, 2023 Category: Drugs & Pharmacology Authors: Xiaoling Zheng Jiahuan Zhu Caihong Zheng Zeng Tan Zhonghua Ji Jin Tao Yunchun Zhao Zhuwa Ji Ying Hu Source Type: research
Investigation of novel HCV therapies: Boscia angustifalia & amp;Boscia senegalensis extracts loaded on galactosylated chitosan nanoparticles synthesized by eco-friendly method for HCV treatment
In this study, we have modified galactosylation by an eco-friendly method using l-ascorbic instead of hazardous reagents and we have loaded it with newly tested two Boscia extracts each in three different concentrations. The synthesized chitosan nanoparticles showed two dispersion peaks, at 196 ± 29 nm and 1.33 ± 0.36 μm, with a zeta potential of +3.3 ± 0.4mV with high stability in a range of 40.7 mV. The percentage of encapsulation of Boscia angustifalia extract was found to be 46.58 ± 1.33 % and for Boscia senegalensis extract was 9.77 ± 0.33 %. The release of Boscia angustifalia extract from the nanoparticles was ...
Source: International Journal of Biological Macromolecules - June 23, 2023 Category: Biochemistry Authors: Huda R M Rashdan Hend Okasha Maha M Salem Bothaina M Abd El-Hady Basma Ekram Source Type: research
Inhibitory effects of silver nanoparticles against adenovirus type 3 in vitro.
Abstract
Adenoviruses are associated with respiratory, ocular, or gastrointestinal disease. With various species and high morbidity, adenoviruses are increasingly recognized as significant viral pathogen among pediatric and immunocompromised patients. However, there is almost no specific drug for treatment. Silver nanoparticles are demonstrated to be virucidal against influenza A (H1N1) virus, human immunodeficiency virus and Hepatitis B virus. Currently, there is no data regarding whether the silver nanoparticles inhibit the adenovirus or not. The aim of this study is to investigate the effect of silver nanoparti...
Source: Journal of Virological Methods - July 22, 2013 Category: Virology Authors: Chen N, Zheng Y, Yin J, Li X, Zheng C Tags: J Virol Methods Source Type: research
The enhanced immune response of hepatitis B virus DNA vaccine using SiO2@LDH nanoparticles as an adjuvant.
Abstract
Various approaches have been used to improve systemic immune response to infectious disease or virus, and DNA vaccination has been demonstrated to be one of these effective ways to elicit protective immunity against pathogens. Our previous studies showed that layered double hydroxides (LDH) nanoparticles could be efficiently taken up by the MDDCs and had an adjuvant activity for DC maturation. To further enhance the immune adjuvant activity of LDH, core-shell structure SiO2@LDH nanoparticles were synthesized with an average diameter of about 210 nm. And its high transfection efficiency in vitro was demo...
Source: Biomaterials - October 4, 2013 Category: Materials Science Authors: Wang J, Zhu R, Gao B, Wu B, Li K, Sun X, Liu H, Wang S Tags: Biomaterials Source Type: research
Antiviral zinc oxide nanoparticles mediated by hesperidin and in silico comparison study between antiviral phenolics as anti-SARS-CoV-2
Colloids Surf B Biointerfaces. 2021 Mar 26;203:111724. doi: 10.1016/j.colsurfb.2021.111724. Online ahead of print.ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which caused the coronavirus (COVID-19), is the virus responsible for over 69,613,607 million infections and over 1,582,966 deaths worldwide. All treatment measures and protocols were considered to be supportive only and not curative. During this current coronavirus pandemic, searching for pharmaceutical or traditional complementary and integrative medicine to assist with prevention, treatment, and recovery has been advantageous. These phytop...
Source: Colloids and Surfaces - April 10, 2021 Category: Biotechnology Authors: Gouda H Attia Yasmine S Moemen Mahmoud Youns Ammar M Ibrahim Randa Abdou Mohamed A El Raey Source Type: research
Therapeutic application of nanoparticles in hepatitis diseases: a narrative review 2011-2021
Curr Pharm Biotechnol. 2022 Jul 27. doi: 10.2174/1389201023666220727141624. Online ahead of print.ABSTRACTPURPOSE: Hepatitis, an inflammation of the liver parenchyma, is a viral disease. Addressing the challenges of hepatitis is very important. Therefore, using nanoparticles (NPs) in solving the problems of hepatitis diagnosis and treatment can be considered as a promising approach. Novelty: To the best of our knowledge, there are few studies to review the most widely used and effective NPs in the field of hepatitis. A literature review was performed on the publications available on the subject matter from 2011 to 2021. Th...
Source: Current Pharmaceutical Biotechnology - July 27, 2022 Category: Biotechnology Authors: Tahereh Zadeh Mehrizi Mehdi Shafiee Ardestani Source Type: research
Biosynthesis of metallic nanoparticles using plant derivatives and their new avenues in pharmacological applications - An updated report
Publication date: Available online 8 December 2014 Source:Saudi Pharmaceutical Journal Author(s): Palaniselvam Kuppusamy , Mashitah M. Yusoff , Natanamurugaraj Govindan The field of nanotechnology mainly encompasses with biology, physics, chemistry and material sciences and it develops novel therapeutic nanosized materials for biomedical and pharmaceutical applications. The biological syntheses of nanoparticles are being carried out by different macro-microscopic organisms such as plant, bacteria, fungi, seaweeds and microalgae. The biosynthesized nanomaterials have been effectively controlling the various endemic diseas...
Source: Saudi Pharmaceutical Journal - December 11, 2014 Category: Drugs & Pharmacology Source Type: research
