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Infectious Disease: Outbreaks
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Total 28392 results found since Jan 2013.
Isolation, biosynthesis and antimicrobial activity of gold nanoparticles produced with extracts of Anabaena spiroides
Bioprocess Biosyst Eng. 2021 Mar 11. doi: 10.1007/s00449-021-02544-4. Online ahead of print.ABSTRACTMultidrug-resistant (MDR) pathogenic bacteria have become dangerous in bringing sporadic outbreaks in public health and nosocomial spreads from the addition of antibacterials/antibiotics continually. Obviously, the pharmacy world is in search of antibacterials that would be invincible by the evolved bacteria. Green synthesis of gold-nanoparticles (AuNps) was focused on the use of aqueous chloroauric acid (HAuCl4) and cell-free aqueous extract of the N2-fixing cyanobacterium (blue-green alga) Anabaena spiroides collected from...
Source: Bioprocess and Biosystems Engineering - March 11, 2021 Category: Biomedical Engineering Authors: Chinmayee Priyadarshini Mandhata Chita Ranjan Sahoo Chandrika Saloni Mahanta Rabindra Nath Padhy Source Type: research
Anti-bacterial activity of Cymbopogon citratus nanoparticles against Vibrio species infecting aquatic organisms
This study focuses on utilizing the bioactive compounds of Cymbopogon citratus as they are rich in a variety of secondary metabolites which promotes growth, natural immune response and disease resistance against pathogenic bacteria in various ecosystems. In silico studies were performed to evaluate the binding potential of the bioactive compounds against targeted protein beta - lactamase in Vibrio parahaemolyticus and metallo - beta - lactamase in V. alginolyticus via molecular docking. Cymbopogon citratus nanoparticles (CcNps) were synthesized, characterized and toxicity studies were performed by using Vigna radiata, and ...
Source: Aquatic Toxicology - May 19, 2023 Category: Toxicology Authors: V Santhana Lakshmi S Ranjani S Hemalatha Source Type: research
Current perspectives of nanoparticles in medical and dental biomaterials
Publication date: May 2012 Source:Journal of Biomedical Research, Volume 26, Issue 3 Author(s): Ibrahim Mohamed Hamouda Nanotechnology is gaining tremendous impetus due to its capability of modulating metals into their nanosize, which drastically changes the chemical, physical and optical properties of metals. Nanoparticles have been introduced as materials with good potential to be extensively used in biological and medical applications. Nanoparticles are clusters of atoms in the size range of 1–100 nm. Inorganic nanoparticles and their nano-composites are applied as good antibacterial agents. Due to the outbreak of i...
Source: Journal of Biomedical Research - November 3, 2014 Category: Biochemistry Source Type: research
Layered protein nanoparticles containing influenza B HA stalk induced sustained cross-protection against viruses spanning both viral lineages
In this study, we generated structure-stabilized HA stalk antigens from influenza B and fabricated double-layered protein nanoparticles as universal influenza B vaccine candidates. In vitro studies found that the resulting protein nanoparticles were effectively taken up to activate dendritic cells. Nanoparticle immunization induced broadly reactive immune responses conferring robust and sustained cross-immune protection against influenza B virus strains of both lineages. The results reveal the potential of layered protein nanoparticles incorporated with structure-stabilized constant antigens as a universal influenza vaccin...
Source: Biomaterials - July 10, 2022 Category: Materials Science Authors: Yufeng Song Wandi Zhu Ye Wang Lei Deng Yao Ma Chunhong Dong Gilbert X Gonzalez Joo Kim Lai Wei Sang-Moo Kang Bao-Zhong Wang Source Type: research
Alginate Nanoparticles as a Promising Adjuvant and Vaccine Delivery System
In this study diphtheria toxoid loaded nanoparticles were prepared by ionic gelation technique and characterized with respect to size, zeta potential, morphology, encapsulation efficiency, release profile, and immunogenicity. Appropriate parameters (calcium chloride and sodium alginate concentration, homogenization rate and homogenization time) redounded to the formation of suitable nanoparticles with a mean diameter of 70±0.5 nm. The loading studies of the nanoparticles resulted in high loading capacities (>90%) and subsequent release studies showed prolong profile. The stability and antigenicity of ...
Source: Indian Journal of Pharmaceutical Sciences - October 14, 2013 Category: Drugs & Pharmacology Authors: F SareiN Mohammadpour DounighiH ZolfagharianP KhakiS Moradi Bidhendi Source Type: research
Bacterial metal nanoparticles to develop new weapons against bacterial biofilms and infections
Appl Microbiol Biotechnol. 2021 Jun 29. doi: 10.1007/s00253-021-11418-4. Online ahead of print.ABSTRACTThe widespread use of antibiotics has resulted in the outbreak and spread of antibiotic-resistant pathogens. Bacterial antibiotic resistance may develop at cellular and community levels. In the latter case, it is based on tolerance which implicates the shift from a free-living form of life (i.e., planktonic) to a sessile multi-stratified community (i.e., biofilm). Metal nanoparticles (MNPs) have been shown to be promising candidates as antimicrobial agents. MNPs are able to interact with and penetrate bacterial biofilms, ...
Source: Applied Microbiology and Biotechnology - June 29, 2021 Category: Microbiology Authors: Giuseppe Gallo Domenico Schillaci Source Type: research
Use of 2D and co-culture cell models to assess the toxicity of zein nanoparticles loading insect repellents icaridin and geraniol
Colloids Surf B Biointerfaces. 2022 May 13;216:112564. doi: 10.1016/j.colsurfb.2022.112564. Online ahead of print.ABSTRACTAfter the latest dengue and Zika outbreaks, the fight against mosquito vectors has become an emerging area of research. One tool for this combat is repellents; however, these products are composed of different toxic agents. Botanical compounds with repellent potential are an alternative; however these compounds are highly volatile. Thus, the present study aimed to synthesize zein-based polymeric nanoparticles as an efficient carrier system for the sustained release of the repellents icaridin and geranio...
Source: Colloids and Surfaces - May 24, 2022 Category: Biotechnology Authors: T Germano-Costa N Bilesky-Jos é M Guilger-Casagrande T Pasquoto-Stigliani C B Rog ério D C Abrantes C R Maruyama J L Oliveira L F Fraceto R Lima Source Type: research
Antimicrobial Efficacy of Poly (DL‐lactide‐co‐glycolide) (PLGA) Nanoparticles with Entrapped Cinnamon Bark Extract against Listeria monocytogenes and Salmonella typhimurium
This study consisted of synthesizing and characterizing PLGA nanoparticles loaded with CBE. These nanoparticles with controlled release characteristics, by virtue of their size and physico‐chemical properties, enhanced the absorption/contact of a CBE by the microorganism and consequently antimicrobial activity. The data presented in this study can aid the food industry in developing more efficient and effective application of antimicrobials.
Source: Journal of Food Science - March 6, 2013 Category: Food Science Authors: Laura E. Hill, T. Matthew Taylor, Carmen Gomes Tags: N: NANOSCALE FOOD SCIENCE, ENGINEERING, AND TECHNOLOGY Source Type: research
Evolution of a Search: The Use of Dynamic Twitter Searches During Superstorm Sandy
Conclusion
The most important lesson learned from Superstorm Sandy was the need for a dynamic and flexible monitoring process and strategy to understand and respond quickly to health needs in the areas impacted by Superstorm Sandy. Search strategies should change as frequently as the unfolding event. The inability to adapt to a changing situation ensures stale and stagnant terminology and search results. Twitter lists and Boolean searches should be used together to maximize situational awareness. The most important information comes from the impacted population, whether news, local government or local citizens. These are t...
Source: PLOS Currents Disasters - September 26, 2014 Category: Global & Universal Authors: Sara Harris Smith Source Type: research
Chemodynamic features of nanoparticles: Application to understanding the dynamic life cycle of SARS-CoV-2 in aerosols and aqueous biointerfacial zones
Adv Colloid Interface Sci. 2021 Mar 4;290:102400. doi: 10.1016/j.cis.2021.102400. Online ahead of print.ABSTRACTWe review concepts involved in describing the chemodynamic features of nanoparticles and apply the framework to gain physicochemical insights into interactions between SARS-CoV-2 virions and airborne particulate matter (PM). Our analysis is highly pertinent given that the World Health Organisation acknowledges that SARS-CoV-2 may be transmitted by respiratory droplets, and the US Center for Disease Control and Prevention recognises that airborne transmission of SARS-CoV-2 can occur. In our theoretical treatment, ...
Source: Advances in Colloid and Interface Science - March 13, 2021 Category: Chemistry Authors: J érôme F L Duval Herman P van Leeuwen Willem Norde Raewyn M Town Source Type: research
