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Total 19746 results found since Jan 2013.

Can Nanoparticles in Homeopathic Remedies Enhance Phototherapy of Cancer? A Hypothetical Model
Homeopathy. 2021 Nov 17. doi: 10.1055/s-0041-1735581. Online ahead of print.ABSTRACTThe continuous rise in cancer incidence places a massive burden on the health sector to increase efforts in the fight against cancer. As a holistic complementary medicine modality, homeopathy has the potential to assist in the supportive and palliative treatment of cancer patients. Recent empirical studies demonstrate the presence of silica and original source nanoparticles in ultra-high dilutions of several homeopathic medicines. Recent studies have also demonstrated the efficacy of phototherapy in inducing the ablation of cancer cells thr...
Source: Homeopathy - November 17, 2021 Category: Complementary Medicine Authors: Ayesha Loonat Janice Pellow Heidi Abrahamse Rahul Chandran Source Type: research

Attenuation of Experimental Autoimmune Neuritis with Locally Administered Lovastatin ‐Encapsulating PLGA Nanoparticles
This study provides the first proof‐of‐concept approach for the application of a nanoparticle‐based local drug delivery platform for the management of inflammatory demyelinating diseases, including AIDP/GBS. This article is protected by copyright. All rights reserved.
Source: Journal of Neurochemistry - September 30, 2016 Category: Neurology Authors: Kelly A. Langert, Bruktawit Goshu, Evan B. Stubbs Tags: Original Article Source Type: research

Co-designing Community Out-of-hours Palliative Care Services: A systematic literature search and review
CONCLUSION: Incorporating patients, families and carers priorities and preferences in the planning and designing of out-of-hours palliative care service is needed for service providers to deliver care that is more patient-centred. Adopting the principles of co-design may improve how out-of-hours care scan be delivered.PMID:36349547 | DOI:10.1177/02692163221132089
Source: Palliative Medicine - November 9, 2022 Category: Palliative Care Authors: Christine Low Pathmavathy Namasivayam Tony Barnett Source Type: research

Design and Characterization of Metformin-Loaded Solid Lipid Nanoparticles for Colon Cancer.
Abstract Colorectal cancer is a global concern, and its treatment is fraught with non-selective effects including adverse side effects requiring hospital visits and palliative care. A relatively safe drug formulated in a bioavailability enhancing and targeting delivery platform will be of significance. Metformin-loaded solid lipid nanoparticles (SLN) were designed, optimized, and characterized for particle size, zeta potential, drug entrapment, structure, crystallinity, thermal behavior, morphology, and drug release. Optimized SLN were 195.01 ± 6.03 nm in size, -17.08 ± 0.95 mV with regard to surface c...
Source: AAPS PharmSciTech - March 14, 2016 Category: Drugs & Pharmacology Authors: Ngwuluka NC, Kotak DJ, Devarajan PV Tags: AAPS PharmSciTech Source Type: research

Development and validation of search filters to find articles on palliative care in bibliographic databases.
CONCLUSION:: Our search filters can support literature searches in the field of palliative care. Our specific filter retrieves 93.7% of relevant articles, while 45% of the retrieved articles are relevant. This filter can be used to find answers to questions when time is limited. Our sensitive filter finds 99.6% of all relevant articles and may, for instance, help conducting systematic reviews. Both filters perform better than prior developed search filters in the field of palliative care. PMID: 30688143 [PubMed - as supplied by publisher]
Source: Palliative Medicine - January 28, 2019 Category: Palliative Care Authors: Rietjens JA, Bramer WM, Geijteman EC, van der Heide A, Oldenmenger WH Tags: Palliat Med Source Type: research

Palliative effect of Moringa olifera-mediated zinc oxide nanoparticles against acrylamide-induced neurotoxicity in rats
Food Chem Toxicol. 2022 Nov 25:113537. doi: 10.1016/j.fct.2022.113537. Online ahead of print.ABSTRACTRepeated acrylamide (ACR) exposure in experimental animals and humans causes variable degrees of neuronal damage. Because of its unique features, several green synthesized nanomaterials are explored for neuromodulatory activity. Hence, this study investigated the effect of green synthesized zinc oxide nanoparticles using Moriga olifera leaves extract (MO-ZnONP) against acrylamide (ACR)-induced neurobehavioral and neurotoxic impacts in rat. Forty male Sprague Dawley rats were distributed into four groups orally given distill...
Source: Food and Chemical Toxicology - November 28, 2022 Category: Food Science Authors: Naief Dahran Yasmina M Abd El-Hakim Amany Abdel-Rahman Mohamed Marwa M Abd-Elsalam Enas N Said Mohamed M M Metwally Ahmed E Abdelhamid Bayan A Hassan Mohammed Alsieni Manal E Alosaimi Maram Hussen Abduljabbar Eman S El-Shetry Source Type: research

Developing a computerised search to help UK General Practices identify more patients for palliative care planning: a feasibility study
Conclusions: It is possible to significantly improve the identification of patients for palliative care needs assessment using a computerised search however barriers remain to GPs’ finding it acceptable. Time-efficient systems were important as was a generic tool for anticipatory care planning not linked to ‘palliative’ care.
Source: BMC Family Practice - August 8, 2015 Category: Primary Care Authors: Bruce MasonKirsty BoydScott MurrayJohn SteynPaul CormieMarilyn KendallDan MundayDavid WellerShirley FifePeter MurchieChristine Campbell Source Type: research

Endoscopic ultrasound guided injection of iron oxide magnetic nanoparticles for liver and pancreas: a feasibility study in pigs.
CONCLUSIONS: IONs have been widely studied for both diagnostic and therapeutic purposes. Their injection through EUS-guidance may develop new diagnosis strategies as well as curative or palliative therapies in pancreatic and liver tumors. PMID: 27239648 [PubMed - in process]
Source: Medical Ultrasonography - May 31, 2016 Category: Radiology Tags: Med Ultrason Source Type: research

Dual Effect of Prussian Blue Nanoparticles on A β40 Aggregation: β-Sheet Fibril Reduction and Copper Dyshomeostasis Regulation.
Dual Effect of Prussian Blue Nanoparticles on Aβ40 Aggregation: β-Sheet Fibril Reduction and Copper Dyshomeostasis Regulation. Biomacromolecules. 2021 Jan 08;: Authors: Kowalczyk J, Grapsi E, Espargaró A, Caballero AB, Juárez-Jiménez J, Busquets MA, Gamez P, Sabate R, Estelrich J Abstract Alzheimer's disease (AD), affecting almost 50 million individuals worldwide, is currently the first cause of dementia. Despite the tremendous research efforts in the last decade, only four supportive or palliative drugs, namely, acetylcholinesterase (AChE) inhibitors donepezil, galantamine, and rivastigmine and ...
Source: Biomacromolecules - January 8, 2021 Category: Biochemistry Authors: Kowalczyk J, Grapsi E, Espargaró A, Caballero AB, Juárez-Jiménez J, Busquets MA, Gamez P, Sabate R, Estelrich J Tags: Biomacromolecules Source Type: research

What People Search for When Browsing "Doctor Google." An Analysis of Search Trends in Italy after the Law on Pain.
Authors: Miceli L, Bednarova R, Bednarova I, Rizzardo A, Cobianchi L, Dal Mas F, Biancuzzi H, Bove T, Dal Moro F, Zattoni F Abstract Italy adopted a law on chronic pain in March 2010, which focused on detection and management of this symptom, that affects approximately 25% of the population. The aim of this study is to analyze the interest of the Italian population in palliative care and chronic pain and to understand whether the Law 38/2010 made an impact on the internet search on chronic pain. Five research parameters were included using Google Trends (chronic pain, anti-inflammatory drugs, opioids, fibromyalgia,...
Source: Journal of Pain and Palliative Care Pharmacotherapy - February 13, 2021 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research

Musculoskeletal pain in older adults at the end-of-life: a systematic search and critical review of the literature with priorities for future research
Conclusion: Priorities for future research include high quality epidemiological studies to establish the prevalence, natural history, impact, assessment, patient priorities and outcomes associated with musculoskeletal pain in the end of life period, and intervention research that provides an evidence base for treatment.
Source: BMC Palliative Care - Latest articles - July 25, 2013 Category: Palliative Care Authors: Alison LillieSue ReadChristian MallenPeter CroftJohn McBeth Source Type: research

Voluntary stopping of eating and drinking at the end of life - a 'systematic search and review' giving insight into an option of hastening death in capacitated adults at the end of life
Conclusions: The included articles provide marginal insight into VSED for hastening death. Research is needed in the field of theory-building and should be based on qualitative studies from different perspectives (patient, family members, and healthcare workers) about physiological processes during VSED, and about the prevalence and magnitude of VSED. Based on these findings supportive care interventions for patients and family members and recommendations for healthcare staff should be developed and tested.
Source: BMC Palliative Care - Latest articles - January 8, 2014 Category: Palliative Care Authors: Nata¿a Ivanovi¿Daniel BücheAndré Fringer Source Type: research