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Total 34619 results found since Jan 2013.

The growth restriction effect of TiCN nanoparticles on Al-Cu-Zr alloys via ultrasonic treatment
This study is especially beneficial for Al alloys that have poisoning phenomenon inoculated by traditional refiner.PMID:34800839 | DOI:10.1016/j.ultsonch.2021.105829
Source: Ultrasonics Sonochemistry - November 20, 2021 Category: Chemistry Authors: Yiwang Jia Dongfu Song Nan Zhou Kaihong Zheng Yanan Fu Da Shu Source Type: research

Selenium-Methionine-Folic Acid Nanoparticles (SeMetFa NPs) and Its In Vivo Efficacy Against Rheumatoid Arthritis
Biol Trace Elem Res. 2023 Sep 8. doi: 10.1007/s12011-023-03840-8. Online ahead of print.ABSTRACTSelenium nanoparticles can be beneficial against rheumatoid arthritis, with limitations in dosage formulation due to their toxicity and low bioavailability. In the present study, we investigated the bioavailability and in vivo efficiency of selenium-methionine-folic acid nanoparticles (SeMetFa NPs) in chronic inflammatory arthritis in rats. The purpose of this study was to develop a therapeutic agent that is of low toxicity and readily available for the maintenance of rheumatoid arthritis. SeMetFa NPs were synthesised by a wet c...
Source: Biological Trace Element Research - September 8, 2023 Category: Biology Authors: Vrundali Shinde Krutika Desai Source Type: research

In vitro characterization of a biocompatible composite based on poly(3-hydroxybutyrate)/hydroxyapatite nanoparticles as a potential scaffold for tissue engineering
J Mech Behav Biomed Mater. 2022 Feb 23;128:105138. doi: 10.1016/j.jmbbm.2022.105138. Online ahead of print.ABSTRACTThe use of regeneration scaffolds has been a promising strategy in the bone tissue engineering area. Among the materials available for this purpose the poly(3-hydroxybutyrate) - PHB stands out for its adequate biocompatibility and osteoinduction capacity. Hydroxyapatite, in turn, has as its main characteristics its ability to increase bioactivity and cell proliferation. Thus, the objective of the present study was to obtain PHB composites with nanohydroxyapatite (Hap) (0.05%, 0.20%, and 0.50%) and evaluate the...
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 1, 2022 Category: Materials Science Authors: Maxwell de Paula Cavalcante Livia Rodrigues de Menezes Elton Jorge da Rocha Rodrigues Maria In ês Bruno Tavares Source Type: research

Assessment of fracture healing properties of lovastatin loaded nanoparticles: preclinical study in rat model.
Abstract Bone fracture, being mainly caused by mechanical stress, requires special and quick attention for a rapid healing. The study presented here aims at formulating nanoparticulate system to overcome the solubility issues of lovastatin. The lovastatin nanoparticles were successfully prepared by ionotropic gelation method using chitosan and tri-polyphosphate as polymers. Thus prepared nanoparticles were found to be smooth and spherical with average particle size of 87 nm and encapsulation efficiency of 86.5%. The in-vitro drug release was found to be almost 89.6% in the first 360 minutes. Artificial fracture wa...
Source: Acta Biochim Pol - March 10, 2019 Category: Biochemistry Authors: Zhu P, Huang G, Zhang B, Zhang W, Dang M, Huang Z Tags: Acta Biochim Pol Source Type: research

Design and Development of Bioinspired Calcium phosphate nanoparticles of MTX: Pharmacodynamic and Pharmacokinetic evaluation.
Authors: Pandey S, Mahtab A, Kumar V, Ahmad FJ, Verma AK, Talegaonkar S Abstract The aim of this investigation is the management of rheumatoid arthritis (RA) by developing methotrexate loaded calcium phosphate nanoparticles (MTX-CAP-NP) and to evaluate pharmacokinetic and pharmacodynamic behaviour in adjuvant induced arthritis model. The nanoparticles were synthesized by wet precipitation method and optimized by Box-Behnken experimental design. MTX-CAP-NPs were characterized by TEM, FTIR, DSC and XRD studies. The particle size, zeta potential and entrapment efficiency of the optimized nanoparticles were found to be...
Source: Drug Development and Industrial Pharmacy - April 3, 2019 Category: Drugs & Pharmacology Tags: Drug Dev Ind Pharm Source Type: research

Relationship between size distribution of synthesized nanoparticles and flow and thermal fields in a flow-type reactor for supercritical hydrothermal synthesis
Publication date: March 2016 Source:The Journal of Supercritical Fluids, Volume 109 Author(s): Ken-ichi Sugioka, Kyohei Ozawa, Masaki Kubo, Takao Tsukada, Seiichi Takami, Tadafumi Adschiri, Katsumi Sugimoto, Nobuyuki Takenaka, Yasushi Saito In this work, CeO2 nanoparticles were synthesized hydrothermally with supercritical water using a tubular flow reactor with three different configurations and various flow rates of the feed solution and supercritical water, and the effects of the reactor configuration and the flow rates of the two streams on the size distributions of the synthesized nanoparticles were investi...
Source: The Journal of Supercritical Fluids - December 9, 2015 Category: Chemistry Source Type: research

Multifunctional upconversion nanoparticles for targeted dual-modal imaging in rat glioma xenograft
Conclusions Targeted UCL and magnetic resonance imaging dual-modal in vivo imaging using Yb3+/Er3+/Li+ codoped NaGdF4 core-shell nanostructure can serve as a platform technology for the next generation of intraoperative probes for image-guided tumor resection.
Source: Journal of Biomaterials Applications - August 12, 2016 Category: Materials Science Authors: Yang, L., Shao, B., Zhang, X., Cheng, Q., Lin, T., Liu, E. Tags: Nanotechnology in Biomaterials Source Type: research

Highly bioactive bone cement microspheres based on α-tricalcium phosphate microparticles/mesoporous bioactive glass nanoparticles: Formulation, physico-chemical characterization and in vivo bone regeneration
Colloids Surf B Biointerfaces. 2022 Jun 20;217:112650. doi: 10.1016/j.colsurfb.2022.112650. Online ahead of print.ABSTRACTCalcium phosphate cement (CPC) is a self-setting, biocompatible and osteoconductive bone cement, however its use as a bone substitute is still limited owing to its low bioactivity (i.e. its slow in vivo resorption and slow new bone formation rate) which is a challenging issue to be addressed. Herein, we report for the first time highly bioactive bone cement microspheres formulated from a cement paste containing α-tricalcium phosphate microparticles (α-TCP) and mesoporous calcium silicate bioactive gla...
Source: Colloids and Surfaces - June 28, 2022 Category: Biotechnology Authors: Ahmed El-Fiqi Joong-Hyun Kim Hae-Won Kim Source Type: research

Effect of Silver Nanoparticles on Physicochemical and Antibacterial Properties of Calcium Silicate Cements.
Abstract Mineral trioxide aggregate (MTA) and Portland cement (PC) are calcium silicate cements. They have similar physicochemical, mechanical and biological properties. The addition of zirconium oxide (ZrO2) to PC provides radiopacity. Silver nanoparticles (AgNPs) may improve some properties of cements. The aim of this study was to evaluate the effect of AgNPs on physicochemical/mechanical properties and antibacterial activity of white MTA (WMTA) and PC associated with ZrO2. The following materials were evaluated: WMTA; PC 70% + ZrO2 30%; WMTA+ AgNPs; and PC 70% + ZrO2 30% + AgNPs. The study evaluated radiopacity...
Source: Braz Dent J - August 31, 2016 Category: Dentistry Authors: Vazquez-Garcia F, Tanomaru-Filho M, Chávez-Andrade GM, Bosso-Martelo R, Basso-Bernardi MI, Guerreiro-Tanomaru JM Tags: Braz Dent J Source Type: research

A Large-Sample Test of a Semi-Automated Clavicle Search Engine to Assist Skeletal Identification by Radiograph Comparison.
Abstract In 2014, a morphometric capability to search chest radiograph databases by quantified clavicle shape was published to assist skeletal identification. Here, we extend the validation tests conducted by increasing the search universe 18-fold, from 409 to 7361 individuals to determine whether there is any associated decrease in performance under these more challenging circumstances. The number of trials and analysts were also increased, respectively, from 17 to 30 skeletons, and two to four examiners. Elliptical Fourier analysis was conducted on clavicles from each skeleton by each analyst (shadowgrams trimme...
Source: Journal of Forensic Sciences - December 22, 2016 Category: Forensic Medicine Authors: D'Alonzo SS, Guyomarc'h P, Byrd JE, Stephan CN Tags: J Forensic Sci Source Type: research

Radiopacity of Mineral Trioxide Aggregate with and without Inclusion of Silver Nanoparticles.
CONCLUSION: Silver NPs changed the radiopacity of WMTA, being more evident in WMTA + NP powder at 1% weight. CLINICAL SIGNIFICANCE: The low radiopacity of MTA makes it difficult for any radiographic observation. The Ag NPs appear as an alternative, being an excellent radiopacifier as they have excellent antimicrobial property and relatively low toxicity. PMID: 28621272 [PubMed - in process]
Source: J Contemp Dent Pract - June 1, 2017 Category: Dentistry Authors: Mendes MS, Resende LD, Pinto CA, Raldi DP, Cardoso FG, Habitante SM Tags: J Contemp Dent Pract Source Type: research