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Total 102435 results found since Jan 2013.
Dietary flavonoids: Nano delivery and nanoparticles for cancer therapy
In conclusion, although human studies are needed, NPs obtained from food-derived flavonoids have promising anticancer effects in vivo.
Source: Seminars in Cancer Biology - August 25, 2019 Category: Cancer & Oncology Source Type: research
Mitigating effect of single or combined administration of nanoparticles of zinc oxide, chromium oxide, and selenium on genotoxicity and metabolic insult in fructose/streptozotocin diabetic rat model
Environ Sci Pollut Res Int. 2021 Apr 28:1-18. doi: 10.1007/s11356-021-14089-w. Online ahead of print.ABSTRACTThis research was intended to evaluate the antidiabetic effect of single or combined administration of nanoparticles of zinc oxide nanoparticles (ZnONPs), chromium oxide nanoparticles (Cr2O3NPs), and selenium nanoparticles (SeNPs), on genetic and metabolic insult in fructose/streptozotocin diabetic rat model. Type 2 diabetes mellitus was induced by feeding sixty adult male albino rats with a high fructose diet accompanied by a single i.p. injection of streptozotocin (STZ). The rats were divided into 6 groups (10 rat...
Source: Environmental Science and Pollution Research International - April 28, 2021 Category: Environmental Health Authors: Rasha M Hassan Mai Elsayed Tahany E Kholief Naglaa H M Hassanen Jehan A Gafer Yasser A Attia Source Type: research
Synthesis of Iron Nanoparticles Using Sargassum wightii Extract and Its Impact on Serum Biochemical Profile and Growth Response of Etroplus suratensis Juveniles
Biol Trace Elem Res. 2022 Apr 20. doi: 10.1007/s12011-022-03236-0. Online ahead of print.ABSTRACTThe present study focuses on the green synthesis of iron nanoparticles using plant extracts as reducing, capping, and stabilizing agents. Aqueous seaweed extracts with the addition of iron solution were mixed using a magnetic stirrer which resulted in a color change indicating the formation of iron nanoparticles. The iron nanoparticles were successfully synthesized using Sargassum wightii extract. The synthesized iron nanoparticles were characterized by UV-Vis spectrophotometer, Fourier transform infrared spectroscopy (FTIR), a...
Source: Biological Trace Element Research - April 21, 2022 Category: Biology Authors: Rakesh Nirmalkar E Suresh N Felix A Kathirvelpandian Mir Ishfaq Nazir Amit Ranjan Source Type: research
Exposure to lutein-loaded nanoparticles attenuates Parkinson's model-induced damage in Drosophila melanogaster: restoration of dopaminergic and cholinergic system and oxidative stress indicators
Chem Biol Interact. 2021 Mar 11:109431. doi: 10.1016/j.cbi.2021.109431. Online ahead of print.ABSTRACTParkinson's is a neurodegenerative disease, characterized by the loss of dopaminergic neurons, cholinergic alterations and oxidative damages. Lutein is widely known by its antioxidants properties. In the present study, we investigated whether lutein-loaded nanoparticles protects against locomotor damage and neurotoxicity induced by Parkinson's disease model in Drosophila melanogaster, as well as possible mechanisms of action. First, the nanoparticles were characterized by physicochemical methods, demonstrating that water a...
Source: Chemico-Biological Interactions - March 15, 2021 Category: Molecular Biology Authors: Eliana Jardim Fernandes Marcia R ósula Poetini Magna Sotelo Barrientos Vandreza Cardoso Bortolotto St ífani Machado Araujo Elize Aparecida Santos Musachio Amarilis Santos De Carvalho Fernanda Vit ória Leimann Odinei Hess Gon çalves Bruna Piaia Ramborg Source Type: research
Propolis nanoparticles relieved the impacts of glyphosate-induced oxidative stress and immunosuppression in Nile tilapia
In this study, propolis nanoparticles were shown to relieve the impacts of glyphosate-induced oxidative stress and immunosuppression in Nile tilapia. The control group was fed a basal diet and maintained in a glyphosate-free water (control). Simultaneously, the other three groups were exposed to sublethal concentrations of glyphosate (0.6 mg/L) and fed diets containing 0 and 10 g propolis and 10 g propolis nanoparticles for 4 weeks. Nile tilapia exposed to glyphosate for 2 and 4 weeks exhibited a significant increase in serum alanine aminotransferase, aspartate aminotransferase, urea, and creatinine values compared to the ...
Source: Environmental Science and Pollution Research International - October 31, 2021 Category: Environmental Health Authors: Afaf D Abdelmagid Alshaimaa M Said Eman A Abdel Gawad Sara A Shalaby Mahmoud A O Dawood Source Type: research
Effects of Zinc Oxide Nanoparticles on the Performance of Broiler Chickens Under Hot Climatic Conditions
This study aimed to investigate the effects of different levels of zinc oxide nanoparticles on broilers' performance, nutrient digestibility, carcass criteria, and blood biochemistry. A total of 120 1-day-old unsexed broiler chickens (Ross 308) were fed zinc oxide nanoparticles at different levels (0, 20, 40, or 60 mg/kg) in their diets. Each treatment included 6 replicate pens with 5 birds each. The experiment lasted 42 days. The brooding temperatures were 37.8 °C, 35.8 °C, and 29.9 °C during 1-10 days, 11-21 days, and 22-42 days of age, respectively. The results revealed that dietary supplementation of nanoparticles o...
Source: Biological Trace Element Research - January 8, 2022 Category: Biology Authors: Ahmed A A Abdel-Wareth Khaled R A Hussein Zienhom S H Ismail Jayant Lohakare Source Type: research
Toxicokinetics and toxicodynamics of plastic and metallic nanoparticles: A comparative study in shrimp
In this study, juvenile Pacific white shrimp Litopenaeus vannamei was exposed to two types of nanoparticles at environmentally relative low and high concentrations, i.e., 100 nm polystyrene nanoplastics (nano-PS) and titanium dioxide nanoparticles (nano-TiO2) via dietary exposure for 28 days. The systematic toxicological evaluation aimed to quantitatively compare the accumulation, excretion, and toxic effects of nano-PS and nano-TiO2. Our results demonstrated that both nanoparticles were ingested by L. vannamei with lower egestion of nano-TiO2 than nano-PS. Both nanoparticles inhibited the growth of shrimps, damaged tissue...
Source: Environmental Pollution - September 5, 2022 Category: Environmental Health Authors: Xiaopeng Zhu Jia Teng Elvis Genbo Xu Jianmin Zhao Encui Shan Chaofan Sun Qing Wang Source Type: research
β-carotene-loaded nanoparticles protect against neuromotor damage, oxidative stress, and dopamine deficits in a model of Parkinson's disease in Drosophila melanogaster
Comp Biochem Physiol C Toxicol Pharmacol. 2023 Mar 18:109615. doi: 10.1016/j.cbpc.2023.109615. Online ahead of print.ABSTRACTβ-carotene-loaded nanoparticles improves absorption by increasing bioavailability. The Drosophila melanogaster model of Parkinson's disease must be helpful in investigating potential neuroprotective effects. Four groups of four-day-old flies were exposed to: (1) control; (2) diet containing rotenone (500 μM); (3) β-carotene-loaded nanoparticles (20 μM); (4) β-carotene-loaded nanoparticles and rotenone for 7 days. Then, the percentage of survival, geotaxis tests, open field, aversive phototaxis a...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - March 20, 2023 Category: Biochemistry Authors: Nathalie Savedra Gomes Chaves Dieniffer Espinosa Janner Marcia R ósula Poetini Eliana Jardim Fernandes Francielli Polet de Almeida Elize Aparecida Santos Musachio Jocemara Corr êa Reginaldo Mustafa Munir Mustafa Dahleh Amarilis Santos de Carvalho Fernan Source Type: research
Dietary Effect of Probiotic and Prebiotic on Some Mucus Indices of Silver Carp (Hypophthalmichthys molitrix) Exposed to Silver Nanoparticles
This study aimed to investigate the effect of using Pediococcus acidilactici and Agaricus bisporus separately and in combination with silver carp's mucosal immune system indices and finally the possibility of reducing the toxicity of silver nanoparticles in silver carp. After calculating LC50, the sub-lethal toxicity test was performed to sub-lethal concentration of silver nanoparticles for 14 days. Fish skin mucus was collected in polyethylene bags containing 10 ml of 50 mM sodium chloride for future analysis. Results of skin mucosal indices activity showed significant changes in treatments fed with additives compared to ...
Source: Biological Trace Element Research - January 11, 2022 Category: Biology Authors: Paria Houshmand Aliakbar Hedayati Source Type: research
