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Infectious Disease: Parasitic Diseases

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Total 28144 results found since Jan 2013.

New Strategies in the Treatment of Plasmodium Berghei Based on Nanoparticles: A Systematic Review
In this study, English-language online literature was obtained from the databases Science Direct, PubMed, Scopus, Ovid, and Cochrane to conduct a systematic review. In the search, we used the keywords: (Plasmodium Berghei) AND (Malaria) AND (Parasitemia) AND (antimalarial activity) AND (nanoparticles) AND (Solid lipid NPS) AND (Nano lipid carriers) AND (Artemether) AND (Chloroquine) AND (intraperitoneal) AND (in vivo). Initially, a total of 160 studies were retrieved from the search. After removing duplicates, 80 studies remained. After reviewing the title and abstract of each study, 45 unrelated studies were eliminated. T...
Source: Current Pharmaceutical Biotechnology - January 4, 2023 Category: Biotechnology Authors: Pegah Shakib Abdolrazagh Marzban Omid Mardanshah Shirzad Fallahi Israr Ali Khan Mohammad Azarhazin Kourosh Cheraghipour Source Type: research

New strategies in the treatment of diseases caused by Acanthamoeba based on nanoparticles: a systematic review
CONCLUSION: This study showed that chlorhexidine and other plant metabolites loaded with silver and gold nanoparticles increase the anti-Acanthambae activity of these nanoparticles. However, green synthesized nanoparticles based on stabilization by plant gums, loaded with citrus fruits flavonoids hesperidin (HDN) and naringin (NRG), showed the best anti-Acanthambae effect. Nevertheless, further studies should be performed to determine their safety for human use.PMID:36372923 | DOI:10.2174/2772432818666221111155119
Source: Pharmacological Reviews - November 14, 2022 Category: Drugs & Pharmacology Authors: Pegah Shakib Hamed Kalani Muhammad Tahir Aleem Roghiyeh Faridnia Mustafa Zebardast Pour Kobra Moradpour Kourosh Cheraghipour Source Type: research

IJERPH, Vol. 15, Pages 1037: Clinical Efficacy Associated with Enhanced Antioxidant Enzyme Activities of Silver Nanoparticles Biosynthesized Using Moringa oleifera Leaf Extract, Against Cutaneous Leishmaniasis in a Murine Model of Leishmania major
In conclusion, treatment with silver nanoparticles biosynthesized using Moringa oleifera extract has higher and faster clinical efficacy than standard pentavalent antimonial treatment, probably by boosting the endogenous antioxidant activity.
Source: International Journal of Environmental Research and Public Health - May 22, 2018 Category: Environmental Health Authors: Manal El-khadragy Ebtesam M. Alolayan Dina M. Metwally Mohamed F. Serag El-Din Sara S. Alobud Nour I. Alsultan Sarah S. Alsaif Manal A. Awad Ahmed E. Abdel Moneim Tags: Article Source Type: research

Synergistic antimicrobial potential of essential oils in combination with nanoparticles: Emerging trends and future perspectives
Publication date: 15 March 2017 Source:International Journal of Pharmaceutics, Volume 519, Issues 1–2 Author(s): Mahendra Rai, Priti Paralikar, Priti Jogee, Gauravi Agarkar, Avinash P. Ingle, Marcos Derita, Susana Zacchino The development of resistance to different antimicrobial agents by bacteria, fungi, viruses, parasites, etc. is a great challenge to the medical field for the treatment of infections caused by them, and therefore, there is a pressing need to search for new and novel antimicrobials. The antimicrobial activity of essential oils and biogenic nanoparticles is well known. Recent studies have demonstrated t...
Source: International Journal of Pharmaceutics - January 15, 2017 Category: Drugs & Pharmacology Source Type: research

Diethyldithiocarbamate loaded in beeswax-copaiba oil nanoparticles obtained by solventless double emulsion technique promote promastigote death in vitro
Publication date: Available online 18 December 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Karin Luize Mazur, Paulo Emílio Feuser, Alexsandra Valério, Arthur Poester Cordeiro, Camila Indiani de Oliveira, João Paulo Assolini, Wander Rogério Pavanelli, Claudia Sayer, Pedro H.H. AraújoAbstractLeishmaniasis is considered a neglected tropical disease that represents a Public Health problem due to its high incidence. In the search of new alternatives for Leishmaniasis treatment diethyldithiocarbamate (DETC) has shown an excellent leishmanicidal activity and the incorporation into drug carrier systems, such ...
Source: Colloids and Surfaces B: Biointerfaces - December 25, 2018 Category: Biochemistry Source Type: research

In vitro anthelmintic effect of biologically synthesized silver nanoparticles on liver amphistome, Gigantocotyle explanatum.
Abstract In order to ensure global food security a rationale approach is required to control all those factors which directly or indirectly affect the food productivity. The neglected helminthic diseases alone are responsible for huge economic losses to the agrarian stakeholders. The problem is further compounded by the emerging drug resistance in flukes against the commonly used anthelmintics like triclabendazole. Therefore, the search for alternatives including the nano-based approaches has become a necessity to develop future control strategies. In the present study the effect of biologically synthesized silver...
Source: Experimental Parasitology - February 12, 2019 Category: Parasitology Authors: Rehman A, Ullah R, Uddin I, Zia I, Rehman L, Abidi SMA Tags: Exp Parasitol Source Type: research

Biogenic silver nanoparticles (AgNp-Bio) reduce Toxoplasma gondii infection and proliferation in HeLa cells, and induce autophagy and death of tachyzoites by apoptosis-like mechanism
Acta Trop. 2021 Jul 28:106070. doi: 10.1016/j.actatropica.2021.106070. Online ahead of print.ABSTRACTToxoplasma gondii is a protozoan parasite that can cause severe and debilitating diseases, especially in immunocompromised individuals. The available treatment is based on drugs that have low efficacy, high toxicity, several adverse effects, and need long periods of treatment. Thus, the search for therapeutic alternatives is urgently needed. Biogenic silver nanoparticles (AgNp-Bio) have been associated with several biological effects, as antiproliferative, pro-apoptotic, antioxidant, antiviral, antifungal, and antiprotozoal...
Source: Acta Tropica - July 31, 2021 Category: Infectious Diseases Authors: Raquel Arruda da Silva Sanfelice Bruna Taciane da Silva Bortoleti Fernanda Tomiotto-Pellissier Taylon Felipe Silva Larissa Rodrigues Bosqui Gerson Nakazato Pablo Menegon Castilho Luiz Daniel de Barros Jo ão Luis Garcia Danielle Lazarin-Bid óia Ivete Con Source Type: research