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Total 41574 results found since Jan 2013.
A nanotechnology based strategy to increase the efficiency of cancer diagnosis and therapy: Folate conjugated gold nanoparticles.
CONCLUSION: This review identifies the important roles of F-AuNPs in current cancer researches which are undertaken worldwide. The findings of this review confirm that F-AuNP is a new theranostic agent which has great potentials for simultaneous cancer therapy and diagnosis.
PMID: 28799495 [PubMed - as supplied by publisher]
Source: Current Medicinal Chemistry - August 10, 2017 Category: Chemistry Authors: Beik J, Khademi S, Attaran N, Sarkar S, Shakeri-Zadeh A, Ghaznavi H, Ghadiri H Tags: Curr Med Chem Source Type: research
Optimization and characterization of Brimonidine tartrate nanoparticles-loaded in situ gel for the treatment of glaucoma
CONCLUSION: The incorporation of optimized BRT-PLGA-TPGS nanoparticles into a thermosensitivein situ gel matrix to improve precorneal residence time without causing eye irritation and also serve the sustained release of BRT through cornea for effective management of glaucoma.PMID:33844617 | DOI:10.1080/02713683.2021.1916037
Source: Current Eye Research - April 12, 2021 Category: Opthalmology Authors: Pankaj Kumar Sharma Meenakshi Kanwar Chauhan Source Type: research
Machine learning predicts ecological risks of nanoparticles to soil microbial communities
This study merged raw high-throughput sequencing (HTS) data sets generated from 365 soil samples to reveal the potential ecological effects of NPs on soil microbial community by means of metadata analysis and machine learning methods. Metadata analysis showed that treatment with nanoparticles did not have a significant impact on the alpha diversity of the microbial community, but significantly altered the beta diversity. Unfortunately, the abundance of several beneficial bacteria, such as Dyella, Methylophilus, Streptomyces, which promote the growth of plants, and improve pathogenic resistance, was reduced under the additi...
Source: Environmental Pollution - May 27, 2022 Category: Environmental Health Authors: Nuohan Xu Jian Kang Yangqing Ye Qi Zhang Mingjing Ke Yufei Wang Zhenyan Zhang Tao Lu W J G M Peijnenburg None Josep Penuelas Guanjun Bao Haifeng Qian Source Type: research
Enhanced resonance energy transfer in gold nanoparticles bifunctionalized by tryptophan and riboflavin and its application in fluorescence bioimaging
Colloids Surf B Biointerfaces. 2023 May 12;227:113340. doi: 10.1016/j.colsurfb.2023.113340. Online ahead of print.ABSTRACTGold nanoparticles were functionalized by amino acid tryptophan and vitamin riboflavin - a resonance energy transfer (RET) pair of biomolecules. The presence of the gold nanoparticles resulted in 65% increase in RET efficiency. Because of enhanced RET efficiency, the photobleaching dynamics of the fluorescent molecules at the surface of the nanoparticles is different from that of molecules in solution. The observed effect was used for detection of the functionalized nanoparticles within biological mater...
Source: Colloids and Surfaces - May 18, 2023 Category: Biotechnology Authors: Jelena D Pajovi ć Radovan J Doj čilović Sl ávka Kaščáková Matthieu R éfrégiers Du šan K Božanić Vladimir Djokovi ć Source Type: research
Therapeutic effects of chitosan-embedded vitamin C, E nanoparticles against cisplatin-induced gametogenic and androgenic toxicity in adult male rats
Environ Sci Pollut Res Int. 2021 May 29. doi: 10.1007/s11356-021-14516-y. Online ahead of print.ABSTRACTCisplatin, an anticancer drug used in treating various types of cancers, can cause reproductive toxicities during chemotherapy. Keeping this in view, the present study was designed to investigate the possible protective effects of normal vitamin C and E and vitamin C and E nanoparticles (embedded in chitosan) against cisplatin-induced reproductive toxicities. Vitamins C, E, and their nanoparticles in this regard proved to be an effective therapy. The work aimed to treat cisplatin-induced reproductive toxicities through v...
Source: Environmental Science and Pollution Research International - May 29, 2021 Category: Environmental Health Authors: Naveed Rauf Ayesha Nawaz Hizb Ullah Rahim Ullah Ghulam Nabi Asad Ullah Fazal Wahab Sarwat Jahan Junfen Fu Source Type: research
Thermosensitive chitosan/poly(N-isopropyl acrylamide) nanoparticles embedded in aniline pentamer/silk fibroin/polyacrylamide as an electroactive injectable hydrogel for healing critical-sized calvarial bone defect in aging rat model
Int J Biol Macromol. 2022 May 28:S0141-8130(22)01166-7. doi: 10.1016/j.ijbiomac.2022.05.176. Online ahead of print.ABSTRACTThermosensitive nanoparticles with phase transition abilities upon temperature change have been considered suitable materials in biomedical fields, especially thermo-sensitive drug delivery systems. Moreover, electroactive injectable hydrogel supporting bone regeneration of the elderly will highly be desired in bone tissue engineering applications. Herein, thermosensitive nanoparticles were fabricated using chitosan/poly(N-isopropyl acrylamide) for simvastatin acid delivery. The nanoparticles were inco...
Source: International Journal of Biological Macromolecules - May 31, 2022 Category: Biochemistry Authors: Negin Khaneh Zarrin Fatemeh Mottaghitalab Rui L Reis Subhas C Kundu Mehdi Farokhi Source Type: research
Topical application of a cream containing nanoparticles with vitamin E for radiodermatitis prevention in women with breast cancer: A randomized, triple-blind, controlled pilot trial
CONCLUSIONS: A potential protective effect of a cream containing vitamin E nanoparticles was observed. This pilot study presents initial evidence about the role of a nanoencapsulated antioxidant in preventing radiodermatitis.TRIAL REGISTRATION: No. RBR-784F3Y; UTN-U1111-1201-5923.PMID:36403542 | DOI:10.1016/j.ejon.2022.102230
Source: European Journal of Oncology Nursing - November 20, 2022 Category: Nursing Authors: Fernanda Mateus Queiroz Schmidt Carol Viviana Serna Gonz ález Rodrigo Calixto Mattar Luciana Biagini Lopes Marinilce Fagundes Santos Vera L úcia Conceição de Gouveia Santos Source Type: research
Cellular and Non-cellular Antioxidant Properties of Vitamin E-Loaded Metallic-Quercetin/Polycaprolactone Nanoparticles for the Treatment of Melanogenesis
AAPS PharmSciTech. 2023 Jun 22;24(6):141. doi: 10.1208/s12249-023-02588-7.ABSTRACTInhibition of melanogenesis by quercetin and vitamin E is extensively reported in the literature, independently, with limitations in antioxidant potential owing to less permeation, solubility, decreased bioavailability, and reduced stability. Thus, the aim of the present study was to synthesize a novel complex of metal ions (copper and zinc) with quercetin to enhance antioxidant properties which were confirmed by docking studies. Polycaprolactone-based nanoparticles of the synthesized complex (PCL-NPs, Q-PCL-NPs, Zn-Q-PCL-NPs, Cu-Q-PCL-NPs) w...
Source: AAPS PharmSciTech - June 22, 2023 Category: Drugs & Pharmacology Authors: Nasreen Ramzan Muhammad Azeem Khalid Mahmood Shahid Shah Fazal Rahman Sajid Chughtai Muhammad Hanif Nabeela Ameer Zakia Bashir Farhan Siddique Muhammad Qaisar Source Type: research
Antioxidant and antibacterial activity of silver nanoparticles synthesized by Cestrum nocturnum
ConclusionGreen synthesized silver nanoparticles have strong antioxidant and antibacterial activity due to the presence of bioactive molecules on the surface of silver nanoparticles.
Source: Journal of Ayurveda and Integrative Medicine - August 17, 2018 Category: Complementary Medicine Source Type: research
Alginate/chitosan nanoparticles for encapsulation and controlled release of vitamin B2.
Abstract
This work aims at evaluating encapsulation and controlled release of vitamin B2 from alginate/chitosan nanoparticles. Ionotropic polyelectrolyte pre-gelation was used as production method being chitosan and alginate used as main materials. Nanoparticles were characterized in terms of average size, polydispersity index (PDI), zeta potential and vitamin entrapment efficiency. The average size for alginate/chitosan nanoparticles was 119.5 ± 49.9nm for samples without vitamin B2 and 104.0±67.2nm with the encapsulation of vitamin B2, presenting a PDI of 0.454±0.066 and 0.319±0.068, respectively. The nano...
Source: International Journal of Biological Macromolecules - May 23, 2014 Category: Biochemistry Authors: Azevedo MA, Bourbon AI, Vicente AA, Cerqueira MA Tags: Int J Biol Macromol Source Type: research
