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Specialty: Drugs & Pharmacology
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Total 127493 results found since Jan 2013.
Oral delivery of capsaicin using MPEG-PCL nanoparticles
mp; Wei-ming Zhang
Source: Acta Pharmacologica Sinica - January 5, 2015 Category: Drugs & Pharmacology Authors: Wei PengXin-yi JiangYuan ZhuE Omari-SiawWen-wen DengJiang-nan YuXi-ming XuWei-ming Zhang Tags: MPEG-PCL nanoparticles capsaicin pharmacokinetics gastric mucosa irritation Source Type: research
Ergosterol-loaded poly(lactide-co-glycolide) nanoparticles with enhanced in vitro antitumor activity and oral bioavailability
an Yu & Xi-ming Xu
Source: Acta Pharmacologica Sinica - May 31, 2016 Category: Drugs & Pharmacology Authors: Hui-yun ZhangCaleb Kesse FirempongYuan-wen WangWen-qian XuMiao-miao WangXia CaoYuan ZhuShan-shan TongJiang-nan YuXi-ming Xu Tags: ergosterol plant sterol nanoparticles anti-tumor agent oral bioavailability pharmacokinetics drug tissue distribution Source Type: research
Silibinin and indocyanine green-loaded nanoparticles inhibit the growth and metastasis of mammalian breast cancer cells in vitro
ang & Ya-ping Li
Source: Acta Pharmacologica Sinica - June 30, 2016 Category: Drugs & Pharmacology Authors: Hui-ping SunJing-han SuQing-shuo MengQi YinZhi-wen ZhangHai-jun YuPeng-cheng ZhangSi-ling WangYa-ping Li Tags: breast cancer 4T1 mammalian breast cancer cells metastasis nanoparticles silibinin photothermal therapy NIR laser irradiation Source Type: research
Smart nanoparticles improve therapy for drug-resistant tumors by overcoming pathophysiological barriers
ai-jun Yu
Source: Acta Pharmacologica Sinica - January 3, 2017 Category: Drugs & Pharmacology Authors: Jian-ping Liu Ting-ting Wang Dang-ge Wang An-jie Dong Ya-ping Li Hai-jun Yu Tags: solid tumors chemotherapy drug resistance pathophysiological barriers tumor microenvironment nanomedicine smart nanoparticles Source Type: research
Dual-targeted hybrid nanoparticles of synergistic drugs for treating lung metastases of triple negative breast cancer in mice
Xiao Yu Wu
Source: Acta Pharmacologica Sinica - June 1, 2017 Category: Drugs & Pharmacology Authors: Tian Zhang Preethy Prasad Ping Cai Chunsheng He Dan Shan Andrew Michael Rauth Xiao Yu Wu Tags: polymer-lipid hybrid nanoparticles triple negative breast cancer human MDA-MB-231 cells lung metastases doxorubicin mitomycin C synergistic action dual-targeted RGD Source Type: research
Nanoparticles as an effective drug delivery system in COVID-19
CONCLUSION: Our current studies reveal that nanoparticles may prove very helpful in the delivery of drugs for Covid-19 treatment. Many cases showed that patients, where drugs are delivered with the help of nanoparticles, produced very few side effects.PMID:34649334 | DOI:10.1016/j.biopha.2021.112162
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - October 15, 2021 Category: Drugs & Pharmacology Authors: Neehasri Kumar Chowdhury None Deepika Reshma Choudhury Gaurav Ambadas Sonawane Shankar Mavinamar Xiaoming Lyu Ramendra Pati Pandey Chung-Ming Chang Source Type: research
The Biogenetic Synthesis of Metallic Nanoparticles and the Role They Play in Anti-inflammatory Drug Treatment
CONCLUSION: The current research focuses on metallic nanoparticles employed as anti-inflammatory medication molecules, although nanoparticles have applications in various areas (medicine, chemical engineering, and agriculture). Nanoparticles have a large surface-to-volume ratio, which can help them to penetrate cell membranes, and because of their solid ligand-binding capabilities, nanoparticles have been used in the medical treatment of inflammatory pathologies.PMID:37464822 | DOI:10.2174/1570163820666230718123544
Source: Current Drug Discovery Technologies - July 19, 2023 Category: Drugs & Pharmacology Authors: Meena Kurup Mohan Kumar Sambathkumar Ramanathan Margnat Chandra Source Type: research
Recent patents, regulatory issues, and toxicity of nanoparticles in neuronal disorders.
CONCLUSION: Although nanoparticles have unique physical and chemical properties that explain the broad range of application for the central nervous system, they can also manifest neurotoxic effects due to cell necrosis, a generation of free radicals, immune responses and neuroinflammation. Thus, this review highlights on risk assessment, safety regulations and regulatory guidelines of nanoparticles which may reduce adverse reactions in humans and animals.
PMID: 33305703 [PubMed - as supplied by publisher]
Source: Current Drug Metabolism - December 10, 2020 Category: Drugs & Pharmacology Authors: Muheem A, Jahangir MA, Jaiswal CP, Jafar M, Ahmad MZ, Ahmad J, Warsi MH Tags: Curr Drug Metab Source Type: research
New strategies in the treatment of diseases caused by Acanthamoeba based on nanoparticles: a systematic review
CONCLUSION: This study showed that chlorhexidine and other plant metabolites loaded with silver and gold nanoparticles increase the anti-Acanthambae activity of these nanoparticles. However, green synthesized nanoparticles based on stabilization by plant gums, loaded with citrus fruits flavonoids hesperidin (HDN) and naringin (NRG), showed the best anti-Acanthambae effect. Nevertheless, further studies should be performed to determine their safety for human use.PMID:36372923 | DOI:10.2174/2772432818666221111155119
Source: Pharmacological Reviews - November 14, 2022 Category: Drugs & Pharmacology Authors: Pegah Shakib Hamed Kalani Muhammad Tahir Aleem Roghiyeh Faridnia Mustafa Zebardast Pour Kobra Moradpour Kourosh Cheraghipour Source Type: research
The Potential of Chitosan in Nanomedicine: An Overview of the Cytotoxicity of Chitosan Based Nanoparticles
The unique properties and applications of nanotechnology in targeting drug delivery, cosmetics, fabrics, water treatment and food packaging have received increased focus the last two decades. The application of nanoparticles in medicine is rapidly evolving, requiring careful investigation of toxicity before clinical use. Chitosan, a derivative of the natural polysaccharide chitin, has become increasingly relevant in modern medicine because of its unique properties as a nanoparticle. Chitosan is already widely used as a food additive and in food packaging, bandages and wound dressings. Thus, with an increasing application w...
Source: Frontiers in Pharmacology - May 4, 2022 Category: Drugs & Pharmacology Source Type: research
Evaluation of biologically synthesized Au-CuO and CuO-ZnO nanoparticles against glioma cells and microorganisms
Publication date: Available online 17 December 2018Source: Saudi Pharmaceutical JournalAuthor(s): Renata Dobrucka, Mariusz Kaczmarek, Małgorzata Łagiedo, Agata Kielan, Jolanta DlugaszewskaAbstractDue to the search for new methods of producing bimetallic nanoparticles, in this work, we have conducted a biological synthesis of Au-CuO and CuO-ZnO nanoparticles using Cnici benedicti. The synthesized Au-CuO and CuO-ZnO nanoparticles were also analyzed in terms of their antibacterial activity, as well as their influence on cell viability, using two specific cell lines: C6 rat brain glioma (ATCC® CCL-107 ™) and T98G human gl...
Source: Saudi Pharmaceutical Journal - December 18, 2018 Category: Drugs & Pharmacology Source Type: research
Phytochemicals Formulated as Nanoparticles: Inventions,Recent Patents and Future Prospects.
CONCLUSION: If bioavailability constraint is overcome, diseases like cancer, alzheimer, diabetes, liver disorder etc. can be effectively targeted. By doing so, the largely affected society, will breathe the relief. The present article is an attempt to elaborate and conclude on how nanoparticles have been serving as a tool to enhance the effectiveness of phytochemicals, by solubilization, dissolution and consequent bioavailability enhancements, along with in vivo targeting. To further facilitate understanding, the review has been structured as disease/disorder and phytochemical wise with focus on their nanoparticles.
PM...
Source: Recent Patents on Drug Delivery and Formulation - November 24, 2017 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Combination Ointment Containing Solid Tranilast Nanoparticles and Dissolved Sericin Is Efficacious for Treating Skin Wound-Healing Deficits and Redness in Diabetic Rats.
In conclusion, we have adapted kinetic analyses to skin wound healing in rats, and found these analyses to be useful as an index of wound healing ability by a wound-healing drug. In addition, we show that treatment with the TS-combination ointment enhances the skin wound healing rate and reduces redness. These findings provide information significant to the search for new wound-healing therapies and for the design of wound-healing drugs.
PMID: 28381799 [PubMed - in process]
Source: Biological and Pharmaceutical Bulletin - April 8, 2017 Category: Drugs & Pharmacology Authors: Nagai N, Ogata F, Deguchi S, Ueno A, Kawasaki N, Ito Y Tags: Biol Pharm Bull Source Type: research
