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Specialty: Cancer & Oncology
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Total 126553 results found since Jan 2013.
Antiproliferative activity of Camellia sinensis mediated silver nanoparticles on three different human cancer cell lines
Conclusion: The superior activity of the silver nanoparticles may be due to its spherical shape and smaller particle size 10–30 nm as confirmed from NTA and TEM analysis. The data obtained in the study reveal the potent therapeutic value of biogenic silver nanoparticles.
Source: Journal of Cancer Research and Therapeutics - November 28, 2018 Category: Cancer & Oncology Authors: Anu Yadav Vijay D Mendhulkar Source Type: research
Overview of inorganic nanoparticles: An expanding horizon in tumor therapeutics
CONCLUSION: This review paper concludes that inorganic nanoparticles may be better alternatives to conventional approaches for the treatment of cancer. However, their presence in global pharmaceutical markets will be governed by the development of novel scale-up techniques and clinical evaluation.PMID:36200151 | DOI:10.2174/1574892817666221005094423
Source: Recent Patents on Anti-Cancer Drug Discovery - October 6, 2022 Category: Cancer & Oncology Authors: Lalit Kumar Shivani Verma Puneet Utreja Dinesh Kumar Source Type: research
Importance of radiolytic reactions during high-LET irradiation modalities: LET effect, role of O 2 and radiosensitization by nanoparticles
This article reviews radiation chemistry processes induced by high-linear energy transfer (LET) radiation. The first part gives a short historical introduction and defines the essential concepts of radiation chemistry. It is aimed at radiobiologists in search of basics in this discipline, to link to their biological observations. Then, special focus is done on LET effect, oxygen effect and nanoparticles as these parameters can influence the success of radiotherapy. The embraced point of view is the one from a chemist as involved molecular reactions in water are detailed and revealed, for example, how dioxygen can be produc...
Source: Cancer Nanotechnology - May 12, 2019 Category: Cancer & Oncology Source Type: research
Mesoporous silica nanoparticles as a prospective and promising approach for drug delivery and biomedical applications.
CONCLUSION: Through approaching to this review, the researchers can be aware of many new synthetic methods, smart designs proposed in recent year and remained question of MSNs at present.
PMID: 30520373 [PubMed - as supplied by publisher]
Source: Current Cancer Drug Targets - December 5, 2018 Category: Cancer & Oncology Authors: Pu X, Li J, Qiao P, Li M, Wang H, Zong L, Yuan Q, Duan S Tags: Curr Cancer Drug Targets Source Type: research
In Vivo Efficacy and Toxicity of Curcumin Nanoparticles in Breast Cancer Treatment: A Systematic Review
Breast cancer is one of the most prevalent types of malignant tumors in the world, resulting in a high incidence of death. The development of new molecules and technologies aiming to apply more effective and safer therapy strategies has been intensively explored to overcome this situation. The association of nanoparticles with known antitumor compounds (including plant-derived molecules such as curcumin) has been considered an effective approach to enhance tumor growth suppression and reduce adverse effects. Therefore, the objective of this systematic review was to summarize published data regarding evaluations about effic...
Source: Frontiers in Oncology - March 9, 2021 Category: Cancer & Oncology Source Type: research
Size and Shape Directed Novel Green Synthesis of Plasmonic Nanoparticles Using Bacterial Metabolites and Their Anticancer Effects
Front Microbiol. 2022 Apr 11;13:866849. doi: 10.3389/fmicb.2022.866849. eCollection 2022.ABSTRACTThe growing need for developing new synthesis methods of plasmonic nanoparticles (PNPs) stems from their various applications in nanotechnology. As a result, a variety of protocols have been developed for the synthesis of PNPs of different shapes, sizes, and compositions. Though widely practiced, the chemical synthesis of PNPs demands stringent control over the experimental conditions, often employs environmentally hazardous chemicals for surface stabilization, and is frequently energy-intensive. Additionally, chemically obtain...
Source: Cancer Control - May 2, 2022 Category: Cancer & Oncology Authors: Snehal Patil Murali Sastry Atul Bharde Source Type: research
Protective Effects of Coenzyme Q10 Along with Fe < sub > 2 < /sub > O < sub > 3 < /sub > Nanoparticles On Sperm Parameters in Rats with Scrotal Hyperthermia: Effects of CoQ 10 and Fe < sub > 2 < /sub > O < sub > 3 < /sub > Nanoparticles On Sperm Parameters
Conclusion: Our findings suggest that CoQ10, along with Fe2O3 nanoparticles, has a protective effect against spermatogenic cell death induced by SH. Thus, green synthesis of nanoparticles with the administration of antioxidants, including CoQ10 is recommended for the treatment of SH.PMID:36408487 | PMC:PMC9651174 | DOI:10.31661/gmj.v11i.2046
Source: Cancer Control - November 21, 2022 Category: Cancer & Oncology Authors: Mahshid Deldar Abad Paskeh Nahid Babaei Maliheh Entezari Mehrdad Hashemi Abbas Doosti Source Type: research
Immunomodulatory roles of selenium nanoparticles: Novel arts for potential immunotherapy strategy development
Front Immunol. 2022 Jul 26;13:956181. doi: 10.3389/fimmu.2022.956181. eCollection 2022.ABSTRACTCurrent chemotherapy strategies used in clinic appear with lots of disadvantages due to the low targeting effects of drugs and strong side effects, which significantly restricts the drug potency, causes multiple dysfunctions in the body, and even drives the emergence of diseases. Immunotherapy has been proved to boost the body's innate and adaptive defenses for more effective disease control and treatment. As a trace element, selenium plays vital roles in human health by regulating the antioxidant defense, enzyme activity, and im...
Source: Cancer Control - August 12, 2022 Category: Cancer & Oncology Authors: Gengshi Chen Fen Yang Shuhao Fan Hua Jin Kangsheng Liao Xuemeng Li Gan-Bin Liu Jing Liang Junai Zhang Jun-Fa Xu Jiang Pi Source Type: research
Radionuclide < sup > 131 < /sup > I-labeled albumin-indocyanine green nanoparticles for synergistic combined radio-photothermal therapy of anaplastic thyroid cancer
CONCLUSIONS: In summary, 131I-HSA-ICG nanoparticles could successfully perform dual-modality imaging and treatment of ATC, which provides a new direction for the future treatment of iodine-refractory thyroid cancer.PMID:35957867 | PMC:PMC9358776 | DOI:10.3389/fonc.2022.889284
Source: Cancer Control - August 12, 2022 Category: Cancer & Oncology Authors: Xuemei Zhang Ziyu Yan Zhaowei Meng Ning Li Qiang Jia Yiming Shen Yanhui Ji Source Type: research
The effect of & lt;em & gt;Lactobacillus casei & lt;/em & gt; and & lt;em & gt;Bacillus coagulans & lt;/em & gt; probiotics on liver damage induced by silver nanoparticles and expression of Bax, Bcl2 and Caspase 3 genes in male rats
In this study, we aimed to evaluate the effect of Bacillus coagulans and Lactobacillus casei probiotics on liver damage induced by silver nanoparticles and expression of Bax, Bcl2 and Caspase 3 genes in rats. 32 adult male Wistar rats were divided into four healthy groups (control), the group receiving silver nanoparticles treated with L. casei, the group receiving silver nanoparticles treated with B. coagulans and the group receiving only silver nanoparticles. The effect of nanoparticles was induced by intraperitoneal injection of silver nanoparticles prepared from nettle at a dose of 50 mg/kg and entered the liver tissue...
Source: Cancer Control - September 14, 2022 Category: Cancer & Oncology Authors: Reyhaneh Oliaei Zahra Keshtmand Ronak Shabani Source Type: research
Nanoparticles for Lymph Node-Directed Delivery
Pharmaceutics. 2023 Feb 8;15(2):565. doi: 10.3390/pharmaceutics15020565.ABSTRACTLymph nodes are organs that control immune cells and provide a major pathway for primary tumors to metastasize. A nanoparticles-based strategy has several advantages that make it suitable for achieving effective lymphatic delivery. First, the size of nanoparticles can be tailored to meet a size range appropriate for lymphatic migration. In addition, functionalized nanoparticles can target cells of interest for delivery of drugs or imaging probes. Existing lymph node contrast agents map all lymph nodes regardless of metastasis status; however, b...
Source: Cancer Control - February 25, 2023 Category: Cancer & Oncology Authors: Jaeseong Lee Sungtaek Kang Hyeseon Park Jeong Gil Sun Eun Chae Kim Gayong Shim Source Type: research
