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Recent applications of click chemistry for the functionalization of gold nanoparticles and their conversion to glyco-gold nanoparticles
Abstract Glycoscience, despite its myriad of challenges, promises to unravel the causes of, potential new detection methods for, and novel therapeutic strategies against, many disease states. In the last two decades, glyco-gold nanoparticles have emerged as one of several potential new tools for glycoscientists. Glyco-gold nanoparticles consist of the unique structural combination of a gold nanoparticle core and an outer-shell comprising multivalent presentation of carbohydrates. The combination of the distinctive physicochemical properties of the gold core and the biological function/activity of the carbohydrates makes gl...
Source: Beilstein Journal of Organic Chemistry - January 3, 2018 Category: Chemistry Authors: Beilstein Journal of Organic Chemistry - Syndicated Feeds Tags: azide – alkyne Huisgen cycloaddition carbohydrates click chemistry glyco-gold nanoparticles triazole Review Source Type: research

Optical detection of di- and triphosphate anions with mixed monolayer-protected gold nanoparticles containing zinc(II) – dipicolylamine complexes
Abstract Gold nanoparticles covered with a mixture of ligands of which one type contains solubilizing triethylene glycol residues and the other peripheral zinc(II)–dipicolylamine (DPA) complexes allowed the optical detection of hydrogenphosphate, diphosphate, and triphosphate anions in water/methanol 1:2 (v/v). These anions caused the bright red solutions of the nanoparticles to change their color because of nanoparticle aggregation followed by precipitation, whereas halides or oxoanions such as sulfate, nitrate, or carbonate produced no effect. The sensitivity of phosphate sensing depended on the nature of the anion...
Source: Beilstein Journal of Organic Chemistry - November 3, 2020 Category: Chemistry Authors: Beilstein Journal of Organic Chemistry - Syndicated Feeds Tags: chemosensor diphosphate gold nanoparticles optical sensing triphosphate Full Research Paper Source Type: research

A new and efficient methodology for olefin epoxidation catalyzed by supported cobalt nanoparticles
Abstract A new heterogeneous catalytic system consisting of cobalt nanoparticles (CoNPs) supported on MgO and tert-butyl hydroperoxide (TBHP) as oxidant is presented. This CoNPs@MgO/t-BuOOH catalytic combination allowed the epoxidation of a variety of olefins with good to excellent yield and high selectivity. The catalyst preparation is simple and straightforward from commercially available starting materials and it could be recovered and reused maintaining its unaltered high activity. Beilstein J. Org. Chem. 2021, 17, 519–526. doi:10.3762/bjoc.17.46
Source: Beilstein Journal of Organic Chemistry - February 22, 2021 Category: Chemistry Authors: Beilstein Journal of Organic Chemistry - Syndicated Feeds Tags: alkenes cobalt nanoparticles epoxides oxidation TBHP Full Research Paper Source Type: research

Strain Sensors: Highly Sensitive Strain Sensors Based on Molecules –Gold Nanoparticles Networks for High‐Resolution Human Pulse Analysis (Small 8/2021)
In article number2007593, Artur Ciesielski, Paolo Samor ì, and co‐workers report the fabrication of a highly sensitive and flexible strain sensor for human‐health and vibration monitoring. The strain sensor is based on gold nanoparticles network bridged by organic molecules where the highly flexible nature of the linkers connecting the gold nanopart icles makes it possible to achieve superior sensing performance.
Source: Small - February 24, 2021 Category: Nanotechnology Authors: Chang ‐Bo Huang, Yifan Yao, Verónica Montes‐García, Marc‐Antoine Stoeckel, Miriam Von Holst, Artur Ciesielski, Paolo Samorì Tags: Inside Front Cover Source Type: research

Role of Organic and Inorganic Nanoparticles in the Drug Delivery System for Hypertension Treatment: A Systematic Review
CONCLUSION: This review demonstrated the anti-hypertensive effects of some organic and inorganic nanoparticles alone or in combination with the available anti-hypertensives. We found that organic nanoparticles such as PGLA and chitosan can be considered as preferred options in nanomedicine for treating high blood pressure. The results also showed these nanoparticles displayed antihypertensive effects through some mechanisms such as sustained release forms via increasing bioavailability, increasing oral bioavailability and improving oral and non-oral absorption, counteracting excessive superoxide, decreasing blood pressure,...
Source: Current Cardiology Reviews - March 17, 2022 Category: Cardiology Authors: Nasrollah Moradifar Ali Asghar Kiani Atefe Veiskaramian Kimia Karami Source Type: research

The Potential of Chitosan in Nanomedicine: An Overview of the Cytotoxicity of Chitosan Based Nanoparticles
The unique properties and applications of nanotechnology in targeting drug delivery, cosmetics, fabrics, water treatment and food packaging have received increased focus the last two decades. The application of nanoparticles in medicine is rapidly evolving, requiring careful investigation of toxicity before clinical use. Chitosan, a derivative of the natural polysaccharide chitin, has become increasingly relevant in modern medicine because of its unique properties as a nanoparticle. Chitosan is already widely used as a food additive and in food packaging, bandages and wound dressings. Thus, with an increasing application w...
Source: Frontiers in Pharmacology - May 4, 2022 Category: Drugs & Pharmacology Source Type: research

Current progress and prospects of organic nanoparticles against bacterial biofilm
Adv Colloid Interface Sci. 2021 Jun 30;294:102475. doi: 10.1016/j.cis.2021.102475. Online ahead of print.ABSTRACTBiofilm plays a vital role in the pathogenicity and resistance of bacteria, and is an important problem to be settled urgently in the treatment of bacterial diseases. Exploring effective strategies to control bacterial biofilm has become a hot research topic. Compared to other measures, organic nanomaterials have shown greater prospects in overcoming the problems of bacterial biofilms due to their unique properties. In order to explore more effective organic nanomaterials against biofilms, we used relevant keywo...
Source: Advances in Colloid and Interface Science - July 19, 2021 Category: Chemistry Authors: Xinyao Li Dongmei Chen Shuyu Xie Source Type: research

Lessons from the history of inorganic nanoparticles for inhalable diagnostics and therapeutics
Adv Colloid Interface Sci. 2023 Apr 12;315:102903. doi: 10.1016/j.cis.2023.102903. Online ahead of print.ABSTRACTThe respiratory tract is one of the most accessible ones to exogenous nanoparticles, yet drug delivery by their means to it is made extraordinarily challenging because of the plexus of aerodynamic, hemodynamic and biomolecular factors at cellular and extracellular levels that synergistically define the safety and efficacy of this process. Here, the use of inorganic nanoparticles (INPs) for inhalable diagnostics and therapies of the lung is viewed through the prism of the history of studies on the interaction of ...
Source: Advances in Colloid and Interface Science - April 21, 2023 Category: Chemistry Authors: Vuk Uskokovi ć Source Type: research